Abnormal rich club organization and functional brain dynamics in schizophrenia

JAMA Psychiatry

Volumn 70, Issue 8, 2013, Pages 783-792

  Van Den Heuvel, Martijn P ^a,c   Sporns, Olaf ^b   Collin, Guusje ^a   Scheewe, Thomas ^a   Mandl, René C W ^a   Cahn, Wiepke ^a   Goni, Joaquín ^b   Pol, Hilleke E Hulshoff ^a   Kahn, René S ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b INDIANA UNIVERSITY   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FRONTAL LOBE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; INSULA; NUCLEAR MAGNETIC RESONANCE SCANNER; PARIETAL CORTEX; PRECUNEUS; SCHIZOPHRENIA; SUPERIOR FRONTAL CORTEX; SUPERIOR PARIETAL CORTEX; UNIVERSITY HOSPITAL; WHITE MATTER;

EID: 84881169556     PISSN: 2168622X     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapsychiatry.2013.1328     Document Type: Article

References (65)

1. Hagmann P, Cammoun L, Gigandet X, et al. Mapping the structural core of human cerebral cortex. PLoS Biol. 2008;6(7):e159.
2. Sporns O, Chialvo DR, Kaiser M, Hilgetag CC. Organization, development and function of complex brain networks. Trends Cogn Sci. 2004;8(9):418-425. (Pubitemid 39179905)
3. van den Heuvel MP, Stam CJ, Kahn RS, Hulshoff Pol HE. Efficiency of functional brain networks and intellectual performance. J Neurosci. 2009;29(23): 7619-7624.
4. Salvador R, Suckling J, Schwarzbauer C, Bullmore E. Undirected graphs of frequency-dependent functional connectivity in whole brain networks. Philos Trans R Soc Lond B Biol Sci. 2005;360(1457):937-946. (Pubitemid 41672855)
5. Sporns O. The human connectome: A complex network. Ann N Y Acad Sci. 2011;1224:109-125.
6. Sporns O, Tononi G, Kter R. The human connectome: A structural description of the human brain. PLoS Comput Biol. 2005;1(4):e42.
7. Li Y, Liu Y, Li J, et al. Brain anatomical network and intelligence. PLoS Comput Biol. 2009;5(5): E1000395.
8. Bassett DS, Bullmore ET, Meyer-Lindenberg A, Apud JA,Weinberger DR, Coppola R. Cognitive fitness of cost-efficient brain functional networks. Proc Natl Acad Sci U S A. 2009;106(28):11747-11752.
9. Fornito A, Zalesky A, Pantelis C, Bullmore ET. Schizophrenia, neuroimaging and connectomics. Neuroimage. 2012;62(4):2296-2314.
10. van den Heuvel MP, Kahn RS. Abnormal brain wiring as a pathogenetic mechanism in schizophrenia. Biol Psychiatry. 2011;70(12): 1107-1108.
11. Stephan KE, Baldeweg T, Friston KJ. Synaptic plasticity and dysconnection in schizophrenia. Biol Psychiatry. 2006;59(10):929-939. (Pubitemid 44288017)
12. Bleuler E. Dementia Praecox or the Group of Schizophrenias. New York, NY: International Universities Press; 1911.
13. Kanaan RA, Kim JS, Kaufmann WE, Pearlson GD, Barker GJ, McGuire PK. Diffusion tensor imaging in schizophrenia. Biol Psychiatry. 2005;58(12): 921-929. (Pubitemid 41790701)
14. Rosenberger G, Kubicki M, Nestor PG, et al. Age-related deficits in fronto-temporal connections in schizophrenia: A diffusion tensor imaging study. Schizophr Res. 2008;102(1-3):181-188.
15. Voineskos AN, Lobaugh NJ, Bouix S, et al. Diffusion tensor tractography findings in schizophrenia across the adult lifespan. Brain. 2010;133(pt 5):1494-1504.
16. Ellison-Wright I, Bullmore E.Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophr Res. 2009;108(1-3):3-10.
17. Nestor PG, Kubicki M, Spencer KM, Niznikiewicz M, McCarley RW, Shenton ME. Attentional networks and cingulum bundle in chronic schizophrenia. Schizophr Res. 2007;90(1-3): 308-315. (Pubitemid 46188517)
18. Kubicki M, Park H,Westin CF, et al. DTI and MTR abnormalities in schizophrenia: Analysis of white matter integrity. Neuroimage. 2005;26(4): 1109-1118. (Pubitemid 40806489)
19. Fujiwara H, Namiki C, Hirao K, et al. Anterior and posterior cingulum abnormalities and their association with psychopathology in schizophrenia: A diffusion tensor imaging study. Schizophr Res. 2007;95(1-3):215-222. (Pubitemid 47313639)
