Hyperleptinemia suppresses aggravation of arthritis of collagen-antibody-induced arthritis in mice

Journal of Orthopaedic Science

Volumn 20, Issue 6, 2015, Pages 1106-1113

  Okano, Tadashi ^a   Koike, Tatsuya ^a,b   Tada, Masahiro ^a   Sugioka, Yuko ^a   Mamoto, Kenji ^a   Inui, Kentaro ^a   Okihana, Hiroyuki ^a   Ebihara, Ken ^c   Nakao, Kazuwa ^d   Nakamura, Hiroaki ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Search Institute for Bone and Arthritis Disease (SINBAD)   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN ANTIBODY; COLLAGEN TYPE 2; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ACUTE MONOCYTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE DESTRUCTION; CANCER PATIENT; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN CELL CULTURE; HYPERLEPTINEMIA; HYPERPLASIA; IN VITRO STUDY; JOINT SYNOVITIS; MONOCYTE MACROPHAGE PRECURSOR CELL; MOUSE; NONHUMAN; PAW; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SWELLING; SYNOVITIS; ANIMAL; ARTICULAR CARTILAGE; BLOOD; C57BL MOUSE; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL ARTHRITIS; IMMUNOHISTOCHEMISTRY; METABOLISM; NEEDLE BIOPSY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; RANDOMIZATION; SENSITIVITY AND SPECIFICITY; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BIOPSY, NEEDLE; CARTILAGE, ARTICULAR; COLLAGEN TYPE II; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; LEPTIN; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84947618707     PISSN: 09492658     EISSN: 14362023     Source Type: Journal    
DOI: 10.1007/s00776-015-0768-7     Document Type: Article

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