Role of CD47 in erythroid cells and in autoimmunity

Leukemia and Lymphoma

Volumn 45, Issue 7, 2004, Pages 1319-1327

  Oldenborg, Per Arne ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Autoimmune hemolytic anemia; Erythrocytes; Macrophages; Phagocytosis; SIRP

Indexed keywords

ANTIBODY; CD47 ANTIGEN; CELL MARKER; CELL PROTEIN; CELL RECEPTOR; CELL SURFACE PROTEIN; COMPLEMENT; ERYTHROCYTE BAND 3 PROTEIN; INTEGRIN; PROTEIN RH; SCLEROPROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; AUTOIMMUNE DISEASE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNITY; CELL DESTRUCTION; CELL MEMBRANE; CELL SURFACE; CELL TYPE; COMPLEX FORMATION; DENDRITIC CELL; ERYTHROID CELL; HOST CELL; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MACROPHAGE; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; SENSITIZATION;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANIMALS; ANION EXCHANGE PROTEIN 1, ERYTHROCYTE; ANTIGENS, CD; ANTIGENS, CD47; ANTIGENS, DIFFERENTIATION; AUTOANTIGENS; AUTOIMMUNITY; DENDRITIC CELLS; ERYTHROCYTE AGING; ERYTHROCYTE MEMBRANE; HUMANS; MACROMOLECULAR SUBSTANCES; MACROPHAGE ACTIVATION; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; NEURAL CELL ADHESION MOLECULE L1; PHAGOCYTOSIS; RECEPTORS, IMMUNOLOGIC; RH-HR BLOOD-GROUP SYSTEM; SELF TOLERANCE; SIGNAL TRANSDUCTION;

EID: 2542534472     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/1042819042000201989     Document Type: Review

References (52)

