메뉴 건너뛰기




Volumn 9, Issue 1, 2011, Pages

Lansoprazole as a rescue agent in chemoresistant tumors: A phase I/II study in companion animals with spontaneously occurring tumors

Author keywords

Carboplatin; Chemotherapy; Lansoprazole; Mitoxantrone; Proton pump

Indexed keywords

ANTIBIOTIC AGENT; ASPARAGINASE; CARBOPLATIN; CHLORAMBUCIL; CHLORMETHINE; CHLORPHENIRAMINE; CLODRONIC ACID; CYCLOPHOSPHAMIDE; DOXORUBICIN; LANSOPRAZOLE; METOCLOPRAMIDE; MITOXANTRONE; PIROXICAM; PREDNISOLONE; PREDNISONE; PROBIOTIC AGENT; PROCARBAZINE; PROTON PUMP INHIBITOR; RANITIDINE; SUCRALFATE; VINCRISTINE; 2 [[(2 PYRIDYL)METHYL]SULFINYL]BENZIMIDAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT;

EID: 84455173776     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-9-221     Document Type: Article
Times cited : (77)

References (50)
  • 1
    • 0030839304 scopus 로고    scopus 로고
    • The vacuolar H+-ATPase: a universal proton pump of eukaryotes
    • 1218484, 9210392
    • Finbow ME, Harrison MA. The vacuolar H+-ATPase: a universal proton pump of eukaryotes. Biochem J 1997, 324:697-712. 1218484, 9210392.
    • (1997) Biochem J , vol.324 , pp. 697-712
    • Finbow, M.E.1    Harrison, M.A.2
  • 2
    • 35448946098 scopus 로고    scopus 로고
    • Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology
    • 10.1038/nrm2272, 17912264
    • Forgac M. Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. Nat Rev Mol Cell Biol 2007, 8:917-929. 10.1038/nrm2272, 17912264.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 917-929
    • Forgac, M.1
  • 4
    • 46049100082 scopus 로고    scopus 로고
    • Function, structure and regulation of the vacuolar (H+)-ATPases
    • 10.1016/j.abb.2008.03.025, 2543942, 18406336
    • Jefferies KC, Cipriano DJ, Forgac M. Function, structure and regulation of the vacuolar (H+)-ATPases. Arch Biochem Biophys 2008, 476:33-42. 10.1016/j.abb.2008.03.025, 2543942, 18406336.
    • (2008) Arch Biochem Biophys , vol.476 , pp. 33-42
    • Jefferies, K.C.1    Cipriano, D.J.2    Forgac, M.3
  • 5
    • 11844260070 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells
    • 10.1128/MCB.25.2.575-589.2005, 543406, 15632060
    • Sautin YY, Lu M, Gaugler A, Zhang L, Gluck SL. Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells. Mol Cell Biol 2005, 25:575-589. 10.1128/MCB.25.2.575-589.2005, 543406, 15632060.
    • (2005) Mol Cell Biol , vol.25 , pp. 575-589
    • Sautin, Y.Y.1    Lu, M.2    Gaugler, A.3    Zhang, L.4    Gluck, S.L.5
  • 6
    • 0037470438 scopus 로고    scopus 로고
    • Activation of lysosomal function during dendritic cell maturation
    • 10.1126/science.1080106, 12610307
    • Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. Activation of lysosomal function during dendritic cell maturation. Science 2003, 299:1400-1403. 10.1126/science.1080106, 12610307.
    • (2003) Science , vol.299 , pp. 1400-1403
    • Trombetta, E.S.1    Ebersold, M.2    Garrett, W.3    Pypaert, M.4    Mellman, I.5
  • 7
    • 0026781858 scopus 로고
    • A novel mechanism for regulation of vacuolar acidification
    • Feng Y, Forgac M. A novel mechanism for regulation of vacuolar acidification. J Biol Chem 1992, 267:19769-19772.
    • (1992) J Biol Chem , vol.267 , pp. 19769-19772
    • Feng, Y.1    Forgac, M.2
  • 8
    • 0026688602 scopus 로고
    • Cysteine 254 of the 73-kDa A subunit is responsible for inhibition of the coated vesicle (H+)-ATPase upon modification by sulfhydryl reagents
    • Feng Y, Forgac M. Cysteine 254 of the 73-kDa A subunit is responsible for inhibition of the coated vesicle (H+)-ATPase upon modification by sulfhydryl reagents. J Biol Chem 1992, 267:5817-5822.
