Inhibition of calcineurin/NFAT pathway plays an essential role in renoprotective effect of tropisetron in early stage of diabetic nephropathy

European Journal of Pharmacology

Volumn 767, Issue , 2015, Pages 152-159

  Barzegar Fallah, Anita ^a,b   Alimoradi, Houman ^b   Razmi, Ali ^c   Dehpour, Ahmad Reza ^d   Asgari, Mojgan ^e   Shafiei, Massoumeh ^a  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c AVICENNA RESEARCH INSTITUTE   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Calcineurin; Diabetic nephropathy; Extracellular matrix; Glomerular hypertrophy; Tropisetron

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; FIBRONECTIN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; TROPISETRON; UNCLASSIFIED DRUG; CALCINEURIN INHIBITOR; CYCLOSPORIN; INDOLE DERIVATIVE; NFATC1 PROTEIN, RAT; PROTECTIVE AGENT; STREPTOZOCIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; GLOMERULUS FILTRATION RATE; HYPERGLYCEMIA; KIDNEY HYPERTROPHY; KIDNEY MASS; MALE; NONHUMAN; POLYURIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WEIGHT REDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DIABETIC NEPHROPATHIES; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GLOMERULUS; HYPERTROPHY; METABOLISM; PATHOLOGY;

ANIMALS; CALCINEURIN; CALCINEURIN INHIBITORS; CYCLOSPORINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; EXTRACELLULAR MATRIX; FIBRONECTINS; HYPERTROPHY; INDOLES; KIDNEY GLOMERULUS; MALE; PROTECTIVE AGENTS; RATS; STREPTOZOCIN; TRANSCRIPTION FACTORS;

EID: 84946547559     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.10.019     Document Type: Article

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