-
1
-
-
54949106904
-
Mammalian glycosylation in immunity
-
Marth JD, Grewal PK. Mammalian glycosylation in immunity. Nat. Rev. Immunol. 8(11), 874-887 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.11
, pp. 874-887
-
-
Marth, J.D.1
Grewal, P.K.2
-
2
-
-
33748195979
-
Glycosylation in cellular mechanisms of health and disease
-
Ohtsubo K, Marth JD. Glycosylation in cellular mechanisms of health and disease. Cell 126(5), 855-867 (2006).
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 855-867
-
-
Ohtsubo, K.1
Marth, J.D.2
-
3
-
-
20844437106
-
Glycans in cancer and inflammation. Potential for therapeutics and diagnostics
-
Dube DH, Bertozzi CR. Glycans in cancer and inflammation. Potential for therapeutics and diagnostics. Nat. Rev. Drug Discov. 4(6), 477-488 (2005).
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, Issue.6
, pp. 477-488
-
-
Dube, D.H.1
Bertozzi, C.R.2
-
4
-
-
21744431575
-
The sweet and sour of cancer: Glycans as novel therapeutic targets
-
Fuster MM, Esko JD. The sweet and sour of cancer: glycans as novel therapeutic targets. Nat. Rev. Cancer 5, 526-542 (2005).
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 526-542
-
-
Fuster, M.M.1
Esko, J.D.2
-
6
-
-
67649860671
-
Combined approaches to the synthesis and study of glycoproteins
-
Bernardes GJL, Castagner B, Seeberger PH. Combined approaches to the synthesis and study of glycoproteins. ACS Chem. Biol. 4(9), 703-713 (2009).
-
(2009)
ACS Chem. Biol.
, vol.4
, Issue.9
, pp. 703-713
-
-
Bernardes, G.J.L.1
Castagner, B.2
Seeberger, P.H.3
-
7
-
-
77449115880
-
Advances in the biology and chemistry of sialic acids
-
Chen X, Varki A. Advances in the biology and chemistry of sialic acids. ACS Chem. Biol. 5(2), 163-176 (2010).
-
(2010)
ACS Chem. Biol.
, vol.5
, Issue.2
, pp. 163-176
-
-
Chen, X.1
Varki, A.2
-
8
-
-
0034444960
-
Achievements and challenges of sialic acid research
-
Schauer R. Achievements and challenges of sialic acid research. Glycoconj. J. 17(7-9), 485-499 (2000).
-
(2000)
Glycoconj. J.
, vol.17
, Issue.7-9
, pp. 485-499
-
-
Schauer, R.1
-
10
-
-
48149090000
-
Sialic acids in human health and disease
-
Varki A. Sialic acids in human health and disease. Trends Mol. Med. 14(8), 351-360 (2008).
-
(2008)
Trends Mol. Med.
, vol.14
, Issue.8
, pp. 351-360
-
-
Varki, A.1
-
11
-
-
84890937257
-
Glycocalyx engineering reveals a siglec-based mechanism for NK cell immunoevasion
-
Hudak JE, Canham SM, Bertozzi CR. Glycocalyx engineering reveals a siglec-based mechanism for NK cell immunoevasion. Nat. Chem. Biol. 10, 69-77 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 69-77
-
-
Hudak, J.E.1
Canham, S.M.2
Bertozzi, C.R.3
-
12
-
-
53449098078
-
Combinatorial chemoenzymatic synthesis and high-throughput screening of sialosides
-
Chokhawala HA, Huang SS, Lau K et al. Combinatorial chemoenzymatic synthesis and high-throughput screening of sialosides. ACS Chem. Biol. 3(9), 567-576 (2008).
-
(2008)
ACS Chem. Biol.
, vol.3
, Issue.9
, pp. 567-576
-
-
Chokhawala, H.A.1
Huang, S.S.2
Lau, K.3
-
13
-
-
0035015565
-
Siglecs in the immune system
-
Crocker PR, Varki A. Siglecs in the immune system. Immunology 103(2), 137-145 (2001).
