-
1
-
-
84896330378
-
Demystifying disease, democratizing health care
-
L. Hood, N. D. Price, Demystifying disease, democratizing health care. Sci. Transl. Med. 6, 225ed5 (2014)
-
(2014)
Sci. Transl. Med
, vol.6
, pp. 225ed5
-
-
Hood, L.1
Price, N.D.2
-
2
-
-
84900328733
-
Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy
-
A. Aytes, A. Mitrofanova, C. Lefebvre, M. J. Alvarez, M. Castillo-Martin, T. Zheng, J. A. Eastham, A. Gopalan, K. J. Pienta, M. M. Shen, A. Califano, C. Abate-Shen, Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy. Cancer Cell 25, 638-651 (2014)
-
(2014)
Cancer Cell
, vol.25
, pp. 638-651
-
-
Aytes, A.1
Mitrofanova, A.2
Lefebvre, C.3
Alvarez, M.J.4
Castillo-Martin, M.5
Zheng, T.6
Eastham, J.A.7
Gopalan, A.8
Pienta, K.J.9
Shen, M.M.10
Califano, A.11
Abate-Shen, C.12
-
3
-
-
80054689794
-
An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma
-
P. Sumazin, X. Yang, H.-S. Chiu, W.-J. Chung, A. Iyer, D. Llobet-Navas, P. Rajbhandari, M. Bansal, P. Guarnieri, J. Silva, A. Califano, An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell 147, 370-381 (2011)
-
(2011)
Cell
, vol.147
, pp. 370-381
-
-
Sumazin, P.1
Yang, X.2
Chiu, H.-S.3
Chung, W.-J.4
Iyer, A.5
Llobet-Navas, D.6
Rajbhandari, P.7
Bansal, M.8
Guarnieri, P.9
Silva, J.10
Califano, A.11
-
4
-
-
84915815121
-
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks
-
J. C. Chen, M. J. Alvarez, F. Talos, H. Dhruv, G. E. Rieckhof, A. Iyer, K. L. Diefes, K. Aldape, M. Berens, M. M. Shen, A. Califano, Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks. Cell 159, 402-414 (2014)
-
(2014)
Cell
, vol.159
, pp. 402-414
-
-
Chen, J.C.1
Alvarez, M.J.2
Talos, F.3
Dhruv, H.4
Rieckhof, G.E.5
Iyer, A.6
Diefes, K.L.7
Aldape, K.8
Berens, M.9
Shen, M.M.10
Califano, A.11
-
5
-
-
84899648957
-
Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment
-
M. Gustafsson, M. Edstrm, D. Gawel, C. E. Nestor, H. Wang, H. Zhang, F. Barrens, J. Tojo, I. Kockum, T. Olsson, J. Serra-Musach, N. Bonifaci, M. A. Pujana, J. Ernerudh, M. Benson, Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment. Genome Med. 6, 17 (2014)
-
(2014)
Genome Med
, vol.6
, pp. 17
-
-
Gustafsson, M.1
Edstrm, M.2
Gawel, D.3
Nestor, C.E.4
Wang, H.5
Zhang, H.6
Barrens, F.7
Tojo, J.8
Kockum, I.9
Olsson, T.10
Serra-Musach, J.11
Bonifaci, N.12
Pujana, M.A.13
Ernerudh, J.14
Benson, M.15
-
6
-
-
84874370461
-
T-helper 2 immunity is associated with reduced risk of myocardial infarction and stroke
-
D. Engelbertsen, L. Andersson, I. Ljungcrantz, M. Wigren, B. Hedblad, J. Nilsson, H. Bjrkbacka, T-helper 2 immunity is associated with reduced risk of myocardial infarction and stroke. Arterioscler. Thromb. Vasc. Biol. 33, 637-644 (2013)
-
(2013)
Arterioscler. Thromb. Vasc. Biol
, vol.33
, pp. 637-644
-
-
Engelbertsen, D.1
Andersson, L.2
Ljungcrantz, I.3
Wigren, M.4
Hedblad, B.5
Nilsson, J.6
Bjrkbacka, H.7
-
7
-
-
0032433127
-
The central role of CD4+ T cells in the antitumor immune response
-
K. Hung, R. Hayashi, A. Lafond-Walker, C. Lowenstein, D. Pardoll, H. Levitsky, The central role of CD4+ T cells in the antitumor immune response. J. Exp. Med. 188, 2357-2368 (1998)
-
(1998)
J. Exp. Med
, vol.188
, pp. 2357-2368
-
-
Hung, K.1
Hayashi, R.2
Lafond-Walker, A.3
Lowenstein, C.4
Pardoll, D.5
Levitsky, H.6
-
8
-
-
84867087508
-
A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation
-
X. Cheng, J. Wang, N. Xia, X.-X. Yan, T.-T. Tang, H. Chen, H.-J. Zhang, J. Liu, W. Kong, S. Sjberg, E. Folco, P. Libby, Y.-H. Liao, G.-P. Shi, A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. EMBO Mol. Med. 4, 1112-1125 (2012)
-
(2012)
