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Volumn 31, Issue 7-8, 2015, Pages 901-907

Role of vitamin A in type 2 diabetes mellitus biology: Effects of intervention therapy in a deficient state

Author keywords

Oxidative stress; Retinoic acid; Retinol; Type 2 diabetes; Vitamin A

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; PROTEIN KINASE C; RETINOL; VITAMIN;

EID: 84946486230     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2014.12.014     Document Type: Review
Times cited : (44)

References (61)
  • 1
    • 82955247909 scopus 로고    scopus 로고
    • IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting D.R., Guariguata L., Weil C., Shaw J. IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diab Res Clin Pr 2011, 94:311-321.
    • (2011) Diab Res Clin Pr , vol.94 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 2
    • 0031445908 scopus 로고    scopus 로고
    • The rising global burden of diabetes and its complications: Estimates and projections to the year
    • Amos A., McCarty D., Zimmet P. The rising global burden of diabetes and its complications: Estimates and projections to the year. Diabetic Med 2010, 14:1-85.
    • (2010) Diabetic Med , vol.14 , pp. 1-85
    • Amos, A.1    McCarty, D.2    Zimmet, P.3
  • 3
    • 1542284225 scopus 로고    scopus 로고
    • Pathophysiology of type 2 diabetes
    • Scheen A.J. Pathophysiology of type 2 diabetes. Acta Clin Belg 2003, 58:335-341.
    • (2003) Acta Clin Belg , vol.58 , pp. 335-341
    • Scheen, A.J.1
  • 4
    • 4243062602 scopus 로고    scopus 로고
    • Candidate gene association study in type 2 diabetes indicates a role for genes involved in β-cell function as well as insulin action
    • Barroso I., Luan J., Middelberg R.P.S., Harding A.-H., Franks P.W., Jakes R.W., et al. Candidate gene association study in type 2 diabetes indicates a role for genes involved in β-cell function as well as insulin action. PLoS Biol 2003, 1:1-20.
    • (2003) PLoS Biol , vol.1 , pp. 1-20
    • Barroso, I.1    Luan, J.2    Middelberg, R.P.S.3    Harding, A.-H.4    Franks, P.W.5    Jakes, R.W.6
  • 5
    • 34249291282 scopus 로고    scopus 로고
    • Genetic predisposition to type 2 diabetes among Asian Indians
    • Radha V., Mohan V. Genetic predisposition to type 2 diabetes among Asian Indians. Indian J Med Res 2007, 125:259-274.
    • (2007) Indian J Med Res , vol.125 , pp. 259-274
    • Radha, V.1    Mohan, V.2
  • 6
    • 33845542745 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
    • Morino K., Petersen K.F., Shulman G.I. Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 2006, 55:9-15.
    • (2006) Diabetes , vol.55 , pp. 9-15
    • Morino, K.1    Petersen, K.F.2    Shulman, G.I.3
  • 7
    • 33645765312 scopus 로고    scopus 로고
    • Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress
    • Rolo A.P., Palmeira C.M. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharm 2006, 212:167-178.
    • (2006) Toxicol Appl Pharm , vol.212 , pp. 167-178
    • Rolo, A.P.1    Palmeira, C.M.2
  • 8
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans J.L., Goldfine I.D., Maddux B.A., Grodsky G.M. Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes. Endocr Rev 2002, 23:599-622.
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 9
    • 65249166998 scopus 로고    scopus 로고
    • The effect of hyperglycemia and oxidative stress on the development and progress of vascular complications in type 2 diabetes
    • Colak E., Singh N.M. The effect of hyperglycemia and oxidative stress on the development and progress of vascular complications in type 2 diabetes. Jugoslov Med Biochem 2009, 28:63-71.
    • (2009) Jugoslov Med Biochem , vol.28 , pp. 63-71
    • Colak, E.1    Singh, N.M.2
  • 10
    • 8644267972 scopus 로고    scopus 로고
    • Hyperglycemia-induced oxidative stress in diabetic complications
    • King G.L., Loeken G.M. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004, 122:333-338.
