Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia

Oncotarget

Volumn 6, Issue 9, 2015, Pages 6535-6543

  Wang, Xiu Xia ^a   Sun, Bao Fa ^b   Jiao, Jiao ^a   Chong, Ze Chen ^b   Chen, Yu Shen ^b   Wang, Xiao Li ^b   Zhao, Yue ^a,c   Zhou, Yi Ming ^d   Li, Da ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Chinese Academy of Sciences   (China)

^c BEIJING HOSPITAL   (China)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

5 hydroxymethylcytosine; Epigenetic; Genomic imprinting; Globozoospermia

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA;

ARTICLE; CELL STRUCTURE; CHEMICAL LABELING; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; EPIGENETICS; GAMETE; GDAP1L1 GENE; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GLOBOZOOSPERMIA; GNAS GENE; INTRON; KCNK9 GENE; LIN28B GENE; MALE INFERTILITY; MOLECULAR PATHOLOGY; PHENOTYPE; RB1 GENE; RTL1 GENE; SEQUENCE ANALYSIS; SLC22A18 GENE; SPERMATOGENESIS; SPERMATOZOON MOTILITY; ZDBF2 GENE; ANALOGS AND DERIVATIVES; CASE CONTROL STUDY; CELL SHAPE; CHEMISTRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; GENOME IMPRINTING; GENOME-WIDE ASSOCIATION STUDY; HUMAN; MALE; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; SPERMATOZOON;

CASE-CONTROL STUDIES; CELL SHAPE; CYTOSINE; DNA; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOMIC IMPRINTING; HUMANS; INFERTILITY, MALE; MALE; PHENOTYPE; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA;

EID: 84927124824     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3163     Document Type: Article

References (22)

1. Dam AH, Feenstra I, Westphal JR, Ramos L, van Golde RJ, Kremer JA. Globozoospermia revisited. Hum Reprod Update. 2007; 13:63-75.
2. Gu TP, Guo F, Yang H, Wu HP, Xu GF, Liu W, Xie ZG, Shi L, He X, Jin SG, Iqbal K, Shi YG, Deng Z, et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. 2011; 477:606-610.
3. Moradan S, Yousefi B. Globozoospermia syndrome: two case reports. J Med Liban. 2014; 62:183-185.
4. Pirrello O, Machev N, Schimdt F, Terriou P, Menezo Y, Viville S. Search for mutations involved in human globozoospermia. Hum Reprod. 2005; 20:1314-1318.
5. Nakamura T, Liu YJ, Nakashima H, Umehara H, Inoue K, Matoba S, Tachibana M, Ogura A, Shinkai Y, Nakano T. PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature. 2012; 486:415-419.
6. Ye C, Li L. 5hydroxymethylcytosine: a new insight into epigenetics in cancer. Cancer Biol Ther. 2014; 15:10-5.
7. Gan H, Wen L, Liao S, Lin X, Ma T, Liu J, Song CX, Wang M, He C, Han C, Tang F. Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Nat Commun. 2013; 4:1995.
8. Globisch D, Münzel M, Müller M, Michalakis S, Wagner M, Koch S, Brückl T, Biel M, Carell T. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One. 2010; 5:e15367.
9. Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science. 2012; 336:934-937.
10. Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 2011; 473:394-397.
11. Laurentino S, Beygo J, Nordhoff V, Kliesch S, Wistuba J, Borgmann J, Buiting K, Horsthemke B, Gromoll J. Epigenetic germline mosaicism in infertile men. Hum Mol Genet. 2014; in press.
12. Molaro A, Hodges E, Fang F, Song Q, McCombie WR, Hannon GJ, Smith AD. Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell. 2011; 146:1029-1041.
13. Irier H, Street RC, Dave R, Lin L, Cai C, Davis TH, Yao B, Cheng Y, Jin P. Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus. Genomics. 2014; 104:376-382.
14. Colquitt BM, Allen WE, Barnea G, Lomvardas S. Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity. Proc Natl Acad Sci U S A. 2013; 110:14682-14687.
15. Tang KQ, Yang WC, Zhang XX, Yang LG. Effects of polymorphisms in the bovine growth differentiation factor 9 gene on sperm quality in Holstein bulls. Genet Mol Res. 2013; 12:2189-2195.
16. Botezatu A, Socolov R, Socolov D, Iancu IV, Anton G. Methylation pattern of methylene tetrahydrofolate reductase and small nuclear ribonucleoprotein polypeptide N promoters in oligoasthenospermia: a case-control study. Reprod Biomed Online. 2014; 28:225-231.
17. Ihara K, Nishimura T, Fukuda T, Ookura T, Nishimori K. Generation of venus reporter knock-in mice revealed MAGI-2 expression patterns in adult mice. Gene Expr Patterns. 2012; 12:95-101.
18. Hu W, Gauthier L, Baibakov B, JimenezMovilla M, DeanJ. FIGLA, a basic helixloophelix transcription factor, balances sexually dimorphic gene expression in postnatal oocytes. Mol Cell Biol. 2010; 30:3661-3671.
19. Li H, Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics. 2009; 25:1754-1760.
20. Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS. Modelbased analysis of ChIPSeq (MACS). Genome Biol. 2008; 9:R137.
21. Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009; 4:44-57.
22. Smoot ME, Ono K, Ruscheinski J, Wang PL, Ideker T. Cytoscape 2, new features for data integration and network visualization. Bioinformatics. 2011; 27:431-432.