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Volumn 56, Issue , 2015, Pages 26-34

The antidepressant mechanism of action of vagus nerve stimulation: Evidence from preclinical studies

Author keywords

Major depressive disorder; The monoaminergic hypothesis of major depressive disorder; The neural plasticity hypothesis of major depressive disorder; Vagus nerve stimulation

Indexed keywords

MONOAMINE; NORADRENALIN; SEROTONIN;

EID: 84947260674     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2015.06.019     Document Type: Review
Times cited : (63)

References (130)
  • 1
    • 84879288188 scopus 로고    scopus 로고
    • Vagus nerve stimulation therapy randomized to different amounts of electrical charge for treatment-resistant depression: acute and chronic effects
    • Aaronson S.T., et al. Vagus nerve stimulation therapy randomized to different amounts of electrical charge for treatment-resistant depression: acute and chronic effects. Brain Stimul. 2013, 6(4):631-640.
    • (2013) Brain Stimul. , vol.6 , Issue.4 , pp. 631-640
    • Aaronson, S.T.1
  • 2
    • 4544300320 scopus 로고    scopus 로고
    • Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
    • Alonso J., et al. Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr. Scand. Suppl. 2004, 420:21-27.
    • (2004) Acta Psychiatr. Scand. Suppl. , vol.420 , pp. 21-27
    • Alonso, J.1
  • 3
    • 0028289257 scopus 로고
    • Nucleus tractus solitarius - gateway to neural circulatory control
    • Andresen M.C., Kunze D.L. Nucleus tractus solitarius - gateway to neural circulatory control. Annu. Rev. Physiol. 1994, 56:93-116.
    • (1994) Annu. Rev. Physiol. , vol.56 , pp. 93-116
    • Andresen, M.C.1    Kunze, D.L.2
  • 4
    • 0025838807 scopus 로고
    • Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology
    • Aston-Jones G., et al. Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. Prog. Brain Res. 1991, 88:47-75.
    • (1991) Prog. Brain Res. , vol.88 , pp. 47-75
    • Aston-Jones, G.1
  • 5
    • 1542347181 scopus 로고    scopus 로고
    • Numerous GABAergic afferents to locus ceruleus in the pericerulear dendritic zone: possible interneuronal pool
    • Aston-Jones G., Zhu Y., Card J.P. Numerous GABAergic afferents to locus ceruleus in the pericerulear dendritic zone: possible interneuronal pool. J. Neurosci. 2004, 24(9):2313-2321.
    • (2004) J. Neurosci. , vol.24 , Issue.9 , pp. 2313-2321
    • Aston-Jones, G.1    Zhu, Y.2    Card, J.P.3
  • 6
    • 77952330742 scopus 로고    scopus 로고
    • Two-year outcome of vagus nerve stimulation in treatment-resistant depression
    • Bajbouj M., et al. Two-year outcome of vagus nerve stimulation in treatment-resistant depression. J. Clin. Psychopharmacol 2010, 30(3):273-281.
    • (2010) J. Clin. Psychopharmacol , vol.30 , Issue.3 , pp. 273-281
    • Bajbouj, M.1
  • 7
    • 0018853233 scopus 로고
    • Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists
    • Baraban J.M., Aghajanian G.K. Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists. Neuropharmacology 1980, 19(4):355-363.
    • (1980) Neuropharmacology , vol.19 , Issue.4 , pp. 355-363
    • Baraban, J.M.1    Aghajanian, G.K.2
  • 9
    • 0028103989 scopus 로고
    • Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders
    • Benkelfat C., et al. Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders. Arch. Gen. Psychiatry 1994, 51(9):687-697.
    • (1994) Arch. Gen. Psychiatry , vol.51 , Issue.9 , pp. 687-697
    • Benkelfat, C.1
  • 10
    • 0041386052 scopus 로고    scopus 로고
    • Vagus-nerve stimulation for the treatment of epilepsy
    • Ben-Menachem E. Vagus-nerve stimulation for the treatment of epilepsy. Lancet Neurol. 2002, 1(8):477-482.
    • (2002) Lancet Neurol. , vol.1 , Issue.8 , pp. 477-482
    • Ben-Menachem, E.1
  • 11
    • 34248381347 scopus 로고    scopus 로고
    • Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods
    • Berlim M.T., Turecki G. Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods. Can. J. Psychiatry 2007, 52(1):46-54.
    • (2007) Can. J. Psychiatry , vol.52 , Issue.1 , pp. 46-54
    • Berlim, M.T.1    Turecki, G.2
  • 12
    • 84874689023 scopus 로고    scopus 로고
    • A patient-level meta-analysis of studies evaluating vagus nerve stimulation therapy for treatment-resistant depression
    • Berry S.M., et al. A patient-level meta-analysis of studies evaluating vagus nerve stimulation therapy for treatment-resistant depression. Med. Devices (Auckl.) 2013, 6:17-35.
    • (2013) Med. Devices (Auckl.) , vol.6 , pp. 17-35
    • Berry, S.M.1
  • 13
    • 79959362201 scopus 로고    scopus 로고
    • Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus
    • Biggio F., et al. Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus. Int. J. Neuropsychopharmacol. 2009, 12(9):1209-1221.
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , Issue.9 , pp. 1209-1221
    • Biggio, F.1
  • 14
    • 0037338273 scopus 로고    scopus 로고
    • The pharmacology of putative early-onset antidepressant strategies
    • Blier P. The pharmacology of putative early-onset antidepressant strategies. Eur. Neuropsychopharmacol. 2003, 13(2):57-66.
    • (2003) Eur. Neuropsychopharmacol. , vol.13 , Issue.2 , pp. 57-66
    • Blier, P.1
  • 15
    • 0033970356 scopus 로고    scopus 로고
    • Hippocampal volume reduction in major depression
    • Bremner J.D., et al. Hippocampal volume reduction in major depression. Am. J. Psychiatry 2000, 157(1):115-118.
    • (2000) Am. J. Psychiatry , vol.157 , Issue.1 , pp. 115-118
    • Bremner, J.D.1
  • 16
    • 0033051299 scopus 로고    scopus 로고
    • Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats
    • Brezun J.M., Daszuta A. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience 1999, 89(4):999-1002.