EMBO Mol. Med
, vol.4
, pp. 1112-1125
-
-
Cheng, X.1
Wang, J.2
Xia, N.3
Yan, X.-X.4
Tang, T.-T.5
Chen, H.6
Zhang, H.-J.7
Liu, J.8
Kong, W.9
Sjberg, S.10
Folco, E.11
Libby, P.12
Liao, Y.-H.13
Shi, G.-P.14
-
9
-
-
84884910754
-
Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1
-
H. Zhang, C. E. Nestor, S. Zhao, A. Lentini, B. Bohle, M. Benson, H. Wang, Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1. J. Allergy Clin. Immunol. 132, 1005-1008 (2013)
-
(2013)
J. Allergy Clin. Immunol
, vol.132
, pp. 1005-1008
-
-
Zhang, H.1
Nestor, C.E.2
Zhao, S.3
Lentini, A.4
Bohle, B.5
Benson, M.6
Wang, H.7
-
10
-
-
84862198697
-
AnimalTFDB: A comprehensive animal transcription factor database
-
H.-M. Zhang, H. Chen, W. Liu, H. Liu, J. Gong, H. Wang, A.-Y. Guo, AnimalTFDB: A comprehensive animal transcription factor database. Nucleic Acids Res. 40, D144-D149 (2012)
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D144-D149
-
-
Zhang, H.-M.1
Chen, H.2
Liu, W.3
Liu, H.4
Gong, J.5
Wang, H.6
Guo, A.-Y.7
-
11
-
-
77950652940
-
Integrating multiple evidence sources to predict transcription factor binding in the human genome
-
J. Ernst, H. L. Plasterer, I. Simon, Z. Bar-Joseph, Integrating multiple evidence sources to predict transcription factor binding in the human genome. Genome Res. 20, 526-536 (2010)
-
(2011)
Genome Res
, vol.20
, pp. 526-536
-
-
Ernst, J.1
Plasterer, H.L.2
Simon, I.3
Bar-Joseph, Z.4
-
12
-
-
77950537175
-
Regularization paths for generalized linear models via coordinate descent
-
J. H. Friedman, T. Hastie, R. Tibshirani, Regularization paths for generalized linear models via coordinate descent. J. Stat. Softw. 33, 1-22 (2010)
-
(2011)
J. Stat. Softw
, vol.33
, pp. 1-22
-
-
Friedman, J.H.1
Hastie, T.2
Tibshirani, R.3
-
13
-
-
84871783406
-
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
-
A. Kanhere, A. Hertweck, U. Bhatia, M. R. Gkmen, E. Perucha, I. Jackson, G. M. Lord, R. G. Jenner, T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat. Commun. 3, 1268 (2012)
-
(2012)
Nat. Commun
, vol.3
, pp. 1268
-
-
Kanhere, A.1
Hertweck, A.2
Bhatia, U.3
Gkmen, M.R.4
Perucha, E.5
Jackson, I.6
Lord, G.M.7
Jenner, R.G.8
-
14
-
-
84892540269
-
A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy
-
S. Bruhn, Y. Fang, F. Barrens, M. Gustafsson, H. Zhang, A. Konstantinell, A. Krnke, B. Snnichsen, A. Bresnick, N. Dulyaninova, H. Wang, Y. Zhao, J. Klingelhfer, N. Ambartsumian, M. K. Beck, C. Nestor, E. Bona, Z. Xiang, M. Benson, A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy. Sci. Transl. Med. 6, 218ra4 (2014)
-
(2014)
Sci. Transl. Med
, vol.6
, pp. 218ra4
-
-
Bruhn, S.1
Fang, Y.2
Barrens, F.3
Gustafsson, M.4
Zhang, H.5
Konstantinell, A.6
Krnke, A.7
Snnichsen, B.8
Bresnick, A.9
Dulyaninova, N.10
Wang, H.11
Zhao, Y.12
Klingelhfer, J.13
Ambartsumian, N.14
Beck, M.K.15
Nestor, C.16
Bona, E.17
Xiang, Z.18
Benson, M.19
-
15
-
-
50149102578
-
Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event
-
J.-C. Corvol, D. Pelletier, R. G. Henry, S. J. Caillier, J. Wang, D. Pappas, S. Casazza, D. T. Okuda, S. L. Hauser, J. R. Oksenberg, S. E. Baranzini, Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event. Proc. Natl. Acad. Sci. U. S. A. 105, 11839-11844 (2008)
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 11839-11844
-
-
Corvol, J.-C.1
Pelletier, D.2
Henry, R.G.3
Caillier, S.J.4
Wang, J.5
Pappas, D.6
Casazza, S.7
Okuda, D.T.8
Hauser, S.L.9
Oksenberg, J.R.10
Baranzini, S.E.11
-
16
-
-
70349128065
-
Molecular profiling of CD3CD4+ T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways
-
