Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment

Oncotarget

Volumn 6, Issue 34, 2015, Pages 36292-36307

  Chakrabarti, Kristi R ^a   Whipple, Rebecca A ^a   Boggs, Amanda E ^a,b   Hessler, Lindsay K ^a   Bhandary, Lekhana ^a   Vitolo, Michele I ^a   Thompson, Keyata ^a   Martin, Stuart S ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

AMPK; Breast cancer metastasis; Microtentacles; Microtubule stability; Re attachment

Indexed keywords

6,7 DIHYDRO 4 HYDROXY 3 (2' HYDROXY 1,1' BIPHENYL 4 YL) 6 OXOTHIENO[2,3 B]PYRIDINE 5 CARBONITRILE; ALPHA TUBULIN; COFILIN; DORSOMORPHIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRONE DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; BREAST CANCER; CELL ADHESION; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROTENTACLE; MICROTUBULE; PROTEIN ACETYLATION; PROTEIN PHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; DRUG EFFECTS; ENZYMOLOGY; FEMALE; MCF-7 CELL LINE; METABOLISM; METASTASIS; PATHOLOGY; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; BREAST NEOPLASMS; CELL LINE, TUMOR; CYTOSKELETON; FEMALE; HUMANS; MCF-7 CELLS; MICROTUBULES; NEOPLASM METASTASIS; PYRAZOLES; PYRIMIDINES; PYRONES; THIOPHENES;

EID: 84946865850     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5345     Document Type: Article

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