    • (1999) Neuroscience , vol.89 , Issue.4 , pp. 999-1002
    • Brezun, J.M.1    Daszuta, A.2
  • 17
    • 0031782136 scopus 로고    scopus 로고
    • Tryptophan depletion during continuous CSF sampling in healthy human subjects
    • Carpenter L.L., et al. Tryptophan depletion during continuous CSF sampling in healthy human subjects. Neuropsychopharmacology 1998, 19(1):26-35.
    • (1998) Neuropsychopharmacology , vol.19 , Issue.1 , pp. 26-35
    • Carpenter, L.L.1
  • 18
    • 0018097341 scopus 로고
    • Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique
    • Cedarbaum J.M., Aghajanian G.K. Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique. J. Comp. Neurol. 1978, 178(1):1-16.
    • (1978) J. Comp. Neurol. , vol.178 , Issue.1 , pp. 1-16
    • Cedarbaum, J.M.1    Aghajanian, G.K.2
  • 19
    • 0027359525 scopus 로고
    • Basic fibroblast growth factor (bFGF, FGF-2) immunoreactivity exists in the noradrenaline, adrenaline and 5-HT nerve cells of the rat brain
    • Chadi G., et al. Basic fibroblast growth factor (bFGF, FGF-2) immunoreactivity exists in the noradrenaline, adrenaline and 5-HT nerve cells of the rat brain. Neurosci. Lett. 1993, 160(2):171-176.
    • (1993) Neurosci. Lett. , vol.160 , Issue.2 , pp. 171-176
    • Chadi, G.1
  • 20
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B., et al. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry 2001, 50(4):260-265.
    • (2001) Biol. Psychiatry , vol.50 , Issue.4 , pp. 260-265
    • Chen, B.1
  • 21
    • 33845334877 scopus 로고    scopus 로고
    • Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons
    • Chen M.J., et al. Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons. Cell. Signal. 2007, 19(1):114-128.
    • (2007) Cell. Signal. , vol.19 , Issue.1 , pp. 114-128
    • Chen, M.J.1
  • 22
    • 0028999645 scopus 로고
    • Post-training unilateral vagal stimulation enhances retention performance in the rat
    • Clark K.B., et al. Post-training unilateral vagal stimulation enhances retention performance in the rat. Neurobiol. Learn. Mem. 1995, 63(3):213-216.
    • (1995) Neurobiol. Learn. Mem. , vol.63 , Issue.3 , pp. 213-216
    • Clark, K.B.1
  • 23
    • 0031734255 scopus 로고    scopus 로고
    • Posttraining electrical stimulation of vagal afferents with concomitant vagal efferent inactivation enhances memory storage processes in the rat
    • Clark K.B., et al. Posttraining electrical stimulation of vagal afferents with concomitant vagal efferent inactivation enhances memory storage processes in the rat. Neurobiol. Learn. Mem. 1998, 70(3):364-373.
    • (1998) Neurobiol. Learn. Mem. , vol.70 , Issue.3 , pp. 364-373
    • Clark, K.B.1
  • 24
    • 0033360551 scopus 로고    scopus 로고
    • Enhanced recognition memory following vagus nerve stimulation in human subjects
    • Clark K.B., et al. Enhanced recognition memory following vagus nerve stimulation in human subjects. Nat. Neurosci. 1999, 2(1):94-98.
    • (1999) Nat. Neurosci. , vol.2 , Issue.1 , pp. 94-98
    • Clark, K.B.1
  • 25
    • 84862071705 scopus 로고    scopus 로고
    • Brain blood-flow change with acute vagus nerve stimulation in treatment-refractory major depressive disorder
    • Conway C.R., et al. Brain blood-flow change with acute vagus nerve stimulation in treatment-refractory major depressive disorder. Brain Stimul. 2012, 5(2):163-171.
    • (2012) Brain Stimul. , vol.5 , Issue.2 , pp. 163-171
    • Conway, C.R.1
  • 26
    • 84883773498 scopus 로고    scopus 로고
    • Association of cerebral metabolic activity changes with vagus nerve stimulation antidepressant response in treatment-resistant depression
    • Conway C.R., et al. Association of cerebral metabolic activity changes with vagus nerve stimulation antidepressant response in treatment-resistant depression. Brain Stimul. 2013, 6(5):788-797.
    • (2013) Brain Stimul. , vol.6 , Issue.5 , pp. 788-797
    • Conway, C.R.1
  • 27
    • 79953787411 scopus 로고    scopus 로고
    • Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 year
    • Cristancho P., et al. Effectiveness and safety of vagus nerve stimulation for severe treatment-resistant major depression in clinical practice after FDA approval: outcomes at 1 year. J. Clin. Psychiatry 2011, 72(10):1376-1382.
    • (2011) J. Clin. Psychiatry , vol.72 , Issue.10 , pp. 1376-1382
    • Cristancho, P.1
  • 28
    • 45149095307 scopus 로고    scopus 로고
    • Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by Vagal nerve stimulation
    • Cunningham J.T., et al. Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by Vagal nerve stimulation. Neuropsychopharmacology 2008, 33(8):1884-1895.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.8 , pp. 1884-1895
    • Cunningham, J.T.1
  • 29
    • 33745947013 scopus 로고    scopus 로고
    • Effect of vagus nerve stimulation on serotonergic and noradrenergic transmission
    • Dorr A.E., Debonnel G. Effect of vagus nerve stimulation on serotonergic and noradrenergic transmission. J. Pharmacol. Exp. Ther. 2006, 318(2):890-898.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , Issue.2 , pp. 890-898
    • Dorr, A.E.1    Debonnel, G.2
  • 30
    • 3242745166 scopus 로고    scopus 로고
    • Depression: a case of neuronal life and death?
    • Duman R.S. Depression: a case of neuronal life and death?. Biol. Psychiatry 2004, 56(3):140-145.
    • (2004) Biol. Psychiatry , vol.56 , Issue.3 , pp. 140-145
    • Duman, R.S.1
  • 31
    • 0035672760 scopus 로고    scopus 로고
    • Regulation of adult neurogenesis by antidepressant treatment
    • Duman R.S., Nakagawa S., Malberg J. Regulation of adult neurogenesis by antidepressant treatment. Neuropsychopharmacology 2001, 25(6):836-844.
