A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway

Tumor Biology

Volumn 36, Issue 9, 2015, Pages 7027-7034

  Das, Arabinda ^a   Miller, Rickey ^a   Lee, Philip ^a   Holden, Chrysanthe Alyssa ^a   Lindhorst, Scott M ^a   Jaboin, Jerry ^b   Vandergrift, William A ^a   Banik, Naren L ^a,c   Giglio, Pierre ^a,d   Varma, Abhay K ^a   Raizer, Jeffery J ^e   Patel, Sunil J ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Apoptosis; Catenin; Ginger; Lemon; Meningioma; Mushroom; Wnt

Indexed keywords

(6) GINGEROL; ANTINEOPLASTIC AGENT; BETA CATENIN; CASPASE 3; GANODERIC ACID A; GANODERIC ACID DM; GLYCOGEN SYNTHASE KINASE 3BETA; LIMONIN; PLANT MEDICINAL PRODUCT; PROTEIN BAX; PROTEIN BCL XL; PROTEIN MCL 1; TANGERITIN; TETRASPANIN; TSPAN12 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN; WNT5B PROTEIN; ZERUMBONE; 3,7-DIOXOLANOSTA-8,24-DIEN-26-OIC ACID; CATECHOL DERIVATIVE; FATTY ALCOHOL; FLAVONE DERIVATIVE; GINGEROL; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HEPTANOIC ACID DERIVATIVE; LANOSTEROL; LIMONOID; SESQUITERPENE; TANGERETIN; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CASPASE ASSAY; CELL VIABILITY ASSAY; CH157MN CELL LINE; CITRUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION ASSAY; DOWN REGULATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GINGER; HUMAN; HUMAN CELL; IN VITRO STUDY; IOMM LEE CELL LINE; MENINGIOMA; MTT ASSAY; MUSHROOM; NERVE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMISTRY; DNA FRAGMENTATION; DRUG EFFECTS; GENETICS; PATHOLOGY; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

APOPTOSIS; CATECHOLS; CELL LINE, TUMOR; DNA FRAGMENTATION; FATTY ALCOHOLS; FLAVONES; GLYCOGEN SYNTHASE KINASE 3; HEPTANOIC ACIDS; HUMANS; LANOSTEROL; LIMONINS; MENINGIOMA; SESQUITERPENES; TRITERPENES; WNT SIGNALING PATHWAY;

EID: 84947126469     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3388-0     Document Type: Article

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