메뉴 건너뛰기




Volumn 7, Issue 1, 2015, Pages

Epigenetics and male reproduction: The consequences of paternal lifestyle on fertility, embryo development, and children lifetime health

Author keywords

DNA methylation; Epigenetics; Gametogenesis; Male infertility; Transgenerational effect

Indexed keywords

DNA METHYLTRANSFERASE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE H3; HISTONE H4; LONG UNTRANSLATED RNA; SMALL UNTRANSLATED RNA;

EID: 84946594785     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-015-0155-4     Document Type: Review
Times cited : (157)

References (175)
  • 1
    • 84871645744 scopus 로고    scopus 로고
    • National, regional, and global trends in infertility prevalence since 1990: A systematic analysis of 277 health surveys
    • Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med. 2012;9:e1001356.
    • (2012) Plos Med , vol.9
    • Mascarenhas, M.N.1    Flaxman, S.R.2    Boerma, T.3    Vanderpoel, S.4    Stevens, G.A.5
  • 2
    • 79952545010 scopus 로고    scopus 로고
    • Male infertility: Pathogenesis and clinical diagnosis
    • Krausz C. Male infertility: pathogenesis and clinical diagnosis. Best Pract Res Clin Endocrinol Metab. 2011;25:271-85.
    • (2011) Best Pract Res Clin Endocrinol Metab , vol.25 , pp. 271-285
    • Krausz, C.1
  • 4
    • 84890074366 scopus 로고    scopus 로고
    • A clinical appraisal of the genetic basis in unexplained male infertility
    • Esteves SC. A clinical appraisal of the genetic basis in unexplained male infertility. J Hum Reprod Sci. 2013;6:176-82.
    • (2013) J Hum Reprod Sci , vol.6 , pp. 176-182
    • Esteves, S.C.1
  • 5
    • 0031745195 scopus 로고    scopus 로고
    • A quarter of men with idiopathic oligo-azoospermia display chromosomal abnormalities and microdeletions of different types in interval 6 of Yq11
    • Stuppia L, Gatta V, Calabrese G, Franchi PG, Morizio E, Bombieri C, et al. A quarter of men with idiopathic oligo-azoospermia display chromosomal abnormalities and microdeletions of different types in interval 6 of Yq11. Hum Genet. 1998;102:566-70.
    • (1998) Hum Genet , vol.102 , pp. 566-570
    • Stuppia, L.1    Gatta, V.2    Calabrese, G.3    Franchi, P.G.4    Morizio, E.5    Bombieri, C.6
  • 6
    • 14044257269 scopus 로고    scopus 로고
    • Prevalence of chromosomal abnormalities in 2078 infertile couples referred for assisted reproductive techniques
    • Clementini E, Palka C, Iezzi I, Stuppia L, Guanciali-Franchi P, Tiboni GM. Prevalence of chromosomal abnormalities in 2078 infertile couples referred for assisted reproductive techniques. Hum Reprod. 2005;20:437-42.
    • (2005) Hum Reprod , vol.20 , pp. 437-442
    • Clementini, E.1    Palka, C.2    Iezzi, I.3    Stuppia, L.4    Guanciali-Franchi, P.5    Tiboni, G.M.6
  • 8
    • 77749240212 scopus 로고    scopus 로고
    • State of the art for genetic testing of infertile men
    • McLachlan RI, O’Bryan MK. State of the art for genetic testing of infertile men. J Clin Endocrinol Metab. 2010;95:1013-24.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1013-1024
    • McLachlan, R.I.1    O’Bryan, M.K.2
  • 10
    • 84876410606 scopus 로고    scopus 로고
    • The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility
    • Kovac JR, Pastuszak AW, Lamb DJ. The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility. Fertil Steril. 2013;99:998-1007.
    • (2013) Fertil Steril , vol.99 , pp. 998-1007
    • Kovac, J.R.1    Pastuszak, A.W.2    Lamb, D.J.3
  • 11
    • 0034527487 scopus 로고    scopus 로고
    • Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome
    • Moro E, Ferlin A, Yen PH, Franchi PG, Palka G, Foresta C. Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome. J Clin Endocrinol Metab. 2000;85:4069-73.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4069-4073
    • Moro, E.1    Ferlin, A.2    Yen, P.H.3    Franchi, P.G.4    Palka, G.5    Foresta, C.6
  • 12
    • 8744291701 scopus 로고    scopus 로고
    • Sequence family variant loss from the AZFc interval of the human Y chromosome, but not gene copy loss, is strongly associated with male infertility
    • Machev N, Saut N, Longepied G, Terriou P, Navarro A, Levy N, et al. Sequence family variant loss from the AZFc interval of the human Y chromosome, but not gene copy loss, is strongly associated with male infertility. J Med Genet. 2004;41:814-25.
    • (2004) J Med Genet , vol.41 , pp. 814-825
    • Machev, N.1    Saut, N.2    Longepied, G.3    Terriou, P.4    Navarro, A.5    Levy, N.6
  • 13
    • 12444336969 scopus 로고    scopus 로고
    • Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis
    • Hucklenbroich K, Gromoll J, Heinrich M, Hohoff C, Nieschlag E, Simoni M. Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis. Hum Reprod. 2005;20:191-97.
    • (2005) Hum Reprod , vol.20 , pp. 191-197
    • Hucklenbroich, K.1    Gromoll, J.2    Heinrich, M.3    Hohoff, C.4    Nieschlag, E.5    Simoni, M.6
  • 14
  • 18
    • 34147168217 scopus 로고    scopus 로고
    • Y-chromosome haplogroups and susceptibility to azoospermia factor c microdeletion in an Italian population
    • Arredi B, Ferlin A, Speltra E, Bedin C, Zuccarello D, Ganz F, et al. Y-chromosome haplogroups and susceptibility to azoospermia factor c microdeletion in an Italian population. J Med Genet. 2007;44:205-08.
    • (2007) J Med Genet , vol.44 , pp. 205-208
    • Arredi, B.1    Ferlin, A.2    Speltra, E.3    Bedin, C.4    Zuccarello, D.5    Ganz, F.6
  • 19
    • 0035185070 scopus 로고    scopus 로고
    • Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility
    • Rovio AT, Marchington DR, Donat S, Schuppe HC, Abel J, Fritsche E, et al. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Nat Genet. 2001;29:261-62.
    • (2001) Nat Genet , vol.29 , pp. 261-262
    • Rovio, A.T.1    Marchington, D.R.2    Donat, S.3    Schuppe, H.C.4    Abel, J.5    Fritsche, E.6
  • 20
    • 33644827312 scopus 로고    scopus 로고
    • The polymorphic polyglutamine repeat in the mitochondrial DNA polymerase gamma gene is not associated with oligozoospermia
    • Brusco A, Michielotto C, Gatta V, Foresta C, Matullo G, Zeviani M, et al. The polymorphic polyglutamine repeat in the mitochondrial DNA polymerase gamma gene is not associated with oligozoospermia. J Endocrinol Invest. 2006;29:1-4.
    • (2006) J Endocrinol Invest , vol.29 , pp. 1-4
    • Brusco, A.1    Michielotto, C.2    Gatta, V.3    Foresta, C.4    Matullo, G.5    Zeviani, M.6
  • 21
    • 84886383525 scopus 로고    scopus 로고
    • Mitochondrial DNA, polymerase gamma gene polymorphism is not associated with male infertility
    • Poongothai J. Mitochondrial DNA, polymerase gamma gene polymorphism is not associated with male infertility. J Assist Reprod Genet. 2013;30:1109-14.