    • (2001) Neuropsychopharmacology , vol.25 , Issue.6 , pp. 836-844
    • Duman, R.S.1    Nakagawa, S.2    Malberg, J.3
  • 32
    • 0033768295 scopus 로고    scopus 로고
    • Vagus nerve stimulation is associated with mood improvements in epilepsy patients
    • Elger G., et al. Vagus nerve stimulation is associated with mood improvements in epilepsy patients. Epilepsy Res. 2000, 42(2-3):203-210.
    • (2000) Epilepsy Res. , vol.42 , Issue.2-3 , pp. 203-210
    • Elger, G.1
  • 33
    • 0023742981 scopus 로고
    • Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain
    • Ennis M., Aston-Jones G. Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain. J. Neurosci. 1988, 8(10):3644-3657.
    • (1988) J. Neurosci. , vol.8 , Issue.10 , pp. 3644-3657
    • Ennis, M.1    Aston-Jones, G.2
  • 34
    • 0024384877 scopus 로고
    • GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla
    • Ennis M., Aston-Jones G. GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla. J. Neurosci. 1989, 9(8):2973-2981.
    • (1989) J. Neurosci. , vol.9 , Issue.8 , pp. 2973-2981
    • Ennis, M.1    Aston-Jones, G.2
  • 35
    • 0031789814 scopus 로고    scopus 로고
    • Neurogenesis in the adult human hippocampus
    • Eriksson P.S., et al. Neurogenesis in the adult human hippocampus. Nat. Med. 1998, 4(11):1313-1317.
    • (1998) Nat. Med. , vol.4 , Issue.11 , pp. 1313-1317
    • Eriksson, P.S.1
  • 36
    • 0030566703 scopus 로고    scopus 로고
    • Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus
    • Florin-Lechner S.M., et al. Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus. Brain Res. 1996, 742(1-2):89-97.
    • (1996) Brain Res. , vol.742 , Issue.1-2 , pp. 89-97
    • Florin-Lechner, S.M.1
  • 37
    • 35448949501 scopus 로고    scopus 로고
    • Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain
    • Follesa P., et al. Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain. Brain Res. 2007, 1179:28-34.
    • (2007) Brain Res. , vol.1179 , pp. 28-34
    • Follesa, P.1
  • 38
    • 4544275669 scopus 로고    scopus 로고
    • Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews
    • Fuchs E., Czeh B., Flugge G. Examining novel concepts of the pathophysiology of depression in the chronic psychosocial stress paradigm in tree shrews. Behav. Pharmacol. 2004, 15(5-6):315-325.
    • (2004) Behav. Pharmacol. , vol.15 , Issue.5-6 , pp. 315-325
    • Fuchs, E.1    Czeh, B.2    Flugge, G.3
  • 39
    • 84860441405 scopus 로고    scopus 로고
    • Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain
    • Furmaga H., Carreno F.R., Frazer A. Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain. PLOS ONE 2012, 7(5):e34844.
    • (2012) PLOS ONE , vol.7 , Issue.5 , pp. e34844
    • Furmaga, H.1    Carreno, F.R.2    Frazer, A.3
  • 40
    • 84873407488 scopus 로고    scopus 로고
    • Vagus nerve stimulation ameliorated deficits in one-way active avoidance learning and stimulated hippocampal neurogenesis in bulbectomized rats
    • Gebhardt N., et al. Vagus nerve stimulation ameliorated deficits in one-way active avoidance learning and stimulated hippocampal neurogenesis in bulbectomized rats. Brain Stimul. 2013, 6(1):78-83.
    • (2013) Brain Stimul. , vol.6 , Issue.1 , pp. 78-83
    • Gebhardt, N.1
  • 41
    • 24044463171 scopus 로고    scopus 로고
    • A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression
    • George M.S., et al. A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression. Biol. Psychiatry 2005, 58(5):364-373.
    • (2005) Biol. Psychiatry , vol.58 , Issue.5 , pp. 364-373
    • George, M.S.1
  • 42
    • 0028355267 scopus 로고
    • Fos-containing neurons in medulla and pons after unilateral stimulation of the afferent abdominal vagus in conscious rabbits
    • Gieroba Z.J., Blessing W.W. Fos-containing neurons in medulla and pons after unilateral stimulation of the afferent abdominal vagus in conscious rabbits. Neuroscience 1994, 59(4):851-858.
    • (1994) Neuroscience , vol.59 , Issue.4 , pp. 851-858
    • Gieroba, Z.J.1    Blessing, W.W.2
  • 43
    • 0027772108 scopus 로고
    • Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii
    • Glaum S.R., Miller R.J. Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii. J. Neurophysiol. 1993, 70(6):2669-2672.
    • (1993) J. Neurophysiol. , vol.70 , Issue.6 , pp. 2669-2672
    • Glaum, S.R.1    Miller, R.J.2
  • 44
    • 84919625092 scopus 로고    scopus 로고
    • Vagus nerve stimulation has antidepressant effects in the kainic acid model for temporal lobe epilepsy
    • Grimonprez A., et al. Vagus nerve stimulation has antidepressant effects in the kainic acid model for temporal lobe epilepsy. Brain Stimul. 2014, 8:13-20.
    • (2014) Brain Stimul. , vol.8 , pp. 13-20
    • Grimonprez, A.1
  • 46
    • 16844385775 scopus 로고    scopus 로고
    • Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions
    • Gronli J., et al. Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions. Physiol. Behav. 2005, 84(4):571-577.
    • (2005) Physiol. Behav. , vol.84 , Issue.4 , pp. 571-577
    • Gronli, J.1
  • 47
    • 36349027843 scopus 로고    scopus 로고
    • Is it time to reassess the BDNF hypothesis of depression?
    • Groves J.O. Is it time to reassess the BDNF hypothesis of depression?. Mol. Psychiatry 2007, 12(12):1079-1088.
    • (2007) Mol. Psychiatry , vol.12 , Issue.12 , pp. 1079-1088
    • Groves, J.O.1
  • 48
    • 17444369079 scopus 로고    scopus 로고
    • Recordings from the rat locus coeruleus during acute vagal nerve stimulation in the anaesthetised rat
    • Groves D.A., Bowman E.M., Brown V.J. Recordings from the rat locus coeruleus during acute vagal nerve stimulation in the anaesthetised rat. Neurosci. Lett. 2005, 379(3):174-179.
