메뉴 건너뛰기




Volumn 98, Issue 5, 2013, Pages 1781-1788

Approach to the patient with hypogonadotropic hypogonadism

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GONADORELIN; LUTEINIZING HORMONE;

EID: 84877714923     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-3550     Document Type: Article
Times cited : (128)

References (43)
  • 1
    • 0031694570 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): Pathophysiological and genetic considerations
    • Seminara SB, Hayes FJ, Crowley WF Jr. Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev. 1998;19:521-539.
    • (1998) Endocr Rev , vol.19 , pp. 521-539
    • Seminara, S.B.1    Hayes, F.J.2    Crowley Jr., W.F.3
  • 3
    • 79959916267 scopus 로고    scopus 로고
    • Genetic basis and variable phenotypic expression of Kallmann syndrome: Towards a unifying theory
    • Mitchell AL, Dwyer A, Pitteloud N, Quinton R. Genetic basis and variable phenotypic expression of Kallmann syndrome: towards a unifying theory. Trends Endocrinol Metab. 2011;22:249-258.
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 249-258
    • Mitchell, A.L.1    Dwyer, A.2    Pitteloud, N.3    Quinton, R.4
  • 4
    • 0024470630 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome
    • Schwanzel-Fukuda M, Bick D, Pfaff DW. Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome. Brain Res Mol Brain Res. 1989;6:311-326.
    • (1989) Brain Res Mol Brain Res , vol.6 , pp. 311-326
    • Schwanzel-Fukuda, M.1    Bick, D.2    Pfaff, D.W.3
  • 5
    • 0000678016 scopus 로고
    • Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode
    • Wray S, Grant P, Gainer H. Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode. Proc Natl Acad Sci USA. 1989;86:8132-8136.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8132-8136
    • Wray, S.1    Grant, P.2    Gainer, H.3
  • 6
    • 0034828721 scopus 로고    scopus 로고
    • Idiopathic gonadotrophin deficiency: Genetic questions addressed through phenotypic characterization
    • Quinton R, Duke VM, Robertson A, et al. Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization. Clin Endocrinol (Oxf). 2001;55:163-174.
    • (2001) Clin Endocrinol (Oxf) , vol.55 , pp. 163-174
    • Quinton, R.1    Duke, V.M.2    Robertson, A.3
  • 7
    • 0015913282 scopus 로고
    • Impuberism and hypogonadism at induction into military service. Statistical study
    • Fromantin M, Gineste J, Didier A, Rouvier J. [Impuberism and hypogonadism at induction into military service. Statistical study]. Probl Actuels Endocrinol Nutr. 1973;16:179-199.
    • (1973) Probl Actuels Endocrinol Nutr , vol.16 , pp. 179-199
    • Fromantin, M.1    Gineste, J.2    Didier, A.3    Rouvier, J.4
  • 9
    • 84860114996 scopus 로고    scopus 로고
    • SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development
    • Young J, Metay C, Bouligand J, et al. SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development. Hum Reprod. 2012;27:1460-1465.
    • (2012) Hum Reprod , vol.27 , pp. 1460-1465
    • Young, J.1    Metay, C.2    Bouligand, J.3
  • 10
    • 77749255232 scopus 로고    scopus 로고
    • The recent genetics of hypogonadotrophic hypogonadism-novel insights and new questions
    • Semple RK, Topaloglu AK. The recent genetics of hypogonadotrophic hypogonadism-novel insights and new questions. Clin Endocrinol (Oxf). 2010;72:427-435.
    • (2010) Clin Endocrinol (Oxf) , vol.72 , pp. 427-435
    • Semple, R.K.1    Topaloglu, A.K.2
  • 11
    • 84857126496 scopus 로고    scopus 로고
    • Inactivating KISS1 mutation and hypogonadotropic hypogonadism
    • Topaloglu AK, Tello JA, Kotan LD, et al. Inactivating KISS1 mutation and hypogonadotropic hypogonadism. N Engl J Med. 2012; 366:629-635.
    • (2012) N Engl J Med , vol.366 , pp. 629-635
    • Topaloglu, A.K.1    Tello, J.A.2    Kotan, L.D.3
  • 12
    • 33846841151 scopus 로고    scopus 로고
    • Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism
    • Pitteloud N, Quinton R, Pearce S, et al. Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism. J Clin Invest. 2007;117:457-463.
