-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E. & Forman, D. Global cancer statistics. CA Cancer J Clin 61, 69-90 (2011).
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
77951755278
-
Pancreatic cancer
-
Hidalgo, M. Pancreatic cancer. N Engl J Med 362, 1605-1617 (2010).
-
(2010)
N Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
3
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2013. CA Cancer J Clin 63, 11-30 (2013).
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
4
-
-
84915813644
-
Pancreatic adenocarcinoma
-
Ryan, D. P., Hong, T. S. & Bardeesy, N. Pancreatic adenocarcinoma. N Engl J Med 371, 1039-1049 (2014).
-
(2014)
N Engl J Med
, vol.371
, pp. 1039-1049
-
-
Ryan, D.P.1
Hong, T.S.2
Bardeesy, N.3
-
5
-
-
34247197621
-
Chronic pancreatitis: Challenges and advances in pathogenesis, genetics, diagnosis, and therapy
-
Witt, H., Apte, M. V., Keim, V. & Wilson, J. S. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology 132, 1557-1573 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 1557-1573
-
-
Witt, H.1
Apte, M.V.2
Keim, V.3
Wilson, J.S.4
-
6
-
-
84876788888
-
Models of acute and chronic pancreatitis
-
Lerch, M. M. & Gorelick, F. S. Models of acute and chronic pancreatitis. Gastroenterology 144, 1180-1193 (2013).
-
(2013)
Gastroenterology
, vol.144
, pp. 1180-1193
-
-
Lerch, M.M.1
Gorelick, F.S.2
-
7
-
-
70349678580
-
New insights into alcoholic pancreatitis and pancreatic cancer
-
Apte, M., Pirola, R. & Wilson, J. New insights into alcoholic pancreatitis and pancreatic cancer. J Gastroenterol Hepatol 24, Suppl 3, S51-S56 (2009).
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. S51-S56
-
-
Apte, M.1
Pirola, R.2
Wilson, J.3
-
8
-
-
84864832834
-
The role of stroma in pancreatic cancer: Diagnostic and therapeutic implications
-
Erkan, M. et al. The role of stroma in pancreatic cancer: diagnostic and therapeutic implications. Nat Rev Gastroenterol Hepatol 9, 454-467 (2012).
-
(2012)
Nat Rev Gastroenterol Hepatol
, vol.9
, pp. 454-467
-
-
Erkan, M.1
-
9
-
-
78650895035
-
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
-
Zhao, B. et al. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev 25, 51-63 (2011).
-
(2011)
Genes Dev
, vol.25
, pp. 51-63
-
-
Zhao, B.1
-
10
-
-
84876943442
-
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the nonreceptor type protein tyrosine phosphatase 14
-
Huang, J. M. et al. YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the nonreceptor type protein tyrosine phosphatase 14. Oncogene 32, 2220-2229 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 2220-2229
-
-
Huang, J.M.1
-
11
-
-
78049451932
-
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
-
Cai, J., Zhang, N., Zheng, Y., De Wilde, R. F., Maitra, A. & Pan, D. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev 24, 2383-2388 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 2383-2388
-
-
Cai, J.1
Zhang, N.2
Zheng, Y.3
De Wilde, R.F.4
Maitra, A.5
Pan, D.6
-
12
-
-
77953040994
-
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
-
Lian, I. et al. The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev 24, 1106-1118 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 1106-1118
-
-
Lian, I.1
-
13
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi, M. et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147, 759-772 (2011).
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
-
14
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
-
Zhao, B., Li, L., Lei, Q. & Guan, K. L. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 24, 862-874 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
15
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao, Y., Chun, A., Cheung, K., Rashidi, B. & Yang, X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 283, 5496-5509 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
16
-
-
0037249343
-
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
-
Basu, S., Totty, N. F., Irwin, M. S., Sudol, M. & Downward, J. Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell 11, 11-23 (2003).
-
(2003)
Mol Cell
, vol.11
, pp. 11-23
-
-
Basu, S.1
Totty, N.F.2
Irwin, M.S.3
Sudol, M.4
Downward, J.5
-
17
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao, B. et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21, 2747-2761 (2007).