    • (1992) J Biol Chem , vol.267 , pp. 5817-5822
    • Feng, Y.1    Forgac, M.2
  • 9
    • 0028319319 scopus 로고
    • Inhibition of vacuolar H(+)-ATPase by disulfide bond formation between cysteine 254 and cysteine 532 in subunit A
    • Feng Y, Forgac M. Inhibition of vacuolar H(+)-ATPase by disulfide bond formation between cysteine 254 and cysteine 532 in subunit A. J Biol Chem 1994, 269:13224-13230.
    • (1994) J Biol Chem , vol.269 , pp. 13224-13230
    • Feng, Y.1    Forgac, M.2
  • 10
    • 0033556401 scopus 로고    scopus 로고
    • The vacuolar H+-ATPase of clathrin-coated vesicles is reversibly inhibited by Snitrosoglutathione
    • Forgac M. The vacuolar H+-ATPase of clathrin-coated vesicles is reversibly inhibited by Snitrosoglutathione. J Biol Chem 1999, 274:301-1305.
    • (1999) J Biol Chem , vol.274 , pp. 301-1305
    • Forgac, M.1
  • 11
    • 0034698103 scopus 로고    scopus 로고
    • Subunit D (Vma8p) of the yeast vacuolar H+-ATPase plays a role in coupling of proton transport and ATP hydrolysis
    • 10.1074/jbc.M002983200, 10801866
    • Xu T, Forgac M. Subunit D (Vma8p) of the yeast vacuolar H+-ATPase plays a role in coupling of proton transport and ATP hydrolysis. J Biol Chem 2000, 275:22075-22081. 10.1074/jbc.M002983200, 10801866.
    • (2000) J Biol Chem , vol.275 , pp. 22075-22081
    • Xu, T.1    Forgac, M.2
  • 12
    • 0035861664 scopus 로고    scopus 로고
    • The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis
    • 10.1074/jbc.M108310200, 11592965
    • Kawasaki-Nishi S, Bowers K, Nishi T, Forgac M, Stevens TH. The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis. J Biol Chem 2001, 276:47411-47420. 10.1074/jbc.M108310200, 11592965.
    • (2001) J Biol Chem , vol.276 , pp. 47411-47420
    • Kawasaki-Nishi, S.1    Bowers, K.2    Nishi, T.3    Forgac, M.4    Stevens, T.H.5
  • 13
    • 0026657798 scopus 로고
    • Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials
    • Saitoh O, Wang WC, Lotan R, Fukuda M. Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J Biol Chem 1992, 267:5700-5711.
    • (1992) J Biol Chem , vol.267 , pp. 5700-5711
    • Saitoh, O.1    Wang, W.C.2    Lotan, R.3    Fukuda, M.4
  • 14
    • 0345791482 scopus 로고    scopus 로고
    • Extracellular acidification alters lysosomal trafficking in human breast cancer cells
    • 1502575, 14965446
    • Glunde K, Guggino SE, Solaiyappan M, Pathak AP, Ichikawa Y, Bhujwalla ZM. Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 2003, 5:533-545. 1502575, 14965446.
    • (2003) Neoplasia , vol.5 , pp. 533-545
    • Glunde, K.1    Guggino, S.E.2    Solaiyappan, M.3    Pathak, A.P.4    Ichikawa, Y.5    Bhujwalla, Z.M.6
  • 15
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • 10.1038/nrc1478, 15516961
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis?. Nat Rev Cancer 2004, 4:891-899. 10.1038/nrc1478, 15516961.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 16
    • 36349001899 scopus 로고    scopus 로고
    • Targeting vacuolar H+-ATPases as a new strategy against cancer
    • 10.1158/0008-5472.CAN-07-1805, 18006801
    • Fais S, De Milito A, You H, Qin W. Targeting vacuolar H+-ATPases as a new strategy against cancer. Cancer Res 2007, 67:10627-10630. 10.1158/0008-5472.CAN-07-1805, 18006801.