1. Lindberg, F.P., Gresham, H.D., Schwarz, E. and Brown, E.J. (1993) "Molecular cloning of Integrin-Associated Protein: an immunoglobulin family member with multiple membrane spanning domains implicated in alpha-v, beta-3-dependent ligand binding", J. Cell Biol., 123, 485-496.
2. Brown, E.J., Hooper, L., Ho, T. and Gresham, H.D. (1990) "Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins", J. Cell Biol., 111, 2785-2794.
3. 3", J. Biol. Chem., 272, 14740-14746.
4. Wang, X.Q. and Frazier, W.A. (1998) "The thrombospondin receptor CD47 modulates and associates with α2β1 integrin in vascular smooth muscle cells", Mol. Biol. Cell, 9, 865-874.
5. Lindberg, F.P., Lublin, D.M., Telen, M.J., Veile, R.A., Miller, Y.E., Donis-Keller, H., et al. (1994) "Rh-related antigen CD47 is the signal-transducer integrin associated protein", J. Biol. Chem., 269, 1567-1570.
6. Campbell, I.G., Freemont, P.S., Foulkes, W. and Trowsdale, J. (1992) "An ovarian tumor marker with homology to vaccinia virus contains an IgV-like region and multiple transmembrane domains", Cancer Res., 52, 5416-5420.
7. Poels, L.G., Peters, D., van Megen, Y., Vooijs, G.P., Verheyen, R.N., Willemen, A., et al. (1986) "Monoclonal antibody against human ovarian tumor-associated antigens", J. Natl. Cancer Inst., 76, 781-791.
8. Parkos, C.A., Colgan, S.P., Liang, T.W., Nusrat, A., Bacarra, A.E., Carnes, D.K., et al. (1996) "CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia", J. Cell Biol., 132, 437-450.
9. Lindberg, F.P., Bullard, D.C., Caver, T.E., Gresham, H.D., Beaudet, A.L. and Brown, E.J. (1996) "Decreased resistance to bacterial infection and granulocyte defects in IAP-deficient mice", Science, 274, 795-798.
10. 3 function through integrin-associated protein", J. Biol. Chem., 135, 533-544.
11. Manna, P.P. and Frazier, W.A. (2003) "The mechanism of CD47-dependent killing of T cells: heterotrimeric Gi-dependent inhibition of protein kinase A", J. Immunol., 170, 3544-3553.
12. Pettersen, R.D., Hestdal, K., Olafsen, K., Lie, S.O. and Lindberg, F.P. (1999) "CD47 signals T cell death", J. Immunol., 162, 7031-7040.
13. Mateo, V., Lagneaux, L., Bron, D., Biron, G., Armant, M., Delespesse, G., et al. (1999) "CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia", Nat. Med., 5, 1277-1284.
14. vβ3 and integrin- associated protein", J. Cell Biol., 130, 745-754.
15. i", J. Biol. Chem., 274, 8554-8560.
16. Rebres, R.A., Vaz, L.E., Green, J.M. and Brown, E.J. (2001) "Normal ligand binding and signaling by CD47 (Integrin-associated protein) requires a long range disulfide bond between the extracellular and membrane-spanning domains", J. Biol. Chem., 276, 34607-34616.
17. null human erythrocytes", Biochem. J., 251, 499-505.
18. Cartron, J.P. (1999) "Rh blood group system and molecular basis of Rh-deficiency", Balliéres Best Pract. Res. Clin. Haematol., 12, 655-689.
19. Rybicki, A.C., Schwartz, R.S., Hustedt, E.J. and Cobb, C.E. (1996) "Increased rotational mobility and extractability of band 3 from protein 4.2-deficient erythrocyte membranes: evidence of a role for protein 4.2 in strengthening the band 3-cytoskeleton linkage", Blood, 88, 2745-2753.
20. Tanner, M.J. (2002) "Band 3 anion exchanger and its involvement in erythrocyte and kidney disorders", Curr. Opin. Hematol., 9, 133-139.
21. Bruce, L.J., Beckmann, R., Ribeiro, M.L., Peters, L.L., Chasis, J.A., Delaunay, J., et al. (2003) "A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane", Blood, 101, 4180-4188.
22. Booth, P.B., Serjeantson, S., Woodfield, D.G. and Amato, D. (1977) "Selective depression of blood group antigens associated with hereditary ovalocytosis among melanesians", Vox Sang., 32, 99-110.
23. Bruce, L.J., Ghosh, S., King, M.J., Layton, D.M., Mawby, W.J., Stewart, G.W., et al. (2002) "Absence of CD47 in protein 4.2-deficient hereditary spherocytosis in man: an interaction between the Rh complex and the band 3 complex", Blood, 100, 1878-1885.
24. Dahl, K.N., Westhoff, C.M. and Discher, D.E. (2003) "Fractional attachment of CD47 (IAP) to the erythrocyte cytoskeleton and visual colocalization with Rh protein complexes", Blood, 101, 1194-1199.
25. Mouro-Chanteloup, I., Johansen, M., Brown, E.J. and Cartron, J.P.C.Y. (2000) "Normal red cell membrane expression of Rh and RhAG polypeptides in CD47-deficient mice [abstract]", Vox Sang., 78, P030.
