Curcumin Enhanced Busulfan-Induced Apoptosis through Downregulating the Expression of Survivin in Leukemia Stem-Like KG1a Cells

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Weng, Guangyang ^a   Zeng, Yingjian ^b   Huang, Jingya ^c   Fan, Jiaxin ^b   Guo, Kunyuan ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Affiliated Jiangmen Traditional Chinese Medicine Hospital of Ji nan University   (China)

^c Shenzhen Municipal Hospital of Traditional Chinese Medicine   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CURCUMIN; LIPOCORTIN 5; SURVIVIN; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; HL 60 CELL LINE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MTT ASSAY; PROPIDIUM IODIDE ASSAY; PROTEIN EXPRESSION; STEM CELL; CANCER STEM CELL; CELL PROLIFERATION; DOWN REGULATION; DRUG EFFECTS; DRUG POTENTIATION; GENETICS; HL-60 CELL LINE; LEUKEMIA, MYELOID, ACUTE; TUMOR CELL LINE;

APOPTOSIS; BUSULFAN; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; DOWN-REGULATION; DRUG SYNERGISM; HL-60 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LEUKEMIA, MYELOID, ACUTE; NEOPLASTIC STEM CELLS;

EID: 84947222096     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/630397     Document Type: Article

References (56)

1. B. K. Hamilton and E. A. Copelan, "Concise review: the role of hematopoietic stem cell transplantation in the treatment of acutemyeloid leukemia, " StemCells, vol. 30, no. 8, pp. 1581-1586, 2012.
2. G. L. Phillips, "Allogeneic hematopoietic stem cell transplantation (HSCT) for high-risk acute myeloid leukemia (AML)/myelodysplastic syndrome (MDS): howcanwe improve outcomes in the near future?" Leukemia Research, vol. 36, no. 12, pp. 1490-1495, 2012.
3. A. Sureda, M. I. B. Pereira, and P. Dreger, "The role of hematopoietic stem cell transplantation in the treatment of relapsed/refractory Hodgkin's lymphoma, " Current Opinion in Oncology, vol. 24, no. 6, pp. 727-732, 2012.
4. E. D. Thomas, "A review of the results of human marrow transplantation in Seattle, " Nihon Ketsueki Gakkai Zasshi, vol. 40, pp. 863-872, 1977.
5. S. Z. Pavletic, S. Kumar, M.Mohty et al., "NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the epidemiology and natural history of relapse following allogeneic cell transplantation, " Biology of Blood and Marrow Transplantation, vol. 16, no. 7, pp. 871-890, 2010.
6. S. Yoshihara, T. Ando, and H. Ogawa, "Extramedullary relapse of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation: an easily overlooked but significant pattern of relapse, " Biology of Blood andMarrow Transplantation, vol. 18, no. 12, pp. 1800-1807, 2012.
7. M. L. Linenberger, T. Hong, D. Flowers et al., "Multidrugresistance phenotype and clinical responses to gemtuzumab ozogamicin, " Blood, vol. 98, no. 4, pp. 988-994, 2001.
8. M. Dean, T. Fojo, and S. Bates, "Tumour stem cells and drug resistance, " Nature Reviews Cancer, vol. 5, no. 4, pp. 275-284, 2005.
9. S. Pei and C. T. Jordan, "How close are we to targeting the leukemia stem cell?" Best Practice and Research: Clinical Haematology, vol. 25, no. 4, pp. 415-418, 2012.
10. T. Lapidot, C. Sirard, J. Vormoor et al., "A cell initiating human acutemyeloid leukaemia after transplantation into SCID mice, " Nature, vol. 367, no. 6464, pp. 645-648, 1994.
11. D. Fuchs, V. Daniel, M. Sadeghi, G. Opelz, and C. Naujokat, "Salinomycin overcomes ABC transporter-mediatedmultidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells, " Biochemical and Biophysical Research Communications, vol. 394, no. 4, pp. 1098-1104, 2010.
12. M. She, X. Niu, X. Chen et al., "Resistance of leukemic stemlike cells in AML cell line KG1a to natural killer cell-mediated cytotoxicity, " Cancer Letters, vol. 318, no. 2, pp. 173-179, 2012.
13. M. Mohty, F. Malard, D. Blaise et al., "Reduced-Toxicity conditioning with fludarabine, once-daily intravenous busulfan, and antithymocyte globulins prior to allogeneic stem cell transplantation: results of a multicenter prospective phase 2 trial, " Cancer, vol. 121, no. 4, pp. 562-569, 2015.
14. S. Almog, D. Kurnik, A. Shimoni et al., "Linearity and stability of intravenous busulfan pharmacokinetics and the role of glutathione in busulfan elimination, " Biology of Blood and Marrow Transplantation, vol. 17, no. 1, pp. 117-123, 2011.