-
(2001)
Immunology
, vol.103
, Issue.2
, pp. 137-145
-
-
Crocker, P.R.1
Varki, A.2
-
14
-
-
33750119810
-
Glycan microarray technologies: Tools to survey host specificity of influenza viruses
-
Stevens J, Blixt O, Paulson JC, Wilson IA. Glycan microarray technologies: tools to survey host specificity of influenza viruses. Nat. Rev. Microbiol. 4(11), 857-864 (2006).
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, Issue.11
, pp. 857-864
-
-
Stevens, J.1
Blixt, O.2
Paulson, J.C.3
Wilson, I.A.4
-
16
-
-
70350770831
-
Structural insight into mammalian sialyltransferases
-
Rao FV, Rich JR, Rakic B et al. Structural insight into mammalian sialyltransferases. Nat. Struct. Mol. Biol. 16(11), 1186-1188 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, Issue.11
, pp. 1186-1188
-
-
Rao, F.V.1
Rich, J.R.2
Rakic, B.3
-
17
-
-
84880567768
-
On-chip synthesis and screening of a sialoside library yields a high affinity ligand for siglec-7
-
Rillahan C, Schwartz E, Rademacher C et al. On-chip synthesis and screening of a sialoside library yields a high affinity ligand for siglec-7. ACS Chem. Biol. 8, 1417-1422 (2013).
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1417-1422
-
-
Rillahan, C.1
Schwartz, E.2
Rademacher, C.3
-
18
-
-
84921786419
-
Siglec-mediated regulation of immune cell function in disease
-
Macauley MS, Crocker PR, Paulson JC. Siglec-mediated regulation of immune cell function in disease. Nat. Rev. Immunol. 14, 653-666 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 653-666
-
-
Macauley, M.S.1
Crocker, P.R.2
Paulson, J.C.3
-
19
-
-
78149472708
-
Tumour-associated carbohydrate antigens in breast cancer
-
Cazet A, Julien S, Bobowski M, Burchell J, Delannoy P. Tumour-associated carbohydrate antigens in breast cancer. Breast Cancer Res. 12(3), 204 (2010).
-
(2010)
Breast Cancer Res.
, vol.12
, Issue.3
, pp. 204
-
-
Cazet, A.1
Julien, S.2
Bobowski, M.3
Burchell, J.4
Delannoy, P.5
-
20
-
-
77955769047
-
Consequences of the expression of sialylated antigens in breast cancer
-
Cazet A, Julien S, Bobowski M et al. Consequences of the expression of sialylated antigens in breast cancer. Carbohydr. Res. 345(10), 1377-1383 (2010).
-
(2010)
Carbohydr. Res.
, vol.345
, Issue.10
, pp. 1377-1383
-
-
Cazet, A.1
Julien, S.2
Bobowski, M.3
-
21
-
-
68249116079
-
From carbohydrate leads to glycomimetic drugs
-
Ernst B, Magnani JL. From carbohydrate leads to glycomimetic drugs. Nat. Rev. Drug Discov. 8(8), 661-677 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, Issue.8
, pp. 661-677
-
-
Ernst, B.1
Magnani, J.L.2
-
22
-
-
0042266719
-
A genetic approach to mammalian glycan function
-
Lowe JB, Marth JD. A genetic approach to mammalian glycan function. Annu. Rev. Biochem. 72, 643-691 (2003).
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 643-691
-
-
Lowe, J.B.1
Marth, J.D.2
-
23
-
-
34247590237
-
Synthetic glycopeptides from the e-selectin ligand 1 with varied sialyl lewis(x) structure as cell-adhesion inhibitors of E-selectin
-
Filser C, Kowalczyk D, Jones C et al. Synthetic glycopeptides from the e-selectin ligand 1 with varied sialyl lewis(x) structure as cell-adhesion inhibitors of E-selectin. Angew. Chem. Int. Ed. Engl. 46(12), 2108-2111 (2007).
-
(2007)
Angew. Chem. Int. Ed. Engl.