    • (2004) Histochem Cell Biol , vol.122 , pp. 333-338
    • King, G.L.1    Loeken, G.M.2
  • 11
    • 33646785085 scopus 로고    scopus 로고
    • The effect of hyperglycemia on the values of antioxidative parameters in type 2 diabetic patients with cardiovascular complications
    • Colak E., Singh N.M., Stankovic S., Dordevic P.B., Srekovic V.D., Lalic K., et al. The effect of hyperglycemia on the values of antioxidative parameters in type 2 diabetic patients with cardiovascular complications. Jugoslov Med Biochem 2006, 25:173-179.
    • (2006) Jugoslov Med Biochem , vol.25 , pp. 173-179
    • Colak, E.1    Singh, N.M.2    Stankovic, S.3    Dordevic, P.B.4    Srekovic, V.D.5    Lalic, K.6
  • 12
    • 80052894096 scopus 로고    scopus 로고
    • The effect of omega-3 fatty acids on serum paraoxonase activity, vitamins A, E, and C in type 2 diabetic patients
    • Kouchak A., Djalali M., Eshraghian M., Saedisomeolia A., Djazayery A., Hajianfar H. The effect of omega-3 fatty acids on serum paraoxonase activity, vitamins A, E, and C in type 2 diabetic patients. Res Med Sci 2011, 16:878-884.
    • (2011) Res Med Sci , vol.16 , pp. 878-884
    • Kouchak, A.1    Djalali, M.2    Eshraghian, M.3    Saedisomeolia, A.4    Djazayery, A.5    Hajianfar, H.6
  • 13
    • 0025732948 scopus 로고
    • Perspective in diabetes. Role of oxidative stress in development of complication in diabetes
    • Baynes J.W. Perspective in diabetes. Role of oxidative stress in development of complication in diabetes. Diabetes 1991, 40:405-441.
    • (1991) Diabetes , vol.40 , pp. 405-441
    • Baynes, J.W.1
  • 14
    • 0030906870 scopus 로고    scopus 로고
    • Antioxidants and human disease: a general introduction
    • Halliwell B. Antioxidants and human disease: a general introduction. Nutrition Rev 1997, 55:S44-S52.
    • (1997) Nutrition Rev , vol.55 , pp. S44-S52
    • Halliwell, B.1
  • 15
    • 75549083004 scopus 로고    scopus 로고
    • Antioxidant antiinflammatory treatment in type 2 diabetes
    • Ceriello A., Testa R. Antioxidant antiinflammatory treatment in type 2 diabetes. Diab Care 2009, 32:S232-S236.
    • (2009) Diab Care , vol.32 , pp. S232-S236
    • Ceriello, A.1    Testa, R.2
  • 17
    • 20944436002 scopus 로고    scopus 로고
    • Advances in diabetes for the millennium: vitamins and oxidant stress in diabetes and its complications
    • Chertow B. Advances in diabetes for the millennium: vitamins and oxidant stress in diabetes and its complications. Med Gen Med 2004, 6:4.
    • (2004) Med Gen Med , vol.6 , pp. 4
    • Chertow, B.1
  • 18
    • 0029867614 scopus 로고    scopus 로고
    • Benefits and liabilities of vitamin A and carotenoids
    • Olson J.A. Benefits and liabilities of vitamin A and carotenoids. J Nutr 1996, 126:1208S-1212S.
    • (1996) J Nutr , vol.126 , pp. 1208S-1212S
    • Olson, J.A.1
  • 19
    • 0028808923 scopus 로고
    • High retinol/retinol-binding protein ratio in noninsulin-dependent diabetes mellitus
    • Sasaki H., Iwasaki T., Kato S., Tada N. High retinol/retinol-binding protein ratio in noninsulin-dependent diabetes mellitus. Am J Med Sci 1995, 310:177-182.
    • (1995) Am J Med Sci , vol.310 , pp. 177-182
    • Sasaki, H.1    Iwasaki, T.2    Kato, S.3    Tada, N.4
  • 20
    • 0033916009 scopus 로고    scopus 로고
    • The metabolic availability of vitamin A is decreased at the onset of diabetes in BB rats
    • Lu J., Dixon W.T., Tsin A.T.C., Basu T.K. The metabolic availability of vitamin A is decreased at the onset of diabetes in BB rats. Diabetes J Nutr 2000, 130:1958-1962.
