Reduced gut acidity induces an obese-like phenotype in drosophila melanogaster and in mice

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Lin, Wei Sheng ^a,e   Huang, Cheng Wen ^a,f   Song, You Sheng ^b   Yen, Jui Hung ^c   Kuo, Ping Chang ^c   Yeh, Sheng Rong ^a   Lin, Hung Yu ^f   Fu, Tsai Feng ^d   Wu, Ming Shiang ^e   Wang, Horng Dar ^f   Wang, Pei Yu ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL CHENGCHI UNIVERSITY   (Taiwan)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL CHI NAN UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; ACETAZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; DROSOPHILA PROTEIN; LANSOPRAZOLE; PROTON PUMP INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACIDITY; ADULT; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HOMOZYGOTE; IMAGO; INTRON; LIFESPAN; LIPID STORAGE; MALE; MIDGUT; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; SURVIVAL RATE; WEIGHT GAIN; ACID BASE BALANCE; ANIMAL; DRUG EFFECTS; GASTROINTESTINAL TRACT; GENETICS; METABOLISM; STOMACH PH;

ACETAZOLAMIDE; ACID-BASE EQUILIBRIUM; ANIMALS; CARBONIC ANHYDRASE INHIBITORS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GASTRIC ACIDITY DETERMINATION; GASTROINTESTINAL TRACT; LANSOPRAZOLE; MICE; OBESITY; PHENOTYPE; PROTON PUMP INHIBITORS; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84947205154     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0139722     Document Type: Article

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