Attenuation of nitrogen mustard-induced pulmonary injury and fibrosis by anti-tumor necrosis factor-α antibody

Toxicological Sciences

Volumn 148, Issue 1, 2015, Pages 71-88

  Malaviya, Rama ^a   Sunil, Vasanthi R ^a   Venosa, Alessandro ^a   Verissimo, Vivianne L ^a   Cervelli, Jessica A ^a   Vayas, Kinal N ^a   Hall, LeRoy ^c   Laskin, Jeffrey D ^b   Laskin, Debra L ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Alveolar macrophages; Fibrosis; Lung injury; Vesicant

Indexed keywords

BRONCHOALVEOLAR LAVAGE PROTEIN; CHLORMETHINE; COLLAGEN; HEME OXYGENASE 1; PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; ALKYLATING AGENT; BIOLOGICAL MARKER; CHEMICAL WARFARE AGENT; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EDEMA; FIBRIN DEPOSITION; HISTOPATHOLOGY; LUNG; LUNG ALVEOLUS WALL; LUNG EMPHYSEMA; LUNG FIBROSIS; LUNG INJURY; MACROPHAGE; MALE; MONOCYTE; NITROGEN MUSTARD INDUCED PULMONARY FIBROSIS; NITROGEN MUSTARD INDUCED PULMONARY INJURY; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; CHEMISTRY; DISEASE COURSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY EMPHYSEMA; PULMONARY FIBROSIS; RESPIRATORY MUCOSA; WISTAR RAT;

ALKYLATING AGENTS; ANIMALS; ANTIBODIES, MONOCLONAL; BIOMARKERS; CHEMICAL WARFARE AGENTS; DISEASE PROGRESSION; IMMUNOGLOBULIN G; LUNG; MACROPHAGES; MALE; MECHLORETHAMINE; MICE; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS; PULMONARY EMPHYSEMA; PULMONARY FIBROSIS; RATS, WISTAR; RECOMBINANT PROTEINS; RESPIRATORY MUCOSA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84947732607     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv161     Document Type: Article

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