-
1
-
-
33751217466
-
Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment
-
Anderson ARA, Weaver AM, Cummings PT, Quaranta V. 2006. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell 127:905-915.
-
(2006)
Cell
, vol.127
, pp. 905-915
-
-
Anderson, A.R.A.1
Weaver, A.M.2
Cummings, P.T.3
Quaranta, V.4
-
2
-
-
33645070536
-
The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model
-
Bouez C, Reynaud C, Noblesse E, Thepot A, Gleyzal C, Kanitakis J, Perrier E, Damour O, Sommer P. 2006. The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model. Clin Cancer Res 12:1463-1469.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1463-1469
-
-
Bouez, C.1
Reynaud, C.2
Noblesse, E.3
Thepot, A.4
Gleyzal, C.5
Kanitakis, J.6
Perrier, E.7
Damour, O.8
Sommer, P.9
-
3
-
-
1542405875
-
Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma
-
Cairns RA, Hill RP. 2004. Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma. Cancer Res 64:2054-2061.
-
(2004)
Cancer Res
, vol.64
, pp. 2054-2061
-
-
Cairns, R.A.1
Hill, R.P.2
-
4
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. 2006. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440:1222-1226.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
Chi, J.T.7
Jeffrey, S.S.8
Giaccia, A.J.9
-
5
-
-
21644448430
-
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation
-
Fogelgren B, Polgar N, Szauter KM, Ujfaludi Z, Laczko R, Fong KS, Csiszar K. 2005. Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. J Biol Chem 280:24690-24697.
-
(2005)
J Biol Chem
, vol.280
, pp. 24690-24697
-
-
Fogelgren, B.1
Polgar, N.2
Szauter, K.M.3
Ujfaludi, Z.4
Laczko, R.5
Fong, K.S.6
Csiszar, K.7
-
6
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL. 1996. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16:4604-4613.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
7
-
-
33846211525
-
Hypoxia-regulated carbonic anhydrase IX expression in associated with poor survival in patients with invasive breast cancer
-
Hussain SA, Ganesan R, Reynolds G, Gross L, Stevens A, Pastorek J, Murray PG, Perunovic B, Anwar MS, Billingham L, James ND, Spooner D, Poole CJ, Rea DW, Palmer DH. 2007. Hypoxia-regulated carbonic anhydrase IX expression in associated with poor survival in patients with invasive breast cancer. Br J Cancer 96:104-109.
-
(2007)
Br J Cancer
, vol.96
, pp. 104-109
-
-
Hussain, S.A.1
Ganesan, R.2
Reynolds, G.3
Gross, L.4
Stevens, A.5
Pastorek, J.6
Murray, P.G.7
Perunovic, B.8
Anwar, M.S.9
Billingham, L.10
James, N.D.11
Spooner, D.12
Poole, C.J.13
Rea, D.W.14
Palmer, D.H.15
-
8
-
-
33846621475
-
Intracellular localization of the matrix enzyme lysyl oxidase in polarized epithelial cells
-
Jansen MK, Csiszar K. 2007. Intracellular localization of the matrix enzyme lysyl oxidase in polarized epithelial cells. Matrix Biol 26:136-139.
-
(2007)
Matrix Biol
, vol.26
, pp. 136-139
-
-
Jansen, M.K.1
Csiszar, K.2
-
9
-
-
0036682233
-
A molecular role for lysyl oxidase in breast cancer invasion
-
Kirschmann DA, Seftor EA, Fong SF, Nieva DR, Sullivan CM, Edwards EM, Sommer P, Csiszar K, Hendrix MJ. 2002. A molecular role for lysyl oxidase in breast cancer invasion. Cancer Res 62:4478-4483.
-
(2002)
Cancer Res
, vol.62
, pp. 4478-4483
-
-
Kirschmann, D.A.1
Seftor, E.A.2
Fong, S.F.3
Nieva, D.R.4
Sullivan, C.M.5
Edwards, E.M.6
Sommer, P.7
Csiszar, K.8
Hendrix, M.J.9
-
10
-
-
1642450672
-
Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis
-
Li PA, He Q, Cao T, Yong G, Szauter KM, Fong KS, Karlsson J, Keep MF, Csiszar K. 2004. Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis. Brain Res Mol Brain Res 120:115-122.
