-
1
-
-
67650874081
-
Cancer statistics
-
2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009;59:225-49.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
Zhang L, Conejo-Garcia JR, Katsaros D, Gimotty PA, Massobrio M, Regnani G, et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med 2003;348:203-13.
-
(2003)
N Engl J Med
, vol.348
, pp. 203-213
-
-
Zhang, L.1
Conejo-Garcia, J.R.2
Katsaros, D.3
Gimotty, P.A.4
Massobrio, M.5
Regnani, G.6
-
3
-
-
84856021596
-
Prognostic significance of tumor-infiltrating T cells in ovarian cancer: Ameta-analysis
-
Hwang WT, Adams SF, Tahirovic E, Hagemann IS, Coukos G. Prognostic significance of tumor-infiltrating T cells in ovarian cancer: Ameta-analysis. Gynecol Oncol 2012;124:192-8.
-
(2012)
Gynecol Oncol
, vol.124
, pp. 192-198
-
-
Hwang, W.T.1
Adams, S.F.2
Tahirovic, E.3
Hagemann, I.S.4
Coukos, G.5
-
4
-
-
61349151645
-
Intraepithelial T cells and prognosis in ovarian carcinoma: Novel associations with stage, tumor type, and BRCA1 loss
-
Clarke B, Tinker AV, Lee CH, Subramanian S, van De Rijn M, Turbin D, et al. Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type, and BRCA1 loss. Mod Pathol 2009;22: 393-402.
-
(2009)
Mod Pathol
, vol.22
, pp. 393-402
-
-
Clarke, B.1
Tinker, A.V.2
Lee, C.H.3
Subramanian, S.4
Van De Rijn, M.5
Turbin, D.6
-
5
-
-
84905753981
-
Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer
-
2014 ASCO Annual Meeting; 2014; Chicago, Illinois, USA
-
Hamanishi J, Mandai M, Ikeda T, Minami M, Kawaguchi A, Matsumura N, et al. Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer. 2014 ASCO Annual Meeting; 2014; Chicago, Illinois, USA: J Clin Oncol; 2014.
-
(2014)
J Clin Oncol
-
-
Hamanishi, J.1
Mandai, M.2
Ikeda, T.3
Minami, M.4
Kawaguchi, A.5
Matsumura, N.6
-
6
-
-
84879104519
-
Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors
-
Duraiswamy J, Kaluza KM, Freeman GJ, Coukos G. Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. Cancer Res 2013;73:3591-603.
-
(2013)
Cancer Res
, vol.73
, pp. 3591-3603
-
-
Duraiswamy, J.1
Kaluza, K.M.2
Freeman, G.J.3
Coukos, G.4
-
7
-
-
84880664259
-
Indoleamine 2, 3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
-
Holmgaard RB, Zamarin D, Munn DH, Wolchok JD, Allison JP. Indoleamine 2, 3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4. J Exp Med 2013;210:1389-402.
-
(2013)
J Exp Med
, vol.210
, pp. 1389-1402
-
-
Holmgaard, R.B.1
Zamarin, D.2
Munn, D.H.3
Wolchok, J.D.4
Allison, J.P.5
-
8
-
-
84860382842
-
CD73- deficientmice are resistant to carcinogenesis
-
Stagg J, Beavis PA, Divisekera U, Liu MC, Moller A, Darcy PK, et al. CD73- deficientmice are resistant to carcinogenesis. Cancer Res 2012;72:2190-6.
-
(2012)
Cancer Res
, vol.72
, pp. 2190-2196
-
-
Stagg, J.1
Beavis, P.A.2
Divisekera, U.3
Liu, M.C.4
Moller, A.5
Darcy, P.K.6
-
9
-
-
79954576658
-
CD73-deficientmice have increased antitumor immunity and are resistant to experimental metastasis
-
Stagg J, Divisekera U, Duret H, Sparwasser T, Teng MW, Darcy PK, et al. CD73-deficientmice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res 2011;71:2892-900.
