Recurrent Coding Sequence Variation Explains only A Small Fraction of the Genetic Architecture of Colorectal Cancer

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Timofeeva, Maria N ^a   Kinnersley, Ben ^b   Farrington, Susan M ^a   Whiffin, Nicola ^b   Palles, Claire ^c   Svinti, Victoria ^a   Lloyd, Amy ^b   Gorman, Maggie ^c   Ooi, Li Yin ^a   Hosking, Fay ^b   Barclay, Ella ^c   Zgaga, Lina ^a   Dobbins, Sara ^b   Martin, Lynn ^c   Theodoratou, Evropi ^a   Broderick, Peter ^b   Tenesa, Albert ^a,d   Smillie, Claire ^a   Grimes, Graeme ^a   Hayward, Caroline ^a   Campbell, Archie ^a   Porteous, David ^a   Deary, Ian J ^a   Harris, Sarah E ^a   Northwood, Emma L ^e   Barrett, Jennifer H ^e   Smith, Gillian ^f   Wolf, Roland ^f   Forman, David ^g   Morreau, Hans ^h   Ruano, Dina ^h   Tops, Carli ^h   Wijnen, Juul ^h   Schrumpf, Melanie ^h   Boot, Arnoud ^h   Vasen, Hans F A ^h   Hes, Frederik J ^h   Van Wezel, Tom ^h   Franke, Andre ⁱ   Lieb, Wolgang ^j   Schafmayer, Clemens ⁱ   Hampe, Jochen ^k   Buch, Stephan ^k   Propping, Peter ^l   Hemminki, Kari ^m,n   Försti, Asta ^m,n   Westers, Helga ^o   Hofstra, Robert ^o,p   Pinheiro, Manuela ^q   Pinto, Carla ^q   Teixeira, Manuel ^q   Ruiz Ponte, Clara ^r   Fernández Rozadilla, Ceres ^c,r   Carracedo, Angel ^r   Castells, Antoni ^s   Castellví Bel, Sergi ^s   Campbell, Harry ^a   Bishop, D Timothy ^e   Tomlinson, Ian P M ^c   Dunlop, Malcolm G ^a   Houlston, Richard S ^b   more..

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^f UNIVERSITY OF DUNDEE   (United Kingdom)

^g INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^h LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁱ UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^j UNIVERSITY OF KIEL   (Germany)

^k UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^l UNIVERSITY HOSPITAL BONN   (Germany)

^m GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

ⁿ LUND UNIVERSITY   (Sweden)

^o UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^p ERASMUS MEDICAL CENTER   (Netherlands)

^q PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^r CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^s INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 1; ATF1 PROTEIN, HUMAN; CADHERIN; LNK PROTEIN, HUMAN; PROTEIN;

ALLELE; CASE CONTROL STUDY; CAUCASIAN; COLORECTAL TUMOR; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; ODDS RATIO; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ACTIVATING TRANSCRIPTION FACTOR 1; ALLELES; CADHERINS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS;

EID: 84946593635     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16286     Document Type: Article

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