20. Whitfield-Gabrieli S, Thermenos HW,Milanovic S, et al. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci U S A. 2009;106(4):1279-1284.
21. MannellMV, Franco AR, Calhoun VD, Canive JM, Thoma RJ,Mayer AR. Resting state and task-induced deactivation: Amethodological comparison in patients with schizophrenia and healthy controls. Hum Brain Mapp. 2009;31(3): 424-437.
22. Broyd SJ, Demanuele C, Debener S, Helps SK, James CJ, Sonuga-Barke EJ. Default-mode brain dysfunction in mental disorders: A systematic review. Neurosci Biobehav Rev. 2009;33(3): 279-296.
23. Bluhm RL,Miller J, Lanius RA, et al. Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: Anomalies in the default network. Schizophr Bull. 2007;33(4): 1004-1012. (Pubitemid 47216653)
24. Williamson P. Are anticorrelated networks in the brain relevant to schizophrenia? Schizophr Bull. 2007;33(4):994-1003. (Pubitemid 47216647)
25. Garrity AG, Pearlson GD, McKiernan K, Lloyd D, Kiehl KA, Calhoun VD. Aberrant "default mode" functional connectivity in schizophrenia. Am J Psychiatry. 2007;164(3):450-457. (Pubitemid 46513159)
26. Sporns O, Honey CJ, Kter R. Identification and classification of hubs in brain networks. PLoS One. 2007;2(10):e1049.
27. Tomasi D, Volkow ND. Functional connectivity density mapping. Proc Natl Acad Sci U S A. 2010;107(21):9885-9890.
28. Vkuti B, CavusogluM, Kullik A, et al. Quantifying the link between anatomical connectivity, gray matter volume and regional cerebral blood flow: An integrative MRI study. PLoS One. 2011;6(4):e14801.
29. van den Heuvel MP, Mandl RCW, Stam CJ, Kahn RS, Hulshoff Pol HE. Aberrant frontal and temperal network structure in schizophrenia: A graph theoretical analysis. J Neurosci. 2010;30(47): 15915-15926.
30. van den Heuvel MP, Stam CJ, Boersma M, Hulshoff Pol HE. Small-world and scale-free organization of voxel-based resting-state functional connectivity in the human brain. Neuroimage. 2008;43(3):528-539.
31. Skudlarski P, Jagannathan K, Anderson K, et al. Brain connectivity is not only lower but different in schizophrenia: A combined anatomical and functional approach. Biol Psychiatry. 2010;68(1): 61-69.
32. LynallME, Bassett DS, Kerwin R, et al. Functional connectivity and brain networks in schizophrenia. J Neurosci. 2010;30(28):9477-9487.
33. Liu Y, LiangM, Zhou Y, et al. Disrupted small-world networks in schizophrenia. Brain. 2008;131(pt 4):945-961. (Pubitemid 351499423)
34. Zalesky A, Fornito A, Harding IH, et al. Whole-brain anatomical networks: Does the choice of nodes matter? Neuroimage. 2010;50(3): 970-983.
35. RubinovM, Bassett DS. Emerging evidence of connectomic abnormalities in schizophrenia. J Neurosci. 2011;31(17):6263-6265.
36. van den Heuvel MP, Sporns O. Rich-club organization of the human connectome. J Neurosci. 2011;31(44):15775-15786.
37. Zamora-Lopez G, Zhou C, Kurths J. Cortical hubs form a module for multisensory integration on top of the hierarchy of cortical networks. Front Neuroinform. 2010;4:1.
38. van den Heuvel MP, Kahn RS, Goni J, Sporns O. A high cost, high capacity backbone for global brain communication. Proc Natl Acad Sci U S A. 2012;109(28):11372-11377.
39. van den Heuvel MP, Mandl RC, Hulshoff Pol HE. Normalized group clustering of resting-state fMRI data. PLoS One. 2008;3(4):e2001.
40. van den Heuvel MP, Mandl RCW, Kahn RS, Hulshoff Pol HE. Functionally linked resting-state networks reflect the underlying structural connectivity architecture of the human brain. Hum Brain Mapp. 2009;30(10):3127-3141.
41. Mandl RC, Schnack HG, Luigjes J, et al. Tract-based analysis ofmagnetization transfer ratio and diffusion tensor imaging of the frontal and frontotemporal connections in schizophrenia. Schizophr Bull. 2008;36(4):778-787.