-
(2011)
Cancer Res
, vol.71
, pp. 2892-2900
-
-
Stagg, J.1
Divisekera, U.2
Duret, H.3
Sparwasser, T.4
Teng, M.W.5
Darcy, P.K.6
-
10
-
-
75949112218
-
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
-
Stagg J, Divisekera U, McLaughlin N, Sharkey J, Pommey S, Denoyer D, et al. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc Natl Acad Sci U S A 2010;107:1547-52.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1547-1552
-
-
Stagg, J.1
Divisekera, U.2
McLaughlin, N.3
Sharkey, J.4
Pommey, S.5
Denoyer, D.6
-
11
-
-
79957921286
-
CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice
-
Wang L, Fan J, Thompson LF, Zhang Y, Shin T, Curiel TJ, et al. CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice. J Clin Invest 2011;121:2371-82.
-
(2011)
J Clin Invest
, vol.121
, pp. 2371-2382
-
-
Wang, L.1
Fan, J.2
Thompson, L.F.3
Zhang, Y.4
Shin, T.5
Curiel, T.J.6
-
12
-
-
84891824680
-
Anti-CD73 therapy impairs tumor angiogenesis
-
Allard B, Turcotte M, Spring K, Pommey S, Royal I, Stagg J. Anti-CD73 therapy impairs tumor angiogenesis. Int J Cancer 2014;134:1466-73.
-
(2014)
Int J Cancer
, vol.134
, pp. 1466-1473
-
-
Allard, B.1
Turcotte, M.2
Spring, K.3
Pommey, S.4
Royal, I.5
Stagg, J.6
-
13
-
-
84904433795
-
Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer
-
Allard B, Turcotte M, Stagg J. Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer. Expert Opin Ther Targets 2014;18:863-81.
-
(2014)
Expert Opin Ther Targets
, vol.18
, pp. 863-881
-
-
Allard, B.1
Turcotte, M.2
Stagg, J.3
-
14
-
-
84883422236
-
Blockade of A2A receptors potently suppresses the metastasis of CD73 tumors
-
Beavis PA, Divisekera U, Paget C, Chow MT, John LB, Devaud C, et al. Blockade of A2A receptors potently suppresses the metastasis of CD73 tumors. Proc Natl Acad Sci U S A 2013;110:14711-6.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 14711-14716
-
-
Beavis, P.A.1
Divisekera, U.2
Paget, C.3
Chow, M.T.4
John, L.B.5
Devaud, C.6
-
15
-
-
84879705407
-
CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
-
Loi S, Pommey S, Haibe-Kains B, Beavis PA, Darcy PK, Smyth MJ, et al. CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer. Proc Natl Acad Sci U S A 2013;110:11091-6.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 11091-11096
-
-
Loi, S.1
Pommey, S.2
Haibe-Kains, B.3
Beavis, P.A.4
Darcy, P.K.5
Smyth, M.J.6
-
16
-
-
84892958157
-
Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion
-
Hausler SF, Del Barrio IM, Diessner J, Stein RG, Strohschein J, Honig A, et al. Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion. Am J Transl Res 2014;6:129-39.
-
(2014)
Am J Transl Res
, vol.6
, pp. 129-139
-
-
Hausler, S.F.1
Del, B.I.M.2
Diessner, J.3
Stein, R.G.4
Strohschein, J.5
Honig, A.6
-
17
-
-
84875590401
-
Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma
-
Lu XX, Chen YT, Feng B, Mao XB, Yu B, Chu XY. Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma. World J Gastroenterol 2013;19:1912-8.
