Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling

Autophagy

Volumn 9, Issue 10, 2013, Pages 1591-1603

  Shi, Junyan ^a   Wong, Jerry ^a   Piesik, Paulina ^a   Fung, Gabriel ^a   Zhang, Jingchun ^a   Jagdeo, Julienne ^b   Li, LiXiaotao ^c,d   Jan, Eric ^b   Luo, Honglin ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c EAST CHINA NORMAL UNIVERSITY   (China)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cleavage; Coxsackievirus; NFKB signaling; Selective autophagy; SQSTM1 p62; Viral protease 2A

Indexed keywords

ADAPTOR PROTEIN; AMINO ACID; ANTIOXIDANT; COMPLEMENTARY DNA; GLYCINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MICROTUBULE ASSOCIATED PROTEIN 1; NUCLEAR FACTOR; NUCLEAR FACTOR ERYTHROID DERIVED DERIVED 2 LIKE 2; POLYPEPTIDE; PROTEINASE; PROTEINASE INHIBITOR; RNA; SEQUESTOSOME 1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRITON X 100; UBIQUITIN; UNCLASSIFIED DRUG; VIRAL PROTEASE 2A; VIRUS PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NFKB1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN; UBIQUITINATED PROTEIN;

ARTICLE; AUTOPHAGY; COXSACKIE VIRUS B3; ENTEROVIRUS; ENZYME ACTIVITY; ENZYME ASSAY; FLUORESCENCE MICROSCOPE; HELA CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SELECTIVE AUTOPHAGY; SIGNAL TRANSDUCTION; VIRUS INFECTION; VIRUS REPLICATION; WESTERN BLOTTING; GENETICS; HELA CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; PHAGOSOME; PHYSIOLOGY;

COXSACKIEVIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AUTOPHAGY; ENTEROVIRUS B, HUMAN; HELA CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; NF-KAPPA B P50 SUBUNIT; PHAGOSOMES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UBIQUITINATED PROTEINS;

EID: 84885660912     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.26059     Document Type: Article

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