Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells

Frontiers in Pharmacology

Volumn 6, Issue OCT, 2015, Pages

  Dong, Hongli ^a   Carlton, Michael E ^a,c   Lerner, Adam ^b   Epstein, Paul M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b BOSTON MEDICAL CENTER   (United States)

^c HARTFORD HOSPITAL   (United States)

Author keywords

Bad; Bim; cAMP signaling; Glucocorticoid receptors; Glucocorticoid signaling; Leukemia; Multiple myeloma; Phosphodiesterases

Indexed keywords

BIM PROTEIN; CYCLIC AMP; FORSKOLIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR ALPHA 1A3; GLUCOCORTICOID RECEPTOR ALPHA 1B; GLUCOCORTICOID RECEPTOR ALPHA 1C; PROTEIN BAD; ROLIPRAM; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; CODON; CONTROLLED STUDY; HORMONE BINDING; HUMAN; HUMAN CELL; LEUKEMIA CELL; MULTIPLE MYELOMA; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 84947248624     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00230     Document Type: Article

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