    • (2007) J Clin Invest , vol.117 , pp. 457-463
    • Pitteloud, N.1    Quinton, R.2    Pearce, S.3
  • 13
    • 77957001039 scopus 로고    scopus 로고
    • Oligogenic basis of isolated gonadotropin-releasing hormone deficiency
    • Sykiotis GP, Plummer L, Hughes VA, et al. Oligogenic basis of isolated gonadotropin-releasing hormone deficiency. Proc Natl Acad Sci USA. 2010;107:15140-15144.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15140-15144
    • Sykiotis, G.P.1    Plummer, L.2    Hughes, V.A.3
  • 14
    • 0031059199 scopus 로고    scopus 로고
    • Adult-onset idiopathic hypogonadotropic hypogonadism-A treatable form of male infertility
    • Nachtigall LB, Boepple PA, Pralong FP, Crowley WF Jr. Adult-onset idiopathic hypogonadotropic hypogonadism-a treatable form of male infertility. N Engl J Med. 1997;336:410-415.
    • (1997) N Engl J Med , vol.336 , pp. 410-415
    • Nachtigall, L.B.1    Boepple, P.A.2    Pralong, F.P.3    Crowley Jr., W.F.4
  • 15
    • 77956580208 scopus 로고    scopus 로고
    • The long-term clinical follow-up and natural history of men with adultonset idiopathic hypogonadotropic hypogonadism
    • Dwyer AA, Hayes FJ, Plummer L, Pitteloud N, Crowley WF Jr. The long-term clinical follow-up and natural history of men with adultonset idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2010;95:4235-4243.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4235-4243
    • Dwyer, A.A.1    Hayes, F.J.2    Plummer, L.3    Pitteloud, N.4    Crowley Jr., W.F.5
  • 16
    • 77954414397 scopus 로고    scopus 로고
    • Identification of late-onset hypogonadism in middle-aged and elderly men
    • Wu FC, Tajar A, Beynon JM, et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med. 2010; 363:123-135.
    • (2010) N Engl J Med , vol.363 , pp. 123-135
    • Wu, F.C.1    Tajar, A.2    Beynon, J.M.3
  • 17
    • 84860751541 scopus 로고    scopus 로고
    • Characteristics of androgen deficiency in late-onset hypogonadism: Results from the European Male Aging Study (EMAS)
    • Tajar A, Huhtaniemi IT, O'Neill TW, et al. Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS). J Clin Endocrinol Metab. 2010; 97:1508-1516.
    • (2010) J Clin Endocrinol Metab , vol.97 , pp. 1508-1516
    • Tajar, A.1    Huhtaniemi, I.T.2    O'Neill, T.W.3
  • 18
    • 0022669377 scopus 로고
    • Hypogonadotropic disorders in men and women: Diagnosis and therapy with pulsatile gonadotropin-releasing hormone
    • Santoro N, Filicori M, Crowley WF Jr. Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone. Endocr Rev. 1986;7:11-23.
    • (1986) Endocr Rev , vol.7 , pp. 11-23
    • Santoro, N.1    Filicori, M.2    Crowley Jr., W.F.3
  • 19
    • 77954825540 scopus 로고    scopus 로고
    • Clinical practice. Functional hypothalamic amenorrhea
    • Gordon CM. Clinical practice. Functional hypothalamic amenorrhea. N Engl J Med. 2010;363:365-371.
    • (2010) N Engl J Med , vol.363 , pp. 365-371
    • Gordon, C.M.1
  • 20
    • 78751621790 scopus 로고    scopus 로고
    • Agenetic basis for functional hypothalamic amenorrhea
    • Caronia LM, Martin C, Welt CK, et al. Agenetic basis for functional hypothalamic amenorrhea. N Engl J Med. 2011;364:215-225.
    • (2011) N Engl J Med , vol.364 , pp. 215-225
    • Caronia, L.M.1    Martin, C.2    Welt, C.K.3
  • 21
    • 4344690525 scopus 로고    scopus 로고
    • Recombinant human leptin in women with hypothalamic amenorrhea
    • Welt CK, Chan JL, Bullen J, et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med. 2004;351: 987-997.
    • (2004) N Engl J Med , vol.351 , pp. 987-997
    • Welt, C.K.1    Chan, J.L.2    Bullen, J.3
  • 22
    • 79955620729 scopus 로고    scopus 로고
    • Leptin is an effective treatment for hypothalamic amenorrhea
    • Chou SH, Chamberland JP, Liu X, et al. Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci USA. 2011; 108:6585-6590.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6585-6590
    • Chou, S.H.1    Chamberland, J.P.2    Liu, X.3
  • 23
    • 0025909961 scopus 로고
    • 50-Year trends in the incidence of anorexia nervosa in Rochester, MN: A population-based study
    • Lucas AR, Beard CM, O'Fallon WM, Kurland LT. 50-Year trends in the incidence of anorexia nervosa in Rochester, MN: a population-based study. Am J Psychiatry. 1991;148:917-922.
