Cytoplasmic translocation, aggregation, and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesis

Cell Death and Differentiation

Volumn 22, Issue 12, 2015, Pages 2087-2097

  Fung, G ^a   Shi, J ^a   Deng, H ^a   Hou, J ^a,b   Wang, C ^a   Hong, A ^a   Zhang, J ^a   Jia, W ^c   Luo, H ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHENGDU MILITARY GENERAL HOSPITAL   (China)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; DOUBLE STRANDED RNA; GLUTAMINE; LEUCINE; PROTEASOME; PROTEIN AGGREGATE; SMALL INTERFERING RNA; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEASE 2A; VIRAL PROTEASE 3C; VIRUS PROTEIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA BINDING PROTEIN; ISOPROTEIN; PROTEINASE; TDP-43 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CELL AGGREGATION; CELL DIVISION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COXSACKIEVIRUS B3; CYTOPLASM; CYTOPLASMIC TRANSLOCATION; ENTEROVIRUS INFECTION; FEMALE; GENE TRANSLOCATION; HUMAN; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TDP 43 PROTEINOPATHY; TRANSIENT TRANSFECTION; VIRUS PATHOGENESIS; VIRUS TITRATION; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; ENTEROVIRUS B; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; HELA CELL LINE; MALE; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE; VIRUS REPLICATION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA-BINDING PROTEINS; ENDOPEPTIDASES; ENTEROVIRUS B, HUMAN; HELA CELLS; HUMANS; MALE; MICE; MICROSCOPY, FLUORESCENCE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ISOFORMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; VIRUS REPLICATION;

EID: 84947491523     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.58     Document Type: Article

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