Inhibition of the 26S proteasome by peptide mimics of the coiled-coil region of its ATPase subunits

Biochemical and Biophysical Research Communications

Volumn 468, Issue 1-2, 2015, Pages 143-150

  Inobe, Tomonao ^a   Genmei, Reiko ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Coiled coil; Inhibitor; Peptide; Proteasome; Protein degradation; Rpt subunit

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIFUNGAL AGENT; GALACTOSE; GLUTATHIONE TRANSFERASE; LEUCINE; LEUCINE 2; MALTOSE BINDING PROTEIN; PEPTIDE; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN; RPT1 COILED COIL PEPTIDE; RPT2 COILED COIL PEPTIDE; RPT4 COILED COIL PEPTIDE; RPT4 PROTEIN; RPT5 COILED COIL PEPTIDE; TEF1 PROTEIN; UNCLASSIFIED DRUG; ATP DEPENDENT 26S PROTEASE;

AMINO ACID SEQUENCE; ANTIFUNGAL ACTIVITY; ARTICLE; BIOTINYLATION; CELL COUNT; CELL GROWTH; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPLICATION ORIGIN; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFECT; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; FUNGAL GENE; FUNGUS GROWTH; GENE DOSAGE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GROWTH INHIBITION; GROWTH RATE; HYDROPHOBICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOLECULAR GENETICS; YEAST;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; YEASTS;

EID: 84947798607     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.10.144     Document Type: Article

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