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
-
18
-
-
79953010044
-
Angiomotin-like proteins associate with and negatively regulate YAP1
-
Wang, W., Huang, J. & Chen, J. Angiomotin-like proteins associate with and negatively regulate YAP1. J Biol Chem 286, 4364-4370 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 4364-4370
-
-
Wang, W.1
Huang, J.2
Chen, J.3
-
19
-
-
79953223677
-
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
-
Chan, S. W., Lim, C. J., Chong, Y. F., Pobbati, A. V., Huang, C. & Hong, W. Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem 286, 7018-7026 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 7018-7026
-
-
Chan, S.W.1
Lim, C.J.2
Chong, Y.F.3
Pobbati, A.V.4
Huang, C.5
Hong, W.6
-
20
-
-
84874767303
-
PTPN14 interacts with and negatively regulates the oncogenic function of YAP
-
Liu, X. et al. PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene 32, 1266-1273 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 1266-1273
-
-
Liu, X.1
-
21
-
-
84876184181
-
The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity
-
Michaloglou, C. et al. The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS One 8, e61916 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e61916
-
-
Michaloglou, C.1
-
22
-
-
84906539718
-
PTPN14 forms complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function
-
Wilson, K. E., Li, Y. W., Yang, N., Shen, H., Orillion, A. R. & Zhang, J. PTPN14 forms complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function. J Biol Chem 289, 23693-23700 (2014).
-
(2014)
J Biol Chem
, vol.289
, pp. 23693-23700
-
-
Wilson, K.E.1
Li, Y.W.2
Yang, N.3
Shen, H.4
Orillion, A.R.5
Zhang, J.6
-
23
-
-
84857993243
-
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation
-
Poernbacher, I., Baumgartner, R., Marada, S. K., Edwards, K. & Stocker, H. Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation. Curr Biol 22, 389-396 (2012).
-
(2012)
Curr Biol
, vol.22
, pp. 389-396
-
-
Poernbacher, I.1
Baumgartner, R.2
Marada, S.K.3
Edwards, K.4
Stocker, H.5
-
24
-
-
0033617369
-
Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells
-
Ogata, M. et al. Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells. J Biol Chem 274, 12905-12909 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 12905-12909
-
-
Ogata, M.1
-
25
-
-
34748870853
-
The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development
-
Wyatt, L., Wadham, C., Crocker, L. A., Lardelli, M. & Khew-Goodall, Y. The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development. J Cell Biol 178, 1223-1235 (2007).
-
(2007)
J Cell Biol
, vol.178
, pp. 1223-1235
-
-
Wyatt, L.1
Wadham, C.2
Crocker, L.A.3
Lardelli, M.4
Khew-Goodall, Y.5
-
26
-
-
0038308412
-
The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin
-
Wadham, C., Gamble, J. R., Vadas, M. A. & Khew-Goodall, Y. The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. Mol Biol Cell 14, 2520-2529 (2003).
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2520-2529
-
-
Wadham, C.1
Gamble, J.R.2
Vadas, M.A.3
Khew-Goodall, Y.4
-
27
-
-
58149378342
-
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
-
Inada, A. et al. Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci USA 105, 19915-19919 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19915-19919
-
-
Inada, A.1
-
28
-
-
0037931407
-
Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy
-
Hayashi, K. Y., Tamaki, H., Handa, K., Takahashi, T., Kakita, A. & Yamashina, S. Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy. Arch Histol Cytol 66, 163-174 (2003).
-
(2003)
Arch Histol Cytol
, vol.66
, pp. 163-174
-
-
Hayashi, K.Y.1
Tamaki, H.2
Handa, K.3
Takahashi, T.4
Kakita, A.5
Yamashina, S.6
-
29
-
-
38749108893
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu, X. et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132, 197-207 (2008).
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
-
30
-
-
0038795203
-
Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin
-
Nagasao, J., Yoshioka, K., Amasaki, H. & Mutoh, K. Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin. Ann Anat 185, 211-216 (2003).
-
(2003)
Ann Anat
, vol.185
, pp. 211-216
-
-
Nagasao, J.1
Yoshioka, K.2
Amasaki, H.3
Mutoh, K.4
-
31
-
-
0026747671
-
The importance of the centroacinar region in cerulein-induced mouse pancreatic growth
-
Gasslander, T., Ihse, I. & Smeds, S. The importance of the centroacinar region in cerulein-induced mouse pancreatic growth. Scand J Gastroenterol 27, 564-570 (1992).
