Glpx gene in mycobacterium tuberculosis is required for in vitro gluconeogenic growth and in vivo survival

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Gutka, Hiten J ^a,b   Wang, Yuehong ^a   Franzblau, Scott G ^a   Movahedzadeh, Farahnaz ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b Oncobiologics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; FRUCTOSE BISPHOSPHATASE; GLYCEROL; HYDROGEN PEROXIDE; OLEIC ACID; 2-NITRO-6-(4-(TRIFLUOROMETHOXY)BENZYLOXY)-6,7-DIHYDRO-5H-IMIDAZO(2,1-B)(1,3)OXAZINE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CARBON; FATTY ACID; NITROIMIDAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL SURVIVAL; COLONY FORMING UNIT; CONTROLLED STUDY; GENE DELETION; GENE FUNCTION; GENE LOSS; GENE TARGETING; GENETIC ANALYSIS; GLPX GENE; GLUCONEOGENESIS; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; MOUSE; MTB GENE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN FUNCTION; TUBERCULOSIS; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; MICROBIOLOGY; PHYSIOLOGICAL STRESS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CARBON; FATTY ACIDS; FRUCTOSE-BISPHOSPHATASE; GENE DELETION; GENES, BACTERIAL; GLUCONEOGENESIS; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MYCOBACTERIUM TUBERCULOSIS; NITROIMIDAZOLES; STRESS, PHYSIOLOGICAL; TUBERCULOSIS;

EID: 84946944593     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138436     Document Type: Article

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