-
(2013)
World J Gastroenterol
, vol.19
, pp. 1912-1918
-
-
Lu, X.X.1
Chen, Y.T.2
Feng, B.3
Mao, X.B.4
Yu, B.5
Chu, X.Y.6
-
18
-
-
84896702712
-
NT5E and FcGBP as key regulators of TGF- 1-induced epithelial-mesenchymal transition (EMT) are associated with tumor progression and survival of patients with gallbladder cancer
-
Xiong L, Wen Y, Miao X, Yang Z. NT5E and FcGBP as key regulators of TGF- 1-induced epithelial-mesenchymal transition (EMT) are associated with tumor progression and survival of patients with gallbladder cancer. Cell Tissue Res 2014;355:365-74.
-
(2014)
Cell Tissue Res
, vol.355
, pp. 365-374
-
-
Xiong, L.1
Wen, Y.2
Miao, X.3
Yang, Z.4
-
19
-
-
84863722239
-
High expression of CD73 as a poor prognostic biomarker in human colorectal cancer
-
Wu XR, He XS, Chen YF, Yuan RX, Zeng Y, Lian L, et al. High expression of CD73 as a poor prognostic biomarker in human colorectal cancer. J Surg Oncol 2012;106:130-7.
-
(2012)
J Surg Oncol
, vol.106
, pp. 130-137
-
-
Wu, X.R.1
He, X.S.2
Chen, Y.F.3
Yuan, R.X.4
Zeng, Y.5
Lian, L.6
-
20
-
-
84867173653
-
Overexpression of CD73 in epithelial ovarian carcinoma is associated with better prognosis, lower stage, better differentiation and lower regulatory T cell infiltration
-
Oh HK, Sin JI, Choi J, Park SH, Lee TS, Choi YS. Overexpression of CD73 in epithelial ovarian carcinoma is associated with better prognosis, lower stage, better differentiation and lower regulatory T cell infiltration. J Gynecol Oncol 2012;23:274-81.
-
(2012)
J Gynecol Oncol
, vol.23
, pp. 274-281
-
-
Oh, H.K.1
Sin, J.I.2
Choi, J.3
Park, S.H.4
Lee, T.S.5
Choi, Y.S.6
-
21
-
-
52649085237
-
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
-
Tothill RW, Tinker AV, George J, Brown R, Fox SB, Lade S, et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin Cancer Res 2008;14:5198-208.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5198-5208
-
-
Tothill, R.W.1
Tinker, A.V.2
George, J.3
Brown, R.4
Fox, S.B.5
Lade, S.6
-
22
-
-
84872703162
-
KLF6- SV1 drives breast cancer metastasis and is associated with poor survival
-
Hatami R, Sieuwerts AM, Izadmehr S, Yao Z, Qiao RF, Papa L, et al. KLF6- SV1 drives breast cancer metastasis and is associated with poor survival. Sci Transl Med 2013;5:169ra12.
-
(2013)
Sci Transl Med
, vol.5
, pp. 169ra12
-
-
Hatami, R.1
Sieuwerts, A.M.2
Izadmehr, S.3
Yao, Z.4
Qiao, R.F.5
Papa, L.6
-
23
-
-
84879407005
-
Curated Ovarian Data: Clinically annotated data for the ovarian cancer transcriptome
-
bat013
-
Ganzfried BF, Riester M, Haibe-Kains B, Risch T, Tyekucheva S, Jazic I, et al., curated Ovarian Data: clinically annotated data for the ovarian cancer transcriptome. Database 2013;2013:bat013.
-
(2013)
Database 2013
-
-
Ganzfried, B.F.1
Riester, M.2
Haibe-Kains, B.3
Risch, T.4
Tyekucheva, S.5
Jazic, I.6
-
24
-
-
80755144068
-
Survcomp: An R/Bioconductor package for performance assessment and comparison of survival models
-
Schroder MS, Culhane AC, Quackenbush J, Haibe-Kains B. "survcomp: An R/Bioconductor package for performance assessment and comparison of survival models." Bioinformatics 2011;27:3206-8.