M. Ravoet, C. Sibille, C. Gu, M. Libin, B. Haibe-Kains, C. Sotiriou, M. Goldman, F. Roufosse, K. Willard-Gallo, Molecular profiling of CD3CD4+ T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways. Blood 114, 2969-2983 (2009)
-
(2009)
Blood
, vol.114
, pp. 2969-2983
-
-
Ravoet, M.1
Sibille, C.2
Gu, C.3
Libin, M.4
Haibe-Kains, B.5
Sotiriou, C.6
Goldman, M.7
Roufosse, F.8
Willard-Gallo, K.9
-
17
-
-
22144489127
-
Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells
-
G. Grgn, T. A. W. Holderried, D. Zahrieh, D. Neuberg, J. G. Gribben, Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells. J. Clin. Invest. 115, 1797-1805 (2005)
-
(2005)
J. Clin. Invest
, vol.115
, pp. 1797-1805
-
-
Grgn, G.1
Holderried, T.A.W.2
Zahrieh, D.3
Neuberg, D.4
Gribben, J.G.5
-
18
-
-
65449155163
-
Gene expression profiling of ATL patients: Compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability
-
C. A. Pise-Masison, M. Radonovich, K. Dohoney, J. C. Morris, D. OMahony, M.-J. Lee, J. Trepel, T. A. Waldmann, J. E. Janik, J. N. Brady, Gene expression profiling of ATL patients: Compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability. Blood 113, 4016-4026 (2009)
-
(2009)
Blood
, vol.113
, pp. 4016-4026
-
-
Pise-Masison, C.A.1
Radonovich, M.2
Dohoney, K.3
Morris, J.C.4
OMahony, D.5
Lee, M.-J.6
Trepel, J.7
Waldmann, T.A.8
Janik, J.E.9
Brady, J.N.10
-
19
-
-
70449711157
-
Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts
-
R. Le Dieu, D. C. Taussig, A. G. Ramsay, R. Mitter, F. Miraki-Moud, R. Fatah, A. M. Lee, T. A. Lister, J. G. Gribben, Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts. Blood 114, 3909-3916 (2009)
-
(2009)
Blood
, vol.114
, pp. 3909-3916
-
-
Le Dieu, R.1
Taussig, D.C.2
Ramsay, A.G.3
Mitter, R.4
Miraki-Moud, F.5
Fatah, R.6
Lee, A.M.7
Lister, T.A.8
Gribben, J.G.9
-
20
-
-
84896736610
-
DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure
-
C. E. Nestor, F. Barrens, H. Wang, A. Lentini, H. Zhang, S. Bruhn, R. Jrnsten, M. A. Langston, G. Rogers, M. Gustafsson, M. Benson, DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure. PLOS Genet. 10, e1004059 (2014)
-
(2014)
PLOS Genet
, vol.10
, pp. e1004059
-
-
Nestor, C.E.1
Barrens, F.2
Wang, H.3
Lentini, A.4
Zhang, H.5
Bruhn, S.6
Jrnsten, R.7
Langston, M.A.8
Rogers, G.9
Gustafsson, M.10
Benson, M.11
-
21
-
-
80051684615
-
International multiple sclerosis genetics Consortium; Wellcome Trust Case Control Consortium 2, Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
-
S. Sawcer, G. Hellenthal, M. Pirinen, C. C. Spencer, N. A. Patsopoulos, L. Moutsianas, A. Dilthey, Z. Su, C. Freeman, S. E. Hunt, S. Edkins, E. Gray, D. R. Booth, S. C. Potter, A. Goris, G. Band, A. B. Oturai, A. Strange, J. Saarela, C. Bellenguez, B. Fontaine, M. Gillman, B. Hemmer, R. Gwilliam, F. Zipp, A. Jayakumar, R. Martin, S. Leslie, S. Hawkins, E. Giannoulatou, S. Dalfonso, H. Blackburn, F. Martinelli Boneschi, J. Liddle, H. F. Harbo, M. L. Perez, A. Spurkland, M. J. Waller, M. P. Mycko, M. Ricketts, M. Comabella, N. Hammond, I. Kockum, O. T. McCann, M. Ban, P. Whittaker, A. Kemppinen, P. Weston, C. Hawkins, S. Widaa, J. Zajicek, S. Dronov, N. Robertson, S. J. Bumpstead, L. F. Barcellos, R. Ravindrarajah, R. Abraham, L. Alfredsson, K. Ardlie, C. Aubin, A. Baker, K. Baker, S. E. Baranzini, L. Bergamaschi, R. Bergamaschi, A. Bernstein, A. Berthele, M. Boggild, J. P. Bradfield, D. Brassat, S. A. Broadley, D. Buck, H. Butzkueven, R. Capra, W. M. Carroll, P. Cavalla, E. G. Celius, S. Cepok, R. Chiavacci, F. Clerget-Darpoux, K. Clysters, G. Comi, M. Cossburn, I. Cournu-Rebeix, M. B. Cox, W. Cozen, B. A. Cree, A. H. Cross, D. Cusi, M. J. Daly, E. Davis, P. I. de