Tether mutations that restore function and suppress pleiotropic phenotypes of the C. Elegans ISP-1(qm150) Rieske iron-sulfur protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 45, 2015, Pages E6148-E6157

  Jafari, Gholamali ^a   Wasko, Brian M ^a   Tonge, Ashley ^a   Schurman, Nathan ^a   Dong, Cindy ^a   Li, Zhongyu ^a   Peters, Rebecca ^a   Kayser, Ernst Bernhard ^b   Pitt, Jason N ^a   Morgan, Phil G ^b   Sedensky, Margaret M ^b   Crofts, Antony R ^c   Kaeberlein, Matt ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Aging; Complex III; Isp 1; Mitochondrial iron sulfur protein; Rip1

Indexed keywords

ASCORBIC ACID; CARBON DIOXIDE; GLUCOSE; IRON SULFUR PROTEIN; OXYGEN; RIP1 PROTEIN; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; ISP-1 PROTEIN, CAENORHABDITIS ELEGANS; NUCLEOPORIN; NUP42 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUINOL CYTOCHROME C REDUCTASE;

BODY MOVEMENT; CAENORHABDITIS ELEGANS; CONFERENCE PAPER; CONTROLLED STUDY; ELECTRON TRANSPORT; FLOW CYTOMETRY; GENE MUTATION; GENETIC SCREENING; GROWTH CURVE; HOMOZYGOTE; HYPEROXIA; HYPOXIA; LIFE EXTENSION; MUTAGENESIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONCENTRATION; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; UNFOLDED PROTEIN RESPONSE; ANIMAL; CHEMISTRY; CLUTCH SIZE; FLUORESCENCE MICROSCOPY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LONGEVITY; MOLECULAR MODEL; MOVEMENT (PHYSIOLOGY); MUTATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROTEIN ENGINEERING;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CLUTCH SIZE; ELECTRON TRANSPORT COMPLEX III; GENETIC PLEIOTROPY; GROWTH AND DEVELOPMENT; LONGEVITY; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOVEMENT; MUTAGENESIS; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; PHENOTYPE; PROTEIN ENGINEERING; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 84946944534     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509416112     Document Type: Article

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