26. Mouro-Chanteloup, I., Delaunay, J., Gane, P., Nicolas, V., Johansen, M., Brown, E.J., et al. (2003) "Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47", Blood, 101, 338-344.
27. Brittain, J.E., Mlinar, K.J., Anderson, C.S., Orringer, E.P. and Parise, L.V. (2001) "Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction.", J. Clin. Invest., 107, 1555-1562.
28. Jiang, P., Lagenaur, C.F. and Narayanan, V. (1999) "Integrin-associated protein is a ligand for the P84 neural adhesion molecule", J. Biol. Chem., 274, 559-562.
29. Mi, Z.P., Jiang, P., Weng, W.L., Lindberg, F.P., Narayanan, V. and Lagenaur, C.F. (2000) "Expression of a synapse-associated membrane protein, P84/SHPS-1, and its ligand, IAP/CD47, in mouse retina", J. Comp. Neurol., 416, 335-344.
30. Seiffert, M., Cant, C., Chen, Z., Rappold, I., Brugger, W., Kanz, L., et al. (1999) "Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterrecteptor CD47", Blood, 94, 3633-3643.
31. Lienard, H., Bruhns, P., Malbec, O., Fridman, W.H. and Daëron, M. (1999) "Signal regulatory proteins negatively regulate immunoreceptor-dependent cell activation", J. Biol. Chem., 274, 32493-32499.
32. Oldenborg, P.-A., Zheleznyak, A., Fang, Y.-F., Lagenaur, C.F., Gresham, H.D. and Lindberg, F.P. (2000) "Role of CD47 as a marker of self on red blood cells", Science, 288, 2051-2054.
33. Oldenborg, P.-A., Gresham, H.D. and Lindberg, F.P. (2001) "CD47-SIRPα regulates Fcγ and complement receptor-mediated phagocytosis", J. Exp. Med., 193, 855-862.
34. Lanier, L.L. (1998) "NK cell receptors", Annu. Rev. Immunol., 16, 359-393.
35. Ljunggren, H.G. and Kärre, K. (1985) "Host resistance directed against H-2-deficient lymphoma variants. Analysis of the mechanism", J. Exp. Med., 162, 1745-1759.
36. Ravaetch, J.V. and Lanier, L.L. (2000) "Immune inhibitory receptors.", Science, 290, 84-89.
37. Kharitonenkov, A., Chen, Z., Sures, I., Wang, H., Schilling, J. and Ullrich, A. (1997) "A family of proteins that inhibit signalling through tyrosine kinase receptors", Nature, 386, 181-186.
38. Veillette, A., Thibaudeau, E. and Latour, S. (1998) "High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages", J. Biol. Chem., 273, 22719-22728.
39. Tonks, N.K. and Neel, B.G. (1996) "From form to function: Signaling by protein tyrosine phosphatases", Cell, 87, 365-368.
40. Liu, Y., Bühring, H.-J., Zen, K., Burst, S.L., Schnell, F.J., Williams, I.R., et al. (2002) "Signal regulatory protein (SIRPα), a cellular ligand for CD47, regulates neutrophil transmigration", J. Biol. Chem., 277, 10028-10036.
41. Blazar, B.R., Lindberg, F.P., Ingulli, E., Panoskaltsis-Mortari, A., Oldenborg, P.-A., Iizuka, K., et al. (2001) "CD47 (Integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent clearance of donor lymphohematopoietic cells", J. Exp. Med., 194, 541-549.
42. Engelfriet, C.P., Overbeeke, M.A.M. and Krvon dem Borne, A.E.G. (1992) "Autoimmune hemolytic anemia", Semin. Hematol., 29, 3-12.
43. Logue, G.L. and Kurlander, R.J. (1978) "Immunologic mechanisms of hemolysis in autoimmune hemolytic anemia", Pathobiol. Annu., 8, 61-83.
44. Ehlenberger, A.G. and Nussenzweig, V. (1977) "The role of membrane receptors for C3b and C3d in phagocytosis", J. Exp. Med., 145, 357-371.
45. Gigli, I. and Nelson, R.A. (1968) "Complement dependent immune phagocytosis", Exp. Cell Res., 51, 45-67.
46. Brown, E.J. (1991) "Complement receptors and phagocytosis", Curr. Opin. Immunol., 3, 76-82.
47. Baxter, A.G. and Mandel, T.E. (1991) "Hemolytic anemia in non-obese diabetic mice", Eur. J. Immunol., 21, 2051-2055.
48. Oldenborg, P.-A., Gresham, H.D., Chen, Y., Izui, S. and Lindberg, F.P. (2002) "Lethal autoimmune hemolytic anemia in CD47-deficient NOD mice", Blood, 99, 3500-3504.
49. Weiner, W. and Vos, G.H. (1963) "Serology of aquired hemolytic anemias", Blood, 22, 606-613.
50. Bratosin, D., Mazurier, J., Tissier, J.P., Estaquier, J., Huart, J.J., Ameisen, J.C., et al. (1998) "Cellular and molecular mechanisms of senescent erythrocyte phagocytosis by macrophages. A review", Biochimie, 80, 173-195.
51. Fossati-Jimack, L., Azeredo da Silvera, S., Moll, T., Kina, T., Kuypers, F.A., Oldenborg, P.-A., et al. (2002) "Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses", J. Autoimmun., 18, 17-25.
52. Anniss, A.M. and Sparrow, R.L. (2002) "Expression of CD47 (integrin-associated protein) decreases on red blood cells during storage", Transfus. Apheresis Sei., 27, 233-238.