Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington's disease

Brain

Volumn 138, Issue 11, 2015, Pages 3327-3344

  McColgan, Peter ^a   Seunarine, Kiran K ^b   Razi, Adeel ^a,c   Cole, James H ^d   Gregory, Sarah ^a   Durr, Alexandra ^e   Roos, Raymund A C ^f   Stout, Julie C ^g   Landwehrmeyer, Bernhard ^h   Scahill, Rachael I ^a   Clark, Chris A ^b   Rees, Geraint ^a   Tabrizi, Sarah J ^a,i  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NED UNIVERSITY OF ENGINEERING AND TECHNOLOGY   (Pakistan)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e SORBONNE UNIVERSITÉ   (France)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^g MONASH UNIVERSITY   (Australia)

^h UNIVERSITY OF ULM   (Germany)

ⁱ NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Huntington's disease; rich club; tractography

Indexed keywords

ADULT; ANTERIOR CINGULATE; ARTICLE; BASAL GANGLION; BRAIN REGION; CAUDATE NUCLEUS; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DEGENERATIVE DISEASE; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; HUNTINGTON CHOREA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; NERVE CELL NETWORK; NEUROANATOMY; NEUROPATHOLOGY; PATHOPHYSIOLOGY; PRECUNEUS; PRIORITY JOURNAL; PUTAMEN; STATISTICAL ANALYSIS; SUPRAMARGINAL GYRUS; THALAMUS; TRACTOGRAPHY; BRAIN; BRAIN CORTEX; CASE CONTROL STUDY; DIFFUSION TENSOR IMAGING; IMAGE PROCESSING; MIDDLE AGED; NEOSTRIATUM; NERVE TRACT; PATHOLOGY;

ADULT; BASAL GANGLIA; BRAIN; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; CEREBRAL CORTEX; DIFFUSION MAGNETIC RESONANCE IMAGING; DIFFUSION TENSOR IMAGING; FEMALE; HUMANS; HUNTINGTON DISEASE; IMAGE PROCESSING, COMPUTER-ASSISTED; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEOSTRIATUM; NEURAL PATHWAYS; PUTAMEN; THALAMUS;

EID: 84947802721     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awv259     Document Type: Article

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