    • (2013) J Assist Reprod Genet , vol.30 , pp. 1109-1114
    • Poongothai, J.1
  • 22
    • 84867290682 scopus 로고    scopus 로고
    • High resolution X chromosome-specific array-CGH detects new CNVs in infertile males
    • Krausz C, Giachini C, Lo Giacco D, Daguin F, Chianese C, Ars E, et al. High resolution X chromosome-specific array-CGH detects new CNVs in infertile males. PLoS ONE. 2012;7:e44887.
    • (2012) Plos ONE , vol.7
    • Krausz, C.1    Giachini, C.2    Lo Giacco, D.3    Daguin, F.4    Chianese, C.5    Ars, E.6
  • 23
    • 84902590088 scopus 로고    scopus 로고
    • X chromosome-linked CNVs in male infertility: Discovery of overall duplication load and recurrent, patient-specific gains with potential clinical relevance
    • Chianese C, Gunning AC, Giachini C, Daguin F, Balercia G, Ars E, et al. X chromosome-linked CNVs in male infertility: discovery of overall duplication load and recurrent, patient-specific gains with potential clinical relevance. PLoS ONE. 2014;9:e97746.
    • (2014) Plos ONE , vol.9
    • Chianese, C.1    Gunning, A.C.2    Giachini, C.3    Daguin, F.4    Balercia, G.5    Ars, E.6
  • 25
    • 77954701301 scopus 로고    scopus 로고
    • Why Your DNA Isn’t Your Destiny
    • Cloud J. Why Your DNA Isn’t Your Destiny, Time Magazine. 2010.
    • (2010) Time Magazine
    • Cloud, J.1
  • 30
    • 84855281409 scopus 로고    scopus 로고
    • Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
    • Ziller MJ, Muller F, Liao J, Zhang Y, Gu H, Bock C, et al. Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. PLoS Genet. 2011;7:e1002389.
    • (2011) Plos Genet , vol.7
    • Ziller, M.J.1    Muller, F.2    Liao, J.3    Zhang, Y.4    Gu, H.5    Bock, C.6
  • 31
    • 84857467013 scopus 로고    scopus 로고
    • Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks
    • Kobayashi H, Sakurai T, Imai M, Takahashi N, Fukuda A, Yayoi O, et al. Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet. 2012;8:e1002440.
    • (2012) Plos Genet , vol.8
    • Kobayashi, H.1    Sakurai, T.2    Imai, M.3    Takahashi, N.4    Fukuda, A.5    Yayoi, O.6
  • 32
    • 84857331867 scopus 로고    scopus 로고
    • Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
    • Xie W, Barr CL, Kim A, Yue F, Lee AY, Eubanks J, et al. Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell. 2012;148:816-31.
    • (2012) Cell , vol.148 , pp. 816-831
    • Xie, W.1    Barr, C.L.2    Kim, A.3    Yue, F.4    Lee, A.Y.5    Eubanks, J.6
  • 33
    • 84875467145 scopus 로고    scopus 로고
    • Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development
    • Ichiyanagi T, Ichiyanagi K, Miyake M, Sasaki H. Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development. Nucleic Acids Res. 2013;41:738-45.
    • (2013) Nucleic Acids Res , vol.41 , pp. 738-745
    • Ichiyanagi, T.1    Ichiyanagi, K.2    Miyake, M.3    Sasaki, H.4
  • 34
    • 84988375135 scopus 로고    scopus 로고
    • 5-hydroxymethylcytosine: A new insight into epigenetics in cancer
    • Ye C, Li L. 5-hydroxymethylcytosine: a new insight into epigenetics in cancer. Cancer Biol Ther. 2014;15:10-5.
    • (2014) Cancer Biol Ther , vol.15 , pp. 10-15
    • Ye, C.1
  • 35
    • 84879672635 scopus 로고    scopus 로고
    • Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis
    • Gan H, Wen L, Liao S, Lin X, Ma T, Liu J, et al. Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Nat Commun. 2013;4:1995.
    • (2013) Nat Commun , vol.4 , pp. 1995
    • Gan, H.1    Wen, L.2    Liao, S.3    Lin, X.4    Ma, T.5    Liu, J.6
  • 36
    • 84927124824 scopus 로고    scopus 로고
    • Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia
    • Wang XX, Sun BF, Jiao J, Chong ZC, Chen YS, Wang XL, et al. Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia. Oncotarget. 2015;6:6535-43.
    • (2015) Oncotarget , vol.6 , pp. 6535-6543
    • Wang, X.X.1    Sun, B.F.2    Jiao, J.3    Chong, Z.C.4    Chen, Y.S.5    Wang, X.L.6
  • 37
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • Razin A, Riggs AD. DNA methylation and gene function. Science. 1980;210:604-10.
    • (1980) Science , vol.210 , pp. 604-610
    • Razin, A.1    Riggs, A.D.2
  • 38
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 1997;25:2532-34.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 40
    • 4444346815 scopus 로고    scopus 로고
    • De novo quantitative bisulfite sequencing using the pyrosequencing technology
    • Dupont JM, Tost J, Jammes H, Gut IG. De novo quantitative bisulfite sequencing using the pyrosequencing technology. Anal Biochem. 2004;333:119-27.
    • (2004) Anal Biochem , vol.333 , pp. 119-127
    • Dupont, J.M.1    Tost, J.2    Jammes, H.3    Gut, I.G.4
  • 41
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
    • Frommer M, McDonald LE, Millar DS, Collis CM, Watt F, Grigg GW, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A. 1992;89:1827-31.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 1827-1831
    • Frommer, M.1    McDonald, L.E.2    Millar, D.S.3    Collis, C.M.4    Watt, F.5    Grigg, G.W.6
  • 42
    • 79951475133 scopus 로고    scopus 로고
    • A decade’s perspective on DNA sequencing technology
    • Mardis ER. A decade’s perspective on DNA sequencing technology. Nature. 2011;470:198-203.
    • (2011) Nature , vol.470 , pp. 198-203
    • Mardis, E.R.1
  • 43
    • 77249137168 scopus 로고    scopus 로고
    • Principles and challenges of genome wide DNA methylation analysis
    • Laird PW. Principles and challenges of genome wide DNA methylation analysis. Nat Rev Genet. 2010;11:191-203.
    • (2010) Nat Rev Genet , vol.11 , pp. 191-203
    • Laird, P.W.1
  • 45
    • 84866919003 scopus 로고    scopus 로고
    • Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging
    • Miura F, Enomoto Y, Dairiki R, Ito T. Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging. Nucleic Acids Res. 2012;40:e136.
    • (2012) Nucleic Acids Res , vol.40
    • Miura, F.1    Enomoto, Y.2    Dairiki, R.3    Ito, T.4
  • 46
    • 77649267695 scopus 로고    scopus 로고
    • Dynamic changes in the human methylome during differentiation
    • Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, et al. Dynamic changes in the human methylome during differentiation. Genome Res. 2010;20:320-31.