-
(2011)
Bioinformatics
, vol.27
, pp. 3206-3208
-
-
Schroder, M.S.1
Culhane, A.C.2
Quackenbush, J.3
Haibe-Kains, B.4
-
25
-
-
79956076619
-
Definitions for response and progression in ovarian cancer clinical trials incorporating RECIST 1.1 and CA 125 agreed by the gynecological cancer intergroup (GCIG)
-
Rustin GJ, Vergote I, Eisenhauer E, Pujade-Lauraine E, Quinn M, Thigpen T, et al. Definitions for response and progression in ovarian cancer clinical trials incorporating RECIST 1.1 and CA 125 agreed by the Gynecological Cancer Intergroup (GCIG). Int J Gynecol Cancer 2011; 21:419-23.
-
(2011)
Int J Gynecol Cancer
, vol.21
, pp. 419-423
-
-
Rustin, G.J.1
Vergote, I.2
Eisenhauer, E.3
Pujade-Lauraine, E.4
Quinn, M.5
Thigpen, T.6
-
26
-
-
0037701271
-
Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types
-
Kelm JM, Timmins NE, Brown CJ, Fussenegger M, Nielsen LK. Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types. Biotechnol Bioeng 2003;83: 173-80.
-
(2003)
Biotechnol Bioeng
, vol.83
, pp. 173-180
-
-
Kelm, J.M.1
Timmins, N.E.2
Brown, C.J.3
Fussenegger, M.4
Nielsen, L.K.5
-
27
-
-
80054109170
-
Ectonucleotidases CD39 and CD73 onOvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity
-
Hausler SF, Montalban del Barrio I, Strohschein J, Anoop Chandran P, Engel JB, Honig A, et al. Ectonucleotidases CD39 and CD73 onOvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity. Cancer Immunol Immunother 2011;60:1405-18.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1405-1418
-
-
Hausler, S.F.1
Montalban Del Barrio, I.2
Strohschein, J.3
Anoop Chandran, P.4
Engel, J.B.5
Honig, A.6
-
28
-
-
77951702294
-
Differences in tumor type in low-stage versus high-stage ovarian carcinomas
-
Kobel M, Kalloger SE, Huntsman DG, Santos JL, Swenerton KD, Seidman JD, et al. Differences in tumor type in low-stage versus high-stage ovarian carcinomas. Int J Gynecol Pathol 2010;29:203-11.
-
(2010)
Int J Gynecol Pathol
, vol.29
, pp. 203-211
-
-
Kobel, M.1
Kalloger, S.E.2
Huntsman, D.G.3
Santos, J.L.4
Swenerton, K.D.5
Seidman, J.D.6
-
29
-
-
80053168788
-
Rethinking ovarian cancer: Recommendations for improving outcomes
-
Vaughan S, Coward JI, Bast RC Jr., Berchuck A, Berek JS, Brenton JD, et al. Rethinking ovarian cancer: recommendations for improving outcomes. Nat Rev Cancer 2011;11:719-25.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 719-725
-
-
Vaughan, S.1
Coward, J.I.2
Bast, R.C.3
Berchuck, A.4
Berek, J.S.5
Brenton, J.D.6
-
30
-
-
29444442811
-
Intraepithelial CD8 tumor-infiltrating lymphocytes and a high CD8/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
-
Sato E, Olson SH, Ahn J, Bundy B, Nishikawa H, Qian F, et al. Intraepithelial CD8 tumor-infiltrating lymphocytes and a high CD8/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci U S A 2005;102:18538-43.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18538-18543
-
-
Sato, E.1
Olson, S.H.2
Ahn, J.3
Bundy, B.4
Nishikawa, H.5
Qian, F.6
-
31
-
-
28544433483
-
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
-
Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, Muller-Holzner E, et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 2005;11:8326-31.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8326-8331
-
-
Wolf, D.1
Wolf, A.M.2
Rumpold, H.3
Fiegl, H.4
Zeimet, A.G.5
Muller-Holzner, E.6
-
32
-
-
34548798737
-
Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma
-
Kryczek I, Wei S, Zhu G, Myers L, Mottram P, Cheng P, et al. Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma. Cancer Res 2007;67:8900-5.
