Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of pierre Robin sequence

Development (Cambridge)

Volumn 142, Issue 21, 2015, Pages 3734-3745

  Parada, Carolina ^a   Han, Dong ^a   Grimaldi, Alexandre ^a   Sarrion, Patricia ^a   Park, Shery S ^a   Pelikan, Richard ^a   Sanchez Lara, Pedro A ^a,b,c   Chai, Yang ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Cleft palate; ERK pathway; Glossoptosis; Mandibular asymmetry; Micrognathia; Neural crest cells; Pierre Robin sequence

Indexed keywords

COLLAGEN TYPE 1; CRE RECOMBINASE; LINK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOD1 PROTEIN; MYOGENIN; ODD SKIPPED RELATED TRANSCIPTION FACTOR 2; RNA; SCLERAXIS; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MYF 6; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL ACTIVITY; CELL COUNT; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHONDROGENESIS; CLEFT PALATE; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; DISEASE SEVERITY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FEMALE; GENE DELETION; GENE DISRUPTION; GENE MUTATION; GLOSSOPTOSIS; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXILLA HYPOPLASIA; MESENCHYME CELL; MICROGNATHIA; MOUSE; MUSCLE DEVELOPMENT; MUSCLE DISEASE; NEURAL CREST; NEURAL CREST CELL; NEWBORN; NONHUMAN; PHENOTYPE; PIERRE ROBIN SYNDROME; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RNA ANALYSIS; SIGNAL TRANSDUCTION; ABNORMALITIES; ANIMAL; EMBRYOLOGY; GENETICS; METABOLISM; PATHOLOGY; TONGUE;

ANIMALS; CLEFT PALATE; FEMALE; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; NEURAL CREST; PIERRE ROBIN SYNDROME; TONGUE;

EID: 84946594232     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.125328     Document Type: Article

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