Differential regulation of glomerular arginine transporters (CAT-1 and CAT-2) in lipopolysaccharide-treated rats

American Journal of Physiology - Renal Physiology

Volumn 284, Issue 4 53-4, 2003, Pages

  Schwartz, Doron ^a   Schwartz, Idit F ^a   Gnessin, Ehud ^a   Wollman, Yoram ^a   Chernichovsky, Tamara ^a   Blum, Miriam ^a   Iaina, Adrian ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Arginine transport; Cationic amino acid transporter 2; Nitric oxide; Sepsis

Indexed keywords

7 NITROINDAZOLE; AMINO ACID TRANSPORTER; ARGININE; LIPOPOLYSACCHARIDE; MESSENGER RNA; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE SYNTHASE INHIBITOR;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; GENE CONTROL; GLOMERULUS FILTRATION RATE; MESANGIUM; MESANGIUM CELL; NONHUMAN; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; STEADY STATE; UPREGULATION;

EID: 0037376301     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00221.2002     Document Type: Article

References (34)

1. Albritton LM, Tseng L, Seadden D, and Cunningham JM. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57: 659-666, 1989.
2. Baylis C, Harton P, and Engles K. Endothelial derived relaxing factor controls renal hemodynamics in normal rat kidneys. J Am Soc Nephrol 1: 875-881, 1990.
3. Beasley D, Schwartz JH, and Brenner BM. Interleukin 1 induces prolonged L-arginine dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. J Clin Invest 87: 602-608, 1991.
4. Bone RC. The pathogenesis of sepsis. Ann Intern Med 115: 457-469, 1991.
5. Chomezynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
6. Closs EI, Graf P, Habermeier A, Cunningham JM, and Forsterman U. Human cationic amino acid transporters mCAT-1, mCAT-2A, and mCAT-2B: three related carriers with distinct transport properties. Biochemistry 36: 6462-6468, 1997.
7. Closs EI, Lyons CR, Kelly C, and Cunningham JM. Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of a domain that determines the transport properties of the MCAT proteins. J Biol Chem 268: 20796-20800, 1993.
8. De Nicola L, Blantz RC, and Gabbai FB. Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat. J Clin Invest 89: 1248-1256, 1992.
9. Durante W, Liao L, Iftikhar I, O'Brien W, and Schafer A. Differential regulation of L-arginine transport and nitric oxide production by vascular smooth muscle and endothelium. Circ Res 78: 1075-1082, 1996.
10. Gazzola GC, Dall' Asta V, Franchi-Gazzola R, and White MF. The cluster-tray method for rapid measurement of solute fluxes in adherent cultured cells. Anal Biochem 115: 368-374, 1981.
11. Granger DL, Hibbs JB Jr, Perfect JR, and Durack DT. Metabolic late of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest 85: 264-273, 1990.
12. Hattori Y, Kasai K, and Gross SS. Cationic amino acid transporter gene expression in cultured vascular smooth muscle cells and in rats. Am J Physiol Heart Circ Physiol 276: H2020-H2029, 1999.
13. Hosokawa H, Sawamura T, Kobayashi S, Ninomiya H, Miwa S, and Masaki T. Cloning and characterization of a brain-specific cationic amino acid transporter. J Biol Chem 272: 8717-8722, 1997.
14. Ito K and Groudine M. A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain. J Biol Chem 272: 26780-26786, 1997.
15. Iyengar R, Stuehr DJ, and Marletta MA. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst. Proc Natl Acad Sci USA 84: 6369-6373; 1987.
16. Jeffreys AJ, Wilson V, Neumann R, and Keyte J. Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells. Nucleic Acids Res 16: 10953-10971, 1988.
17. Kilbourn RG and Griffith OW. Overproduction of nitric oxide in cytokine-mediated and septic shock. J Natl Cancer Inst 84: 827-831, 1992.
18. Kim JW, Closs EI, Albritton LM, and Cunningham JM. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 352: 725-728, 1991.
19. + and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells. J Biol Chem 270: 27577-27583, 1995.
20. MacLeod CL, Finley K, Kakuda D, Kozak CA, and Wilkinson MF. Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor. Mol Cell Biol 10: 3663-3674, 1990.
21. McDonald KK, Zharikov S, Block ER, and Kilberg MS. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric oxide synthase may explain the "arginine paradox." J Biol Chem 272: 31213-31216, 1997.
22. Moore PK, Wallace P, Gaffen Z, Hart SL, and Babbedge RC. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol 110:219-224 1993.
23. Nicholson B, Manner CK, Kleeman J, and MacLeod CJ. Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J Biol Chem 276; 15881-15885, 2001.
24. Nicholson B, Sawamura T, Masaki T, and MacLeod CL. Increased Cat3-mediated cationic amino acid transport functionally compensates in Catl knockout cell lines. J Biol Chem 273: 14663-14666, 1998.
25. Sade K, Schwartz D, Wolman Y, Schwartz I, Chernichovski T, Blum M, Brazowski E, Keynan S, Raz I, Blantz RC, and Iaina A. Time eourse of lipopolysaccharide-induced nitric oxide synthase mRNA expression in rat glomeruli. J Lab Clin Med 134: 471-477, 1999.
26. Schwartz D, Mendonca M, Schwartz I, Xia Y, Satriano J, Wilson CB, and Blantz RC. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest 100: 439-448, 1997.
27. Schwartz IF, Schwartz D, Wollman Y, Chernichowski T, Blum M, Levo Y, and Iaina A. Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA. J Lab Clin Med 137:356-362, 2001.
28. Shultz PJ and Raij L. Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis. J Clin Invest 90: 1718-1725, 1992.
29. Simmons WW, Closs EI, Cunningham JM, Smith TW, and Kelly RA. Cytokines and insulin induce cationic amino acid transporter (CAT) in cardiac myocytes. Regulation of L-arginine transport and NO production by CAT-1, CAT-2A, and CAT-2B. J Biol Chem 271: 11694-11702, 1996.
30. Thiemermann C and Vane J. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharide in the rat in vivo. Eur J Pharmacol 182: 591-595, 1990.
31. Wang H, Kavanaugh MP, North RA, and Kabat D. Cell surface receptor for the ecotropic murine retroviruses is a basic amino acid. Nature 352: 729-731, 1991.
32. White MF and Christensen HN. The two-way flux of cationic amino acids across the plasma membrane of mammalian cells is largely explained by a single transport system. J Biol Chem 257: 4450-4457, 1982.
33. White MF, Gazzola GC, and Christensen HN. Cationic amino acid transport into cultured animal cells. I. Influx into cultured human fibroblasts. JBiol Chem 257: 4443-4449, 1982.
34. Wu F, Cholewa B, and Mattson DL. Characterization of L-arginine transporters in rat renal inner medullary collecting duct. Am J Physiol Regul Integr Comp Physiol 278: R1506-R1512, 2000.