-
(1992)
Scand J Gastroenterol
, vol.27
, pp. 564-570
-
-
Gasslander, T.1
Ihse, I.2
Smeds, S.3
-
32
-
-
80053603426
-
Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice
-
1462 e1451-1456
-
Criscimanna, A. et al. Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice. Gastroenterology 141, 1451-1462, 1462 e1451-1456 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 1451-1462
-
-
Criscimanna, A.1
-
33
-
-
33646879441
-
Timing and expression pattern of carbonic anhydrase II in pancreas
-
Inada, A., Nienaber, C., Fonseca, S. & Bonner-Weir, S. Timing and expression pattern of carbonic anhydrase II in pancreas. Dev Dyn 235, 1571-1577 (2006).
-
(2006)
Dev Dyn
, vol.235
, pp. 1571-1577
-
-
Inada, A.1
Nienaber, C.2
Fonseca, S.3
Bonner-Weir, S.4
-
34
-
-
84055193971
-
Pancreatic ductal cells in development, regeneration, and neoplasia
-
Reichert, M. & Rustgi, A. K. Pancreatic ductal cells in development, regeneration, and neoplasia. J Clin Invest 121, 4572-4578 (2011).
-
(2011)
J Clin Invest
, vol.121
, pp. 4572-4578
-
-
Reichert, M.1
Rustgi, A.K.2
-
35
-
-
0027535021
-
Isolation culture, and characterization of human pancreatic duct cells
-
Trautmann, B., Schlitt, H. J., Hahn, E. G. & Lohr, M. Isolation, culture, and characterization of human pancreatic duct cells. Pancreas 8, 248-254 (1993).
-
(1993)
Pancreas
, vol.8
, pp. 248-254
-
-
Trautmann, B.1
Schlitt, H.J.2
Hahn, E.G.3
Lohr, M.4
-
36
-
-
33645217472
-
Tenascin C and annexin II expression in the process of pancreatic carcinogenesis
-
Esposito, I. et al. Tenascin C and annexin II expression in the process of pancreatic carcinogenesis. J Pathol 208, 673-685 (2006).
-
(2006)
J Pathol
, vol.208
, pp. 673-685
-
-
Esposito, I.1
-
37
-
-
0033887693
-
Progression model for pancreatic cancer
-
Hruban, R. H., Goggins, M., Parsons, J. & Kern, S. E. Progression model for pancreatic cancer. Clin Cancer Res 6, 2969-2972 (2000).
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2969-2972
-
-
Hruban, R.H.1
Goggins, M.2
Parsons, J.3
Kern, S.E.4
-
38
-
-
17144364694
-
Precursors to invasive pancreatic cancer
-
Maitra, A., Fukushima, N., Takaori, K. & Hruban, R. H. Precursors to invasive pancreatic cancer. Adv Anat Pathol 12, 81-91 (2005).
-
(2005)
Adv Anat Pathol
, vol.12
, pp. 81-91
-
-
Maitra, A.1
Fukushima, N.2
Takaori, K.3
Hruban, R.H.4
-
39
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani, S. R. et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4, 437-450 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
-
40
-
-
33748098707
-
Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice
-
Lugea, A., Nan, L., French, S. W., Bezerra, J. A., Gukovskaya, A. S. & Pandol, S. J. Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice. Gastroenterology 131, 885-899 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 885-899
-
-
Lugea, A.1
Nan, L.2
French, S.W.3
Bezerra, J.A.4
Gukovskaya, A.S.5
Pandol, S.J.6
-
41
-
-
84929347258
-
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis
-
Xue, J. et al. Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun 6, 7158 (2015).
-
(2015)
Nat Commun
, vol.6
, pp. 7158
-
-
Xue, J.1
-
42
-
-
84907305877
-
Genetic inhibition of protein kinase Cepsilon attenuates necrosis in experimental pancreatitis
-
Liu, Y. et al. Genetic inhibition of protein kinase Cepsilon attenuates necrosis in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol 307, G550-563 (2014).
