An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis

RNA

Volumn 21, Issue 12, 2015, Pages 2103-2118

  Lin, Ching Jung ^a   Smibert, Peter ^a,b,g   Zhao, Xiaoyu ^c   Hu, Jennifer F ^d   Ramroop, Johnny ^e,f   Kellner, Stefanie M ^d   Benton, Matthew A ^b,h   Govind, Shubha ^e,f   Dedon, Peter C ^d   Sternglanz, Rolf ^c   Lai, Eric C ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c STONY BROOK UNIVERSITY   (United States)

^d Massachusetts Institute of Technology   (United States)

^e CITY COLLEGE OF NEW YORK   (United States)

^f CITY UNIVERSITY OF NEW YORK   (United States)

^g NEW YORK GENOME CENTER   (United States)

^h UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Drosophila; Kae1; N6 Threonylcarbamoyladenosine; T6A

Indexed keywords

BUD32 PROTEIN; HISTONE H3; KAE1 PROTEIN; N 6 THREONYLCARBAMOYL ADENOSINE; PROTEIN; SUA5 PROTEIN; TRANSFER RNA; UNCLASSIFIED DRUG; ADENOSINE; DROSOPHILA PROTEIN; N(6)-(N-THREONYLCARBONYL)ADENOSINE;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY SIZE; CELL DIVISION; CELL LINE; CELL MATURATION; CELL SIZE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EYE DEVELOPMENT; FEMALE; FUNGUS GROWTH; GENE INSERTION; GENE ISOLATION; GENE LOCUS; GENE LOSS; GENE MUTATION; GENE SEQUENCE; GENE SILENCING; GENETIC CODE; GENETIC COMPLEMENTATION; GENETIC TRANSCRIPTION; GENOME ANALYSIS; GENOTYPE; HEMATOPOIESIS; HEMATOPOIETIC TISSUE; HEMIZYGOTE; HETEROZYGOTE; IMAGINAL DISC; INSECT GENETICS; LARVAL STAGE; LIMIT OF DETECTION; LYMPH NODE; MALE; METAMORPHOSIS; MISSENSE MUTATION; MITOSIS; MITOTIC RECOMBINATION; MUSCULOSKELETAL SYSTEM PARAMETERS; MUTAGENESIS; NONHUMAN; NONSENSE MUTATION; NULL ALLELE; ORGAN SIZE; ORTHOLOGY; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PUPATION; RNA ANALYSIS; RNA SYNTHESIS; SIGNAL TRANSDUCTION; TISSUE GROWTH; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CONSERVED SEQUENCE; CYTOLOGY; DROSOPHILA MELANOGASTER; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

ADENOSINE; ALLELES; AMINO ACID SEQUENCE; ANIMALS; BIOSYNTHETIC PATHWAYS; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENETIC COMPLEMENTATION TEST; IMAGINAL DISCS; LARVA; MALE; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; ORGAN SPECIFICITY; SACCHAROMYCES CEREVISIAE;

EID: 84947427227     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.053934.115     Document Type: Article

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