Activity-Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists

Angewandte Chemie - International Edition

Volumn 54, Issue 46, 2015, Pages 13538-13544

  Karageorgis, George ^a   Dow, Mark ^a   Aimon, Anthony ^a   Warriner, Stuart ^a   Nelson, Adam ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

activity directed synthesis; agonists; bioactive molecules; carbenoids; reaction discovery

Indexed keywords

BIOACTIVITY; CHEMICAL COMPOUNDS; ENANTIOSELECTIVITY; MOLECULES;

AGONISTS; BIOACTIVE MOLECULES; CARBENOIDS; DIRECTED SYNTHESIS; REACTION DISCOVERY;

SYNTHESIS (CHEMICAL);

ANDROGEN; ANDROGEN RECEPTOR; AZO COMPOUND;

CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; SYNTHESIS;

ANDROGENS; AZO COMPOUNDS; MOLECULAR STRUCTURE; RECEPTORS, ANDROGEN;

EID: 84946494181     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201506944     Document Type: Article

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