    • (2007) Cancer Res , vol.67 , pp. 10627-10630
    • Fais, S.1    De Milito, A.2    You, H.3    Qin, W.4
  • 17
    • 0036481562 scopus 로고    scopus 로고
    • The vacuolar (H+)-ATPases nature's most versatile proton pumps
    • 10.1038/nrm729, 11836511
    • Nishi T, Forgac M. The vacuolar (H+)-ATPases nature's most versatile proton pumps. Nat Rev Mol Cell Biol 2002, 3:94-103. 10.1038/nrm729, 11836511.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 94-103
    • Nishi, T.1    Forgac, M.2
  • 18
    • 0027373117 scopus 로고
    • Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells
    • Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells. Am J Physiol 1993, 265:1015-29.
    • (1993) Am J Physiol , vol.265 , pp. 1015-1029
    • Martinez-Zaguilan, R.1    Lynch, R.M.2    Martinez, G.M.3    Gillies, R.J.4
  • 19
    • 23044467723 scopus 로고    scopus 로고
    • The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump
    • 10.1158/0008-5472.CAN-04-3822, 16061667
    • Lu X, Qin W, Li J, Tan N, Pan D, Zhang H, Xie L, Yao G, Shu H, Yao M, Wan D, Gu J, Yang S. The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump. Cancer Res 2005, 65:6843-6849. 10.1158/0008-5472.CAN-04-3822, 16061667.
    • (2005) Cancer Res , vol.65 , pp. 6843-6849
    • Lu, X.1    Qin, W.2    Li, J.3    Tan, N.4    Pan, D.5    Zhang, H.6    Xie, L.7    Yao, G.8    Shu, H.9    Yao, M.10    Wan, D.11    Gu, J.12    Yang, S.13
  • 20
    • 0141786825 scopus 로고    scopus 로고
    • Tumor acidity, ione trapping and chemotherapeutics I. Acid pH effects the distribution of chemotherapeutic agents in vitro
    • 10.1016/S0006-2952(03)00467-2, 14505800
    • Mahoney BP, Raghunand N, Bagget B, Gillies RJ. Tumor acidity, ione trapping and chemotherapeutics I. Acid pH effects the distribution of chemotherapeutic agents in vitro. Biochem Pharmacol 2003, 66:1207-1218. 10.1016/S0006-2952(03)00467-2, 14505800.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1207-1218
    • Mahoney, B.P.1    Raghunand, N.2    Bagget, B.3    Gillies, R.J.4
  • 21
    • 0028128073 scopus 로고
    • Intracellular Ph and the control of multidrug resistance
    • Simon S, Roy D, Schindler M. Intracellular Ph and the control of multidrug resistance. Proc Nat Acad Sci USA 1993, 91:1128-1132.
    • (1993) Proc Nat Acad Sci USA , vol.91 , pp. 1128-1132
    • Simon, S.1    Roy, D.2    Schindler, M.3
  • 22
    • 0141740718 scopus 로고    scopus 로고
    • Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents
    • Raghunand N, Mahoney BP, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents. BiochemPharmacol 2003, 66:1219-1229.
    • (2003) BiochemPharmacol , vol.66 , pp. 1219-1229
    • Raghunand, N.1    Mahoney, B.P.2    Gillies, R.J.3
  • 23
    • 0345040164 scopus 로고    scopus 로고
    • PH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines
    • 10.1016/S0006-2952(99)00022-2, 10796074
    • Martínez-Zaguilán R, Raghunand N, Lynch RM, Bellamy W, Martinez GM, Rojas B, Smith D, Dalton WS, Gillies RJ. pH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines. Biochem Pharmacol 1999, 57:1037-1046. 10.1016/S0006-2952(99)00022-2, 10796074.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1037-1046
    • Martínez-Zaguilán, R.1    Raghunand, N.2    Lynch, R.M.3    Bellamy, W.4    Martinez, G.M.5    Rojas, B.6    Smith, D.7    Dalton, W.S.8    Gillies, R.J.9
  • 24
    • 0345389967 scopus 로고    scopus 로고
    • PH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs
    • 10.1016/S0006-2952(99)00021-0, 10796075
    • Raghunand N, Martínez-Zaguilán R, Wright SH, Gillies RJ. pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. Biochem Pharmacol 1999, 57:1047-1058. 10.1016/S0006-2952(99)00021-0, 10796075.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1047-1058
    • Raghunand, N.1    Martínez-Zaguilán, R.2    Wright, S.H.3    Gillies, R.J.4
  • 25
    • 0029677414 scopus 로고    scopus 로고
    • Ultrastructural changes related to multidrug resistance in CEM cells: role of cytoplasmic vesicles in drug exclusion
    • Bobichon H, Colin M, Depierreux C, Liautaud-Roger F, Jardillier JC. Ultrastructural changes related to multidrug resistance in CEM cells: role of cytoplasmic vesicles in drug exclusion. J Exp Ther Oncol 1996, 1:49-61.