    • (2005) Neurosci. Lett. , vol.379 , Issue.3 , pp. 174-179
    • Groves, D.A.1    Bowman, E.M.2    Brown, V.J.3
  • 49
    • 80855123608 scopus 로고    scopus 로고
    • Depression, antidepressants, and neurogenesis: a critical reappraisal
    • Hanson N.D., Owens M.J., Nemeroff C.B. Depression, antidepressants, and neurogenesis: a critical reappraisal. Neuropsychopharmacology 2011, 36(13):2589-2602.
    • (2011) Neuropsychopharmacology , vol.36 , Issue.13 , pp. 2589-2602
    • Hanson, N.D.1    Owens, M.J.2    Nemeroff, C.B.3
  • 50
    • 0036623567 scopus 로고    scopus 로고
    • Depression and anxiety in epilepsy patients
    • Harden C.L. Depression and anxiety in epilepsy patients. Epilepsy Behav. 2002, 3(3):296.
    • (2002) Epilepsy Behav. , vol.3 , Issue.3 , pp. 296
    • Harden, C.L.1
  • 51
    • 1242314311 scopus 로고    scopus 로고
    • The effects of peripheral vagal nerve stimulation at a memory-modulating intensity on norepinephrine output in the basolateral amygdala
    • Hassert D.L., Miyashita T., Williams C.L. The effects of peripheral vagal nerve stimulation at a memory-modulating intensity on norepinephrine output in the basolateral amygdala. Behav. Neurosci. 2004, 118(1):79-88.
    • (2004) Behav. Neurosci. , vol.118 , Issue.1 , pp. 79-88
    • Hassert, D.L.1    Miyashita, T.2    Williams, C.L.3
  • 52
    • 84881166709 scopus 로고    scopus 로고
    • The auriculo-vagal afferent pathway and its role in seizure suppression in rats
    • He W., et al. The auriculo-vagal afferent pathway and its role in seizure suppression in rats. BMC Neurosci. 2013, 14:85.
    • (2013) BMC Neurosci. , vol.14 , pp. 85
    • He, W.1
  • 53
    • 0037167532 scopus 로고    scopus 로고
    • Therapeutic mechanisms of vagus nerve stimulation
    • Henry T.R. Therapeutic mechanisms of vagus nerve stimulation. Neurology 2002, 59(6 Suppl. 4):S3-S14.
    • (2002) Neurology , vol.59 , Issue.6 , pp. S3-S14
    • Henry, T.R.1
  • 54
    • 84870449048 scopus 로고    scopus 로고
    • Neuromodulation for treatment-resistant depression
    • Holtzheimer P.E., Mayberg H.S. Neuromodulation for treatment-resistant depression. F1000 Med. Rep. 2012, 4:22.
    • (2012) F1000 Med. Rep. , vol.4 , pp. 22
    • Holtzheimer, P.E.1    Mayberg, H.S.2
  • 55
    • 0029064557 scopus 로고
    • Neurotrophic factors: from structure-function studies to designing effective therapeutics
    • Ibanez C.F. Neurotrophic factors: from structure-function studies to designing effective therapeutics. Trends Biotechnol. 1995, 13(6):217-227.
    • (1995) Trends Biotechnol. , vol.13 , Issue.6 , pp. 217-227
    • Ibanez, C.F.1
  • 56
    • 33747037628 scopus 로고    scopus 로고
    • Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression
    • Jayatissa M.N., et al. Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Neuropsychopharmacology 2006, 31(11):2395-2404.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.11 , pp. 2395-2404
    • Jayatissa, M.N.1
  • 57
    • 38649136603 scopus 로고    scopus 로고
    • The number of granule cells in rat hippocampus is reduced after chronic mild stress and re-established after chronic escitalopram treatment
    • Jayatissa M.N., et al. The number of granule cells in rat hippocampus is reduced after chronic mild stress and re-established after chronic escitalopram treatment. Neuropharmacology 2008, 54(3):530-541.
    • (2008) Neuropharmacology , vol.54 , Issue.3 , pp. 530-541
    • Jayatissa, M.N.1
  • 58
    • 68949190909 scopus 로고    scopus 로고
    • Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats
    • Jayatissa M.N., et al. Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats. Brain Res. 2009, 1290:133-141.
    • (2009) Brain Res. , vol.1290 , pp. 133-141
    • Jayatissa, M.N.1
  • 59
    • 77249102054 scopus 로고    scopus 로고
    • Norepinephrine directly activates adult hippocampal precursors via beta3-adrenergic receptors
    • Jhaveri D.J., et al. Norepinephrine directly activates adult hippocampal precursors via beta3-adrenergic receptors. J. Neurosci. 2010, 30(7):2795-2806.
    • (2010) J. Neurosci. , vol.30 , Issue.7 , pp. 2795-2806
    • Jhaveri, D.J.1
  • 60
    • 0042572219 scopus 로고    scopus 로고
    • The complex epilepsy patient: intricacies of assessment and treatment
    • Kanner A.M. The complex epilepsy patient: intricacies of assessment and treatment. Epilepsia 2003, 44(Suppl. 5):3-8.
    • (2003) Epilepsia , vol.44 , pp. 3-8
    • Kanner, A.M.1
  • 61
    • 84869121865 scopus 로고    scopus 로고
    • Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders?
    • Kanner A.M. Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders?. Lancet Neurol. 2012, 11(12):1093-1102.
    • (2012) Lancet Neurol. , vol.11 , Issue.12 , pp. 1093-1102
    • Kanner, A.M.1
  • 62
    • 0037161382 scopus 로고    scopus 로고
    • Depression and epilepsy: how closely related are they?
    • Kanner A.M., Balabanov A. Depression and epilepsy: how closely related are they?. Neurology 2002, 58(8 Suppl. 5):S27-S39.
    • (2002) Neurology , vol.58 , Issue.8 , pp. S27-S39
    • Kanner, A.M.1    Balabanov, A.2
  • 63
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    • Karege F., et al. Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res. 2002, 109(2):143-148.
    • (2002) Psychiatry Res. , vol.109 , Issue.2 , pp. 143-148
    • Karege, F.1
  • 64
    • 18144416532 scopus 로고    scopus 로고
    • Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity
    • Karege F., et al. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol. Psychiatry 2005, 57(9):1068-1072.
