Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway

Molecular Medicine Reports

Volumn 12, Issue 6, 2015, Pages 8041-8047

  Zhao, Wei ^a   Lu, Mingshu ^a   Zhang, Qiwen ^a  

^a the People's Hospital of Laiwu   (China)

Author keywords

Chloride intracellular channel 1; Gastric cancer; Invasion; P38 mitogen activated protein kinase signaling pathway; Reactive oxygen species

Indexed keywords

(2 CYCLOPENTYL 6,7 DICHLORO 2 METHYL 1 OXO 5 INDANYLOXY)ACETIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; CHLORIDE INTRACELLULAR CHANNEL 1; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CHLORIDE CHANNEL; CLIC1 PROTEIN, HUMAN; GLYCOLIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; EXTRACELLULAR SPACE; GASTRIC CANCER CELL LINE; METASTASIS; OXIDATIVE STRESS; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR CELL; TUMOR INVASION; WOUND HEALING; ANTAGONISTS AND INHIBITORS; CELL MOTION; DOWN REGULATION; DRUG EFFECTS; HUMAN; METABOLISM; PATHOLOGY; STOMACH TUMOR; TUMOR CELL LINE;

ACETYLCYSTEINE; CELL LINE, TUMOR; CELL MOVEMENT; CHLORIDE CHANNELS; DOWN-REGULATION; GLYCOLATES; HUMANS; IMIDAZOLES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 84946781826     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4459     Document Type: Article

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