Bakker, M. Debouverie, M. B. Dhooghe, K. Dixon, R. Dobosi, B. Dubois, D. Ellinghaus, I. Elovaara, F. Esposito, C. Fontenille, S. Foote, A. Franke, D. Galimberti, A. Ghezzi, J. Glessner, R. Gomez, O. Gout, C. Graham, S. F. Grant, F. R. Guerini, H. Hakonarson, P. Hall, A. Hamsten, H. P. Hartung, R. N. Heard, S. Heath, J. Hobart, M. Hoshi, C. Infante-Duarte, G. Ingram, W. Ingram, T. Islam, M. Jagodic, M. Kabesch, A. G. Kermode, T. J. Kilpatrick, C. Kim, N. Klopp, K. Koivisto, M. Larsson, M. Lathrop, J. S. Lechner-Scott, M. A. Leone, V. Lepp, U. Liljedahl, I. L. Bomfim, R. R. Lincoln, J. Link, J. Liu, A. R. Lorentzen, S. Lupoli, F. Macciardi, T. Mack, M. Marriott, V. Martinelli, D. Mason, J. L. McCauley, F. Mentch, I.-L. Mero, T. Mihalova, X. Montalban, J. Mottershead, K.-M. Myhr, P. Naldi, W. Ollier, A. Page, A. Palotie, J. Pelletier, L. Piccio, T. Pickersgill, F. Piehl, S. Pobywajlo, H. L. Quach, P. P. Ramsay, M. Reunanen, R. Reynolds, J. D. Rioux, M. Rodegher, S. Roesner, J. P. Rubio, I. M. Rckert, M. Salvetti, E. Salvi, A. Santaniello, C. A. Schaefer, S. Schreiber, C. Schulze, R. J. Scott, F. Sellebjerg, K. W. Selmaj, D. Sexton, L. Shen, B. Simms-Acuna, S. Skidmore, P. M. Sleiman, C. Smestad, P. S. SOrensen, H. B. SOndergaard, J. Stankovich, R. C. Strange, A. M. Sulonen, E. Sundqvist, A. C. Syvnen, F. Taddeo, B. Taylor, J. M. Blackwell, P. Tienari, E. Bramon, A. Tourbah, M. A. Brown, E. Tronczynska, J. P. Casas, N. Tubridy, A. Corvin, J. Vickery, J. Jankowski, P. Villoslada, H. S. Markus, K. Wang, C. G. Mathew, J. Wason, C. N. Palmer, H. E. Wichmann, R. Plomin, E. Willoughby, A. Rautanen, J. Winkelmann, M. Wittig, R. C. Trembath, J. Yaouanq, A. C. Viswanathan, H. Zhang, N. W. Wood, R. Zuvich, P. Deloukas, C. Langford, A. Duncanson, J. R. Oksenberg, M. A. Pericak-Vance, J. L. Haines, T. Olsson, J. Hillert, A. J. Ivinson, P. L. De Jager, L. Peltonen, G. J. Stewart, D. A. Hafler, S. L. Hauser, G. McVean, P. Donnelly, A. Compston; International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2, Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476, 214-219 (2011)
-
(2011)
Nature
, vol.476
, pp. 214-219
-
-
Sawcer, S.1
Hellenthal, G.2
Pirinen, M.3
Spencer, C.C.4
Patsopoulos, N.A.5
Moutsianas, L.6
Dilthey, A.7
Su, Z.8
Freeman, C.9
Hunt, S.E.10
Edkins, S.11
Gray, E.12
Booth, D.R.13
Potter, S.C.14
Goris, A.15
Band, G.16
Oturai, A.B.17
Strange, A.18
Saarela, J.19
Bellenguez, C.20
Fontaine, B.21
Gillman, M.22
Hemmer, B.23
Gwilliam, R.24
Zipp, F.25
Jayakumar, A.26
Martin, R.27
Leslie, S.28
Hawkins, S.29
Giannoulatou, E.30
Dalfonso, S.31
Blackburn, H.32
Martinelli Boneschi, F.33
Liddle, J.34
Harbo, H.F.35
Perez, M.L.36
Spurkland, A.37
Waller, M.J.38
Mycko, M.P.39
Ricketts, M.40
Comabella, M.41
Hammond, N.42
Kockum, I.43
McCann, O.T.44
Ban, M.45
Whittaker, P.46
Kemppinen, A.47
Weston, P.48
Hawkins, C.49
Widaa, S.50
Zajicek, J.51
Dronov, S.52
Robertson, N.53
Bumpstead, S.J.54
Barcellos, L.F.55
Ravindrarajah, R.56
Abraham, R.57
Alfredsson, L.58
Ardlie, K.59
Aubin, C.60
Baker, A.61
Baker, K.62
Baranzini, S.E.63
Bergamaschi, L.64
Bergamaschi, R.65
Bernstein, A.66
Berthele, A.67
Boggild, M.68
Bradfield, J.P.69
Brassat, D.70
Broadley, S.A.71
Buck, D.72
Butzkueven, H.73
Capra, R.74
Carroll, W.M.75
Cavalla, P.76
Celius, E.G.77
Cepok, S.78
Chiavacci, R.79
Clerget-Darpoux, F.80
Clysters, K.81
Comi, G.82
Cossburn, M.83
Cournu-Rebeix, I.84
Cox, M.B.85
Cozen, W.86
Cree, B.A.87
Cross, A.H.88
Cusi, D.89
Daly, M.J.90
Davis, E.91
De Bakker, P.I.92
Debouverie, M.93
Dhooghe, M.B.94
Dixon, K.95
Dobosi, R.96
Dubois, B.97
Ellinghaus, D.98
Elovaara, I.99
more..