-
(2007)
Cancer Res
, vol.67
, pp. 8900-8905
-
-
Kryczek, I.1
Wei, S.2
Zhu, G.3
Myers, L.4
Mottram, P.5
Cheng, P.6
-
33
-
-
84875171283
-
PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction
-
Abiko K, Mandai M, Hamanishi J, Yoshioka Y, Matsumura N, Baba T, et al. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res 2013;19:1363-74.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1363-1374
-
-
Abiko, K.1
Mandai, M.2
Hamanishi, J.3
Yoshioka, Y.4
Matsumura, N.5
Baba, T.6
-
34
-
-
84886432843
-
Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs
-
Allard B, Pommey S, Smyth MJ, Stagg J. Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs. Clin Cancer Res 2013;19:5626-35.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 5626-5635
-
-
Allard, B.1
Pommey, S.2
Smyth, M.J.3
Stagg, J.4
-
35
-
-
77957564570
-
Extracellular adenosine triphosphate and adenosine in cancer
-
Stagg J, Smyth MJ. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 2010;29:5346-58.
-
(2010)
Oncogene
, vol.29
, pp. 5346-5358
-
-
Stagg, J.1
Smyth, M.J.2
-
36
-
-
77950231071
-
CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumorinduced immune suppression
-
Jin D, Fan J, Wang L, Thompson LF, Liu A, Daniel BJ, et al. CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumorinduced immune suppression. Cancer Res 2010;70:2245-55.
-
(2010)
Cancer Res
, vol.70
, pp. 2245-2255
-
-
Jin, D.1
Fan, J.2
Wang, L.3
Thompson, L.F.4
Liu, A.5
Daniel, B.J.6
-
37
-
-
0026029631
-
Expression of ecto-50 - nucleotidase (CD73) in normal mammary gland and in breast carcinoma
-
Kruger KH, Thompson LF, Kaufmann M, Moller P. Expression of ecto-50 - nucleotidase (CD73) in normal mammary gland and in breast carcinoma. Br J Cancer 1991;63:114-8.
-
(1991)
Br J Cancer
, vol.63
, pp. 114-118
-
-
Kruger, K.H.1
Thompson, L.F.2
Kaufmann, M.3
Moller, P.4
-
38
-
-
84905901473
-
The carcinoma-associated fibroblast expressing fibroblast activation protein and escape from immune surveillance
-
Fearon DT. The carcinoma-associated fibroblast expressing fibroblast activation protein and escape from immune surveillance. CancerImmunol Res 2014;2(3):187-93.
-
(2014)
CancerImmunol Res
, vol.2
, Issue.3
, pp. 187-193
-
-
Fearon, D.T.1
-
39
-
-
77955811853
-
Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells
-
Battula VL, Evans KW, Hollier BG, Shi Y, Marini FC, Ayyanan A, et al. Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells. Stem Cells 2010;28:1435-45.
-
(2010)
Stem Cells
, vol.28
, pp. 1435-1445
-
-
Battula, V.L.1
Evans, K.W.2
Hollier, B.G.3
Shi, Y.4
Marini, F.C.5
Ayyanan, A.6
-
40
-
-
84902178965
-
Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance
-
Davidowitz RA, Selfors LM, Iwanicki MP, Elias KM, Karst A, Piao H, et al. Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance. J Clin Invest 2014;124:2611-25.
-
(2014)
J Clin Invest
, vol.124
, pp. 2611-2625
-
-
Davidowitz, R.A.1
Selfors, L.M.2
Iwanicki, M.P.3
Elias, K.M.4
Karst, A.5
Piao, H.6
|