Tissue factor and cancer metastasis: The role of intracellular and extracellular signaling pathways

Molecular Medicine

Volumn 10, Issue 1-6, 2004, Pages 6-11

  Versteeg, Henri H ^a   Spek, C Arnold ^a   Peppelenbosch, Maikel P ^a   Richel, Dick J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A; MEMBRANE PROTEIN; THROMBOPLASTIN;

ANGIOGENESIS; ANIMAL CELL; APOPTOSIS; BLOOD CLOTTING; CELL STIMULATION; CELL SURVIVAL; COLON CANCER; GENETIC TRANSCRIPTION; HUMAN; LIVER METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; TUMOR CELL;

ANIMALS; BLOOD COAGULATION; FACTOR VIIA; HUMANS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; THROMBOPLASTIN;

EID: 7444270318     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Fidler IJ. (1990) Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res. 50:6130-8.
2. Fidler IJ. (1990) Host and tumor factors in cancer metastasis. Eur. J. Clin. Invest. 20:481-6.
3. Bach RR. (1988) Initiation of coagulation by tissue factor. CRC Crit. Rev. Biochem. 23:339-68.
4. Bazan JF. (1990) Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. U.S.A. 87:6934-8.
5. Drake TA, Morrisey JH, Edgington TS. (1989) Selective cellular expression of tissue factor in human tissues: implications for disorders of hemostasis and thrombosis. Am. J. Pathol. 134:1087-97.
6. Wilcox JN, Smith KM, Schwartz SM. (1989) Localisation of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc. Natl. Acad. Sci. U.S.A. 86:2839-43.
7. Fleck RA, Rao LVM, Rapaport SI, Varki N. (1990) Localisation of human tissue factor antigen by immunostaining with monospecific, polyclanal anti-human tissue factor antibody. Thromb. Res. 57:765-81.
8. Montemurro P et al. (1985) Increased in vitro and in vivo generation of procoagulant activity (tissue factor) by mononuclear phagocytes after intralipid infusion in rabbits. Blood 65:1391-5.
9. Semeraro N, Triggiani R, Montemurro P, Cavallo LG, Colucci M. (1993) Enhanced endothelial tissue factor but normal thrombomodulin in endotoxin-treated rabbits. Thromb. Res. 71:479-86.
10. Broze GJ. (1995) Tissue factor pathway inhibitor and the revised theory of coagulation. Ann. Rev. Med. 46:103-12.
11. Rao LVM. (1992) Tissue factor as a tumor procoagulant. Cancer Metastasis Rev. 11:249-66.
12. Rickles FR, Hair GA, Zeff RA, Lee E, Bona RD. (1995) Tissue factor expression in human leukocytes and tumor cells. Thromb. Haemost. 74:391-5
13. Mueller BM, Reisfeld RA, Edgington TS, Ruf W. (1992) Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc. Natl. Acad. Sci. U.S.A. 89:11832-6.
14. Homada K et al. (1996) Expression of tissue factor correlates with grade of malignancy in human glioma. Cancer 77:1877-83.
15. Zhou JN, Ljungdahl S, Shoshan MC, Swedenbord J, Linder S. (1998) Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway. Mol. Carcinog. 21:234-43.
16. Shigemori C et al. (1998) Tissue factor, expression, and metastatic potential of colorectal cancer. Thromb. Haemost. 80:894-8.
17. Seto S et al. (2000) Tissue factor expression in human colorectal carcinoma: correlation with hepatic metastasis and impact on prognosis. Cancer 88:295-301.
18. Mueller BM, Ruf W. (1998) Requirement for binding of catalytically active factor VIIa in tissue factor dependent experimental metastasis. J. Clin. Invest. 101:1372-8.
19. Bugge TH et al. (1996) Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood: coagulation. Proc. Natl. Acad. Sci. U.S.A. 93:6258-61.
20. Carmeliet P et al. (1996) Role of tissue factor in embryonic blood vessel development. Nature 383:73-5.
21. Koomagi R, Volm M. (1998) Tissue-factor expression in human non-small-cell lung carcinoma measured by immunohistochemistry: correlation between tissue factor and angiogenesis. Int. J. Cancer 79:19-22.
22. Abdulkadir SA et al. (2000) Tissue factor expression and ongiogenesis in human prostate carcinoma. Hum Pathol. 31:443-7.
23. Takono S, Tsuboi K, Tomono Y, Mitsui Y, Nose T. (2000) Tissue factor, osteopontin, alphavbeto3 integrin expression in microvasculature of gliomas associated with vascular endothelial growth factor expression. Br. J. Cancer 82:1967-73.
24. Shoji M et al. (1998) Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. Am. J. Pathol. 152:399-411.
25. Zhang Y et al. (1994) Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice. J. Clin. Invest. 94:1320-7.
26. Hembraugh TA et al. (2003) Tissue factor/factor VIIa inhibitors block angiogenesis and tumor growth through a nanhemastatic mechanism. Cancer Res. 63:2997-3000.