-
22
-
-
84883037467
-
CD247 variants and single-nucleotide polymorphisms observed in systemic lupus erythematosus patients
-
T. Takeuchi, K. Suzuki, CD247 variants and single-nucleotide polymorphisms observed in systemic lupus erythematosus patients. Rheumatology 52, 1551-1555 (2013)
-
(2013)
Rheumatology
, vol.52
, pp. 1551-1555
-
-
Takeuchi, T.1
Suzuki, K.2
-
23
-
-
84875702300
-
Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy
-
M. J. H. Coenen, J. M. Hofstra, H. Debiec, H. C. Stanescu, A. J. Medlar, B. Stengel, A. Boland-Aug, J. M. Groothuismink, D. Bockenhauer, S. H. Powis, P. W. Mathieson, P. E. Brenchley, R. Kleta, J. F. M. Wetzels, P. Ronco, Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy. J. Am. Soc. Nephrol. 24, 677-683 (2013)
-
(2013)
J. Am. Soc. Nephrol
, vol.24
, pp. 677-683
-
-
Coenen, M.J.H.1
Hofstra, J.M.2
Debiec, H.3
Stanescu, H.C.4
Medlar, A.J.5
Stengel, B.6
Boland-Aug, A.7
Groothuismink, J.M.8
Bockenhauer, D.9
Powis, S.H.10
Mathieson, P.W.11
Brenchley, P.E.12
Kleta, R.13
Wetzels, J.F.M.14
Ronco, P.15
-
24
-
-
84908024712
-
Targeted omics and systems medicine: Personalising care
-
H. Zhang, M. Gustafsson, C. Nestor, K. F. Chung, M. Benson, Targeted omics and systems medicine: Personalising care. Lancet Respir. Med. 2, 785-787 (2014)
-
(2014)
Lancet Respir. Med
, vol.2
, pp. 785-787
-
-
Zhang, H.1
Gustafsson, M.2
Nestor, C.3
Chung, K.F.4
Benson, M.5
-
25
-
-
84862234311
-
Highly interconnected genes in disease-specific networks are enriched for disease-Associated polymorphisms
-
F. Barrens, S. Chavali, A. C. Alves, L. Coin, M.-R. Jarvelin, R. Jrnsten, M. A. Langston, A. Ramasamy, G. Rogers, H. Wang, M. Benson, Highly interconnected genes in disease-specific networks are enriched for disease-Associated polymorphisms. Genome Biol. 13, R46 (2012)
-
(2012)
Genome Biol
, vol.13
, pp. R46
-
-
Barrens, F.1
Chavali, S.2
Alves, A.C.3
Coin, L.4
Jarvelin, M.-R.5
Jrnsten, R.6
Langston, M.A.7
Ramasamy, A.8
Rogers, G.9
Wang, H.10
Benson, M.11
-
26
-
-
77951770756
-
BEDTools: A flexible suite of utilities for comparing genomic features
-
A. R. Quinlan, I. M. Hall, BEDTools: A flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841-842 (2010)
-
(2011)
Bioinformatics
, vol.26
, pp. 841-842
-
-
Quinlan, A.R.1
Hall, I.M.2
-
27
-
-
33646147811
-
MaSigPro: A method to identify significantly differential expression profiles in time-course microarray experiments
-
A. Conesa, M. J. Nueda, A. Ferrer, M. Taln, maSigPro: A method to identify significantly differential expression profiles in time-course microarray experiments. Bioinformatics 22, 1096-1102 (2006)
-
(2006)
Bioinformatics
, vol.22
, pp. 1096-1102
-
-
Conesa, A.1
Nueda, M.J.2
Ferrer, A.3
Taln, M.4
-
28
-
-
66349108078
-
Fewer permutations, more accurate P-values
-
T. A. Knijnenburg, L. F. A. Wessels, M. J. T. Reinders, I. Shmulevich, Fewer permutations, more accurate P-values. Bioinformatics 25, i161-i168 (2009)
-
(2009)
Bioinformatics
, vol.25
, pp. i161-i168
-
-
Knijnenburg, T.A.1
Wessels, L.F.A.2
Reinders, M.J.T.3
Shmulevich, I.4
-
29
-
-
71249086283
-
Increased IFN-g activity in seasonal allergic rhinitis is decreased by corticosteroid treatment
-
H. Wang, F. Barrens, S. Bruhn, R. Mobini, M. Benson, Increased IFN-g activity in seasonal allergic rhinitis is decreased by corticosteroid treatment. J. Allergy Clin. Immunol. 124, 1360-1362 (2009)
-
(2009)
J. Allergy Clin. Immunol
, vol.124
, pp. 1360-1362
-
-
Wang, H.1
Barrens, F.2
Bruhn, S.3
Mobini, R.4
Benson, M.5
-
30
-
-
33745376748
-
A networkbased analysis of the late-phase reaction of the skin
-
M. Benson, M. A. Langston, M. Adner, B. Andersson, A. Torinssson-Naluai, L. O. Cardell, A networkbased analysis of the late-phase reaction of the skin. J. Allergy Clin. Immunol. 118, 220-225 (2006)
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 220-225
-
-
Benson, M.1
Langston, M.A.2
Adner, M.3
Andersson, B.4
Torinssson-Naluai, A.5
Cardell, L.O.6
-
31
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
B. Langmead, S. L. Salzberg, Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357-359 (2012)
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
Salzberg, S.L.2
-
32
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS
-
Y. Zhang, T. Liu, C. A. Meyer, J. Eeckhoute, D. S. Johnson, B. E. Bernstein, C. Nusbaum, R. M. Myers, M. Brown, W. Li, X. S. Liu, Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008)
-
(2008)
Genome Biol
, vol.9
, pp. R137
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nusbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
Liu, X.S.11
-
33
-
-
84861023442
-
GWASdb: A database for human genetic variants identified by genome-wide association studies
-
M. J. Li, P. Wang, X. Liu, E. L. Lim, Z. Wang, M. Yeager, M. P. Wong, P. C. Sham, S. J. Chanock, J. Wang, GWASdb: A database for human genetic variants identified by genome-wide association studies. Nucleic Acids Res. 40, D1047-D1054 (2012)
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D1047-D1054
-
-
Li, M.J.1
Wang, P.2
Liu, X.3
Lim, E.L.4
Wang, Z.5
Yeager, M.6
Wong, M.P.7
Sham, P.C.8
Chanock, S.J.9
Wang, J.10
-
34
-
-
84884197513
-
An enhanced computational platform for investigating the roles of regulatory RNA and for identifying functional RNA motifs
-
T.-H. Chang, H.-Y. Huang, J. B.-K. Hsu, S.-L. Weng, J.-T. Horng, H.-D. Huang, An enhanced computational platform for investigating the roles of regulatory RNA and for identifying functional RNA motifs. BMC Bioinformatics 14, S4 (2013)
-
(2013)
