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Volumn 6, Issue , 2015, Pages

Shared genetic aetiology of puberty timing between sexes and with health-related outcomes

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LIPID; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR BETA; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; G PROTEIN COUPLED RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HORMONE RECEPTOR; KAL1 PROTEIN, HUMAN; LEPTIN RECEPTOR; LEPTIN RECEPTOR, HUMAN; MCHR2 PROTEIN, HUMAN; NERVE PROTEIN; REPRESSOR PROTEIN; RETINOID X RECEPTOR ALPHA; RORB PROTEIN, HUMAN; SCLEROPROTEIN; SIM1 PROTEIN, HUMAN; TRIACYLGLYCEROL;

EID: 84946762645     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9842     Document Type: Article
Times cited : (94)

References (29)
  • 2
    • 84864828191 scopus 로고    scopus 로고
    • Timing of voice breaking in males associated with growth and weight gain across the life course
    • Ong, K. K. et al. Timing of voice breaking in males associated with growth and weight gain across the life course. J. Clin. Endocrinol. Metab. 97, 2844-2852 (2012).
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , pp. 2844-2852
    • Ong, K.K.1
  • 3
    • 0142248155 scopus 로고    scopus 로고
    • The timing of normal puberty and the age limits of sexual precocity: Variations around the world, secular trends, changes after migration
    • Parent, A. S. et al. The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, changes after migration. Endocr. Rev. 24, 668-693 (2003).
    • (2003) Endocr. Rev. , vol.24 , pp. 668-693
    • Parent, A.S.1
  • 4
    • 84947899470 scopus 로고    scopus 로고
    • Thirty new loci for age at menarche identified by a metaanalysis of genome-wide association studies
    • Elks, C. E. et al. Thirty new loci for age at menarche identified by a metaanalysis of genome-wide association studies. Nat. Genet. 42, 1077-1085 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 1077-1085
    • Elks, C.E.1
  • 5
    • 84908024873 scopus 로고    scopus 로고
    • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
    • Perry, J. R. et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature 514, 92-97 (2014).
    • (2014) Nature , vol.514 , pp. 92-97
    • Perry, J.R.1
  • 6
    • 66649105485 scopus 로고    scopus 로고
    • Genetic variation in LIN28B is associated with the timing of puberty
    • Ong, K. K. et al. Genetic variation in LIN28B is associated with the timing of puberty. Nat. Genet. 41, 729-733 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 729-733
    • Ong, K.K.1
  • 7
    • 84938675474 scopus 로고    scopus 로고
    • Rare coding variants and X-linked loci associated with age at menarche
    • Lunetta, K. L. et al. Rare coding variants and X-linked loci associated with age at menarche. Nat. Commun. 6, 7756 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 7756
    • Lunetta, K.L.1
  • 8
    • 84877714923 scopus 로고    scopus 로고
    • Approach to the patient with hypogonadotropic hypogonadism
    • Silveira, L. F., Latronico, A. C. Approach to the patient with hypogonadotropic hypogonadism. J. Clin. Endocrinol. Metab. 98, 1781-1788 (2013).
    • (2013) J. Clin. Endocrinol. Metab. , vol.98 , pp. 1781-1788
    • Silveira, L.F.1    Latronico, A.C.2
  • 9
    • 84879344554 scopus 로고    scopus 로고
    • Central precocious puberty caused by mutations in the imprinted gene MKRN3
    • Abreu, A. P. et al. Central precocious puberty caused by mutations in the imprinted gene MKRN3. N. Engl. J. Med. 368, 2467-2475 (2013).
    • (2013) N. Engl. J. Med. , vol.368 , pp. 2467-2475
    • Abreu, A.P.1
  • 10
    • 84881026639 scopus 로고    scopus 로고
    • A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci
    • Hinds, D. A. et al. A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat. Genet. 45, 907-911 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 907-911
    • Hinds, D.A.1
  • 11
    • 85000692305 scopus 로고    scopus 로고
    • An atlas of genetic correlations across human diseases and traits
    • (in the press)
    • Bulik-Sullivan, B. K. et al. An atlas of genetic correlations across human diseases and traits. Nat. Genet. (in the press) doi:10.1038/ng.3406 (2015).
    • (2015) Nat. Genet.
    • Bulik-Sullivan, B.K.1
  • 12
    • 80051767336 scopus 로고    scopus 로고
    • Efficient replication of over 180 genetic associations with selfreported medical data
    • Tung, J. Y. et al. Efficient replication of over 180 genetic associations with selfreported medical data. PLoS ONE 6, e23473 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e23473
    • Tung, J.Y.1
  • 13
    • 83255176681 scopus 로고    scopus 로고
    • The retinoid X receptors and their ligands
    • Dawson, M. I., Xia, Z. The retinoid X receptors and their ligands. Biochim. Biophys. Acta 1821, 21-56 (2012).
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 21-56
    • Dawson, M.I.1    Xia, Z.2
  • 14
