Sph3 is a glycoside hydrolase required for the biosynthesis of galactosaminogalactan in aspergillus fumigatus

Journal of Biological Chemistry

Volumn 290, Issue 46, 2015, Pages 27438-27450

  Bamford, Natalie C ^a,b   Snarr, Brendan D ^c   Gravelat, Fabrice N ^c   Little, Dustin J ^a,b   Lee, Mark J ^c   Zacharias, Caitlin A ^c   Chabot, Josée C ^c   Geller, Alexander M ^c   Baptista, Stefanie D ^c   Baker, Perrin ^a   Robinson, Howard ^d   Howell, P Lynne ^a,b   Sheppard, Donald C ^c  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; ENCODING (SYMBOLS); ENZYME ACTIVITY; GENES; HYDROLASES; PROTEINS; SUGARS;

ACIDIC RESIDUES; ASPERGILLUS FUMIGATUS; ASPERGILLUS GENERA; EXOPOLYSACCHARIDES; GLYCOSIDE HYDROLASES; HYDROLYTIC ACTIVITIES; MORTALITY RATE; SEQUENCE ALIGNMENTS;

ASPERGILLUS;

ASPARTIC ACID; EXOPOLYSACCHARIDE; GALACTAN; GALACTOSAMINOGALACTAN; GLUTAMIC ACID; GLYCOSIDASE; GLYCOSIDE HYDROLASE 135; PROTEIN SPH3; RECOMBINANT PROTEIN; RECOMBINANT SPH3 PROTEIN; SPHERULIN 4; UNCLASSIFIED DRUG; COCCIDIOIDIN; FUNGAL PROTEIN; POLYSACCHARIDE; SPHERULIN;

ARTICLE; ASPERGILLUS CLAVATUS; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; FUNGAL VIRULENCE; GENE; GENE CLUSTER; GENE IDENTIFICATION; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SPH3 GENE; AMINO ACID SEQUENCE; CATALYSIS; CELL WALL; CHEMISTRY; CONSERVED SEQUENCE; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PATHOGENICITY; PHYSIOLOGY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ASPERGILLUS FUMIGATUS; CATALYSIS; CATALYTIC DOMAIN; CELL WALL; COCCIDIOIDIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; GLYCOSIDE HYDROLASES; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MUTATION; POLYSACCHARIDES; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT;

EID: 84946944902     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.679050     Document Type: Article

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