    • (2010) Genome Res , vol.20 , pp. 320-331
    • Laurent, L.1    Wong, E.2    Li, G.3    Huynh, T.4    Tsirigos, A.5    Ong, C.T.6
  • 47
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature. 2011;471:68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3    Hawkins, R.D.4    Nery, J.R.5    Hon, G.6
  • 48
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell. 2007; 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 51
    • 42449097684 scopus 로고    scopus 로고
    • Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro
    • Tachiwana H, Osakabe A, Kimura H, Kurumizaka H. Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro. Nucleic Acids Res. 2008;36:2208-18.
    • (2008) Nucleic Acids Res , vol.36 , pp. 2208-2218
    • Tachiwana, H.1    Osakabe, A.2    Kimura, H.3    Kurumizaka, H.4
  • 53
    • 80054752323 scopus 로고    scopus 로고
    • Emerging mass spectrometry-based technologies for analyses of chromatin changes: Analysis of histones and histone modifications
    • Shah B, Kozlowski RL, Han J, Borchers CH. Emerging mass spectrometry-based technologies for analyses of chromatin changes: analysis of histones and histone modifications. Methods Mol Biol. 2011;773:259-303.
    • (2011) Methods Mol Biol , vol.773 , pp. 259-303
    • Shah, B.1    Kozlowski, R.L.2    Han, J.3    Borchers, C.H.4
  • 54
    • 84884829249 scopus 로고    scopus 로고
    • Mapping human epigenomes
    • Rivera CM, Ren B. Mapping human epigenomes. Cell. 2013;155:39-55.
    • (2013) Cell , vol.155 , pp. 39-55
    • Rivera, C.M.1    Ren, B.2
  • 55
    • 84856385469 scopus 로고    scopus 로고
    • Human spermatozoal RNAs
    • Hamatani T. Human spermatozoal RNAs. Fertil Steril. 2012;97:275-81.
    • (2012) Fertil Steril , vol.97 , pp. 275-281
    • Hamatani, T.1
  • 56
    • 77954572735 scopus 로고    scopus 로고
    • Long noncoding RNA as modular scaffold of histone modification complexes
    • Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science. 2010;329:689-93.
    • (2010) Science , vol.329 , pp. 689-693
    • Tsai, M.C.1    Manor, O.2    Wan, Y.3    Mosammaparast, N.4    Wang, J.K.5    Lan, F.6
  • 57
    • 79551527596 scopus 로고    scopus 로고
    • Spermatozoal RNA, profiling towards a clinical evaluation of sperm quality
    • Hamatani T. Spermatozoal RNA, profiling towards a clinical evaluation of sperm quality. Reprod Biomed Online. 2011;22:103-5.
    • (2011) Reprod Biomed Online , vol.22 , pp. 103-105
    • Hamatani, T.1
  • 58
    • 84901712439 scopus 로고    scopus 로고
    • MicroRNAs and spermatogenesis
    • Kotaja N. MicroRNAs and spermatogenesis. Fertil Steril. 2014;101:1552-62.
    • (2014) Fertil Steril , vol.101 , pp. 1552-1562
    • Kotaja, N.1
  • 59
    • 80755187797 scopus 로고    scopus 로고
    • Genomic imprinting: A mammalian epigenetic discovery model
    • Barlow DP. Genomic imprinting: a mammalian epigenetic discovery model. Annu Rev Genet. 2011;45:379-403.
    • (2011) Annu Rev Genet , vol.45 , pp. 379-403
    • Barlow, D.P.1
  • 61
    • 12244264222 scopus 로고    scopus 로고
    • Fetal origins of adult disease: Strength of effects and biological basis
    • Barker DJ, Eriksson JG, Forsén T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol. 2002;31:1235-39.
    • (2002) Int J Epidemiol , vol.31 , pp. 1235-1239
    • Barker, D.J.1    Eriksson, J.G.2    Forsén, T.3    Osmond, C.4
  • 62
    • 84856401866 scopus 로고    scopus 로고
    • Epigenetics of the male gamete
    • Carrell DT. Epigenetics of the male gamete. Fertil Steril. 2012;97:267-74.
    • (2012) Fertil Steril , vol.97 , pp. 267-274
    • Carrell, D.T.1
  • 63
    • 32244439227 scopus 로고    scopus 로고
    • Male gamete contributions to the embryo
    • Yanagimachi R. Male gamete contributions to the embryo. Ann N Y Acad Sci. 2005;1061:203-7.
    • (2005) Ann N Y Acad Sci , vol.1061 , pp. 203-207
    • Yanagimachi, R.1
  • 64
    • 33745255403 scopus 로고    scopus 로고
    • Protamines and male infertility
    • Oliva R. Protamines and male infertility. Hum Reprod Update. 2006;12:417-35.
    • (2006) Hum Reprod Update , vol.12 , pp. 417-435
    • Oliva, R.1
  • 66
    • 1842834345 scopus 로고    scopus 로고
    • Expression of hyperacetylated histone H4 during normal and impaired human spermatogenesis
    • Sonnack V, Failing K, Bergmann M, Steger K. Expression of hyperacetylated histone H4 during normal and impaired human spermatogenesis. Andrologia. 2002;34:384-90.
    • (2002) Andrologia , vol.34 , pp. 384-390
    • Sonnack, V.1    Failing, K.2    Bergmann, M.3    Steger, K.4
  • 69
    • 0034940263 scopus 로고    scopus 로고
    • Altered protamine 2 expression is uncommon in donors of known fertility, but common among men with poor fertilizing capacity, and may reflect other abnormalities of spermiogenesis
    • Carrell DT, Liu L. Altered protamine 2 expression is uncommon in donors of known fertility, but common among men with poor fertilizing capacity, and may reflect other abnormalities of spermiogenesis. J Androl. 2001;22:604-10.
    • (2001) J Androl , vol.22 , pp. 604-610
    • Carrell, D.T.1    Liu, L.2
  • 70
    • 77957194585 scopus 로고    scopus 로고
    • Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility
    • Hammoud SS, Purwar J, Pflueger C, Cairns BR, Carrell DT. Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility. Fertil Steril. 2010;94:1728-33.
    • (2010) Fertil Steril , vol.94 , pp. 1728-1733
    • Hammoud, S.S.1    Purwar, J.2    Pflueger, C.3    Cairns, B.R.4    Carrell, D.T.5
  • 71
    • 0031977267 scopus 로고    scopus 로고
    • Detection of p2 precursors in the sperm cells of infertile patients who have reduced protamine p2 levels
    • de Yebra L, Ballesca JL, Vanrell JA, Corzett M, Balhorn R, Oliva R. Detection of p2 precursors in the sperm cells of infertile patients who have reduced protamine p2 levels. Fertil Steril. 1998;69:755-59.
    • (1998) Fertil Steril , vol.69 , pp. 755-759
    • De Yebra, L.1    Ballesca, J.L.2    Vanrell, J.A.3    Corzett, M.4    Balhorn, R.5    Oliva, R.6
  • 74
    • 33745258535 scopus 로고    scopus 로고
    • Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients
    • Torregrosa N, Domínguez-Fandos D, Camejo MI, Shirley CR, Meistrich ML, Ballescà JL, et al. Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients. Hum Reprod. 2006;21:2084-89.
    • (2006) Hum Reprod , vol.21 , pp. 2084-2089
    • Torregrosa, N.1    Domínguez-Fandos, D.2    Camejo, M.I.3    Shirley, C.R.4    Meistrich, M.L.5    Ballescà, J.L.6
  • 75
    • 34347213437 scopus 로고    scopus 로고
    • Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells
    • Oakes CC, la Salle S, Smiraglia DJ, Robaire B, Trasler JM. Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells. Dev Biol. 2007;307:368-79.
