Increased IFN-γ activity in seasonal allergic rhinitis is decreased by corticosteroid treatment

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 6, 2009, Pages 1360-1362

  Wang, Hui ^a   Barrenäs, Fredrik ^a   Bruhn, Sören ^a   Mobini, Reza ^a   Benson, Mikael ^a  

^a QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HYDROCORTISONE;

CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; GENE EXPRESSION PROFILING; HAY FEVER; HUMAN; HUMAN CELL; LETTER; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADRENAL CORTEX HORMONES; HUMANS; INTERFERON-GAMMA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RHINITIS, ALLERGIC, SEASONAL;

EID: 71249086283     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.09.037     Document Type: Letter

References (9)

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2. Woodfolk J.A. T-cell responses to allergens. J Allergy Clin Immunol 119 (2007) 280-294
3. Benson M., Strannegård I.L., Strannegård O., and Wennergren G. Topical steroid treatment of allergic rhinitis decreases nasal fluid TH2 cytokines, eosinophils, eosinophil cationic protein, and IgE but has no significant effect on IFN-gamma, IL-1beta, TNF-alpha, or neutrophils. J Allergy Clin Immunol 106 (2000) 307-312
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7. Sugimoto T., Ishikawa Y., Yoshimoto T., Hayashi N., Fujimoto J., and Nakanishi K. Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse. J Exp Med 199 (2004) 535-545
8. Devadas S., Das J., Liu C., Zhang L., Roberts A.I., Pan Z., et al. Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells. Immunity 25 (2006) 237-247
9. Benson M., Carlsson L., Adner M., Jernås M., Rudemo M., Sjögren A., et al. Gene profiling reveals increased expression of uteroglobin and other anti-inflammatory genes in glucocorticoid-treated nasal polyps. J Allergy Clin Immunol 113 (2004) 1137-1143