    • (2000) Diabetes J Nutr , vol.130 , pp. 1958-1962
    • Lu, J.1    Dixon, W.T.2    Tsin, A.T.C.3    Basu, T.K.4
  • 21
    • 84878236825 scopus 로고    scopus 로고
    • The malnutrition of obesity: micronutrient deficiencies that promote diabetes
    • Via M. The malnutrition of obesity: micronutrient deficiencies that promote diabetes. ISRN Endocrinology 2012, 2012:103472.
    • (2012) ISRN Endocrinology , vol.2012 , pp. 103472
    • Via, M.1
  • 22
    • 84864628320 scopus 로고    scopus 로고
    • Retinoid metabolism and diabetes mellitus
    • Rhee E.-J., Plutzky J. Retinoid metabolism and diabetes mellitus. Diabetes Metab J 2012, 36:167-180.
    • (2012) Diabetes Metab J , vol.36 , pp. 167-180
    • Rhee, E.-J.1    Plutzky, J.2
  • 25
    • 0000553729 scopus 로고    scopus 로고
    • Vitamin A
    • Williams & Wilkins, Baltimore, M. Shils, J.A. Olson, M. Shike, A.C. Ross (Eds.)
    • Ross A.C. Vitamin A. Modern nutrition in health and disease 1999, 305-313. Williams & Wilkins, Baltimore. 9th ed. M. Shils, J.A. Olson, M. Shike, A.C. Ross (Eds.).
    • (1999) Modern nutrition in health and disease , pp. 305-313
    • Ross, A.C.1
  • 26
    • 21744435965 scopus 로고    scopus 로고
    • Controlling nuclear receptors: the circular logic of cofactor cycles
    • Perissi V., Rosenfeld M.G. Controlling nuclear receptors: the circular logic of cofactor cycles. Cell Biol 2005, 6:542-554.
    • (2005) Cell Biol , vol.6 , pp. 542-554
    • Perissi, V.1    Rosenfeld, M.G.2
  • 27
    • 0018730497 scopus 로고
    • Cellular retinol- and retinoic acid-binding proteins in vitamin A action
    • Chytil F., Ong D.E. Cellular retinol- and retinoic acid-binding proteins in vitamin A action. Fed Proc 1979, 38:2510-2514.
    • (1979) Fed Proc , vol.38 , pp. 2510-2514
    • Chytil, F.1    Ong, D.E.2
  • 28
    • 3543131311 scopus 로고    scopus 로고
    • Vitamin A deficiency impairs fetal islet development and causes subsequent glucose intolerance in adult rats
    • Matthews K.A., Rhoten W.B., Driscoll H.K., Chertow B.S. Vitamin A deficiency impairs fetal islet development and causes subsequent glucose intolerance in adult rats. J Nutr 2004, 134:1958-1963.
    • (2004) J Nutr , vol.134 , pp. 1958-1963
    • Matthews, K.A.1    Rhoten, W.B.2    Driscoll, H.K.3    Chertow, B.S.4
  • 29
    • 78649556651 scopus 로고    scopus 로고
    • Beta-carotene is an important vitamin A source for humans
    • Grune T., Lietz G., Palou A., Ross A.C., Stahl W., Tang G., et al. Beta-carotene is an important vitamin A source for humans. J Nutr 2010, 140:2268S-2285S.
    • (2010) J Nutr , vol.140 , pp. 2268S-2285S
    • Grune, T.1    Lietz, G.2    Palou, A.3    Ross, A.C.4    Stahl, W.5    Tang, G.6
  • 30
    • 0032698617 scopus 로고    scopus 로고
    • Vitamin A antagonizes the action of vitamin D in rats
    • Rohde C.M., Manatt M., Clagett-Dame M., DeLuca H.F. Vitamin A antagonizes the action of vitamin D in rats. J Nutr 1999, 129:2246-2250.
    • (1999) J Nutr , vol.129 , pp. 2246-2250
    • Rohde, C.M.1    Manatt, M.2    Clagett-Dame, M.3    DeLuca, H.F.4
  • 31
    • 84946485449 scopus 로고    scopus 로고
    • Low-income Americans and racial and ethnic minorities experience disproportionately higher rates of disease
    • US Med, July
    • Low-income Americans and racial and ethnic minorities experience disproportionately higher rates of disease. US Med, July 2009.