    • (2007) Dev Biol , vol.307 , pp. 368-379
    • Oakes, C.C.1    La Salle, S.2    Smiraglia, D.J.3    Robaire, B.4    Trasler, J.M.5
  • 76
    • 0023030892 scopus 로고
    • Marked differences in the ability of distinct protamines to disassemble nucleosomal core particles in vitro
    • Oliva R, Mezquita C. Marked differences in the ability of distinct protamines to disassemble nucleosomal core particles in vitro. Biochemistry. 1986;25:6508-11.
    • (1986) Biochemistry , vol.25 , pp. 6508-6511
    • Oliva, R.1    Mezquita, C.2
  • 77
    • 77956897397 scopus 로고    scopus 로고
    • Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm
    • Navarro-Costa P, Nogueira P, Carvalho M, Leal F, Cordeiro I, Calhaz-Jorge C, et al. Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm. Hum Reprod. 2010;25:2647-54.
    • (2010) Hum Reprod , vol.25 , pp. 2647-2654
    • Navarro-Costa, P.1    Nogueira, P.2    Carvalho, M.3    Leal, F.4    Cordeiro, I.5    Calhaz-Jorge, C.6
  • 78
    • 84867031187 scopus 로고    scopus 로고
    • Novel insights into DNA methylation features in spermatozoa: Stability and peculiarities
    • Krausz C, Sandoval J, Sayols S, Chianese C, Giachini C, Heyn H, et al. Novel insights into DNA methylation features in spermatozoa: stability and peculiarities. PLoS ONE. 2012;7:e44479.
    • (2012) Plos ONE , vol.7
    • Krausz, C.1    Sandoval, J.2    Sayols, S.3    Chianese, C.4    Giachini, C.5    Heyn, H.6
  • 79
    • 77955101583 scopus 로고    scopus 로고
    • Testis transcriptome analysis in male infertility: New insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion
    • Gatta V, Raicu F, Ferlin A, Antonucci I, Scioletti AP, Garolla A, et al. Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion. BMC Genomics. 2010;11:401.
    • (2010) BMC Genomics , vol.11 , pp. 401
    • Gatta, V.1    Raicu, F.2    Ferlin, A.3    Antonucci, I.4    Scioletti, A.P.5    Garolla, A.6
  • 80
    • 44949259146 scopus 로고    scopus 로고
    • Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm
    • Houshdaran S, Cortessis VK, Siegmund K, Yang A, Laird PW, Sokol RZ. Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm. PLoS ONE. 2007;2:e1289.
    • (2007) Plos ONE , vol.2
    • Houshdaran, S.1    Cortessis, V.K.2    Siegmund, K.3    Yang, A.4    Laird, P.W.5    Sokol, R.Z.6
  • 81
    • 35448975719 scopus 로고    scopus 로고
    • Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients
    • Kobayashi H, Sato A, Otsu E, Hiura H, Tomatsu C, Utsunomiya T, et al. Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. Hum Mol Genet. 2007;16:2542-51.
    • (2007) Hum Mol Genet , vol.16 , pp. 2542-2551
    • Kobayashi, H.1    Sato, A.2    Otsu, E.3    Hiura, H.4    Tomatsu, C.5    Utsunomiya, T.6
  • 82
    • 40049100483 scopus 로고    scopus 로고
    • Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia
    • Marques CJ, Costa P, Vaz B, Carvalho F, Fernandes S, Barros A, et al. Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia. Mol Hum Reprod. 2008;14:67-74.
    • (2008) Mol Hum Reprod , vol.14 , pp. 67-74
    • Marques, C.J.1    Costa, P.2    Vaz, B.3    Carvalho, F.4    Fernandes, S.5    Barros, A.6
  • 83
    • 68949208601 scopus 로고    scopus 로고
    • MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: The role of epigenetics in male infertility
    • Khazamipour N, Noruzinia M, Fatehmanesh P, Keyhanee M, Pujol P. MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility. Hum Reprod. 2009;24:2361-64.
    • (2009) Hum Reprod , vol.24 , pp. 2361-2364
    • Khazamipour, N.1    Noruzinia, M.2    Fatehmanesh, P.3    Keyhanee, M.4    Pujol, P.5
  • 84
    • 77954416527 scopus 로고    scopus 로고
    • Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1
    • Poplinski A, Tüttelmann F, Kanber D, Horsthemke B, Gromoll J. Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1. Int J Androl. 2010;33:642-49.
    • (2010) Int J Androl , vol.33 , pp. 642-649
    • Poplinski, A.1    Tüttelmann, F.2    Kanber, D.3    Horsthemke, B.4    Gromoll, J.5
  • 85
    • 78649730409 scopus 로고    scopus 로고
    • Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR)
    • Wu W, Shen O, Qin Y, Niu X, Lu C, Xia Y, et al. Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR). PLoS ONE. 2010;5:e13884.
    • (2010) Plos ONE , vol.5
    • Wu, W.1    Shen, O.2    Qin, Y.3    Niu, X.4    Lu, C.5    Xia, Y.6
  • 86
    • 79957524930 scopus 로고    scopus 로고
    • Epigenetics, spermatogenesis and male infertility
    • Rajender S, Avery K, Agarwal A. Epigenetics, spermatogenesis and male infertility. Mutat Res. 2011;727:62-71.
    • (2011) Mutat Res , vol.727 , pp. 62-71
    • Rajender, S.1    Avery, K.2    Agarwal, A.3
  • 87
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet. 2002;3:662-73.
    • (2002) Nat Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 88
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: A landscape takes shape
    • Goldberg AD, Allis CD, Bernstein E. Epigenetics: a landscape takes shape. Cell. 2007;128:635-38.
    • (2007) Cell , vol.128 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 89
    • 84888866019 scopus 로고    scopus 로고
    • Epigenetics in fertilization and preimplantation embryo development
    • Rivera RM, Ross JW. Epigenetics in fertilization and preimplantation embryo development. Prog Biophys Mol Biol. 2013;113:423-32.
    • (2013) Prog Biophys Mol Biol , vol.113 , pp. 423-432
    • Rivera, R.M.1    Ross, J.W.2
  • 90
    • 0025802792 scopus 로고
    • Decrease in DNA methylase activity during preimplantation development in the mouse
    • Monk M, Adams RL, Rinaldi A. Decrease in DNA methylase activity during preimplantation development in the mouse. Development. 1991;112:189-92.
    • (1991) Development , vol.112 , pp. 189-192
    • Monk, M.1    Adams, R.L.2    Rinaldi, A.3
  • 91
    • 67650083483 scopus 로고    scopus 로고
    • Epigenetic regulation in mammalian preimplantation embryo development
    • Shi L, Wu J. Epigenetic regulation in mammalian preimplantation embryo development. Reprod Biol Endocrinol. 2009;7:59.
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 59
    • Shi, L.1    Wu, J.2
  • 93
    • 0034598784 scopus 로고    scopus 로고
    • Embryogenesis: Demethylation of the zygotic paternal genome
    • Mayer W, Niveleau A, Walter J, Fundele R, Haaf T. Embryogenesis: demethylation of the zygotic paternal genome. Nature. 2000;403:501-2.