    • 17844369402 scopus 로고    scopus 로고
    • 9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor
    • Chuang, K. H. et al. 9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor. Mol. Endocrinol. 19, 1200-1212 (2005).
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1200-1212
    • Chuang, K.H.1
  • 15
    • 41949117824 scopus 로고    scopus 로고
    • Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands
    • Macoritto, M. et al. Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands. J. Biol. Chem. 283, 4943-4956 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 4943-4956
    • Macoritto, M.1
  • 16
    • 80155172604 scopus 로고    scopus 로고
    • Genetic determinants of serum testosterone concentrations in men
    • Ohlsson, C. et al. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 7, e1002313 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002313
    • Ohlsson, C.1
  • 17
    • 84923171580 scopus 로고    scopus 로고
    • Genetic studies of body mass index yield new insights for obesity biology
    • Locke, A. E. et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 518, 197-206 (2015).
    • (2015) Nature , vol.518 , pp. 197-206
    • Locke, A.E.1
  • 18
    • 84951567261 scopus 로고    scopus 로고
    • Genetic regulation of puberty timing in humans
    • (in the press)
    • Day, F. R., Perry, J. R., Ong, K. K. Genetic regulation of puberty timing in humans. Neuroendocrinology. (in the press) doi: 10.1159/000431023 (2015).
    • (2015) Neuroendocrinology
    • Day, F.R.1    Perry, J.R.2    Ong, K.K.3
  • 19
    • 84879679155 scopus 로고    scopus 로고
    • Rare variants in single-minded 1 (SIM1) are associated with severe obesity
    • Ramachandrappa, S. et al. Rare variants in single-minded 1 (SIM1) are associated with severe obesity. J. Clin. Invest. 123, 3042-3050 (2013).
    • (2013) J. Clin. Invest. , vol.123 , pp. 3042-3050
    • Ramachandrappa, S.1
  • 20
    • 84934890942 scopus 로고    scopus 로고
    • Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: The UK Biobank study
    • Day, F., Elks, C. E., Murray, A. M., Ong, K. K., Perry, J. R. Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study. Sci. Rep. 5, 11208 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 11208
    • Day, F.1    Elks, C.E.2    Murray, A.M.3    Ong, K.K.4    Perry, J.R.5
  • 21
    • 84881181618 scopus 로고    scopus 로고
    • Pubertal timing and adult obesity and cardiometabolic risk in women and men: A systematic review and meta-analysis
    • Prentice, P., Viner, R. M. Pubertal timing and adult obesity and cardiometabolic risk in women and men: a systematic review and meta-analysis. Int. J. Obes. (Lond) 37, 1036-1043 (2013).
    • (2013) Int. J. Obes. (Lond) , vol.37 , pp. 1036-1043
    • Prentice, P.1    Viner, R.M.2
  • 22
    • 84891868620 scopus 로고    scopus 로고
    • Age at menarche and type 2 diabetes risk: The EPIC-InterAct study
    • Elks, C. E. et al. Age at menarche and type 2 diabetes risk: the EPIC-InterAct study. Diabetes Care 36, 3526-3534 (2013).
    • (2013) Diabetes Care , vol.36 , pp. 3526-3534
    • Elks, C.E.1
  • 23
    • 84862002169 scopus 로고    scopus 로고
    • Mendelian randomisation study of childhood BMI and early menarche
    • Mumby, H. S. et al. Mendelian randomisation study of childhood BMI and early menarche. J. Obes. 2011, 180729 (2011).
    • (2011) J. Obes. , vol.2011 , pp. 180729
    • Mumby, H.S.1
  • 24
    • 84904751759 scopus 로고    scopus 로고
    • Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
    • Cousminer, D. L. et al. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum. Mol. Genet. 23, 4452-4464 (2014).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 4452-4464
    • Cousminer, D.L.1
  • 25
    • 78650868469 scopus 로고    scopus 로고
    • Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life-course
    • Ong, K. K. et al. Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life-course. J. Clin. Endocrinol. Metab. 96, E125-E129 (2011).
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. E125-E129
    • Ong, K.K.1
  • 26
    • 84923946495 scopus 로고    scopus 로고
    • LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
    • Bulik-Sullivan, B. K. et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat. Genet. 47, 291-295 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 291-295
    • Bulik-Sullivan, B.K.1
  • 28
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han, B., Eskin, E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet. 88, 586-598 (2011).
    • (2011) Am. J. Hum. Genet. , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 29
    • 84942749132 scopus 로고    scopus 로고
    • Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome
    • Day, F. R. et al. Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Nat. Commun 6, 8464 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 8464
    • Day, F.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.