Freshly isolated hippocampal CA1 astrocytes comprise two populations differing in glutamate transporter and AMPA receptor expression

Journal of Neuroscience

Volumn 21, Issue 20, 2001, Pages 7901-7908

  Zhou, Min ^a   Kimelberg, Harold K ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

AMPA receptor; Fresh cell isolation; GFAP+ astrocytes; Glutamate transporter; Hippocampus; Patch clamp

Indexed keywords

AMPA RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE TRANSPORTER; ION CHANNEL; POTASSIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING AFFINITY; BRAIN REGION; CELL POPULATION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; GABAERGIC TRANSMISSION; HIPPOCAMPUS; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DENSITY; SYNAPTIC TRANSMISSION;

EID: 0035887859     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-20-07901.2001     Document Type: Article

References (43)

1. Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
2. Atypical neural messengers
3. Synaptic activation of glutamate transporters in hippocampal astrocytes
4. Glial contribution to glutamate uptake at Schaffer collateral-commissural synapses in the hippocampus
5. Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
6. Postnatal development of ionic currents in rat hippocampal astrocytes in situ
7. Excitatory amino acids directly depolarize rat brain astrocytes in primary culture
8. Developmental downregulation of ATP-sensitive potassium conductance in astrocytes in situ
9. Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry
10. Functional specialization and topographic segregation of hippocampal astrocytes
11. Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation
12. The concentration of synaptically released glutamate outside of the climbing fiber-Purkinje cell synaptic cleft
13. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
14. A/benzodiazepine receptors in acutely isolated hippocampal astrocytes
15. Glutamate transporter protein subtypes are expressed differentially during rat CNS development
16. Aspartate, glutamate and gamma-aminobutyric acid depolarize cultured astrocytes
17. Functional properties and substrate specificity of the cloned L-glutamate/L-aspartate transporter GLAST-1 from rat brain expressed in Xenopus oocytes
18. Extrasynaptic glutamate spillover in the hippocampus: Evidence and implications
19. The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain
20. +-dependent glutamate uptake
21. Neurogenesis and gliaogenesis in the postischemic brain
22. Monitoring glutamate release during LTP with glial transporter currents
23. Papain effects on rat hippocampal neurons in the slice preparation
24. Heterogeneity of astrocyte resting membrane potentials and intercellular coupling revealed by whole-cell and gramicidin-perforated patch recordings from cultured neocortical and hippocampal slice astrocytes
25. A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus
26. Anion currents and predicted glutamate flux through a neuronal glutamate transporter
27. Isolation of current components and partial reaction cycles in the glial glutamate transporter EAAT2
28. Molecular biology of mammalian plasma membrane amino acid transporters
29. Cloning and expression of a rat brain L-glutamate transporter
30. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals
31. Fibrous and protoplasmic astrocytes
32. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
33. Metabotropic glutamate receptors in freshly isolated astrocytes from rat hippocampus
34. Analysis of AMPA-R properties during postnatal development of mouse hippocampal astrocytes
35. Three-dimensional analysis of dendritic spines III. Glial sheath
36. News on glutamate receptors in glial cells
37. Properties of GABA and glutamate responses in identified glial cells of the mouse hippocampal slice
38. Neuropathology of the hippocampus and its susceptibility to neurotoxic insult
39. Three-dimensional relationships between hippocampal synapses and astrocytes
40. Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel
41. Ion fluxes associated with excitatory amino acid transport
42. o uptake capabilities
43. GFAP mRNA positive glia acutely isolated from rat hippocampus predominantly show complex current patterns