On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7

ACS Chemical Biology

Volumn 8, Issue 7, 2013, Pages 1417-1422

  Rillahan, Cory D ^a   Schwartz, Erik ^a   Rademacher, Christoph ^b   McBride, Ryan ^a   Rangarajan, Janani ^a   Fokin, Valery V ^a   Paulson, James C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE DERIVATIVE; LIGAND; LIPOSOME; NANOPARTICLE; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIALIC ACID DERIVATIVE; SIALOSIDE; SIGLEC 7; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CELL; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; MICROARRAY ANALYSIS; MOLECULAR DOCKING; MOLECULAR LIBRARY; ON CHIP SYNTHESIS; PRIORITY JOURNAL; SCREENING; SYNTHESIS;

ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; FLUORESCEINS; HUMANS; JURKAT CELLS; LECTINS; LIGANDS; LIPOSOMES; MICROARRAY ANALYSIS; MOLECULAR STRUCTURE; SIALIC ACIDS; SMALL MOLECULE LIBRARIES;

EID: 84880567768     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400125w     Document Type: Article

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