    • (1996) J Exp Ther Oncol , vol.1 , pp. 49-61
    • Bobichon, H.1    Colin, M.2    Depierreux, C.3    Liautaud-Roger, F.4    Jardillier, J.C.5
  • 30
    • 0042662895 scopus 로고    scopus 로고
    • Low pH enhances Sp1 DNA binding activity and interaction with TBP
    • 10.1093/nar/gkg487, 169877, 12888513
    • Torigoe T, Izumi H, Yoshida Y, Ishiguchi H, Okamoto T, Itoh H, Kohno K. Low pH enhances Sp1 DNA binding activity and interaction with TBP. Nucleic Acids Res 2003, 31:4523-4530. 10.1093/nar/gkg487, 169877, 12888513.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4523-4530
    • Torigoe, T.1    Izumi, H.2    Yoshida, Y.3    Ishiguchi, H.4    Okamoto, T.5    Itoh, H.6    Kohno, K.7
  • 32
    • 84882884013 scopus 로고    scopus 로고
    • Mast cell tumors
    • Philadelphia, PA: WB Saunders Co, Withrow SJ, MacEwen EG, 4
    • Thamm DH, Vail DM. Mast cell tumors. Small Animal Clinical Oncology 2007, 402-424. Philadelphia, PA: WB Saunders Co, Withrow SJ, MacEwen EG, 4.
    • (2007) Small Animal Clinical Oncology , pp. 402-424
    • Thamm, D.H.1    Vail, D.M.2
  • 33
    • 0031266167 scopus 로고    scopus 로고
    • Omeprazole in a dog with gastrinoma
    • 10.1111/j.1939-1676.1997.tb00485.x, 9470166
    • Brooks D, Watson GL. Omeprazole in a dog with gastrinoma. J Vet Intern Med 1997, 11:379-381. 10.1111/j.1939-1676.1997.tb00485.x, 9470166.
    • (1997) J Vet Intern Med , vol.11 , pp. 379-381
    • Brooks, D.1    Watson, G.L.2
  • 35
    • 33750289466 scopus 로고    scopus 로고
    • Canine gastrinoma: a case study and literature review of therapeutic options
    • 10.1080/00480169.2006.36705, 17028663
    • Hughes SM. Canine gastrinoma: a case study and literature review of therapeutic options. N Z Vet J 2006, 54:242-247. 10.1080/00480169.2006.36705, 17028663.
    • (2006) N Z Vet J , vol.54 , pp. 242-247
    • Hughes, S.M.1
  • 36
    • 84856050653 scopus 로고    scopus 로고
    • Gastrointestinal endocrine disease
    • Textbook of Veterinary Internal Medicine, Ettinger SJ, Feldman EC, Seventh, Saunders, St. Louis
    • Ward CR. Gastrointestinal endocrine disease. 2010, 1862-1865. Textbook of Veterinary Internal Medicine, Ettinger SJ, Feldman EC, Seventh, Saunders, St. Louis.
    • (2010) , pp. 1862-1865
    • Ward, C.R.1
  • 37
    • 0023785754 scopus 로고
    • The effect of lysosomotropic agents and secretory inhibitors on anthracycline retention and activity in multiple drug-resistant cells
    • Klohs WD, Steinkampf RW. The effect of lysosomotropic agents and secretory inhibitors on anthracycline retention and activity in multiple drug-resistant cells. Mol Pharmacol 1988, 34:180-185.
    • (1988) Mol Pharmacol , vol.34 , pp. 180-185
    • Klohs, W.D.1    Steinkampf, R.W.2
  • 38
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • 10.1073/pnas.91.9.3497, 43607, 7909602
    • Simon SM, Schindler M. Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA 1994, 91:3497-3504. 10.1073/pnas.91.9.3497, 43607, 7909602.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 39
    • 0029066357 scopus 로고
    • Gastric antisecretory activity of lansoprazole in different experimental models: comparison with omeprazole
    • 10.1016/0306-3623(94)00278-U, 7557245
    • Coruzzi G, Adami M, Bertaccini G. Gastric antisecretory activity of lansoprazole in different experimental models: comparison with omeprazole. Gen Pharmacol 1995, 26:1027-1032. 10.1016/0306-3623(94)00278-U, 7557245.