    • (2009)
  • 32
    • 0033305606 scopus 로고    scopus 로고
    • Effect of retinoic acid on glucokinase activity and gene expression and on insulin secretion in primary cultures of pancreatic islets
    • Cabrera-Valladares G., German M.S., Matschinsky F.M., Wang J., Fernandez-Mejia C. Effect of retinoic acid on glucokinase activity and gene expression and on insulin secretion in primary cultures of pancreatic islets. Endocrinology 1999, 140:3091-3096.
    • (1999) Endocrinology , vol.140 , pp. 3091-3096
    • Cabrera-Valladares, G.1    German, M.S.2    Matschinsky, F.M.3    Wang, J.4    Fernandez-Mejia, C.5
  • 33
    • 0029143061 scopus 로고
    • Identification and characterization of a functional retinoic acid/thyroid hormone-response element upstream of the human insulin gene enhancer
    • Clark A.R., Wilson M.E., London N.J., James R.F., Docherty K. Identification and characterization of a functional retinoic acid/thyroid hormone-response element upstream of the human insulin gene enhancer. Biochem J 1995, 309(Pt 3):863-870.
    • (1995) Biochem J , vol.309 , pp. 863-870
    • Clark, A.R.1    Wilson, M.E.2    London, N.J.3    James, R.F.4    Docherty, K.5
  • 34
    • 76149121171 scopus 로고    scopus 로고
    • Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis
    • Perez R.A., Hoyos B., Zhao F., Vinogradov V., Fischman D.A., Harris R.A., et al. Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis. FASEB J 2010, 24:627-636.
    • (2010) FASEB J , vol.24 , pp. 627-636
    • Perez, R.A.1    Hoyos, B.2    Zhao, F.3    Vinogradov, V.4    Fischman, D.A.5    Harris, R.A.6
  • 35
    • 84860584916 scopus 로고    scopus 로고
    • Retinoic acid upregulates preadipocyte genes to block adipogenesis and suppress diet-induced obesity
    • Berry D.C., DeSantis D., Soltanian H., Croniger C.M., Noy N. Retinoic acid upregulates preadipocyte genes to block adipogenesis and suppress diet-induced obesity. Diabetes 2012, 61:1112-1121.
    • (2012) Diabetes , vol.61 , pp. 1112-1121
    • Berry, D.C.1    DeSantis, D.2    Soltanian, H.3    Croniger, C.M.4    Noy, N.5
  • 37
    • 67651087413 scopus 로고    scopus 로고
    • The plasma retinol levels as pro-oxidant/oxidant agents in haemodialysis patients
    • Roehrs M., Valentini J., Bulcao R., Biesaski H. The plasma retinol levels as pro-oxidant/oxidant agents in haemodialysis patients. Nephrol Dial Transplant 2009, 1-7.
    • (2009) Nephrol Dial Transplant , pp. 1-7
    • Roehrs, M.1    Valentini, J.2    Bulcao, R.3    Biesaski, H.4
  • 38
    • 0037405021 scopus 로고    scopus 로고
    • Regulation of the cardiac mitochondrial membrane potential by retinoids
    • Korichneva I., Waka J., Hammerling U. Regulation of the cardiac mitochondrial membrane potential by retinoids. JPET 2003, 305:426-433.
    • (2003) JPET , vol.305 , pp. 426-433
    • Korichneva, I.1    Waka, J.2    Hammerling, U.3
  • 39
    • 0037341238 scopus 로고    scopus 로고
    • Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad and the glutathione connection
    • Robertson R.P., Harmon J., Tran P.O., Tanaka Y., Takahashi H. Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad and the glutathione connection. Diabetes 2003, 52:581-587.
    • (2003) Diabetes , vol.52 , pp. 581-587
    • Robertson, R.P.1    Harmon, J.2    Tran, P.O.3    Tanaka, Y.4    Takahashi, H.5
  • 40
    • 34948828965 scopus 로고    scopus 로고
    • Rapid, non-genomic actions of retinoic acid on phosphatidyl-inositol-3-kinase signaling pathway mediated by the retinoic acid receptor
    • Masia S., Alvarez S., de Lera A.R., Barettino D. Rapid, non-genomic actions of retinoic acid on phosphatidyl-inositol-3-kinase signaling pathway mediated by the retinoic acid receptor. Mol Endocrinol 2007, 21:2391-2402.