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.307
, pp. G550-G563
-
-
Liu, Y.1
-
43
-
-
76249094159
-
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
-
Rovira, M., Scott, S. G., Liss, A. S., Jensen, J., Thayer, S. P. & Leach, S. D. Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas. Proc Natl Acad Sci USA 107, 75-80 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 75-80
-
-
Rovira, M.1
Scott, S.G.2
Liss, A.S.3
Jensen, J.4
Thayer, S.P.5
Leach, S.D.6
-
44
-
-
78651228289
-
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
-
Furuyama, K. et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 43, 34-41 (2011).
-
(2011)
Nat Genet
, vol.43
, pp. 34-41
-
-
Furuyama, K.1
-
45
-
-
79951539242
-
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
-
Kopp, J. L. et al. Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development 138, 653-665 (2011).
-
(2011)
Development
, vol.138
, pp. 653-665
-
-
Kopp, J.L.1
-
46
-
-
84870803922
-
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma
-
Kopp, J. L. et al. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell 22, 737-750 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 737-750
-
-
Kopp, J.L.1
-
47
-
-
84861221146
-
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
-
Manfroid, I. et al. Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Dev Biol 366, 268-278 (2012).
-
(2012)
Dev Biol
, vol.366
, pp. 268-278
-
-
Manfroid, I.1
-
48
-
-
84894041714
-
SOX9: A useful marker for pancreatic ductal lineage of pancreatic neoplasms
-
Shroff, S. et al. SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms. Hum Pathol 45, 456-463 (2014).
-
(2014)
Hum Pathol
, vol.45
, pp. 456-463
-
-
Shroff, S.1
-
49
-
-
84905459985
-
Hippo Coactivator YAP1 Upregulates SOX9 and Endows Esophageal Cancer Cells with Stem-like Properties
-
Song, S. et al. Hippo Coactivator YAP1 Upregulates SOX9 and Endows Esophageal Cancer Cells with Stem-like Properties. Cancer Res 74, 4170-4182 (2014).
-
(2014)
Cancer Res
, vol.74
, pp. 4170-4182
-
-
Song, S.1
-
50
-
-
2342510386
-
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor, Y., Brown, J., Martinez, O. I. & Melton, D. A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41-46 (2004).
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
51
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to betacells
-
Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. & Melton, D. A. In vivo reprogramming of adult pancreatic exocrine cells to betacells. Nature 455, 627-632 (2008).
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
52
-
-
66349132211
-
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis
-
Sangiorgi, E. & Capecchi, M. R. Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis. Proc Natl Acad Sci USA 106, 7101-7106 (2009).
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7101-7106
-
-
Sangiorgi, E.1
Capecchi, M.R.2
-
53
-
-
84878282156
-
Hippo signaling regulates differentiation and maintenance in the exocrine pancreas
-
1553 e1541
-
Gao, T. et al. Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology 144, 1543-1553, 1553 e1541 (2013).
-
(2013)
Gastroenterology
, vol.144
, pp. 1543-1553
-
-
Gao, T.1
-
54
-
-
84871862870
-
Hippo signaling regulates pancreas development through inactivation of Yap
-
George, N. M., Day, C. E., Boerner, B. P., Johnson, R. L. & Sarvetnick, N. E. Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol 32, 5116-5128 (2012).
-
(2012)
Mol Cell Biol
, vol.32
, pp. 5116-5128
-
-
George, N.M.1
Day, C.E.2
Boerner, B.P.3
Johnson, R.L.4
Sarvetnick, N.E.5
-
55
-
-
84923333865
-
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of beta-Catenin and Yap by PKCzeta
-
Llado, V. et al. Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of beta-Catenin and Yap by PKCzeta. Cell Rep 10, 740-754 (2015).
-
(2015)
Cell Rep
, vol.10
, pp. 740-754
-
-
Llado, V.1
-
56
-
-
17144404527
-
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
-
Bachem, M. G. et al. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 128, 907-921 (2005).
-
(2005)
Gastroenterology
, vol.128
, pp. 907-921
-
-
Bachem, M.G.1
-
57
-
-
83755195660
-
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
-
Zhou, D. et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci USA 108, E1312-1320 (2011).