15. Y. Jiao, J. T. Wilkinson, X. Di et al., "Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator, " Blood, vol. 113, no. 2, pp. 462-469, 2009.
16. B. van't Land, N. M. A. Blijlevens, J. Marteijn et al., "Role of curcumin and the inhibition of NF-KB in the onset of chemotherapy-induced mucosal barrier injury, " Leukemia, vol. 18, no. 2, pp. 276-284, 2004.
17. Y. Li and T. Zhang, "Targeting cancer stem cells by curcumin and clinical applications, " Cancer Letters, vol. 346, no. 2, pp. 197-205, 2014.
18. A. Goel and B. B. Aggarwal, "Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs, " Nutrition and Cancer, vol. 62, no. 7, pp. 919-930, 2010.
19. A. H. Rahmani, M. A. Al Zohairy, S. M. Aly, and M. A. Khan, "Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways, " BioMed Research International, vol. 2014, Article ID 761608, 15 pages, 2014.
20. M. M.Ho, D. E.Hogge, and V. Ling, "MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acutemyeloid leukemia, " ExperimentalHematology, vol. 36, no. 4, pp. 433-442, 2008.
21. G.-M. Zou, "Cancer stem cells in leukemia, recent advances, " Journal of Cellular Physiology, vol. 213, no. 2, pp. 440-444, 2007.
22. L. Ruggeri, A.Mancusi, M. Capanni et al., "Donor natural killer cell allorecognition ofmissing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value, " Blood, vol. 110, no. 1, pp. 433-440, 2007.
23. M. C. Stubbs and S. A. Armstrong, "Therapeutic implications of leukemia stem cell development, " Clinical Cancer Research, vol. 13, no. 12, pp. 3439-3442, 2007.
24. D. Bonnet and J. E. Dick, "Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell, " Nature Medicine, vol. 3, no. 7, pp. 730-737, 1997.
25. J. M. Gerber, B. D. Smith, B. Ngwang et al., "A clinically relevant population of leukemic CD34+CD38-cells in acute myeloid leukemia, " Blood, vol. 119, no. 15, pp. 3571-3577, 2012.
26. L.Hu, D. Cao, Y. Li, Y.He, and K. Guo, "Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors, " Cancer Biology and Therapy, vol. 13, no. 7, pp. 516-526, 2012.
27. Y. Sánchez, G. P. Simón, E. Calviño, E. de Blas, and P. Aller, "Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in humanmyeloid leukemia cell lines, " Journal of Pharmacology and Experimental Therapeutics, vol. 335, no. 1, pp. 114-123, 2010.
28. Y.-K. Kwon, J.-M. Jun, S.-W. Shin, J.-W. Cho, and S.-I. Suh, "Curcumin decreases cell proliferation rates through BTG2-mediated cyclin D1 down-regulation in U937 cells, " International Journal of Oncology, vol. 26, no. 6, pp. 1597-1603, 2005.
29. S. Derochette, T. Franck, A. Mouithys-Mickalad, G. Deby-Dupont, P. Neven, and D. Serteyn, "Intra-And extracellular antioxidant capacities of the new water-soluble form of curcumin (NDS27) on stimulated neutrophils and HL-60 cells, " Chemico-Biological Interactions, vol. 201, no. 1-3, pp. 49-57, 2013.
30. J.-C. Wu, C.-S. Lai, V. Badmaev, K. Nagabhushanam, C.-T. Ho, and M.-H. Pan, "Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR andMAPKsignaling pathways in human leukemia HL-60 cells, " Molecular Nutrition and Food Research, vol. 55, no. 11, pp. 1646-1654, 2011.
31. T. Zhou, L. Ye, Y. Bai et al., "Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog, " PLoS ONE, vol. 9, Article IDe107876, 2014.
32. C. Kantara, M. O'Connell, S. Sarkar, S. Moya, R. Ullrich, and P. Singh, "Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA, " Cancer Research, vol. 74, no. 9, pp. 2487-2498, 2014.
33. M. S. Charpentier, R. A.Whipple, M. I. Vitolo et al., "Curcumin targets breast cancer stem-like cells with microtentacles that persist in mammospheres and promote reattachment, " Cancer Research, vol. 74, no. 4, pp. 1250-1260, 2014.
34. P. Anand, C. Sundaram, S. Jhurani, A. B. Kunnumakkara, and B. B. Aggarwal, "Curcumin and cancer: an 'old-Age' disease with an 'age-old' solution, " Cancer Letters, vol. 267, no. 1, pp. 133-164, 2008.
35. J. Park, V.Ayyappan, E.-K. Bae et al., "Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells, " Molecular Oncology, vol. 2, no. 4, pp. 317-326, 2008.