, vol.46
, Issue.12
, pp. 2108-2111
-
-
Filser, C.1
Kowalczyk, D.2
Jones, C.3
-
24
-
-
84856062692
-
Deal watch: Pfizer deal for selectin inhibitor highlights potential of glycomimetic drugs
-
Deal watch: Pfizer deal for selectin inhibitor highlights potential of glycomimetic drugs. Nat. Rev. Drug Discov. 10(12), 890-890 (2011).
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, Issue.12
, pp. 890-890
-
-
-
26
-
-
84874564716
-
Inhaled pan-selectin antagonist bimosiamose attenuates airway inflammation in COPD
-
Watz H, Bock D, Meyer M et al. Inhaled pan-selectin antagonist bimosiamose attenuates airway inflammation in COPD. Pulm. Pharmacol. Ther. 26(2), 265-270 (2013).
-
(2013)
Pulm. Pharmacol. Ther.
, vol.26
, Issue.2
, pp. 265-270
-
-
Watz, H.1
Bock, D.2
Meyer, M.3
-
27
-
-
77649208883
-
Low molecular weight antagonists of the myelin-associated glycoprotein: Synthesis, docking, and biological evaluation
-
Mesch S, Moser D, Strasser DS et al. Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation. J. Med. Chem. 53(4), 1597-1615 (2010).
-
(2010)
J. Med. Chem.
, vol.53
, Issue.4
, pp. 1597-1615
-
-
Mesch, S.1
Moser, D.2
Strasser, D.S.3
-
28
-
-
70349095283
-
Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza
-
Magano J. Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza. Chem. Rev. 109(9), 4398-4438 (2009).
-
(2009)
Chem. Rev.
, vol.109
, Issue.9
, pp. 4398-4438
-
-
Magano, J.1
-
29
-
-
77956233675
-
Rapid screening of lectins for multivalency effects with a glycodendrimer microarray
-
Pera NP, Branderhorst HM, Kooij R et al. Rapid screening of lectins for multivalency effects with a glycodendrimer microarray. Chembiochem 11(13), 1896-1904 (2010).
-
(2010)
Chembiochem
, vol.11
, Issue.13
, pp. 1896-1904
-
-
Pera, N.P.1
Branderhorst, H.M.2
Kooij, R.3
-
30
-
-
84862908985
-
Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22
-
Chen WC, Sigal DS, Saven A, Paulson JC. Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22. Leuk. Lymphoma 53(2), 208-210 (2012).
-
(2012)
Leuk. Lymphoma
, vol.53
, Issue.2
, pp. 208-210
-
-
Chen, W.C.1
Sigal, D.S.2
Saven, A.3
Paulson, J.C.4
-
31
-
-
84862585040
-
Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169
-
Chen WC, Kawasaki N, Nycholat CM et al. Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169. PloS ONE 7(6), e39039 (2012).
-
(2012)
PloS ONE
, vol.7
, Issue.6
, pp. e39039
-
-
Chen, W.C.1
Kawasaki, N.2
Nycholat, C.M.3
-
32
-
-
44349175443
-
Sialoside analogue arrays for rapid identification of high affinity siglec ligands
-
Blixt O, Han SF, Liao L et al. Sialoside analogue arrays for rapid identification of high affinity siglec ligands. J. Am. Chem. Soc. 2130(21), 6680-6681 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.2130
, Issue.21
, pp. 6680-6681
-
-
Blixt, O.1
Han, S.F.2
Liao, L.3
-
33
-
-
84900346441
-
Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas
-
Rillahan CD, Macauley MS, Schwartz E et al. Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas. Chem. Sci. 5, 2398-2406 (2014).
-
(2014)
Chem. Sci.
, vol.5
, pp. 2398-2406
-
-
Rillahan, C.D.1
Macauley, M.S.2
Schwartz, E.3
-
34
-
-
79960371234
-
Targeting siglecs-A novel pharmacological strategy for immuno-and glycotherapy
-
Jandus C, Simon H-U, Von Gunten S. Targeting siglecs-A novel pharmacological strategy for immuno-and glycotherapy. Biochem. Pharmacol. 82(4), 323-332 (2011).