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. E1312-E1320
-
-
Zhou, D.1
-
58
-
-
85018698979
-
Dual role of YAP and TAZ in renewal of the intestinal epithelium
-
Imajo, M., Ebisuya, M. & Nishida, E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol 17, 7-19 (2015).
-
(2015)
Nat Cell Biol
, vol.17
, pp. 7-19
-
-
Imajo, M.1
Ebisuya, M.2
Nishida, E.3
-
59
-
-
36549074631
-
YAP1 increases organ size and expands undifferentiated progenitor cells
-
Camargo, F. D. et al. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17, 2054-2060 (2007).
-
(2007)
Curr Biol
, vol.17
, pp. 2054-2060
-
-
Camargo, F.D.1
-
60
-
-
84904875885
-
The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors
-
Mahoney, J. E., Mori, M., Szymaniak, A. D., Varelas, X. & Cardoso, W. V. The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. Dev Cell 30, 137-150 (2014).
-
(2014)
Dev Cell
, vol.30
, pp. 137-150
-
-
Mahoney, J.E.1
Mori, M.2
Szymaniak, A.D.3
Varelas, X.4
Cardoso, W.V.5
-
61
-
-
84929948623
-
Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung
-
Lange, A. W., Sridharan, A., Xu, Y., Stripp, B. R., Perl, A. K. & Whitsett, J. A. Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung. J Mol Cell Biol 7, 35-47 (2015).
-
(2015)
J Mol Cell Biol
, vol.7
, pp. 35-47
-
-
Lange, A.W.1
Sridharan, A.2
Xu, Y.3
Stripp, B.R.4
Perl, A.K.5
Whitsett, J.A.6
-
62
-
-
84902081616
-
Hippo pathway activity influences liver cell fate
-
Yimlamai, D. et al. Hippo pathway activity influences liver cell fate. Cell 157, 1324-1338 (2014).
-
(2014)
Cell
, vol.157
, pp. 1324-1338
-
-
Yimlamai, D.1
-
63
-
-
84878600591
-
Yap controls stem/progenitor cell proliferation in the mouse postnatal epidermis
-
Beverdam, A., Claxton, C., Zhang, X., James, G., Harvey, K. F. & Key, B. Yap controls stem/progenitor cell proliferation in the mouse postnatal epidermis. J Invest Dermatol 133, 1497-1505 (2013).
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1497-1505
-
-
Beverdam, A.1
Claxton, C.2
Zhang, X.3
James, G.4
Harvey, K.F.5
Key, B.6
-
64
-
-
84878368948
-
MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-integrin/YAP/TAZ signaling axis
-
Tang, Y., et al. MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-integrin/YAP/TAZ signaling axis. Dev Cell 25, 402-416 (2013).
-
(2013)
Dev Cell
, vol.25
, pp. 402-416
-
-
Tang, Y.1
-
65
-
-
79953149145
-
Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF
-
Tamm, C., Bower, N. & Anneren, C. Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF. J Cell Sci 124, 1136-1144 (2011).
-
(2011)
J Cell Sci
, vol.124
, pp. 1136-1144
-
-
Tamm, C.1
Bower, N.2
Anneren, C.3
-
66
-
-
84900561874
-
Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma
-
Zhang, W. et al. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal 7, ra42 (2014).
-
(2014)
Sci Signal
, vol.7
, pp. ra42
-
-
Zhang, W.1
-
67
-
-
84903984143
-
Yap1 activation enables bypass of oncogenic kras addiction in pancreatic cancer
-
Kapoor, A. et al. Yap1 activation enables bypass of oncogenic kras addiction in pancreatic cancer. Cell 158, 185-197 (2014).
-
(2014)
Cell
, vol.158
, pp. 185-197
-
-
Kapoor, A.1
-
68
-
-
84904024982
-
KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
-
Shao, D. D. et al. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival. Cell 158, 171-184 (2014).
-
(2014)
Cell
, vol.158
, pp. 171-184
-
-
Shao, D.D.1
-
69
-
-
79955638751
-
Alcohol abuse, endoplasmic reticulum stress and pancreatitis
-
Pandol, S. J., Gorelick, F. S., Gerloff, A. & Lugea, A. Alcohol abuse, endoplasmic reticulum stress and pancreatitis. Dig Dis 28, 776-782 (2010).