-
(2004)
Brain Res Mol Brain Res
, vol.120
, pp. 115-122
-
-
Li, P.A.1
He, Q.2
Cao, T.3
Yong, G.4
Szauter, K.M.5
Fong, K.S.6
Karlsson, J.7
Keep, M.F.8
Csiszar, K.9
-
11
-
-
33750437433
-
Lysyl oxidase: An oxidative enzyme and effector of cell function
-
Lucero H, Kagan HM. 2006. Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci 63:2304-2316.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 2304-2316
-
-
Lucero, H.1
Kagan, H.M.2
-
12
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. 1999. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
13
-
-
33847075075
-
The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer
-
Min C, Kirsch KH, Zhao Y, Jeay S, Palamakumbura AH, Trackman PC, Sonenshein GE. 2007. The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res 67:1105-1112.
-
(2007)
Cancer Res
, vol.67
, pp. 1105-1112
-
-
Min, C.1
Kirsch, K.H.2
Zhao, Y.3
Jeay, S.4
Palamakumbura, A.H.5
Trackman, P.C.6
Sonenshein, G.E.7
-
14
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver WM. 2005. Tensional homeostasis and the malignant phenotype. Cancer Cell 8:241-254.
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Lakins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
Reinhart-King, C.A.7
Margulies, S.S.8
Dembo, M.9
Boettiger, D.10
Hammer, D.A.11
Weaver, W.M.12
-
15
-
-
29244436384
-
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism
-
Payne SL, Fogelgren B, Hess AR, Seftor EA, Wiley EL, Fong SF, Csiszar K, Hendrix MJ, Kirschmann DA. 2005. Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Cancer Res 65:11429-11436.
-
(2005)
Cancer Res
, vol.65
, pp. 11429-11436
-
-
Payne, S.L.1
Fogelgren, B.2
Hess, A.R.3
Seftor, E.A.4
Wiley, E.L.5
Fong, S.F.6
Csiszar, K.7
Hendrix, M.J.8
Kirschmann, D.A.9
-
17
-
-
34547769774
-
Paradoxical roles for lysyl oxidases in cancer - a prospect
-
Payne SL, Hendrix MJC, Kirschmann DA. 2007. Paradoxical roles for lysyl oxidases in cancer - a prospect. J Cell Biochem 101:1338-1354.
-
(2007)
J Cell Biochem
, vol.101
, pp. 1338-1354
-
-
Payne, S.L.1
Hendrix, M.J.C.2
Kirschmann, D.A.3
-
18
-
-
34047250313
-
Lysyl oxidase interacts with hormone placental lactogen and synergistically promotes breast epithelial cell proliferation and migration
-
Polgar N, Fogelgren B, Shipley JM, Csiszar K. 2007. Lysyl oxidase interacts with hormone placental lactogen and synergistically promotes breast epithelial cell proliferation and migration. J Biol Chem 282:3262-3272.
-
(2007)
J Biol Chem
, vol.282
, pp. 3262-3272
-
-
Polgar, N.1
Fogelgren, B.2
Shipley, J.M.3
Csiszar, K.4
-
19
-
-
0037144460
-
Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway
-
Postovit LM, Adams MA, Lash GE, Heaton JP, Graham CH. 2002. Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway. J Biol Chem 277:35730-35737.