    • (1991) Am J Psychiatry , vol.148 , pp. 917-922
    • Lucas, A.R.1    Beard, C.M.2    O'Fallon, W.M.3    Kurland, L.T.4
  • 24
    • 33751015476 scopus 로고    scopus 로고
    • Hospitalization of children and adolescents for eating disorders in the State of New York
    • Robergeau K, Joseph J, Silber TJ. Hospitalization of children and adolescents for eating disorders in the State of New York. J Adolesc Health. 2006;39:806-810.
    • (2006) J Adolesc Health , vol.39 , pp. 806-810
    • Robergeau, K.1    Joseph, J.2    Silber, T.J.3
  • 25
    • 15944368215 scopus 로고    scopus 로고
    • Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism
    • Semple RK, Achermann JC, Ellery J, et al. Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2005;90: 1849-1855.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1849-1855
    • Semple, R.K.1    Achermann, J.C.2    Ellery, J.3
  • 26
    • 77952641591 scopus 로고    scopus 로고
    • What is the optimal therapy for young males with hypogonadotropic hypogonadism
    • Han TS, Bouloux PM. What is the optimal therapy for young males with hypogonadotropic hypogonadism? Clin Endocrinol (Oxf). 2010;72:731-737.
    • (2010) Clin Endocrinol (Oxf) , vol.72 , pp. 731-737
    • Han, T.S.1    Bouloux, P.M.2
  • 27
    • 34548313698 scopus 로고    scopus 로고
    • Luteinizing hormone β mutation and hypogonadism in men and women
    • Lofrano-Porto A, Barra GB, Giacomini LA, et al. Luteinizing hormone β mutation and hypogonadism in men and women. N Engl J Med. 2007;357:897-904.
    • (2007) N Engl J Med , vol.357 , pp. 897-904
    • Lofrano-Porto, A.1    Barra, G.B.2    Giacomini, L.A.3
  • 28
    • 0030744037 scopus 로고    scopus 로고
    • Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone β-subunit gene
    • Layman LC, Lee EJ, Peak DB, et al. Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone β-subunit gene. N Engl J Med. 1997;337:607-611.
    • (1997) N Engl J Med , vol.337 , pp. 607-611
    • Layman, L.C.1    Lee, E.J.2    Peak, D.B.3
  • 29
    • 0036345561 scopus 로고    scopus 로고
    • FSH β gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia
    • Layman LC, Porto AL, Xie J, et al. FSH β gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia. J Clin Endocrinol Metab. 2002;87:3702-3707.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3702-3707
    • Layman, L.C.1    Porto, A.L.2    Xie, J.3
  • 30
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline
    • Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2010;95:2536-2559.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3
  • 31
    • 84855473428 scopus 로고    scopus 로고
    • Olfactory phenotypic spectrum in idiopathic hypogonadotropic hypogonadism: Pathophysiological and genetic implications
    • Lewkowitz-Shpuntoff HM, Hughes VA, Plummer L, et al. Olfactory phenotypic spectrum in idiopathic hypogonadotropic hypogonadism: pathophysiological and genetic implications. J Clin Endocrinol Metab. 2012;97:E136-E144.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Lewkowitz-Shpuntoff, H.M.1    Hughes, V.A.2    Plummer, L.3
  • 32
    • 84866992300 scopus 로고    scopus 로고
    • Addition of recombinant follicle-stimulating hormone to human chorionic gonadotropin treatment in adolescents and young adults with hypogonadotropic hypogonadism promotes normal testicular growth and may promote early spermatogenesis
    • Zacharin M, Sabin MA, Nair VV, Dagabdhao P. Addition of recombinant follicle-stimulating hormone to human chorionic gonadotropin treatment in adolescents and young adults with hypogonadotropic hypogonadism promotes normal testicular growth and may promote early spermatogenesis. Fertil Steril. 2012;98:836-842.
    • (2012) Fertil Steril , vol.98 , pp. 836-842
    • Zacharin, M.1    Sabin, M.A.2    Nair, V.V.3    Dagabdhao, P.4
  • 33
    • 0032960418 scopus 로고    scopus 로고
    • Induction of puberty with human chorionic gonadotropin and follicle-stimulating hormone in adolescent males with hypogonadotropic hypogonadism
    • Barrio R, de Luis D, Alonso M, Lamas A, Moreno JC. Induction of puberty with human chorionic gonadotropin and follicle-stimulating hormone in adolescent males with hypogonadotropic hypogonadism. Fertil Steril. 1999;71:244-248.
