mGluR3 Activation Recruits Cytoplasmic TWIK-1 Channels to Membrane that Enhances Ammonium Uptake in Hippocampal Astrocytes

Molecular Neurobiology

Volumn 53, Issue 9, 2016, Pages 6169-6182

  Wang, Wei ^a,b   Kiyoshi, Conrad M ^a   Du, Yixing ^a   Ma, Baofeng ^a   Alford, Catherine C ^a   Chen, Haijun ^c   Zhou, Min ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Ammonium; Astrocytes; Endosomal trafficking; Hippocampus; Metabotropic glutamate receptor 3; TWIK 1 channel

Indexed keywords

AMMONIA; AMMONIUM CHLORIDE; CYTOPLASM PROTEIN; GLUTAMIC ACID; GLUTAMINE; MEMBRANE PROTEIN; METABOTROPIC RECEPTOR 3; NEUROTRANSMITTER; POTASSIUM CHANNEL; RAB PROTEIN; TWIK 1 PROTEIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMMONIUM DERIVATIVE; KCNK1 PROTEIN, MOUSE; MESSENGER RNA; METABOTROPIC RECEPTOR; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

AMMONIUM UPTAKE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOPLASM; ENDOSOME; FEMALE; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; UPREGULATION; ANIMAL; C57BL MOUSE; CYTOLOGY; ENDOCYTOSIS; EXOCYTOSIS; GENETICS; KNOCKOUT MOUSE; METABOLISM;

AMMONIUM COMPOUNDS; ANIMALS; ASTROCYTES; CELL MEMBRANE; CYTOPLASM; ENDOCYTOSIS; ENDOSOMES; EXOCYTOSIS; HIPPOCAMPUS; MICE, INBRED C57BL; MICE, KNOCKOUT; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RAB GTP-BINDING PROTEINS; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84946761785     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9496-4     Document Type: Article

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