    • (2005) Biol. Psychiatry , vol.57 , Issue.9 , pp. 1068-1072
    • Karege, F.1
  • 65
    • 0037341830 scopus 로고    scopus 로고
    • Epidemiology of women and depression
    • Kessler R.C. Epidemiology of women and depression. J. Affect. Disord. 2003, 74(1):5-13.
    • (2003) J. Affect. Disord. , vol.74 , Issue.1 , pp. 5-13
    • Kessler, R.C.1
  • 66
    • 0026038784 scopus 로고
    • Immunocytochemical localization of glutamate containing neurons in the ventrolateral medulla oblongata and the nucleus tractus solitarius of the rat
    • Kihara M., Kubo T. Immunocytochemical localization of glutamate containing neurons in the ventrolateral medulla oblongata and the nucleus tractus solitarius of the rat. J. Hirnforsch. 1991, 32(1):113-118.
    • (1991) J. Hirnforsch. , vol.32 , Issue.1 , pp. 113-118
    • Kihara, M.1    Kubo, T.2
  • 67
    • 84859436348 scopus 로고    scopus 로고
    • Vagus nerve stimulation has a positive effect on mood in patients with refractory epilepsy
    • Klinkenberg S., et al. Vagus nerve stimulation has a positive effect on mood in patients with refractory epilepsy. Clin. Neurol. Neurosurg. 2012, 114(4):336-340.
    • (2012) Clin. Neurol. Neurosurg. , vol.114 , Issue.4 , pp. 336-340
    • Klinkenberg, S.1
  • 68
    • 0032989539 scopus 로고    scopus 로고
    • The effect of acute tryptophan depletion and fenfluramine on quantitative EEG and mood in healthy male subjects
    • Knott V.J., et al. The effect of acute tryptophan depletion and fenfluramine on quantitative EEG and mood in healthy male subjects. Biol. Psychiatry 1999, 46(2):229-238.
    • (1999) Biol. Psychiatry , vol.46 , Issue.2 , pp. 229-238
    • Knott, V.J.1
  • 69
    • 79951851593 scopus 로고    scopus 로고
    • Chronic vagus nerve stimulation for treatment-resistant depression increases regional cerebral blood flow in the dorsolateral prefrontal cortex
    • Kosel M., et al. Chronic vagus nerve stimulation for treatment-resistant depression increases regional cerebral blood flow in the dorsolateral prefrontal cortex. Psychiatry Res. 2011, 191(3):153-159.
    • (2011) Psychiatry Res. , vol.191 , Issue.3 , pp. 153-159
    • Kosel, M.1
  • 70
    • 84870167065 scopus 로고    scopus 로고
    • Vagus nerve stimulation for epilepsy: a review of the peripheral mechanisms
    • Krahl S.E. Vagus nerve stimulation for epilepsy: a review of the peripheral mechanisms. Surg. Neurol. Int. 2012, 3(Suppl. 1):S47-S52.
    • (2012) Surg. Neurol. Int. , vol.3 , pp. S47-S52
    • Krahl, S.E.1
  • 71
    • 1542315615 scopus 로고    scopus 로고
    • Vagus nerve stimulation (VNS) is effective in a rat model of antidepressant action
    • Krahl S.E., et al. Vagus nerve stimulation (VNS) is effective in a rat model of antidepressant action. J. Psychiatr. Res. 2004, 38(3):237-240.
    • (2004) J. Psychiatr. Res. , vol.38 , Issue.3 , pp. 237-240
    • Krahl, S.E.1
  • 72
    • 0036833778 scopus 로고    scopus 로고
    • Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus
    • Kulkarni V.A., Jha S., Vaidya V.A. Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus. Eur. J. Neurosci. 2002, 16(10):2008-2012.
    • (2002) Eur. J. Neurosci. , vol.16 , Issue.10 , pp. 2008-2012
    • Kulkarni, V.A.1    Jha, S.2    Vaidya, V.A.3
  • 73
    • 84937515768 scopus 로고    scopus 로고
    • Acute vagal nerve stimulation lowers α2 adrenoceptor occupancy: possible mechanism of therapeutic action
    • (in press)
    • Landau A.M., Dyve S., Jakobsen S., Alstrup A.K.O., Gjedde A., Doudet D.J. Acute vagal nerve stimulation lowers α2 adrenoceptor occupancy: possible mechanism of therapeutic action. Brain Stimul. 2015, (in press).
    • (2015) Brain Stimul.
    • Landau, A.M.1    Dyve, S.2    Jakobsen, S.3    Alstrup, A.K.O.4    Gjedde, A.5    Doudet, D.J.6
  • 74
    • 0018134765 scopus 로고
    • Serotonin nerve terminals in the locus coeruleus of adult rat: a radioautographic study
    • Leger L., Descarries L. Serotonin nerve terminals in the locus coeruleus of adult rat: a radioautographic study. Brain Res. 1978, 145(1):1-13.
    • (1978) Brain Res. , vol.145 , Issue.1 , pp. 1-13
    • Leger, L.1    Descarries, L.2
  • 75
    • 21844442859 scopus 로고    scopus 로고
    • Offer and demand: proliferation and survival of neurons in the dentate gyrus
    • Lehmann K., Butz M., Teuchert-Noodt G. Offer and demand: proliferation and survival of neurons in the dentate gyrus. Eur. J. Neurosci. 2005, 21(12):3205-3216.
    • (2005) Eur. J. Neurosci. , vol.21 , Issue.12 , pp. 3205-3216
    • Lehmann, K.1    Butz, M.2    Teuchert-Noodt, G.3
  • 76
    • 0031724548 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors depress vagal and aortic baroreceptor signal transmission in the NTS
    • Liu Z., Chen C.Y., Bonham A.C. Metabotropic glutamate receptors depress vagal and aortic baroreceptor signal transmission in the NTS. Am. J. Physiol. 1998, 275(5 Pt 2):H1682-H1694.
    • (1998) Am. J. Physiol. , vol.275 , Issue.5 Pt 2 , pp. H1682-H1694
    • Liu, Z.1    Chen, C.Y.2    Bonham, A.C.3
  • 77
    • 0018836842 scopus 로고
    • Noradrenergic innervation of the adult rat hippocampal formation
    • Loy R., et al. Noradrenergic innervation of the adult rat hippocampal formation. J. Comp. Neurol. 1980, 189(4):699-710.