    • (2007) Mol Endocrinol , vol.21 , pp. 2391-2402
    • Masia, S.1    Alvarez, S.2    de Lera, A.R.3    Barettino, D.4
  • 41
    • 27744536990 scopus 로고    scopus 로고
    • Human UDP-Glucuronosyltransferase 1 A5: identification, expression, and activity
    • Finel M., Li X., Stephen D.G., Bratton S., Mackenzie P.I., Pandya A.R. Human UDP-Glucuronosyltransferase 1 A5: identification, expression, and activity. JPET 2005, 315:1143-1149.
    • (2005) JPET , vol.315 , pp. 1143-1149
    • Finel, M.1    Li, X.2    Stephen, D.G.3    Bratton, S.4    Mackenzie, P.I.5    Pandya, A.R.6
  • 42
    • 33749342069 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85
    • Draznin B. Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85. Diabetes 2006, 55:2392-2397.
    • (2006) Diabetes , vol.55 , pp. 2392-2397
    • Draznin, B.1
  • 44
    • 33846848897 scopus 로고    scopus 로고
    • Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents
    • Lee D.C., Lee J.W., Im J.A. Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents. Metabolism 2007, 56:327-331.
    • (2007) Metabolism , vol.56 , pp. 327-331
    • Lee, D.C.1    Lee, J.W.2    Im, J.A.3
  • 46
    • 33746846631 scopus 로고    scopus 로고
    • Chronic dietary vitamin A supplementation regulates obesity in an obese mutant wnin/ob rat model
    • Jeyakumar S.M., Vajreswari A., Giridharan N.V. Chronic dietary vitamin A supplementation regulates obesity in an obese mutant wnin/ob rat model. Obesity 2006, 14:52-59.
    • (2006) Obesity , vol.14 , pp. 52-59
    • Jeyakumar, S.M.1    Vajreswari, A.2    Giridharan, N.V.3
  • 47
    • 4644317876 scopus 로고    scopus 로고
    • Effect of retinoic acid on leptin, glycerol, and glucose levels in mature rat adipocytes in vitro
    • Hong S.E., Ahn I.S., Jung H.S., Rayner D.V., Do M.S. Effect of retinoic acid on leptin, glycerol, and glucose levels in mature rat adipocytes in vitro. J Med Food 2004, 7:320-326.
    • (2004) J Med Food , vol.7 , pp. 320-326
    • Hong, S.E.1    Ahn, I.S.2    Jung, H.S.3    Rayner, D.V.4    Do, M.S.5
  • 48
    • 33947165199 scopus 로고    scopus 로고
    • Impact of vitamin A on high-density lipoprotein-cholesterol and scavenger receptor class bi in the obese rat
    • Jeyakumar S.M., Vajreswari A., Giridharan N.V. Impact of vitamin A on high-density lipoprotein-cholesterol and scavenger receptor class bi in the obese rat. Obesity 2007, 15:322-329.
    • (2007) Obesity , vol.15 , pp. 322-329
    • Jeyakumar, S.M.1    Vajreswari, A.2    Giridharan, N.V.3
  • 49
    • 79952056053 scopus 로고    scopus 로고
    • Vitamin A metabolism and adipose tissue biology
    • Frey S.K., Vogel S. Vitamin A metabolism and adipose tissue biology. Nutrients 2011, 3:27-39.
    • (2011) Nutrients , vol.3 , pp. 27-39
    • Frey, S.K.1    Vogel, S.2
  • 50
    • 1842582779 scopus 로고    scopus 로고
    • Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines
    • Wu L., Nicholson W., Knobel S.M., Steffner R.J., May J.M., Piston D.W., et al. Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines. J Biol Chem 2004, 13:12126-12134.
    • (2004) J Biol Chem , vol.13 , pp. 12126-12134
    • Wu, L.1    Nicholson, W.2    Knobel, S.M.3    Steffner, R.J.4    May, J.M.5    Piston, D.W.6
  • 51
    • 0037368259 scopus 로고    scopus 로고
    • Retinol-induced apoptosis in larval pancreas of Bufo bufo
    • Accordi F., Chimenti C. Retinol-induced apoptosis in larval pancreas of Bufo bufo. J Anat 2003, 202:309-314.
    • (2003) J Anat , vol.202 , pp. 309-314
    • Accordi, F.1    Chimenti, C.2
  • 53
    • 55549139488 scopus 로고    scopus 로고
    • Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation
    • Chiu H.J., Fischman D.A., Hammerling U. Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation. FASEB J 2008, 22:3878-3887.