27. Hados K et al. (1994) Crystal structure of the extracellular region of human tissue factor. Nature 370:662-6.
28. Muller YA, Ultsch MH, Kelley RF, de Vos AM. (1994) Structure of the extracellular domain of human tissue factor: location of the factor vIIa binding site. Biochemistry 33:10864-70.
29. Ott I, Fischer E, Miyagi Y, Mueller BM, Ruf W. (1998) A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280. J. Cell Biol. 140:1241-53.
30. Abe K et al. (1999) Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor. Proc. Natl. Acad. Sci. U.S.A. 96:8663-8.
31. Sørensen BB et al. (1999) Factor VIIa-induced p42/44 mitogen-activated protein kinase activation requires the proteolytic activity of Factor VIIa and is independent of the tissue factor cytoplasmic domain. J. Biol. Chem. 274:21349-54.
32. Camerer E, Huang W, Coughlin SR. (2000) Tissue factor and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc. Natl. Acad. Sci. U.S.A. 97:5255-60.
33. Petersen LC et al. (2000) Exclusion of known protease-activated receptors in factor VIIa-induced signal transduction. Thromb. Haemost. 83:571-6.
34. Riewald M, Ruf W. (2001) Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc. Natl. Acad. Sci. U.S.A. 98:7742-7.
35. Røttingen JA, Enden T, Camerer E, Iversen JG, Prydz H. (1995) Binding of human factor VIIa to tissue factor induces cytosolic Ca2+ signals in J82 cells, transfected Cos-1 cells, Madin Darby canine kidney cells and in human endothelial cells, induced to synthesize tissue factor. J. Biol. Chem. 270:4650-60.
36. Camerer E, Røttingen JA, Iversen JG, Prydz H. (1996) Coagulation factors VII and X induce Ca2+ oscillations in Madin-Dorby canine kidney cells only when proteolytically active. J. Biol. Chem. 271:29034-42.
37. Cunningham MA, Romas P, Hutchinson P, Holdsworth SR, Tipping PG. (1999) Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. Blood 94:3413-20.
38. Pendurthi UR, Alok D, Rao LV. (1997) Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: upregulation of poly(A) polymerase. Proc. Natl. Acad. Sci. U.S.A. 94:12598-603.
39. Masuda M, Nakamura S, Murakami T, Komiyamo Y, Takahashi H. (1996) Association of tissue factor with a g chain homodimer of the IgE receptor type I in cultured human monocytes. Eur. J. Immunol. 26:2529-32.
40. Poulsen LK et al. (1998) Signal transduction via the mitogen activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor. J. Biol. Chem. 273:6228-32.
41. Camerer E et al. (1999) Coagulation factors VIIa and Xa induce cell signaling leading to the upregulation of the egr-1 gene. J. Biol. Chem. 274:32225-33.
42. Melis E et al. (2001) Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development. Biochem. Biophys. Res. Commun. 286:580-6.
43. Versteeg HH et al. (2000) Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphotidylinositol 3-kinase, and Rac. J. Biol. Chem. 275:28750-6.
44. Versteeg HH et al. (2003) Regulation of the p21 Ras-MAP kinase pathway by facfor VIIa. J. Thromb. Haemost. 1:1012-8.
45. Herbert JM, de Frost D, Ollivier V, Melis E, Carmeliet P. (2001) Tissue factor is not involved in the mitogenic activity of factor VIIa. Biochem. Biophys. Res. Commun. 28:1074-7.
46. Blanc-Brude OP, Chambers RC, Leoni P, Dik WA, Laurent GJ. (2001) Factor Xa is a fibroblast mitogen via binding to effector-cell protease receptor-1 and autocrine release of PDGF. Am. J. Physiol. Cell Physiol. 281:C681-9.
47. Camerer E, Gjernes E, Wiiger M, Pringle S, Prydz H. (2000) Binding of factor VIIa to tissue factor on keratinocytes induces gene expression. J. Biol. Chem. 275:6580-5.
48. Pendurthi UR, Allen KE, Ezban M, Rao LV. (2000) Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction. J. Biol. Chem. 275:14632-41.
49. Versteeg HH et al. (2002) VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation. J. Biol. Chem. 277:27065-72.
50. Wang X, Gjernes E, Prydz H. (2002) Factor VIIa induces tissue factor-dependent up-regulation of interleukin-8 in a human keratinocyte line. J. Biol. Chem. 277:23620-6.
51. Sørensen BB, Rao LV, Tornehave D, Gammeltoft S, Petersen LC. (2003) Antiapoptotic effect of coagulation factor VIIa. Blood. 102:1708-15.
52. Versteeg HH, Spek CA, Richel DJ, Peppelenbosch MP. (2004) Coagulation factors VIIa and Xa inhibit apoptosis and anoikis. Oncogene 23:410-7.
53. Randolph GJ, Luther T, Albrecht A, Magdolen V, Muller WA. (1998) Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro. Blood 92:4167-77.