    • (2000) Nature , vol.403 , pp. 501-502
    • Mayer, W.1    Niveleau, A.2    Walter, J.3    Fundele, R.4    Haaf, T.5
  • 94
  • 96
    • 0021139979 scopus 로고
    • Cell lineage-specific undermethylation of mouse repetitive DNA
    • Chapman V, Forrester L, Sanford J, Hastie N, Rossant J. Cell lineage-specific undermethylation of mouse repetitive DNA. Nature. 1984;307:284-86.
    • (1984) Nature , vol.307 , pp. 284-286
    • Chapman, V.1    Forrester, L.2    Sanford, J.3    Hastie, N.4    Rossant, J.5
  • 97
    • 0022965187 scopus 로고
    • Undermethylation of structural gene sequences in extraembryonic lineages of the mouse
    • Rossant J, Sanford JP, Chapman VM, Andrews GK. Undermethylation of structural gene sequences in extraembryonic lineages of the mouse. Dev Biol. 1986;117:567-73.
    • (1986) Dev Biol , vol.117 , pp. 567-573
    • Rossant, J.1    Sanford, J.P.2    Chapman, V.M.3    Rews, G.K.4
  • 99
    • 0037172659 scopus 로고    scopus 로고
    • Mitotically stable association of polycomb group proteins and Enx1 with the inactive X chromosome in trophoblast stem cells
    • Mak W, Baxter J, Silva J, Newall AE, Otte AP, Brockdorff N. Mitotically stable association of polycomb group proteins and Enx1 with the inactive X chromosome in trophoblast stem cells. Curr Biol. 2004;12:1016-20.
    • (2004) Curr Biol , vol.12 , pp. 1016-1020
    • Mak, W.1    Baxter, J.2    Silva, J.3    Newall, A.E.4    Otte, A.P.5    Brockdorff, N.6
  • 100
    • 0942268864 scopus 로고    scopus 로고
    • Epigenetic dynamics of imprinted X inactivation during early mouse development
    • Okamoto I, Otte AP, Allis CD, Reinberg D, Heard E. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science. 2004;303:644-49.
    • (2004) Science , vol.303 , pp. 644-649
    • Okamoto, I.1    Otte, A.P.2    Allis, C.D.3    Reinberg, D.4    Heard, E.5
  • 101
    • 58549109636 scopus 로고    scopus 로고
    • X chromosome dosage compensation: How mammals keep the balance
    • Payer B, Lee JT. X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet. 2008;42:733-72.
    • (2008) Annu Rev Genet , vol.42 , pp. 733-772
    • Payer, B.1    Lee, J.T.2
  • 103
    • 0033562954 scopus 로고    scopus 로고
    • Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis
    • Davis TL, Trasler JM, Moss SB, Yang GJ, Bartolomei MS. Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis. Genomics. 1999;58:18-28.
    • (1999) Genomics , vol.58 , pp. 18-28
    • Davis, T.L.1    Trasler, J.M.2    Moss, S.B.3    Yang, G.J.4    Bartolomei, M.S.5
  • 104
    • 0034703865 scopus 로고    scopus 로고
    • The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development
    • Davis TL, Yang GJ, McCarrey JR, Bartolomei MS. The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development. Hum Mol Genet. 2000;9:2885-94.
    • (2000) Hum Mol Genet , vol.9 , pp. 2885-2894
    • Davis, T.L.1    Yang, G.J.2    McCarrey, J.R.3    Bartolomei, M.S.4
  • 105
    • 7944221225 scopus 로고    scopus 로고
    • Timing of establishment of paternal methylation imprints in the mouse
    • Li JY, Lees-Murdock DJ, Xu GL, Walsh CP. Timing of establishment of paternal methylation imprints in the mouse. Genomics. 2004;84:952-60.
    • (2004) Genomics , vol.84 , pp. 952-960
    • Li, J.Y.1    Lees-Murdock, D.J.2    Xu, G.L.3    Walsh, C.P.4
  • 106
    • 33750202016 scopus 로고    scopus 로고
    • Towards a better understanding of RNA carriage by ejaculate spermatozoa
    • Miller D, Ostermeier GC. Towards a better understanding of RNA carriage by ejaculate spermatozoa. Hum Reprod Update. 2006;12:757-67.
    • (2006) Hum Reprod Update , vol.12 , pp. 757-767
    • Miller, D.1    Ostermeier, G.C.2
  • 107
    • 38449108054 scopus 로고    scopus 로고
    • Ensuring continuity of the paternal genome: Potential roles for spermatozoal RNA in mammalian embryogenesis
    • Miller D. Ensuring continuity of the paternal genome: potential roles for spermatozoal RNA in mammalian embryogenesis. Soc Reprod Fertil Suppl. 2007;65:373-89.
    • (2007) Soc Reprod Fertil Suppl , vol.65 , pp. 373-389
    • Miller, D.1
  • 109
  • 110
    • 77649209897 scopus 로고    scopus 로고
    • The human sperm epigenome and its potential role in embryonic development
    • Carrell DT, Hammoud SS. The human sperm epigenome and its potential role in embryonic development. Mol Hum Reprod. 2010;16:37-47.
    • (2010) Mol Hum Reprod , vol.16 , pp. 37-47
    • Carrell, D.T.1    Hammoud, S.S.2
  • 111
    • 80051949165 scopus 로고    scopus 로고
    • Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men
    • Hammoud SS, Nix DA, Hammoud AO, Gibson M, Cairns BR, Carrell DT. Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men. Hum Reprod. 2011;26:2558-69.
    • (2011) Hum Reprod , vol.26 , pp. 2558-2569
    • Hammoud, S.S.1    Nix, D.A.2    Hammoud, A.O.3    Gibson, M.4    Cairns, B.R.5    Carrell, D.T.6
  • 112
    • 84865208871 scopus 로고    scopus 로고
    • Rate of de novo mutations and the importance of father’s age to disease risk
    • Kong A, Frigge ML, Masson G, Besenbacher S, Sulem P, Magnusson G, et al. Rate of de novo mutations and the importance of father’s age to disease risk. Nature. 2012;488:471-5.
    • (2012) Nature , vol.488 , pp. 471-475
    • Kong, A.1    Frigge, M.L.2    Masson, G.3    Besenbacher, S.4    Sulem, P.5    Magnusson, G.6
  • 113
    • 77649211158 scopus 로고    scopus 로고
    • Function of sperm chromatin structural elements in fertilization and development
    • Ward WS. Function of sperm chromatin structural elements in fertilization and development. Mol Hum Reprod. 2010;16:30-6.
    • (2010) Mol Hum Reprod , vol.16 , pp. 30-36
    • Ward, W.S.1
  • 114
  • 115
    • 84875179383 scopus 로고    scopus 로고
    • Epigenetic concerns in assisted reproduction: Update and critical review of the current literature
    • Shufaro Y, Laufer N. Epigenetic concerns in assisted reproduction: update and critical review of the current literature. Fertil Steril. 2013;99:605-6.
    • (2013) Fertil Steril , vol.99 , pp. 605-606
    • Shufaro, Y.1    Laufer, N.2
  • 116
    • 0014800017 scopus 로고
    • Viability and growth of mouse embryos after in vitro culture and fusion
    • Bowman P, McLaren A. Viability and growth of mouse embryos after in vitro culture and fusion. J Embryol Exp Morphol. 1970;23:693-704.
    • (1970) J Embryol Exp Morphol , vol.23 , pp. 693-704
    • Bowman, P.1    McLaren, A.2
  • 117
  • 118
    • 0031844174 scopus 로고    scopus 로고
    • Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: Association with aberrant phenotypes
    • Dean W, Bowden L, Aitchison A, Klose J, Moore T, Meneses JJ, et al. Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes. Development. 1998;125:2273-82.
