Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy

Journal of Controlled Release

Volumn 157, Issue 2, 2012, Pages 196-205

  Bovis, Melissa J ^a   Woodhams, Josephine H ^a   Loizidou, Marilena ^a   Scheglmann, Dietrich ^b   Bown, Stephen G ^a   MacRobert, Alexander J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Biolitec AG   (Germany)

Author keywords

Liposomes; m THPC; Pharmacokinetics; Photodynamic therapy; Photosensitiser; Polyethylene glycol

Indexed keywords

BIODISTRIBUTIONS; BLOOD PLASMA; CIRCULATION TIME; COMPARTMENTAL ANALYSIS; DRUG-LIGHT INTERVALS; HALF LIVES; IN-VIVO; LIPOSOMAL FORMULATION; LIPOSOMAL NANOCARRIERS; M-THPC; NORMAL TISSUE; NORMAL TISSUE DAMAGE; PEGYLATED LIPOSOMES; PEGYLATION; PHOTOSENSITISER; TARGET TISSUES;

BIOCHEMISTRY; BLOOD; DRUG DOSAGE; GLYCOLS; HISTOLOGY; LIGHT SENSITIVE MATERIALS; LIPOSOMES; PHARMACOKINETICS; PHOSPHOLIPIDS; PHOTOSENSITIVITY; POLYETHYLENE GLYCOLS; TUMORS;

PHOTODYNAMIC THERAPY;

LIPOSOME; TEMOPORFIN; TETRAKIS(3 HYDROXYPHENYL)CHLORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; DRUG TUMOR LEVEL; FEMALE; FIBROSARCOMA; IN VIVO STUDY; LIPOSOMAL DELIVERY; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOSENSITIVITY; PRIORITY JOURNAL; RAT; TISSUE INJURY; TUMOR NECROSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FIBROSARCOMA; LIGHT; LIPOSOMES; MESOPORPHYRINS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 84855813102     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.09.085     Document Type: Article

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