    • (1980) J. Comp. Neurol. , vol.189 , Issue.4 , pp. 699-710
    • Loy, R.1
  • 78
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg J.E., et al. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 2000, 20(24):9104-9110.
    • (2000) J. Neurosci. , vol.20 , Issue.24 , pp. 9104-9110
    • Malberg, J.E.1
  • 79
    • 0036239580 scopus 로고    scopus 로고
    • Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons
    • Mallei A., Shi B., Mocchetti I. Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons. Mol. Pharmacol. 2002, 61(5):1017-1024.
    • (2002) Mol. Pharmacol. , vol.61 , Issue.5 , pp. 1017-1024
    • Mallei, A.1    Shi, B.2    Mocchetti, I.3
  • 80
    • 70149083277 scopus 로고    scopus 로고
    • Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation
    • Manta S., et al. Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. J. Psychiatry Neurosci. 2009, 34(4):272-280.
    • (2009) J. Psychiatry Neurosci. , vol.34 , Issue.4 , pp. 272-280
    • Manta, S.1
  • 81
    • 84871919098 scopus 로고    scopus 로고
    • Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems
    • Manta S., et al. Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems. Int. J. Neuropsychopharmacol. 2012, 1-12.
    • (2012) Int. J. Neuropsychopharmacol. , pp. 1-12
    • Manta, S.1
  • 82
    • 84875926850 scopus 로고    scopus 로고
    • Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems
    • Manta S., et al. Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems. Int. J. Neuropsychopharmacol. 2013, 16(2):459-470.
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , Issue.2 , pp. 459-470
    • Manta, S.1
  • 83
    • 0037084471 scopus 로고    scopus 로고
    • Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes
    • Marangell L.B., et al. Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes. Biol. Psychiatry 2002, 51(4):280-287.
    • (2002) Biol. Psychiatry , vol.51 , Issue.4 , pp. 280-287
    • Marangell, L.B.1
  • 84
    • 78650333768 scopus 로고    scopus 로고
    • A review of monoaminergic neuropsychopharmacology in zebrafish
    • Maximino C., Herculano A.M. A review of monoaminergic neuropsychopharmacology in zebrafish. Zebrafish 2010, 7(4):359-378.
    • (2010) Zebrafish , vol.7 , Issue.4 , pp. 359-378
    • Maximino, C.1    Herculano, A.M.2
  • 85
    • 0032912252 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity
    • McEwen B.S. Stress and hippocampal plasticity. Annu. Rev. Neurosci. 1999, 22:105-122.
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 105-122
    • McEwen, B.S.1
  • 86
    • 0029149157 scopus 로고
    • Proliferation, differentiation, and survival of rat sensory neuron precursors in vitro require specific trophic factors
    • Memberg S.P., Hall A.K. Proliferation, differentiation, and survival of rat sensory neuron precursors in vitro require specific trophic factors. Mol. Cell. Neurosci. 1995, 6(4):323-335.
    • (1995) Mol. Cell. Neurosci. , vol.6 , Issue.4 , pp. 323-335
    • Memberg, S.P.1    Hall, A.K.2
  • 87
    • 59149088408 scopus 로고    scopus 로고
    • Towards achieving remission in the treatment of depression
    • Mendlewicz J. Towards achieving remission in the treatment of depression. Dialogues Clin. Neurosci. 2008, 10(4):371-375.
    • (2008) Dialogues Clin. Neurosci. , vol.10 , Issue.4 , pp. 371-375
    • Mendlewicz, J.1
  • 88
    • 4644353199 scopus 로고    scopus 로고
    • The role of monoamines in the actions of established and "novel" antidepressant agents: a critical review
    • Millan M.J. The role of monoamines in the actions of established and "novel" antidepressant agents: a critical review. Eur. J. Pharmacol. 2004, 500(1-3):371-384.
    • (2004) Eur. J. Pharmacol. , vol.500 , Issue.1-3 , pp. 371-384
    • Millan, M.J.1
  • 89
    • 80955124144 scopus 로고    scopus 로고
    • The importance of norepinephrine in depression
    • Moret C., Briley M. The importance of norepinephrine in depression. Neuropsychiatr. Dis. Treat. 2011, 7(Suppl. 1):9-13.
    • (2011) Neuropsychiatr. Dis. Treat. , vol.7 , pp. 9-13
    • Moret, C.1    Briley, M.2
  • 90
    • 84883560846 scopus 로고    scopus 로고
    • The effects of stimulation parameters on clinical outcomes in patients with vagus nerve stimulation implants with major depression
    • Muller H.H., et al. The effects of stimulation parameters on clinical outcomes in patients with vagus nerve stimulation implants with major depression. J. ECT 2013, 29(3):e40-e42.
    • (2013) J. ECT , vol.29 , Issue.3 , pp. e40-e42
    • Muller, H.H.1
  • 92
    • 26644452527 scopus 로고    scopus 로고
    • Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodes
    • Nahas Z., et al. Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodes. J. Clin. Psychiatry 2005, 66(9):1097-1104.
    • (2005) J. Clin. Psychiatry , vol.66 , Issue.9 , pp. 1097-1104
    • Nahas, Z.1
  • 93
    • 0036581252 scopus 로고    scopus 로고
    • Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein
    • Nakagawa S., et al. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J. Neurosci. 2002, 22(9):3673-3682.
    • (2002) J. Neurosci. , vol.22 , Issue.9 , pp. 3673-3682
    • Nakagawa, S.1
  • 94
    • 0028803065 scopus 로고
    • Regional induction of fos immunoreactivity in the brain by anticonvulsant stimulation of the vagus nerve
    • Naritoku D.K., Terry W.J., Helfert R.H. Regional induction of fos immunoreactivity in the brain by anticonvulsant stimulation of the vagus nerve. Epilepsy Res. 1995, 22(1):53-62.
    • (1995) Epilepsy Res. , vol.22 , Issue.1 , pp. 53-62
    • Naritoku, D.K.1    Terry, W.J.2    Helfert, R.H.3
  • 95
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M., Morinobu S., Duman R.S. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 1995, 15(11):7539-7547.