    • (1998) Development , vol.125 , pp. 2273-2282
    • Dean, W.1    Bowden, L.2    Aitchison, A.3    Klose, J.4    Moore, T.5    Meneses, J.J.6
  • 119
    • 0034112603 scopus 로고    scopus 로고
    • Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo
    • Doherty AS, Mann MR, Tremblay KD, Bartolomei MS, Schultz RM. Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo. Biol Reprod. 2000;62:1526-35.
    • (2000) Biol Reprod , vol.62 , pp. 1526-1535
    • Doherty, A.S.1    Mann, M.R.2    Tremblay, K.D.3    Bartolomei, M.S.4    Schultz, R.M.5
  • 120
    • 0035116489 scopus 로고    scopus 로고
    • Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes
    • Khosla S, Dean W, Brown D, Reik W, Feil R. Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes. Biol Reprod. 2001;64:918-26.
    • (2001) Biol Reprod , vol.64 , pp. 918-926
    • Khosla, S.1    Dean, W.2    Brown, D.3    Reik, W.4    Feil, R.5
  • 121
    • 0031768294 scopus 로고    scopus 로고
    • Large offspring syndrome in cattle and sheep
    • Young LE, Sinclair KD, Wilmut I. Large offspring syndrome in cattle and sheep. Rev Reprod. 1998;3:155-63.
    • (1998) Rev Reprod , vol.3 , pp. 155-163
    • Young, L.E.1    Sinclair, K.D.2    Wilmut, I.3
  • 123
    • 0345275966 scopus 로고    scopus 로고
    • Conservation of IGF2-H19 and IGF2R imprinting in sheep: Effects of somatic cell nuclear transfer
    • Young LE, Schnieke AE, McCreath KJ, Wieckowski S, Konfortova G, Fernandes K, et al. Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer. Mech Dev. 2003;120:1433-42.
    • (2003) Mech Dev , vol.120 , pp. 1433-1442
    • Young, L.E.1    Schnieke, A.E.2    McCreath, K.J.3    Wieckowski, S.4    Konfortova, G.5    Fernandes, K.6
  • 124
    • 0037939678 scopus 로고    scopus 로고
    • Rare congenital disorders, imprinted genes, and assisted reproductive technology
    • Gosden R, Trasler J, Lucifero D, Faddy M. Rare congenital disorders, imprinted genes, and assisted reproductive technology. Lancet. 2003;361:1975-77.
    • (2003) Lancet , vol.361 , pp. 1975-1977
    • Gosden, R.1    Trasler, J.2    Lucifero, D.3    Faddy, M.4
  • 125
    • 0037222510 scopus 로고    scopus 로고
    • Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19
    • DeBaun MR, Niemitz EL, Feinberg AP. Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19. Am J Hum Genet. 2003;72:156-60.
    • (2003) Am J Hum Genet , vol.72 , pp. 156-160
    • Debaun, M.R.1    Niemitz, E.L.2    Feinberg, A.P.3
  • 126
    • 0038644577 scopus 로고    scopus 로고
    • In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene
    • Gicquel C, Gaston V, Mandelbaum J, Siffroi JP, Flahault A, Le Bouc Y. In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene. Am J Hum Genet. 2003; 72:1338-41.
    • (2003) Am J Hum Genet , vol.72 , pp. 1338-1341
    • Gicquel, C.1    Gaston, V.2    Mandelbaum, J.3    Siffroi, J.P.4    Flahault, A.5    Le Bouc, Y.6
  • 127
    • 0037035121 scopus 로고    scopus 로고
    • Low and very low birth weight in infants conceived with use of assisted reproductive technology
    • Schieve LA, Meikle SF, Ferre C, Peterson HB, Jeng G, Wilcox LS. Low and very low birth weight in infants conceived with use of assisted reproductive technology. N Engl J Med. 2002;346:731-37.
    • (2002) N Engl J Med , vol.346 , pp. 731-737
    • Schieve, L.A.1    Meikle, S.F.2    Ferre, C.3    Peterson, H.B.4    Jeng, G.5    Wilcox, L.S.6
  • 128
    • 70349573301 scopus 로고    scopus 로고
    • DNA methylation and gene expression differences in children conceived in vitro or in vivo
    • Katari S, Turan N, Bibikova M, Erinle O, Chalian R, Foster M, et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet. 2009;18:3769-78.
    • (2009) Hum Mol Genet , vol.18 , pp. 3769-3778
    • Katari, S.1    Turan, N.2    Bibikova, M.3    Erinle, O.4    Chalian, R.5    Foster, M.6
  • 129
    • 34548733815 scopus 로고    scopus 로고
    • Delemarre-van de Waal HA. Body composition in children and adolescents born after in vitro fertilization or spontaneous conception
    • Ceelen M, van Weissenbruch MM, Roos JC, Vermeiden JP, van Leeuwen FE, Delemarre-van de Waal HA. Body composition in children and adolescents born after in vitro fertilization or spontaneous conception. J Clin Endocrinol Metab. 2007;92:3417-23.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3417-3423
    • Ceelen, M.1    Van Weissenbruch, M.M.2    Roos, J.C.3    Vermeiden, J.P.4    Van Leeuwen, F.E.5
  • 130
    • 43249099254 scopus 로고    scopus 로고
    • Delemarre-Van de Waal HA. Cardiometabolic differences in children born after in vitro fertilization: Follow-up study
    • Ceelen M, van Weissenbruch MM, Vermeiden JP, van Leeuwen FE, Delemarre-Van de Waal HA. Cardiometabolic differences in children born after in vitro fertilization: follow-up study. J Clin Endocrinol Metab. 2008;93:1682-88.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1682-1688
    • Ceelen, M.1    Van Weissenbruch, M.M.2    Vermeiden, J.P.3    Van Leeuwen, F.E.4
  • 131
    • 70350493531 scopus 로고    scopus 로고
    • Growth during infancy and early childhood in relation to blood pressure and body fat measures at age 8-18 years of IVF children and spontaneously conceived controls born to subfertile parents
    • Ceelen M, van Weissenbruch MM, Prein J, Smit JJ, Vermeiden JP, Spreeuwenberg M, et al. Growth during infancy and early childhood in relation to blood pressure and body fat measures at age 8-18 years of IVF children and spontaneously conceived controls born to subfertile parents. Hum Reprod. 2009;24:2788-95.
    • (2009) Hum Reprod , vol.24 , pp. 2788-2795
    • Ceelen, M.1    Van Weissenbruch, M.M.2    Prein, J.3    Smit, J.J.4    Vermeiden, J.P.5    Spreeuwenberg, M.6
  • 132
    • 80054076295 scopus 로고    scopus 로고
    • Does in vitro fertilisation increase type 2 diabetes and cardiovascular risk?
    • Chen M, Norman RJ, Heilbronn LK. Does in vitro fertilisation increase type 2 diabetes and cardiovascular risk? Curr Diabetes Rev. 2011;7:426-32.
    • (2011) Curr Diabetes Rev , vol.7 , pp. 426-432
    • Chen, M.1    Norman, R.J.2    Heilbronn, L.K.3
  • 133
    • 1842435262 scopus 로고    scopus 로고
    • Epigenetics and assisted reproductive technology: A call for investigation
    • Niemitz EL, Feinberg AP. Epigenetics and assisted reproductive technology: a call for investigation. Am J Hum Genet. 2004;74:599-609.