BMC Bioinformatics
, vol.14
, pp. S4
-
-
Chang, T.-H.1
Huang, H.-Y.2
Hsu, J.B.-K.3
Weng, S.-L.4
Horng, J.-T.5
Huang, H.-D.6
-
35
-
-
84918777113
-
-
J. Qian, T. Hastie, J. Friedman, R. Tibshirani, N. Simon, Glmnet for Matlab; www. stanford. edu/~hastie/glmnet-matlab/.
-
Glmnet for Matlab
-
-
Qian, J.1
Hastie, T.2
Friedman, J.3
Tibshirani, R.4
Simon, N.5
-
36
-
-
33947305781
-
ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context
-
A. A. Margolin, I. Nemenman, K. Basso, C. Wiggins, G. Stolovitzky, R. Dalla Favera, A. Califano, ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinformatics 7, S7 (2006)
-
(2006)
BMC Bioinformatics
, vol.7
, pp. S7
-
-
Margolin, A.A.1
Nemenman, I.2
Basso, K.3
Wiggins, C.4
Stolovitzky, G.5
Dalla Favera, R.6
Califano, A.7
-
37
-
-
33747813561
-
The Inferelator: An algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo
-
R. Bonneau, D. J. Reiss, P. Shannon, M. Facciotti, L. Hood, N. S. Baliga, V. Thorsson, The Inferelator: An algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo. Genome Biol. 7, R36 (2006)
-
(2006)
Genome Biol
, vol.7
, pp. R36
-
-
Bonneau, R.1
Reiss, D.J.2
Shannon, P.3
Facciotti, M.4
Hood, L.5
Baliga, N.S.6
Thorsson, V.7
-
38
-
-
0024027325
-
C-terminal amidation of acylamino acids and peptides using a transpeptidation method catalyzed by carboxypeptidase y
-
I. V. Kapitannikov, A. A. Popov, E. V. Shimbarevich, L. D. Rumsh, V. K. Antonov, [C-terminal amidation of acylamino acids and peptides using a transpeptidation method catalyzed by carboxypeptidase Y]. Bioorg. Khim. 14, 797-801 (1988)
-
(1988)
Bioorg Khim
, vol.14
, pp. 797-801
-
-
Kapitannikov, I.V.1
Popov, A.A.2
Shimbarevich, E.V.3
Rumsh, L.D.4
Antonov, V.K.5
-
39
-
-
27644508196
-
Constructing and analyzing a large-scale gene-togene regulatory network Lasso-constrained inference and biological validation
-
M. Gustafsson, M. Hrnquist, A. Lombardi, Constructing and analyzing a large-scale gene-togene regulatory network Lasso-constrained inference and biological validation. IEEE/ACM Trans. Comput. Biol. Bioinform. 2, 254-261 (2005)
-
(2005)
IEEE/ACM Trans. Comput. Biol. Bioinform
, vol.2
, pp. 254-261
-
-
Gustafsson, M.1
Hrnquist, M.2
Lombardi, A.3
-
40
-
-
63849175334
-
Reverse engineering of gene networks with LASSO and nonlinear basis functions
-
M. Gustafsson, M. Hrnquist, J. Lundstrm, J. Bjrkegren, J. Tegnr, Reverse engineering of gene networks with LASSO and nonlinear basis functions. Ann. N. Y. Acad. Sci. 1158, 265-275 (2009)
-
(2009)
Ann. N. Y. Acad. Sci
, vol.1158
, pp. 265-275
-
-
Gustafsson, M.1
Hrnquist, M.2
Lundstrm, J.3
Bjrkegren, J.4
Tegnr, J.5
-
41
-
-
84876207916
-
Robust data-driven incorporation of prior knowledge into the inference of dynamic regulatory networks
-
A. Greenfield, C. Hafemeister, R. Bonneau, Robust data-driven incorporation of prior knowledge into the inference of dynamic regulatory networks. Bioinformatics 29, 1060-1067 (2013)
-
(2013)
Bioinformatics
, vol.29
, pp. 1060-1067
-
-
Greenfield, A.1
Hafemeister, C.2
Bonneau, R.3
-
42
-
-
84902461237
-
Functional association networks as priors for gene regulatory network inference
-
M. E. Studham, A. Tjrnberg, T. E. M. Nordling, S. Nelander, E. L. L. Sonnhammer, Functional association networks as priors for gene regulatory network inference. Bioinformatics 30, i130-i138 (2014)
-
(2014)
Bioinformatics
, vol.30
, pp. i130-i138
-
-
Studham, M.E.1
Tjrnberg, A.2
Nordling, T.E.M.3
Nelander, S.4
Sonnhammer, E.L.L.5
-
43
-
-
79955562657
-
Network modeling of the transcriptional effects of copy number aberrations in glioblastoma
-