-
(2010)
Dig Dis
, vol.28
, pp. 776-782
-
-
Pandol, S.J.1
Gorelick, F.S.2
Gerloff, A.3
Lugea, A.4
-
70
-
-
84866747307
-
Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade
-
Fujii, M. et al. Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade. Cell Cycle 11, 3373-3379 (2012).
-
(2012)
Cell Cycle
, vol.11
, pp. 3373-3379
-
-
Fujii, M.1
-
71
-
-
1542466792
-
Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo
-
Ling, Q. et al. Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. J Clin Invest 113, 38-48 (2004).
-
(2004)
J Clin Invest
, vol.113
, pp. 38-48
-
-
Ling, Q.1
-
72
-
-
0346362320
-
Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart
-
Krishnan, S., Deora, A. B., Annes, J. P., Osoria, J., Rifkin, D. B. & Hajjar, K. A. Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Dev Biol 265, 140-154 (2004).
-
(2004)
Dev Biol
, vol.265
, pp. 140-154
-
-
Krishnan, S.1
Deora, A.B.2
Annes, J.P.3
Osoria, J.4
Rifkin, D.B.5
Hajjar, K.A.6
-
73
-
-
70449428712
-
Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis
-
Jacovina, A. T. et al. Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis. J Clin Invest 119, 3384-3394 (2009).
-
(2009)
J Clin Invest
, vol.119
, pp. 3384-3394
-
-
Jacovina, A.T.1
-
74
-
-
34250885201
-
Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2
-
Ortiz-Zapater, E. et al. Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2. Am J Pathol 170, 1573-1584 (2007).
-
(2007)
Am J Pathol
, vol.170
, pp. 1573-1584
-
-
Ortiz-Zapater, E.1
-
75
-
-
79955775515
-
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer
-
Zheng, L. et al. Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS One 6, e19390 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e19390
-
-
Zheng, L.1
-
76
-
-
0027140743
-
Enhanced expression of annexin II in human pancreatic carcinoma cells and primary pancreatic cancers
-
Vishwanatha, J. K., Chiang, Y., Kumble, K. D., Hollingsworth, M. A. & Pour, P. M. Enhanced expression of annexin II in human pancreatic carcinoma cells and primary pancreatic cancers. Carcinogenesis 14, 2575-2579 (1993).
-
(1993)
Carcinogenesis
, vol.14
, pp. 2575-2579
-
-
Vishwanatha, J.K.1
Chiang, Y.2
Kumble, K.D.3
Hollingsworth, M.A.4
Pour, P.M.5
-
77
-
-
3042616114
-
Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion
-
Diaz, V. M., Hurtado, M., Thomson, T. M., Reventos, J. & Paciucci, R. Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro. Gut 53, 993-1000 (2004).
-
(2004)
Vitro. Gut
, Issue.53
, pp. 993-1000
-
-
Diaz, V.M.1
Hurtado, M.2
Thomson, T.M.3
Reventos, J.4
Paciucci, R.5
-
78
-
-
34247644369
-
Growth and regeneration of adult beta cells does not involve specialized progenitors
-
Teta, M., Rankin, M. M., Long, S. Y., Stein, G. M. & Kushner, J. A. Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell 12, 817-826 (2007).
-
(2007)
Dev Cell
, vol.12
, pp. 817-826
-
-
Teta, M.1
Rankin, M.M.2
Long, S.Y.3
Stein, G.M.4
Kushner, J.A.5
-
79
-
-
48549095907
-
Hedgehog signaling is required for effective regeneration of exocrine pancreas
-
Fendrich, V. et al. Hedgehog signaling is required for effective regeneration of exocrine pancreas. Gastroenterology 135, 621-631 (2008).
-
(2008)
Gastroenterology
, vol.135
, pp. 621-631
-
-
Fendrich, V.1
-
80
-
-
0035119871
-
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
-
Zulewski, H. et al. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50, 521-533 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 521-533
-
-
Zulewski, H.1
-
81
-
-
84898482404
-
MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes
-
Ardestani, A. et al. MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes. Nat Med 20, 385-397 (2014).
-
(2014)
Nat Med
, vol.20
, pp. 385-397
-
-
Ardestani, A.1
|