36. Y. Yu, S. S. Kanwar, B. B. Patel, J. Nautiyal, F. H. Sarkar, and A. P. N. Majumdar, "Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX, " Translational Oncology, vol. 2, no. 4, pp. 321-328, 2009.
37. K. Srimuangwong, C. Tocharus, J. Tocharus, A. Suksamrarn, and P. Y. Chintana, "Effects of hexahydrocurcumin in combination with 5-fuorouracil on dimethylhydrazine-induced colon cancer in rats, "World Journal of Gastroenterology, vol. 18, no. 47, pp. 6951-6959, 2012.
38. F. Faĩo-Flores, J. A. Q. Suarez, P. C. Pardi, and D. A. Maria, "DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1, 4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment, " Tumor Biology, vol. 33, no. 3, pp. 775-785, 2012.
39. X.-Y. Zhang, Q.-X. Bai, G.-S. Huang, H. Zhao, J.-J. Chen, and L.-J. Yang, "Effect of curcumin in combination with bortezomib on proliferation and apoptosis of human multiple myeloma cell line H929 and its mechanism, "Zhongguo Shi YanXue Ye XueZa Zhi, vol. 19, no. 3, pp. 684-688, 2011.
40. T. Nakane, H. Nakamae, H. Koh et al., "Reduced-intensity conditioning by fludarabine/busulfan without additional irradiation or T-cell depletion leads to low non-relapsemortality in unrelated bone marrow transplantation, " International Journal of Hematology, vol. 93, no. 4, pp. 509-516, 2011.
41. J.-Y. Wang, P. Yu, S. Chen et al., "Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction, "MolecularOncology, vol. 7, no. 5, pp. 907-916, 2013.
42. U. Testa, "Leukemia stem cells, " Annals of Hematology, vol. 90, no. 3, pp. 245-271, 2011.
43. M. Sehl, H. Zhou, J. S. Sinsheimer, and K. L. Lange, "Extinction models for cancer stem cell therapy, " Mathematical Biosciences, vol. 234, no. 2, pp. 132-146, 2011.
44. S. W. Lane, D. T. Scadden, and D. G. Gilliland, "The leukemic stem cell niche: current concepts and therapeutic opportunities, " Blood, vol. 114, no. 6, pp. 1150-1157, 2009.
45. E. C. Zeestraten, A. Benard, M. S. Reimers et al., "Theprognostic value of the apoptosis pathway in colorectal cancer: a review of the literature on biomarkers identified by immunohistochemistry, " Biomarkers in Cancer, vol. 5, pp. 13-29, 2013.
46. B.P.Eckelman, G. S. Salvesen, and F. L. Scott, "Human inhibitor of apoptosis proteins:why XIAP is the black sheep of the family, " EMBO Reports, vol. 7, no. 10, pp. 988-994, 2006.
47. Y. E. Choi, M. Butterworth, S. Malladi, C. S. Duckett, G. M. Cohen, and S. B. Bratton, "The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing, " The Journal of Biological Chemistry, vol. 284, no. 19, pp. 12772-12782, 2009.
48. A. M. Verhagen, J. Silke, P. G. Ekert et al., "HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins, " The Journal of Biological Chemistry, vol. 277, no. 1, pp. 445-454, 2002.
49. L. Miguel Martins, I. Iaccarino, T. Tenev et al., "The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a Reaper-like motif, " Journal of Biological Chemistry, vol. 277, no. 1, pp. 439-444, 2002.
50. K. Sekine, Y. Hao, Y. Suzuki, R. Takahashi, T. Tsuruo, and M. Naito, "HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells, " Biochemical and Biophysical Research Communications, vol. 330, no. 1, pp. 279-285, 2005.
51. C. H. A. Cheung, C.-C. Huang, F.-Y. Tsai et al., "Survivin-biology and potential as a therapeutic target in oncology, " OncoTargets andTherapy, vol. 6, pp. 1453-1462, 2013.
52. L. Bongiovanni, F. Di Diodoro, S. L. Della, and C. Brachelente, "On the role of survivin as a stem cell biomarker of canine hair follicle and related tumours, " Veterinary Dermatology, vol. 25, no. 2, pp. 138-141, e39-e40, 2014.
53. J. R. Kanwar, G. Mahidhara, K. Roy et al., "Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calciumand zinc, " Nanomedicine, vol. 10, no. 1, pp. 35-55, 2015.
54. S. Fukuda, M. Abe, C. Onishi et al., "Survivin selectively modulates genes deregulated in human leukemia stem cells, " Journal of Oncology, vol. 2011, Article ID 946936, 14 pages, 2011.
55. R. Gedaly, R. Galuppo, M. F. Daily et al., "Targeting the Wnt/beta-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lineswith FH535, " PLoSONE, vol. 9, no. 6, Article IDe99272, 2014.
56. R. Galuppo, E. Maynard, M. Shah et al., "Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/beta-catenin pathways, " Anticancer Research, vol. 34, pp. 1709-1713, 2014.