R. Jrnsten, T. Abenius, T. Kling, L. Schmidt, E. Johansson, T. E. M. Nordling, B. Nordlander, C. Sander, P. Gennemark, K. Funa, B. Nilsson, L. Lindahl, S. Nelander, Network modeling of the transcriptional effects of copy number aberrations in glioblastoma. Mol. Syst. Biol. 7, 486 (2011)
-
(2011)
Mol. Syst. Biol
, vol.7
, pp. 486
-
-
Jrnsten, R.1
Abenius, T.2
Kling, T.3
Schmidt, L.4
Johansson, E.5
Nordling, T.E.M.6
Nordlander, B.7
Sander, C.8
Gennemark, P.9
Funa, K.10
Nilsson, B.11
Lindahl, L.12
Nelander, S.13
-
44
-
-
84887058596
-
International Multiple Sclerosis Genetics Consortium (IMSGC), Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
-
Wellcome Trust Case Control Consortium 2 (WTCCC2) International IBD Genetics Consortium (IIBDGC)
-
A. H. Beecham, N. A. Patsopoulos, D. K. Xifara, M. F. Davis, A. Kemppinen, C. Cotsapas, T. S. Shah, C. Spencer, D. Booth, A. Goris, A. Oturai, J. Saarela, B. Fontaine, B. Hemmer, C. Martin, F. Zipp, S. DAlfonso, F. Martinelli-Boneschi, B. Taylor, H. F. Harbo, I. Kockum, J. Hillert, T. Olsson, M. Ban, J. R. Oksenberg, R. Hintzen, L. F. Barcellos; Wellcome Trust Case Control Consortium 2 (WTCCC2), International IBD Genetics Consortium (IIBDGC), C. Agliardi, L. Alfredsson, M. Alizadeh, C. Anderson, R. Andrews, H. B. Sndergaard, A. Baker, G. Band, S. E. Baranzini, N. Barizzone, J. Barrett, C. Bellenguez, L. Bergamaschi, L. Bernardinelli, A. Berthele, V. Biberacher, T. M. C. Binder, H. Blackburn, I. L. Bomfim, P. Brambilla, S. Broadley, B. Brochet, L. Brundin, D. Buck, H. Butzkueven, S. J. Caillier, W. Camu, W. Carpentier, P. Cavalla, E. G. Celius, I. Coman, G. Comi, L. Corrado, L. Cosemans, I. Cournu-Rebeix, B. A. C. Cree, D. Cusi, V. Damotte, G. Defer, S. R. Delgado, P. Deloukas, A. di Sapio, A. T. Dilthey, P. Donnelly, B. Dubois, M. Duddy, S. Edkins, I. Elovaara, F. Esposito, N. Evangelou, B. Fiddes, J. Field, A. Franke, C. Freeman, I. Y. Frohlich, D. Galimberti, C. Gieger, P.-A. Gourraud, C. Graetz, A. Graham, V. Grummel, C. Guaschino, A. Hadjixenofontos, H. Hakonarson, C. Halfpenny, G. Hall, P. Hall, A. Hamsten, J. Harley, T. Harrower, C. Hawkins, G. Hellenthal, C. Hillier, J. Hobart, M. Hoshi, S. E. Hunt, M. Jagodic, I. Jeli, A. Jochim, B. Kendall, A. Kermode, T. Kilpatrick, K. Koivisto, I. Konidari, T. Korn, H. Kronsbein, C. Langford, M. Larsson, M. Lathrop, C. Lebrun-Frenay, J. Lechner-Scott, M. H. Lee, M. A. Leone, V. Lepp, G. Liberatore, B. A. Lie, C. M. Lill, M. Lindn, J. Link, F. Luessi, J. Lycke, F. Macciardi, S. Mnnist, C. P. Manrique, R. Martin, V. Martinelli, D. Mason, G. Mazibrada, C. McCabe, I.-L. Mero, J. Mescheriakova, L. Moutsianas, K.-M. Myhr, G. Nagels, R. Nicholas, P. Nilsson, F. Piehl, M. Pirinen, S. E. Price, H. Quach, M. Reunanen, W. Robberecht, N. P. Robertson, M. Rodegher, D. Rog, M. Salvetti, N. C. Schnetz-Boutaud, F. Sellebjerg, R. C. Selter, C. Schaefer, S. Shaunak, L. Shen, S. Shields, V. Siffrin, M. Slee, P. S. Sorensen, M. Sorosina, M. Sospedra, A. Spurkland, A. Strange, E. Sundqvist, V. Thijs, J. Thorpe, A. Ticca, P. Tienari, C. van Duijn, E. M. Visser, S. Vucic, H. Westerlind, J. S. Wiley, A. Wilkins, J. F. Wilson, J. Winkelmann, J. Zajicek, E. Zindler, J. L. Haines, M. A. Pericak-Vance, A. J. Ivinson, G. Stewart, D. Hafler, S. L. Hauser, A. Compston, G. McVean, P. De Jager, S. J. Sawcer, J. L. McCauley; International Multiple Sclerosis Genetics Consortium (IMSGC), Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat. Genet. 45, 1353-1360 (2013)
-
(2013)
Nat. Genet
, vol.45
, pp. 1353-1360
-
-
Beecham, A.H.1
Patsopoulos, N.A.2
Xifara, D.K.3
Davis, M.F.4
Kemppinen, A.5
Cotsapas, C.6
Shah, T.S.7
Spencer, C.8
Booth, D.9
Goris, A.10
Oturai, A.11