-
(2002)
J Biol Chem
, vol.277
, pp. 35730-35737
-
-
Postovit, L.M.1
Adams, M.A.2
Lash, G.E.3
Heaton, J.P.4
Graham, C.H.5
-
20
-
-
33745303045
-
Hypoxia signaling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. 2006. Hypoxia signaling in cancer and approaches to enforce tumour regression. Nature 441:437-443.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
21
-
-
33746088024
-
Metastasis suppressor proteins: Discovery, molecular mechanisms, and clinical application
-
Rinker-Schaeffer CW, O'Keefe JP, Welch DR, Theodorescu D. 2006. Metastasis suppressor proteins: Discovery, molecular mechanisms, and clinical application. Clin Cancer Res 12:3882-3889.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3882-3889
-
-
Rinker-Schaeffer, C.W.1
O'Keefe, J.P.2
Welch, D.R.3
Theodorescu, D.4
-
22
-
-
0034037286
-
Microenvironment-induced cancer metastasis
-
Rofstad EK. 2000. Microenvironment-induced cancer metastasis. Int J Radiat Biol 76:589-605.
-
(2000)
Int J Radiat Biol
, vol.76
, pp. 589-605
-
-
Rofstad, E.K.1
-
24
-
-
0033584438
-
Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p1259FAK) in cultured rat cardiac myocytes
-
Seko Y, Takahashi N, Sabe H, Tobe K, Kadowaki T, Nagai R. 1999. Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p1259FAK) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 262:290-296.
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 290-296
-
-
Seko, Y.1
Takahashi, N.2
Sabe, H.3
Tobe, K.4
Kadowaki, T.5
Nagai, R.6
-
25
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza GL. 2001. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 12:925-932.
-
(2001)
Curr Opin Cell Biol
, vol.12
, pp. 925-932
-
-
Semenza, G.L.1
-
26
-
-
0034464872
-
Hypoxia, HIF-1, and the pathophysiology of common human diseases
-
Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A. 2000. Hypoxia, HIF-1, and the pathophysiology of common human diseases. Adv Exp Med Biol 475:123-130.
-
(2000)
Adv Exp Med Biol
, vol.475
, pp. 123-130
-
-
Semenza, G.L.1
Agani, F.2
Feldser, D.3
Iyer, N.4
Kotch, L.5
Laughner, E.6
Yu, A.7
-
27
-
-
33745186178
-
The signaling and biological implications of FAK overexpression in cancer
-
Siesser PMF, Hanks SK. 2006. The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res 12:3233-3237.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3233-3237
-
-
Siesser, P.M.F.1
Hanks, S.K.2
-
28
-
-
33746851956
-
Tumor metastasis: Mechanistic insights and clinical challenges
-
Steeg PS. 2006. Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 12:895-903.
-
(2006)
Nat Med
, vol.12
, pp. 895-903
-
-
Steeg, P.S.1
-
29
-
-
0037279517
-
The hypoxic tumour microenvironment and metastatic progression
-
Subarsky P, Hill RP. 2003. The hypoxic tumour microenvironment and metastatic progression. Clin Exp Met 20:237-250.
-
(2003)
Clin Exp Met
, vol.20
, pp. 237-250
-
-
Subarsky, P.1
Hill, R.P.2
-
30
-
-
33746846469
-
Embryonic and tumorigenic pathways converge via Nodal signaling: Role in melanoma aggressiveness
-
Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. 2006. Embryonic and tumorigenic pathways converge via Nodal signaling: Role in melanoma aggressiveness. Nat Med 12:925-932.
-
(2006)
Nat Med
, vol.12
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Margaryan, N.V.3
Sam, A.4
Hess, A.R.5
Wheaton, W.W.6
Nickoloff, B.J.7
Topczewski, J.8
Hendrix, M.J.9
-
31
-
-
33645526302
-
Hypocatalasemic fibroblasts accumulate hydrogen peroxide and display age-associated pathologies
-
Wood CS, Koepke JI, Teng H, Boucher KK, Katz S, Chang P, Terlecky LJ, Papanayotou I, Walton PA, Terlecky SR. 2006. Hypocatalasemic fibroblasts accumulate hydrogen peroxide and display age-associated pathologies. Traffic 7:97-107.
-
(2006)
Traffic
, vol.7
, pp. 97-107
-
-
Wood, C.S.1
Koepke, J.I.2
Teng, H.3
Boucher, K.K.4
Katz, S.5
Chang, P.6
Terlecky, L.J.7
Papanayotou, I.8
Walton, P.A.9
Terlecky, S.R.10
|