    • (1995) J. Neurosci. , vol.15 , Issue.11 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 96
    • 49749086886 scopus 로고    scopus 로고
    • Vagus nerve stimulation: 2-year outcomes for bipolar versus unipolar treatment-resistant depression
    • Nierenberg A.A., et al. Vagus nerve stimulation: 2-year outcomes for bipolar versus unipolar treatment-resistant depression. Biol. Psychiatry 2008, 64(6):455-460.
    • (2008) Biol. Psychiatry , vol.64 , Issue.6 , pp. 455-460
    • Nierenberg, A.A.1
  • 97
    • 0033216122 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS
    • Palmer T.D., et al. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J. Neurosci. 1999, 19(19):8487-8497.
    • (1999) J. Neurosci. , vol.19 , Issue.19 , pp. 8487-8497
    • Palmer, T.D.1
  • 98
    • 85052609924 scopus 로고    scopus 로고
    • Vagus nerve stimulation for depression: rationale, anatomical and physiological basis of efficacy and future prospects
    • Park M.C., et al. Vagus nerve stimulation for depression: rationale, anatomical and physiological basis of efficacy and future prospects. Acta Neurochir. Suppl. 2007, 97(Pt 2):407-416.
    • (2007) Acta Neurochir. Suppl. , vol.97 , Issue.Pt 2 , pp. 407-416
    • Park, M.C.1
  • 99
    • 0345540627 scopus 로고    scopus 로고
    • Autoregulation of serotonin neurons: role in antidepressant drug action
    • Pineyro G., Blier P. Autoregulation of serotonin neurons: role in antidepressant drug action. Pharmacol. Rev. 1999, 51(3):533-591.
    • (1999) Pharmacol. Rev. , vol.51 , Issue.3 , pp. 533-591
    • Pineyro, G.1    Blier, P.2
  • 100
    • 0017618768 scopus 로고
    • Depression: a new animal model sensitive to antidepressant treatments
    • Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 1977, 266(5604):730-732.
    • (1977) Nature , vol.266 , Issue.5604 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 101
  • 102
    • 79954420687 scopus 로고    scopus 로고
    • Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model
    • Raedt R., et al. Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model. J. Neurochem. 2011, 117(3):461-469.
    • (2011) J. Neurochem. , vol.117 , Issue.3 , pp. 461-469
    • Raedt, R.1
  • 103
    • 34447121927 scopus 로고    scopus 로고
    • Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brain
    • Rantamaki T., et al. Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brain. Neuropsychopharmacology 2007, 32(10):2152-2162.
    • (2007) Neuropsychopharmacology , vol.32 , Issue.10 , pp. 2152-2162
    • Rantamaki, T.1
  • 104
    • 56349152549 scopus 로고    scopus 로고
    • Effects of vagus nerve stimulation on rat hippocampal progenitor proliferation
    • Revesz D., et al. Effects of vagus nerve stimulation on rat hippocampal progenitor proliferation. Exp. Neurol. 2008, 214(2):259-265.
    • (2008) Exp. Neurol. , vol.214 , Issue.2 , pp. 259-265
    • Revesz, D.1
  • 105
    • 33745648114 scopus 로고    scopus 로고
    • The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells
    • Rizk P., et al. The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells. Neuropsychopharmacology 2006, 31(6):1146-1157.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.6 , pp. 1146-1157
    • Rizk, P.1
  • 106
    • 33750456540 scopus 로고    scopus 로고
    • Increased extracellular concentrations of norepinephrine in cortex and hippocampus following vagus nerve stimulation in the rat
    • Roosevelt R.W., et al. Increased extracellular concentrations of norepinephrine in cortex and hippocampus following vagus nerve stimulation in the rat. Brain Res. 2006, 1119(1):124-132.
    • (2006) Brain Res. , vol.1119 , Issue.1 , pp. 124-132
    • Roosevelt, R.W.1
  • 107
    • 79959371015 scopus 로고    scopus 로고
    • The chemical neuroanatomy of vagus nerve stimulation
    • Ruffoli R., et al. The chemical neuroanatomy of vagus nerve stimulation. J. Chem. Neuroanat. 2011, 42(4):288-296.
    • (2011) J. Chem. Neuroanat. , vol.42 , Issue.4 , pp. 288-296
    • Ruffoli, R.1
  • 108
    • 0033961645 scopus 로고    scopus 로고
    • Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study
    • Rush A.J., et al. Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study. Biol. Psychiatry 2000, 47(4):276-286.
    • (2000) Biol. Psychiatry , vol.47 , Issue.4 , pp. 276-286
    • Rush, A.J.1
  • 109
    • 24044436792 scopus 로고    scopus 로고
    • Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial
    • Rush A.J., et al. Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial. Biol. Psychiatry 2005, 58(5):347-354.
    • (2005) Biol. Psychiatry , vol.58 , Issue.5 , pp. 347-354
    • Rush, A.J.1
  • 110
    • 24044505312 scopus 로고    scopus 로고
    • Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study
    • Rush A.J., et al. Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study. Biol. Psychiatry 2005, 58(5):355-363.
    • (2005) Biol. Psychiatry , vol.58 , Issue.5 , pp. 355-363
    • Rush, A.J.1
  • 111
    • 0037218768 scopus 로고    scopus 로고
    • Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects
    • Saarelainen T., et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J. Neurosci. 2003, 23(1):349-357.
    • (2003) J. Neurosci. , vol.23 , Issue.1 , pp. 349-357
    • Saarelainen, T.1
  • 112
    • 0034784012 scopus 로고    scopus 로고
    • Vagus nerve stimulation (VNS) for treatment-resistant depression: efficacy, side effects, and predictors of outcome
    • Sackeim H.A., et al. Vagus nerve stimulation (VNS) for treatment-resistant depression: efficacy, side effects, and predictors of outcome. Neuropsychopharmacology 2001, 25(5):713-728.
    • (2001) Neuropsychopharmacology , vol.25 , Issue.5 , pp. 713-728
    • Sackeim, H.A.1
  • 113
    • 34548348778 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis in depression
    • Sahay A., Hen R. Adult hippocampal neurogenesis in depression. Nat. Neurosci. 2007, 10(9):1110-1115.
    • (2007) Nat. Neurosci. , vol.10 , Issue.9 , pp. 1110-1115
    • Sahay, A.1    Hen, R.2
  • 114
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003, 301(5634):805-809.
