Synthesis, photophysical properties, and biological evaluation of trans-bisthioglycosylated tetrakis(fluorophenyl)chlorin for photodynamic therapy

Journal of Medicinal Chemistry

Volumn 58, Issue 21, 2015, Pages 8658-8670

  Hirohara, Shiho ^a   Oka, Chio ^b   Totani, Masayasu ^b   Obata, Makoto ^c   Yuasa, Junpei ^b   Ito, Hiromu ^d   Tamura, Masato ^d   Matsui, Hirofumi ^d   Kakiuchi, Kiyomi ^b   Kawai, Tsuyoshi ^b   Kawaichi, Masashi ^b   Tanihara, Masao ^b  

^a UBE NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5,15 BIS[4 (BETA DEXTRO GLUCOPYRANOSYLTHIO) 2,3,5,6 TETRAFLUOROPHENYL] 10,20 BIS(PENTAFLUOROPHENYL) 2,3 [METHANO(N METHYL)IMINOMETHANO]CHLORIN; ANTINEOPLASTIC AGENT; BISTHIOGLYCOSYLATED TETRAKIS(FLUOROPHENYL)CHLORIN; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CHLORINATED HYDROCARBON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CANCER; BREAST CANCER; CANCER CELL; CANCER CELL LINE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; GLIOBLASTOMA CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOMA CELL; METASTASIS; MOUSE; MUCOSA CELL; NONHUMAN; PHOTOCYTOTOXICITY; PHOTODYNAMIC THERAPY; SKIN CANCER; STOMACH CANCER; STOMACH CARCINOMA; UTERINE CERVIX CANCER; ANIMAL; BAGG ALBINO MOUSE; BREAST; BREAST NEOPLASMS; CHEMISTRY; DRUG EFFECTS; HALOGENATION; NEOPLASMS; PATHOLOGY; PHOTOCHEMOTHERAPY; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HALOGENATION; HUMANS; HYDROCARBONS, CHLORINATED; MICE; MICE, INBRED BALB C; NEOPLASMS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

EID: 84947461264     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b01262     Document Type: Article

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