    • (1995) Gen Pharmacol , vol.26 , pp. 1027-1032
    • Coruzzi, G.1    Adami, M.2    Bertaccini, G.3
  • 40
    • 77951951499 scopus 로고    scopus 로고
    • Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy
    • 10.1186/1756-9966-29-44, 2876100, 20459683
    • Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy. J Exp Clin Cancer Res 2010, 29:44. 10.1186/1756-9966-29-44, 2876100, 20459683.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 44
    • Spugnini, E.P.1    Citro, G.2    Fais, S.3
  • 41
    • 32144456431 scopus 로고    scopus 로고
    • Acridine orange used for photodynamic therapy accumulates in malignantmusculoskeletal tumors depending on pH gradient
    • Matsubara T, Kusuzaki K, Matsumine A, Shintani K, Satonaka H, Uchida A. Acridine orange used for photodynamic therapy accumulates in malignantmusculoskeletal tumors depending on pH gradient. Anticancer Res 2006, 26:187-193.
    • (2006) Anticancer Res , vol.26 , pp. 187-193
    • Matsubara, T.1    Kusuzaki, K.2    Matsumine, A.3    Shintani, K.4    Satonaka, H.5    Uchida, A.6
  • 43
    • 77950501364 scopus 로고    scopus 로고
    • Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism
    • 10.1111/j.1365-2796.2010.02225.x, 20433578
    • Fais S. Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism. J Intern Med 2010, 267(5):515-25. 10.1111/j.1365-2796.2010.02225.x, 20433578.
    • (2010) J Intern Med , vol.267 , Issue.5 , pp. 515-525
    • Fais, S.1
  • 44
    • 84856063065 scopus 로고    scopus 로고
    • Cancer-related bone pain
    • Bonica's management of pain. Lippincott Williams & Wilkins, Ballantyne J, Fishman SM, Rathmell JP, 4
    • Abraham J, Ross E, Klickovich RJ. Cancer-related bone pain. 2009, 629-654. Bonica's management of pain. Lippincott Williams & Wilkins, Ballantyne J, Fishman SM, Rathmell JP, 4.
    • (2009) , pp. 629-654
    • Abraham, J.1    Ross, E.2    Klickovich, R.J.3
  • 45
    • 42949155409 scopus 로고    scopus 로고
    • Chronic metabolic acidosis may be the cause of cachexia: body fluid pH correction may be an effective therapy
    • 10.1016/j.mehy.2007.11.007, 18180110
    • Drochioiu G. Chronic metabolic acidosis may be the cause of cachexia: body fluid pH correction may be an effective therapy. Med Hypotheses 2008, 70:1167-73. 10.1016/j.mehy.2007.11.007, 18180110.
    • (2008) Med Hypotheses , vol.70 , pp. 1167-1173
    • Drochioiu, G.1
  • 46
    • 78649500338 scopus 로고    scopus 로고
    • Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCε pathway in dorsal root ganglion neurons
    • 10.1186/1744-8069-6-85, 3004845, 21118579
    • Pan HL, Zhang YQ, Zhao ZQ. Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCε pathway in dorsal root ganglion neurons. Mol Pain 2010, 6:85. 10.1186/1744-8069-6-85, 3004845, 21118579.
    • (2010) Mol Pain , vol.6 , pp. 85
    • Pan, H.L.1    Zhang, Y.Q.2    Zhao, Z.Q.3
  • 48
    • 0035425227 scopus 로고    scopus 로고
    • Biology of Osteoclast Activation in Cancer
    • Roodman GD. Biology of Osteoclast Activation in Cancer. J Clin Oncol 2001, 19:3562-3571.
    • (2001) J Clin Oncol , vol.19 , pp. 3562-3571
    • Roodman, G.D.1
  • 50
    • 33646100285 scopus 로고    scopus 로고
    • Oncology of companion animals as a model for humans: an overview of tumor histotypes
    • Porrello A, Cardelli P, Spugnini EP. Oncology of companion animals as a model for humans: an overview of tumor histotypes. J Exp Clin Cancer Res 2006, 25:97-106.
    • (2006) J Exp Clin Cancer Res , vol.25 , pp. 97-106
    • Porrello, A.1    Cardelli, P.2    Spugnini, E.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.