    • (2008) FASEB J , vol.22 , pp. 3878-3887
    • Chiu, H.J.1    Fischman, D.A.2    Hammerling, U.3
  • 54
    • 67649211584 scopus 로고    scopus 로고
    • All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor β/δ and retinoic acid receptor
    • Berry D.C., Noy N. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor β/δ and retinoic acid receptor. Mol Cell Biol 2009, 29:3286-3296.
    • (2009) Mol Cell Biol , vol.29 , pp. 3286-3296
    • Berry, D.C.1    Noy, N.2
  • 55
    • 84897571463 scopus 로고    scopus 로고
    • Prevalence of vitamin A deficiency in South Asia: causes, outcomes, and possible remedies
    • Akhtar S., Ahmed A., Randhawa M.A., Atukorala S., Arlappa N., Ismail T., et al. Prevalence of vitamin A deficiency in South Asia: causes, outcomes, and possible remedies. J Health Popul Nutr 2013, 31:413-423.
    • (2013) J Health Popul Nutr , vol.31 , pp. 413-423
    • Akhtar, S.1    Ahmed, A.2    Randhawa, M.A.3    Atukorala, S.4    Arlappa, N.5    Ismail, T.6
  • 56
    • 22244474890 scopus 로고    scopus 로고
    • Effects of vitamin A supplementation on immune responses and correlation with clinical outcomes
    • Villamor E., Fawzi W.W. Effects of vitamin A supplementation on immune responses and correlation with clinical outcomes. Clin Microbiol Rev 2005, 18:446-464.
    • (2005) Clin Microbiol Rev , vol.18 , pp. 446-464
    • Villamor, E.1    Fawzi, W.W.2
  • 57
    • 0030820868 scopus 로고    scopus 로고
    • Vitamin A homeostasis and diabetes mellitus
    • Basu T.K., Basualdo C. Vitamin A homeostasis and diabetes mellitus. Nutrition 1997, 13:804-806.
    • (1997) Nutrition , vol.13 , pp. 804-806
    • Basu, T.K.1    Basualdo, C.2
  • 58
    • 33644856918 scopus 로고    scopus 로고
    • The acute and chronic toxic effects of vitamin
    • Penniston K.L., Tanumihardjo S.A. The acute and chronic toxic effects of vitamin. Am J Clin Nutr 2006, 83:191-201.
    • (2006) Am J Clin Nutr , vol.83 , pp. 191-201
    • Penniston, K.L.1    Tanumihardjo, S.A.2
  • 59
    • 84865666683 scopus 로고    scopus 로고
    • Retinoids modulate the effect of PTH and calcitriol on EGF receptor expression in UMR 106-01 cells
    • González E.A., Martin K.J. Retinoids modulate the effect of PTH and calcitriol on EGF receptor expression in UMR 106-01 cells. Calcif Tissue Int 1996, 58:429-434.
    • (1996) Calcif Tissue Int , vol.58 , pp. 429-434
    • González, E.A.1    Martin, K.J.2
  • 60
    • 34447119555 scopus 로고    scopus 로고
    • Calcium and vitamin D intakes in relation to risk of distal colorectal adenoma in women
    • Oh K., Willett W.C., Wu K., Fuchs C.S., Giovannucci E.L. Calcium and vitamin D intakes in relation to risk of distal colorectal adenoma in women. Am J Epidemiol 2007, 165:1178-1186.
    • (2007) Am J Epidemiol , vol.165 , pp. 1178-1186
    • Oh, K.1    Willett, W.C.2    Wu, K.3    Fuchs, C.S.4    Giovannucci, E.L.5
  • 61
    • 0030698698 scopus 로고    scopus 로고
    • Vitamin A stimulation of insulin secretion: effects on transglutaminase mRNA and activity using rat islets and insulin-secreting cells
    • Driscoll H.K., Adkins C.D., Chertow T.E., Cordle M.B., Matthews K.A., Chertow B.S. Vitamin A stimulation of insulin secretion: effects on transglutaminase mRNA and activity using rat islets and insulin-secreting cells. Pancreas 1997, 15:69-77.
    • (1997) Pancreas , vol.15 , pp. 69-77
    • Driscoll, H.K.1    Adkins, C.D.2    Chertow, T.E.3    Cordle, M.B.4    Matthews, K.A.5    Chertow, B.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.