    • (2004) Am J Hum Genet , vol.74 , pp. 599-609
    • Niemitz, E.L.1    Feinberg, A.P.2
  • 134
    • 34247465595 scopus 로고    scopus 로고
    • Could epigenetics play a role in the developmental origins of health and disease?
    • Cutfield WS, Hofman PL, Mitchell M, Morison IM. Could epigenetics play a role in the developmental origins of health and disease? Pediatr Res. 2007;61:68R-75R.
    • (2007) Pediatr Res , vol.61 , pp. 68R-75R
    • Cutfield, W.S.1    Hofman, P.L.2    Mitchell, M.3    Morison, I.M.4
  • 135
    • 66349111107 scopus 로고    scopus 로고
    • Perturbation of genomic imprinting in oligozoospermia
    • Filipponi D, Feil R. Perturbation of genomic imprinting in oligozoospermia. Epigenetics. 2009;4:27-30.
    • (2009) Epigenetics , vol.4 , pp. 27-30
    • Filipponi, D.1    Feil, R.2
  • 136
    • 70450252294 scopus 로고    scopus 로고
    • DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm
    • Kobayashi H, Hiura H, John RM, Sato A, Otsu E, Kobayashi N, et al. DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm. Eur J Hum Genet. 2009;17:1582-91.
    • (2009) Eur J Hum Genet , vol.17 , pp. 1582-1591
    • Kobayashi, H.1    Hiura, H.2    John, R.M.3    Sato, A.4    Otsu, E.5    Kobayashi, N.6
  • 137
    • 84887100939 scopus 로고    scopus 로고
    • Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: Assessment of genetic variants and assisted reproductive technology outcome
    • Montjean D, Ravel C, Benkhalifa M, Cohen-Bacrie P, Berthaut I, Bashamboo A, et al. Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: assessment of genetic variants and assisted reproductive technology outcome. Fertil Steril. 2013;100:1241-47.
    • (2013) Fertil Steril , vol.100 , pp. 1241-1247
    • Montjean, D.1    Ravel, C.2    Benkhalifa, M.3    Cohen-Bacrie, P.4    Berthaut, I.5    Bashamboo, A.6
  • 140
    • 84923555788 scopus 로고    scopus 로고
    • Environmental epigenetic inheritance through gametes and implications for human reproduction
    • Wei Y, Schatten H, Sun QY. Environmental epigenetic inheritance through gametes and implications for human reproduction. Hum Reprod Update 2014
    • (2014) Hum Reprod Update
    • Wei, Y.1    Schatten, H.2    Sun, Q.Y.3
  • 141
    • 34548456881 scopus 로고    scopus 로고
    • Dietary histone deacetylase inhibitors: From cells to mice to man
    • Dashwood R, Ho E. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin Cancer Biol. 2007;17:363-69.
    • (2007) Semin Cancer Biol , vol.17 , pp. 363-369
    • Dashwood, R.1    Ho, E.2
  • 142
    • 82755189770 scopus 로고    scopus 로고
    • Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung
    • Izzotti A, Larghero P, Longobardi M, Cartiglia C, Camoirano A, Steele VE, et al. Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung. Mutat Res. 2011;717:9-16.
    • (2011) Mutat Res , vol.717 , pp. 9-16
    • Izzotti, A.1    Larghero, P.2    Longobardi, M.3    Cartiglia, C.4    Camoirano, A.5    Steele, V.E.6
  • 143
    • 67749129297 scopus 로고    scopus 로고
    • Epigenetics and environmental chemicals
    • Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr. 2009;21:243-51.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 243-251
    • Baccarelli, A.1    Bollati, V.2
  • 144
  • 145
    • 84896722288 scopus 로고    scopus 로고
    • A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line
    • Soubry A, Hoyo C, Jirtle RL, Murphy SK. A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. Bioessays. 2014;36:359-71.
    • (2014) Bioessays , vol.36 , pp. 359-371
    • Soubry, A.1    Hoyo, C.2    Jirtle, R.L.3    Murphy, S.K.4
  • 147
    • 82955195660 scopus 로고    scopus 로고
    • Parental occupational exposure to exhausts, solvents, glues and paints, and risk of childhood leukemia
    • Reid A, Glass DC, Bailey HD, Milne E, Armstrong BK, Alvaro F, et al. Parental occupational exposure to exhausts, solvents, glues and paints, and risk of childhood leukemia. Cancer Causes Control. 2011;22:1575-85.
    • (2011) Cancer Causes Control , vol.22 , pp. 1575-1585
    • Reid, A.1    Glass, D.C.2    Bailey, H.D.3    Milne, E.4    Armstrong, B.K.5    Alvaro, F.6
  • 148
    • 33751533712 scopus 로고    scopus 로고
    • Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease
    • Anway MD, Leathers C, Skinner MK. Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology. 2006;147:5515-23.
    • (2006) Endocrinology , vol.147 , pp. 5515-5523
    • Anway, M.D.1    Leathers, C.2    Skinner, M.K.3
  • 149
    • 84871714992 scopus 로고    scopus 로고
    • Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers
    • Guerrero-Bosagna C, Covert TR, Haque MM, Settles M, Nilsson EE, Anway MD, et al. Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers. Reprod Toxicol. 2012;34:694-707.
    • (2012) Reprod Toxicol , vol.34 , pp. 694-707
    • Guerrero-Bosagna, C.1    Covert, T.R.2    Haque, M.M.3    Settles, M.4    Nilsson, E.E.5    Anway, M.D.6
  • 151
    • 84876163688 scopus 로고    scopus 로고
    • Epigenetics in radiation biology: A new research frontier
    • Merrifield M, Kovalchuk O. Epigenetics in radiation biology: a new research frontier. Front Genet. 2013;4:40.
    • (2013) Front Genet , vol.4 , pp. 40
    • Merrifield, M.1    Kovalchuk, O.2
  • 152
    • 33947310031 scopus 로고    scopus 로고
    • Environtal epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK. Environtal epigenomics and disease susceptibility. Nat Rev Genet. 2007;8:253-62.
    • (2007) Nat Rev Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 153
    • 75149150268 scopus 로고    scopus 로고
    • Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm
    • Stouder C, Paoloni-Giacobino A. Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm. Reproduction. 2010;139:373-79.
    • (2010) Reproduction , vol.139 , pp. 373-379
    • Stouder, C.1    Paoloni-Giacobino, A.2
  • 154
    • 78650446334 scopus 로고    scopus 로고
    • Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals
    • Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, et al. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 2010;143:1084-96.
    • (2010) Cell , vol.143 , pp. 1084-1096
    • Carone, B.R.1    Fauquier, L.2    Habib, N.3    Shea, J.M.4    Hart, C.E.5    Li, R.6
  • 155
    • 84906088773 scopus 로고    scopus 로고
    • In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism
    • Radford EJ, Ito M, Shi H, Corish JA, Yamazawa K, Isganaitis E, et al. In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism. Science. 2014;345:1255903.
    • (2014) Science , vol.345
    • Radford, E.J.1    Ito, M.2    Shi, H.3    Corish, J.A.4    Yamazawa, K.5    Isganaitis, E.6
  • 156
    • 77958596171 scopus 로고    scopus 로고
    • Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
    • Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature. 2010;467:963-66.