42. Collin G, Hulshoff Pol HE, Haijma SV, CahnW, Kahn RS, van den Heuvel MP. Impaired cerebellar functional connectivity in schizophrenia patients and their healthy siblings. Front Psychiatry. 2011;2:73.
43. Fischel B, van der Kouwe A, Destrieux C, et al. Automatically parcellating the human cerebral cortex. Cereb Cortex. 2004;14(1):11-22. (Pubitemid 38018050)
44. Van Dijk KR, Sabuncu MR, Buckner RL. The influence of head motion on intrinsic functional connectivity MRI. Neuroimage. 2012;59(1):431-438.
45. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage. 2012;59(3): 2142-2154.
46. Fox MD, Zhang D, Snyder AZ, RaichleME. The global signal and observed anticorrelated resting state brain networks. J Neurophysiol. 2009;101(6):3270-3283.
47. Saad ZS, Gotts SJ, Murphy K, et al. Trouble at rest: How correlation patterns and group differences become distorted after global signal regression. Brain Connectivity. 2012;2(1):25-32.
48. RubinovM, Sporns O. Complex network measures of brain connectivity: Uses and interpretations. Neuroimage. 2010;52(3): 1059-1069.
49. Newman ME. Modularity and community structure in networks. Proc Natl Acad Sci U S A. 2006;103(23):8577-8582. (Pubitemid 43878062)
50. Colizza V, Flammini A, Serrano MA, Vespignani A. Detecting rich-club ordering in complex networks. Nat Phys. 2006;2:110-115. (Pubitemid 43731381)
51. Opsahl T, Colizza V, Panzarasa P, Ramasco JJ. Prominence and control: The weighted rich-club effect. Phys Rev Lett. 2008;101(16):168702.
52. McAuley JJ, da Fontoura Costa L, Caetano TS. Rich-club phenomena across complex network hierachies. Appl Phys Lett. 2007;91:084103.
53. de Reus MA, van den Heuvel MP. Estimating false positives and negatives in brain networks. Neuroimage. 2013;70:402-409.
54. Honey CJ, Sporns O, Cammoun L, et al. Predicting human resting-state functional connectivity from structural connectivity. Proc Natl Acad Sci U S A. 2009;106(6):2035-2040.
55. Bassett DS, Bullmore E, Verchinski BA, Mattay VS,Weinberger DR,Meyer-Lindenberg A. Hierarchical organization of human cortical networks in health and schizophrenia. J Neurosci. 2008;28(37):9239-9248.
56. Zalesky A, Fornito A, Seal ML, et al. Disrupted axonal fiber connectivity in schizophrenia. Biol Psychiatry. 2011;69(1):80-90.
57. Zuo XN, Ehmke R, MennesM, et al. Network centrality in the human functional connectome. Cereb Cortex. 2012;22(8):1862-1875.
58. Kubicki M, McCarley R,Westin CF, et al. A review of diffusion tensor imaging studies in schizophrenia. J Psychiatr Res. 2007;41(1-2):15-30. (Pubitemid 44780754)
59. Zhang Y, Schuff N, Jahng GH, et al. Diffusion tensor imaging of cingulum fibers inmild cognitive impairment and Alzheimer disease. Neurology. 2007;68(1):13-19. (Pubitemid 46058544)
60. Harringer L, van den Heuvel MP, Sporns O. Rich club organization of macaque cerebral cortex and its role in network communication. PLoS ONE. 2012;7(9):e46497.
61. Kubicki M,Westin CF, Maier SE, et al. Uncinate fasciculus findings in schizophrenia: Amagnetic resonance diffusion tensor imaging study. Am J Psychiatry. 2002;159(5):813-820. (Pubitemid 34465056)
62. Zamora-Lopez G, Zhou C, Kurths J. Exploring brain function from anatomical connectivity. Front Neurosci. 2011;5:83.
63. Cabral J, Hugues E, Kringelbach ML, Deco G. Modeling the outcome of structural disconnection on resting-state functional connectivity. Neuroimage. 2012;62(3):1342-1353.
64. Cammoun L, Gigandet X,Meskaldji D, et al. Mapping the human connectome at multiple scales with diffusion spectrum MRI. J Neurosci Methods. 2012;203(2):386-397.
65. Bassett DS, Brown JA, Deshpande V, Carlson JM, Grafton ST. Conserved and variable architecture of human white matter connectivity. Neuroimage. 2011;54(2):1262-1279.