-
(2011)
Biochem. Pharmacol.
, vol.82
, Issue.4
, pp. 323-332
-
-
Jandus, C.1
Simon, H.-U.2
Von Gunten, S.3
-
35
-
-
65349147691
-
Siglecs as targets for therapy in immune-cell-mediated disease
-
O'Reilly MK, Paulson JC. Siglecs as targets for therapy in immune-cell-mediated disease. Trends Pharmacol. Sci. 30(5), 240-248 (2009).
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, Issue.5
, pp. 240-248
-
-
O'Reilly, M.K.1
Paulson, J.C.2
-
36
-
-
84947609006
-
-
US FDA. www.fda.gov
-
US FDA
-
-
-
37
-
-
67749116255
-
Biologics through chemistry: Total synthesis of a proposed dual-acting vaccine targeting ovarian cancer orchestration of oligosaccharide and polypeptide domains
-
Zhu J, Wan Q, Ragupathi G, George CM, Livingston PO, Danishefsky SJ. Biologics through chemistry: total synthesis of a proposed dual-acting vaccine targeting ovarian cancer orchestration of oligosaccharide and polypeptide domains. J. Am. Chem. Soc. 131(11), 4151-4158 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, Issue.11
, pp. 4151-4158
-
-
Zhu, J.1
Wan, Q.2
Ragupathi, G.3
George, C.M.4
Livingston, P.O.5
Danishefsky, S.J.6
-
38
-
-
70349907941
-
Synthetic carbohydratebased anticancer vaccines: The Memorial Sloan-Kettering experience
-
Zhu J, Warren JD, Danishefsky SJ. Synthetic carbohydratebased anticancer vaccines: The Memorial Sloan-Kettering experience. Expert Rev. Vaccines 8(10), 1399-1413 (2009).
-
(2009)
Expert Rev. Vaccines
, vol.8
, Issue.10
, pp. 1399-1413
-
-
Zhu, J.1
Warren, J.D.2
Danishefsky, S.J.3
-
39
-
-
77950480397
-
Carbohydrate vaccines: Developing sweet solutions to sticky situations?
-
Astronomo RD, Burton DR. Carbohydrate vaccines: developing sweet solutions to sticky situations? Nat. Rev. Drug Disov. 9(4), 308-324 (2010).
-
(2010)
Nat. Rev. Drug Disov.
, vol.9
, Issue.4
, pp. 308-324
-
-
Astronomo, R.D.1
Burton, D.R.2
-
40
-
-
84867183647
-
The failed theratope vaccine: 10 years later
-
Zeichner SB. The failed theratope vaccine: 10 years later. J. Am. Osteopath. Assoc. 112(8), 482-483 (2012).
-
(2012)
J. Am. Osteopath. Assoc.
, vol.112
, Issue.8
, pp. 482-483
-
-
Zeichner, S.B.1
-
41
-
-
84885105341
-
A vision for vaccines built from fully synthetic tumor-associated antigens: From the laboratory to the clinic
-
Wilson RM, Danishefsky SJ. A vision for vaccines built from fully synthetic tumor-associated antigens: from the laboratory to the clinic. J. Am. Chem. Soc. 135, 14462-14472 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 14462-14472
-
-
Wilson, R.M.1
Danishefsky, S.J.2
-
43
-
-
33947545682
-
Sialic acids: Carbohydrate moieties that influence the biological and physical properties of biopharmaceutical proteins and living cells
-
Byrne B, Donohoe GG, O'Kennedy R. Sialic acids: carbohydrate moieties that influence the biological and physical properties of biopharmaceutical proteins and living cells. Drug Discov. Today 12(7-8), 319-326 (2007).
-
(2007)
Drug Discov. Today
, vol.12
, Issue.7-8
, pp. 319-326
-
-
Byrne, B.1
Donohoe, G.G.2
O'Kennedy, R.3
|