    • (2003) Science , vol.301 , Issue.5634 , pp. 805-809
    • Santarelli, L.1
  • 115
    • 41649085179 scopus 로고    scopus 로고
    • Vagus nerve stimulation for depression: efficacy and safety in a European study
    • Schlaepfer T.E., et al. Vagus nerve stimulation for depression: efficacy and safety in a European study. Psychol. Med. 2008, 38(5):651-661.
    • (2008) Psychol. Med. , vol.38 , Issue.5 , pp. 651-661
    • Schlaepfer, T.E.1
  • 116
    • 0029862949 scopus 로고    scopus 로고
    • Hippocampal atrophy in recurrent major depression
    • Sheline Y.I., et al. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. U. S. A. 1996, 93(9):3908-3913.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.9 , pp. 3908-3913
    • Sheline, Y.I.1
  • 117
    • 0038771149 scopus 로고    scopus 로고
    • Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants
    • Shimizu E., et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol. Psychiatry 2003, 54(1):70-75.
    • (2003) Biol. Psychiatry , vol.54 , Issue.1 , pp. 70-75
    • Shimizu, E.1
  • 118
    • 84861065549 scopus 로고    scopus 로고
    • Using the rat forced swim test to assess antidepressant-like activity in rodents
    • Slattery D.A., Cryan J.F. Using the rat forced swim test to assess antidepressant-like activity in rodents. Nat. Protoc. 2012, 7(6):1009-1014.
    • (2012) Nat. Protoc. , vol.7 , Issue.6 , pp. 1009-1014
    • Slattery, D.A.1    Cryan, J.F.2
  • 119
    • 0034619441 scopus 로고    scopus 로고
    • Erratum to "Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement"
    • Sousa N., et al. Erratum to "Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement". Neuroscience 2000, 101(2):483.
    • (2000) Neuroscience , vol.101 , Issue.2 , pp. 483
    • Sousa, N.1
  • 120
    • 0016593641 scopus 로고
    • Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine
    • Svensson T.H., Bunney B.S., Aghajanian G.K. Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine. Brain Res. 1975, 92(2):291-306.
    • (1975) Brain Res. , vol.92 , Issue.2 , pp. 291-306
    • Svensson, T.H.1    Bunney, B.S.2    Aghajanian, G.K.3
  • 121
    • 70449412255 scopus 로고    scopus 로고
    • Influence of vagotomy on monosynaptic transmission at second-order nucleus tractus solitarius synapses
    • Swartz J.B., Weinreich D. Influence of vagotomy on monosynaptic transmission at second-order nucleus tractus solitarius synapses. J. Neurophysiol. 2009, 102(5):2846-2855.
    • (2009) J. Neurophysiol. , vol.102 , Issue.5 , pp. 2846-2855
    • Swartz, J.B.1    Weinreich, D.2
  • 122
    • 0033610220 scopus 로고    scopus 로고
    • Efferent projections of the nucleus of the solitary tract to peri-locus coeruleus dendrites in rat brain: evidence for a monosynaptic pathway
    • Van Bockstaele E.J., Peoples J., Telegan P. Efferent projections of the nucleus of the solitary tract to peri-locus coeruleus dendrites in rat brain: evidence for a monosynaptic pathway. J. Comp. Neurol. 1999, 412(3):410-428.
    • (1999) J. Comp. Neurol. , vol.412 , Issue.3 , pp. 410-428
    • Van Bockstaele, E.J.1    Peoples, J.2    Telegan, P.3
  • 123
    • 0036428828 scopus 로고    scopus 로고
    • Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume
    • van der Hart M.G., et al. Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume. Mol. Psychiatry 2002, 7(9):933-941.
    • (2002) Mol. Psychiatry , vol.7 , Issue.9 , pp. 933-941
    • van der Hart, M.G.1
  • 124
    • 0021023465 scopus 로고
    • Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices
    • Vandermaelen C.P., Aghajanian G.K. Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices. Brain Res. 1983, 289(1-2):109-119.
    • (1983) Brain Res. , vol.289 , Issue.1-2 , pp. 109-119
    • Vandermaelen, C.P.1    Aghajanian, G.K.2
  • 125
    • 0142103727 scopus 로고    scopus 로고
    • Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder
    • Vermetten E., et al. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biol. Psychiatry 2003, 54(7):693-702.
    • (2003) Biol. Psychiatry , vol.54 , Issue.7 , pp. 693-702
    • Vermetten, E.1
  • 126
    • 0036703905 scopus 로고    scopus 로고
    • Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons
    • Vyas A., et al. Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J. Neurosci. 2002, 22(15):6810-6818.
    • (2002) J. Neurosci. , vol.22 , Issue.15 , pp. 6810-6818
    • Vyas, A.1
  • 127
    • 84877287517 scopus 로고    scopus 로고
    • The neural plasticity theory of depression: assessing the roles of adult neurogenesis and PSA-NCAM within the hippocampus
    • Wainwright S.R., Galea L.A. The neural plasticity theory of depression: assessing the roles of adult neurogenesis and PSA-NCAM within the hippocampus. Neural Plast. 2013, 2013:805497.
    • (2013) Neural Plast. , vol.2013 , pp. 805497
    • Wainwright, S.R.1    Galea, L.A.2
  • 128
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • Wong M.L., Licinio J. Research and treatment approaches to depression. Nat. Rev. Neurosci. 2001, 2(5):343-351.
    • (2001) Nat. Rev. Neurosci. , vol.2 , Issue.5 , pp. 343-351
    • Wong, M.L.1    Licinio, J.2
  • 129
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao C., Deng W., Gage F.H. Mechanisms and functional implications of adult neurogenesis. Cell 2008, 132(4):645-660.
    • (2008) Cell , vol.132 , Issue.4 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3
  • 130
    • 33847283622 scopus 로고    scopus 로고
    • Vagus nerve stimulation potentiates hippocampal LTP in freely-moving rats
    • Zuo Y., Smith D.C., Jensen R.A. Vagus nerve stimulation potentiates hippocampal LTP in freely-moving rats. Physiol. Behav. 2007, 90(4):583-589.
    • (2007) Physiol. Behav. , vol.90 , Issue.4 , pp. 583-589
    • Zuo, Y.1    Smith, D.C.2    Jensen, R.A.3


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