    • (1999) Fertil Steril , vol.71 , pp. 244-248
    • Barrio, R.1    De Luis, D.2    Alonso, M.3    Lamas, A.4    Moreno, J.C.5
  • 36
    • 62349105629 scopus 로고    scopus 로고
    • Role of gonadotropin-releasing hormone and human chorionic gonadotropin stimulation tests in differentiating patients with hypogonadotropic hypogonadism from those with constitutional delay of growth and puberty
    • Segal TY, Mehta A, Anazodo A, Hindmarsh PC, Dattani MT. Role of gonadotropin-releasing hormone and human chorionic gonadotropin stimulation tests in differentiating patients with hypogonadotropic hypogonadism from those with constitutional delay of growth and puberty. J Clin Endocrinol Metab. 2009;94:780-785.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 780-785
    • Segal, T.Y.1    Mehta, A.2    Anazodo, A.3    Hindmarsh, P.C.4    Dattani, M.T.5
  • 37
    • 78650048626 scopus 로고    scopus 로고
    • Baseline inhibin B and anti-Mullerian hormone measurements for diagnosis of hypogonadotropic hypogonadism (HH) in boys with delayed puberty
    • Coutant R, Biette-Demeneix E, Bouvattier C, et al. Baseline inhibin B and anti-Mullerian hormone measurements for diagnosis of hypogonadotropic hypogonadism (HH) in boys with delayed puberty. J Clin Endocrinol Metab. 2010;95:5225-5232.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 5225-5232
    • Coutant, R.1    Biette-Demeneix, E.2    Bouvattier, C.3
  • 38
    • 34548331152 scopus 로고    scopus 로고
    • Reversal of idiopathic hypogonadotropic hypogonadism
    • Raivio T, Falardeau J, Dwyer A, et al. Reversal of idiopathic hypogonadotropic hypogonadism. N Engl J Med. 2007;357:863-873.
    • (2007) N Engl J Med , vol.357 , pp. 863-873
    • Raivio, T.1    Falardeau, J.2    Dwyer, A.3
  • 39
    • 78650909514 scopus 로고    scopus 로고
    • Clinical review: Why is androgen replacement in males controversial?
    • Cunningham GR, Toma SM. Clinical review: why is androgen replacement in males controversial? J Clin Endocrinol Metab. 2011; 96:38-52.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 38-52
    • Cunningham, G.R.1    Toma, S.M.2
  • 40
    • 78650865745 scopus 로고    scopus 로고
    • Testosterone treatment of older men-why are controversies created
    • Swerdloff R, Wang C. Testosterone treatment of older men-why are controversies created? J Clin Endocrinol Metab. 2011;96:62-65.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 62-65
    • Swerdloff, R.1    Wang, C.2
  • 41
    • 76649143447 scopus 로고    scopus 로고
    • Screening of autosomal gene deletions in patients with hypogonadotropic hypogonadism using multiplex ligation-dependent probe amplification: Detection of a hemizygosis for the fibroblast growth factor receptor 1
    • Trarbach EB, Teles MG, Costa EM, et al. Screening of autosomal gene deletions in patients with hypogonadotropic hypogonadism using multiplex ligation-dependent probe amplification: detection of a hemizygosis for the fibroblast growth factor receptor 1. Clin Endocrinol (Oxf). 2010;72:371-376.
    • (2010) Clin Endocrinol (Oxf) , vol.72 , pp. 371-376
    • Trarbach, E.B.1    Teles, M.G.2    Costa, E.M.3
  • 42
    • 79952305260 scopus 로고    scopus 로고
    • Expanding the phenotype and genotype of female GnRH deficiency
    • Shaw ND, Seminara SB, Welt CK, et al. Expanding the phenotype and genotype of female GnRH deficiency. J Clin Endocrinol Metab. 2011;96:E566-E576.
    • (2011) J Clin Endocrinol Metab , vol.96
    • Shaw, N.D.1    Seminara, S.B.2    Welt, C.K.3
  • 43
    • 77954524010 scopus 로고    scopus 로고
    • Congenital idiopathic hypogonadotropic hypogonadism: Evidence of defects in the hypothalamus, pituitary, and testes
    • Sykiotis GP, Hoang XH, Avbelj M, et al. Congenital idiopathic hypogonadotropic hypogonadism: evidence of defects in the hypothalamus, pituitary, and testes. J Clin Endocrinol Metab. 2010; 95(6):3019-3027.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.6 , pp. 3019-3027
    • Sykiotis, G.P.1    Hoang, X.H.2    Avbelj, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.