Saarela, J.12
Fontaine, B.13
Hemmer, B.14
Martin, C.15
Zipp, F.16
DAlfonso, S.17
Martinelli-Boneschi, F.18
Taylor, B.19
Harbo, H.F.20
Kockum, I.21
Hillert, J.22
Olsson, T.23
Ban, M.24
Oksenberg, J.R.25
Hintzen, R.26
Barcellos, L.F.27
Agliardi, C.28
Alfredsson, L.29
Alizadeh, M.30
Anderson, C.31
Andrews, R.32
Sndergaard, H.B.33
Baker, A.34
Band, G.35
Baranzini, S.E.36
Barizzone, N.37
Barrett, J.38
Bellenguez, C.39
Bergamaschi, L.40
Bernardinelli, L.41
Berthele, A.42
Biberacher, V.43
Binder, T.M.C.44
Blackburn, H.45
Bomfim, I.L.46
Brambilla, P.47
Broadley, S.48
Brochet, B.49
Brundin, L.50
Buck, D.51
Butzkueven, H.52
Caillier, S.J.53
Camu, W.54
Carpentier, W.55
Cavalla, P.56
Celius, E.G.57
Coman, I.58
Comi, G.59
Corrado, L.60
Cosemans, L.61
Cournu-Rebeix, I.62
Cree, B.A.C.63
Cusi, D.64
Damotte, V.65
Defer, G.66
Delgado, S.R.67
Deloukas, P.68
Di Sapio, A.69
Dilthey, A.T.70
Donnelly, P.71
Dubois, B.72
Duddy, M.73
Edkins, S.74
Elovaara, I.75
Esposito, F.76
Evangelou, N.77
Fiddes, B.78
Field, J.79
Franke, A.80
Freeman, C.81
Frohlich, I.Y.82
Galimberti, D.83
Gieger, C.84
Gourraud, P.-A.85
Graetz, C.86
Graham, A.87
Grummel, V.88
Guaschino, C.89
Hadjixenofontos, A.90
Hakonarson, H.91
Halfpenny, C.92
Hall, G.93
Hall, P.94
Hamsten, A.95
Harley, J.96
Harrower, T.97
Hawkins, C.98
Hellenthal, G.99
more..
-
45
-
-
20144387016
-
Multiple sclerosis severity score: Using disability and disease duration to rate disease severity
-
R. H. Roxburgh, S. R. Seaman, T. Masterman, A. E. Hensiek, S. J. Sawcer, S. Vukusic, I. Achiti, C. Confavreux, M. Coustans, E. le Page, G. Edan, G. V. McDonnell, S. A. Hawkins, M. Trojano, M. Liguori, E. Cocco, M. G. Marrosu, F. Tesser, M. Leone, A. Weber, F. Zipp, B. Miterski, J. T. Epplen, A. Oturai, P. S. SOrensen, E. G. Celius, N. T. Lara, X. Montalban, P. Villoslada, A. M. Silva, M. Marta, I. Leite, B. Dubois, J. P. Rubio, H. Butzkueven, T. Kilpatrick, M. P. Mycko, K. W. Selmaj, M. E. Rio, M. J. S, G. Salemi, G. Savettieri, J. Hillert, D. A. S. Compston, Multiple sclerosis severity score: Using disability and disease duration to rate disease severity. Neurology 64, 1144-1151 (2005)
-
(2005)
Neurology
, vol.64
, pp. 1144-1151
-
-
Roxburgh, R.H.1
Seaman, S.R.2
Masterman, T.3
Hensiek, A.E.4
Sawcer, S.J.5
Vukusic, S.6
Achiti, I.7
Confavreux, C.8
Coustans, M.9
Le Page, E.10
Edan, G.11
McDonnell, G.V.12
Hawkins, S.A.13
Trojano, M.14
Liguori, M.15
Cocco, E.16
Marrosu, M.G.17
Tesser, F.18
Leone, M.19
Weber, A.20
Zipp, F.21
Miterski, B.22
Epplen, J.T.23
Oturai, A.24
SOrensen, P.S.25
Celius, E.G.26
Lara, N.T.27
Montalban, X.28
Villoslada, P.29
Silva, A.M.30
Marta, M.31
Leite, I.32
Dubois, B.33
Rubio, J.P.34
Butzkueven, H.35
Kilpatrick, T.36
Mycko, M.P.37
Selmaj, K.W.38
Rio, M.E.39
Salemi, G.40
Savettieri, G.41
Hillert, J.42
Compston, D.A.S.43
more..
-
46
-
-
84870397179
-
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and longrange gene regulation
-
Y. Chen, D. L. Bates, R. Dey, P.-H. Chen, A. C. D. Machado, I. A. Laird-Offringa, R. Rohs, L. Chen, DNA binding by GATA transcription factor suggests mechanisms of DNA looping and longrange gene regulation. Cell Rep. 2, 1197-1206 (2012)
-
(2012)
Cell Rep
, vol.2
, pp. 1197-1206
-
-
Chen, Y.1
Bates, D.L.2
Dey, R.3
Chen, P.-H.4
Machado, A.C.D.5
Laird-Offringa, I.A.6
Rohs, R.7
Chen, L.8
-
47
-
-
84891751965
-
RSNPBase: A database for curated regulatory SNPs
-
L. Guo, Y. Du, S. Chang, K. Zhang, J. Wang, rSNPBase: A database for curated regulatory SNPs. Nucleic Acids Res. 42, D1033-D1039 (2014)
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D1033-D1039
-
-
Guo, L.1
Du, Y.2
Chang, S.3
Zhang, K.4
Wang, J.5
|