    • (2010) Nature , vol.467 , pp. 963-966
    • Ng, S.F.1    Lin, R.C.2    Laybutt, D.R.3    Barres, R.4    Owens, J.A.5    Morris, M.J.6
  • 157
    • 84885151895 scopus 로고    scopus 로고
    • Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content
    • Fullston T, Ohlsson Teague EM, Palmer NO, Deblasio MJ, Mitchell M, Corbett M, et al. Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content. FASEB J. 2013;27:4226-43.
    • (2013) FASEB J , vol.27 , pp. 4226-4243
    • Fullston, T.1    Ohlsson Teague, E.M.2    Palmer, N.O.3    Deblasio, M.J.4    Mitchell, M.5    Corbett, M.6
  • 158
    • 21944442058 scopus 로고    scopus 로고
    • Prenatal exposure to the Dutch famine and disease in later life: An overview
    • Painter RC, Roseboom TJ, Bleker OP. Prenatal exposure to the Dutch famine and disease in later life: an overview. Reprod Toxicol. 2005;20:345-52.
    • (2005) Reprod Toxicol , vol.20 , pp. 345-352
    • Painter, R.C.1    Roseboom, T.J.2    Bleker, O.P.3
  • 161
    • 70349999407 scopus 로고    scopus 로고
    • DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific
    • Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, et al. DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific. Hum Mol Genet. 2009;18:4046-53.
    • (2009) Hum Mol Genet , vol.18 , pp. 4046-4053
    • Tobi, E.W.1    Lumey, L.H.2    Talens, R.P.3    Kremer, D.4    Putter, H.5    Stein, A.D.6
  • 162
    • 84923326770 scopus 로고    scopus 로고
    • DNA methylation signatures link prenatal famine exposure to growth and metabolism
    • Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, et al. DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nat Commun. 2014;5:5592.
    • (2014) Nat Commun , vol.5 , pp. 5592
    • Tobi, E.W.1    Goeman, J.J.2    Monajemi, R.3    Gu, H.4    Putter, H.5    Zhang, Y.6
  • 163
    • 0035034911 scopus 로고    scopus 로고
    • Longevity determined by paternal ancestors’ nutrition during their slow growth period
    • Bygren LO, Kaati G, Edvinsson S. Longevity determined by paternal ancestors’ nutrition during their slow growth period. Acta Biotheor. 2001;49:53-9.
    • (2001) Acta Biotheor , vol.49 , pp. 53-59
    • Bygren, L.O.1    Kaati, G.2    Edvinsson, S.3
  • 164
    • 0036862451 scopus 로고    scopus 로고
    • Cardiovascular and diabetes mortality determined by nutrition during parents’ and grandparents’ slow growth period
    • Kaati G, Bygren LO, Edvinsson S. Cardiovascular and diabetes mortality determined by nutrition during parents’ and grandparents’ slow growth period. Eur J Hum Genet. 2002;10:682-88.
    • (2002) Eur J Hum Genet , vol.10 , pp. 682-688
    • Kaati, G.1    Bygren, L.O.2    Edvinsson, S.3
  • 165
    • 34250781054 scopus 로고    scopus 로고
    • Transgenerational response to nutrition, early life circumstances and longevity
    • Kaati G, Bygren LO, Pembrey M, Sjöström M. Transgenerational response to nutrition, early life circumstances and longevity. Eur J Hum Genet. 2007;15:784-90.
    • (2007) Eur J Hum Genet , vol.15 , pp. 784-790
    • Kaati, G.1    Bygren, L.O.2    Pembrey, M.3    Sjöström, M.4
  • 167
    • 84894273971 scopus 로고    scopus 로고
    • Change in paternal grandmothers early food supply influenced cardiovascular mortality of the female grandchildren
    • Bygren LO, Tinghög P, Carstensen J, Edvinsson S, Kaati G, Pembrey ME, et al. Change in paternal grandmothers early food supply influenced cardiovascular mortality of the female grandchildren. BMC Genet. 2014;15:12.
    • (2014) BMC Genet , vol.15 , pp. 12
    • Bygren, L.O.1    Tinghög, P.2    Carstensen, J.3    Edvinsson, S.4    Kaati, G.5    Pembrey, M.E.6
  • 168
    • 84892833124 scopus 로고    scopus 로고
    • You are what you eat, and so are your children: The impact of micronutrients on the epigenetic programming of offspring
    • Vanhees K, Vonhögen IG, van Schooten FJ, Godschalk RW. You are what you eat, and so are your children: the impact of micronutrients on the epigenetic programming of offspring. Cell Mol Life Sci. 2014;71:271-85.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 271-285
    • Vanhees, K.1    Vonhögen, I.G.2    Van Schooten, F.J.3    Godschalk, R.W.4
  • 169
    • 84920084310 scopus 로고    scopus 로고
    • Human second-trimester amniotic fluid cells are able to create embryoid body-like structures “in vitro” and to show typical expression profiles of embryonic and primordial germ cells
    • Antonucci I, Di Pietro R, Alfonsi M, Centurione MA, Centurione L, Sancilio S, et al. Human second-trimester amniotic fluid cells are able to create embryoid body-like structures “in vitro” and to show typical expression profiles of embryonic and primordial germ cells. Cell Transplant. 2014;23:1501-15.
    • (2014) Cell Transplant , vol.23 , pp. 1501-1515
    • Antonucci, I.1    Di Pietro, R.2    Alfonsi, M.3    Centurione, M.A.4    Centurione, L.5    Sancilio, S.6
  • 170
    • 84905454836 scopus 로고    scopus 로고
    • Age-associated sperm DNA methylation alterations: Possible implications in offspring disease susceptibility
    • Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT. Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility. PLoS Genet. 2014;10:e1004458.
    • (2014) Plos Genet , vol.10
    • Jenkins, T.G.1    Aston, K.I.2    Pflueger, C.3    Cairns, B.R.4    Carrell, D.T.5
  • 171
    • 84903289499 scopus 로고    scopus 로고
    • Identification of genomic features in environmentally induced epigenetic transgenerational inherited sperm epimutations
    • Guerrero-Bosagna C, Weeks S, Skinner MK. Identification of genomic features in environmentally induced epigenetic transgenerational inherited sperm epimutations. PLoS ONE. 2014;9:e100194.
    • (2014) Plos ONE , vol.9
    • Guerrero-Bosagna, C.1    Weeks, S.2    Skinner, M.K.3
  • 172
    • 84906100296 scopus 로고    scopus 로고
    • Parenting from before conception
    • Lane M, Robker RL, Robertson SA. Parenting from before conception. Science. 2014;345:756-60.
    • (2014) Science , vol.345 , pp. 756-760
    • Lane, M.1    Robker, R.L.2    Robertson, S.A.3
  • 173
    • 27944465772 scopus 로고    scopus 로고
    • Seminal plasma and male factor signalling in the female reproductive tract
    • Robertson SA. Seminal plasma and male factor signalling in the female reproductive tract. Cell Tissue Res. 2005;322:43-52.
    • (2005) Cell Tissue Res , vol.322 , pp. 43-52
    • Robertson, S.A.1
  • 175
    • 84895893232 scopus 로고    scopus 로고
    • Epigenetics: The sins of the father
    • Hughes V. Epigenetics: the sins of the father. Nature. 2014;507:22-4.
    • (2014) Nature , vol.507 , pp. 22-24
    • Hughes, V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.