The adaptor protein Myd88 is a key signaling molecule in the pathogenesis of irinotecan-induced intestinal mucositis

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Wong, Deysi V T ^a,b   Lima Júnior, Roberto C P ^a   Carvalho, Cibele B M ^c   Borges, Vanessa F ^d   Wanderley, Carlos W S ^a   Bem, Amanda X C ^a   Leite, Caio A V G ^a   Teixeira, Maraiza A ^a   Batista, Gabriela L P ^a   Silva, Rangel L ^d   Cunha, Thiago M ^d   Brito, Gerly A C ^c   Almeida, Paulo R C ^c   Cunha, Fernando Q ^d   Ribeiro, Ronaldo A ^a,b   Alexopoulou, Lena ^e  

^a School of Medicine University of Ceará   (Brazil)

^b Instituto do Cancer do Ceara   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; IRINOTECAN; MYELOID DIFFERENTIATION FACTOR 88; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; CAMPTOTHECIN; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL LOAD; CONTROLLED STUDY; DIARRHEA; ENTERITIS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSITIS; INTESTINE INJURY; MALE; MOUSE; MUCOSA INFLAMMATION; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SURVIVAL TIME; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; ENTEROPATHY; GENETICS; INTESTINE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BACTEREMIA; CAMPTOTHECIN; DIARRHEA; INTESTINAL DISEASES; INTESTINES; MICE; MICE, KNOCKOUT; MUCOSITIS; MYELOID DIFFERENTIATION FACTOR 88; PEROXIDASE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 9;

EID: 84947752917     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0139985     Document Type: Article

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