Leptin stimulates interleukin-6 production via janus kinase 2/signal transducer and activator of transcription 3 in rheumatoid synovial fibroblasts

Clinical and Experimental Rheumatology

Volumn 31, Issue 4, 2013, Pages 589-595

  Muraoka, S ^a   Kusunoki, N ^a   Takahashi, H ^b   Tsuchiya, K ^b   Kawai, S ^a  

^a Division of Rheumatology   (Japan)

^b TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

IL 6; JAK2; Leptin; Rheumatoid arthritis; STAT3

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IL 1BETA GENE; IL 6 GENE; LEPTIN RECEPTOR GENE; LONG TERM EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RHEUMATOID SYNOVIAL FIBROBLAST; SIGNAL TRANSDUCTION; SYNOVIOCYTE; SYNOVIUM; TNF ALPHA GENE; UPREGULATION; WESTERN BLOTTING;

ARTHRITIS, RHEUMATOID; FIBROBLASTS; HUMANS; INTERLEUKIN-6; JANUS KINASE 2; LEPTIN; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PRIMARY CELL CULTURE; RECEPTORS, LEPTIN; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SYNOVIAL MEMBRANE;

EID: 84883519072     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

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