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Volumn 114, Issue 3, 2006, Pages 381-388

Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice

Author keywords

Anti angiogenesis; Soluble Flt 1; Systemic injection; Targeted gene delivery; Tumor therapy

Indexed keywords

ANGIOGRAPHY; BIODIVERSITY; BIOLOGICAL ORGANS; COMPLEXATION; DRUG THERAPY; GENETIC ENGINEERING;

EID: 33748160118     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.05.029     Document Type: Article
Times cited : (83)

References (41)
  • 1
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P., and Jain R.K. Angiogenesis in cancer and other diseases. Nature 407 (2000) 249-257
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 2
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. Signaling vascular morphogenesis and maintenance. Science 277 (1997) 48-50
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 3
    • 0034090097 scopus 로고    scopus 로고
    • Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
    • Griffioen A.W., and Molema G. Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol. Rev. 52 (2000) 237-268
    • (2000) Pharmacol. Rev. , vol.52 , pp. 237-268
    • Griffioen, A.W.1    Molema, G.2
  • 5
    • 0032053767 scopus 로고    scopus 로고
    • Signaling angiogenesis and lymphangiogenesis
    • Korpelainen E.I., and Alitalo K. Signaling angiogenesis and lymphangiogenesis. Curr. Opin. Cell Biol. 10 (1998) 159-164
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 159-164
    • Korpelainen, E.I.1    Alitalo, K.2
  • 6
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N., and Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr. Rev. 18 (1997) 4-25
    • (1997) Endocr. Rev. , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 7
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G., Cohen T., Gengrinovitch S., and Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 13 (1999) 9-22
    • (1999) FASEB J. , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 8
    • 0030044984 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, a potent and selective angiogenic agent
    • Thomas K.A. Vascular endothelial growth factor, a potent and selective angiogenic agent. J. Biol. Chem. 271 (1996) 603-606
    • (1996) J. Biol. Chem. , vol.271 , pp. 603-606
    • Thomas, K.A.1
  • 9
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B., Shawver L.K., Plate K.H., Risau W., and Ullrich A. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367 (1994) 576-579
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 10
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall R.L., and Thomas K.A. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 10705-10709
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 11
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor FLT-1, and its heterodimerization with KDR
    • Kendall R.L., Wang G., and Thomas K.A. Identification of a natural soluble form of the vascular endothelial growth factor receptor FLT-1, and its heterodimerization with KDR. Biochem. Biophys. Res. Commun. 226 (1996) 324-328
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 13
    • 0032502843 scopus 로고    scopus 로고
    • Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
    • Kong H.L., Hecht D., Song W., Kovesdi I., Hackett N.R., Yayon A., and Crystal R.G. Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum. Gene Ther. 9 (1998) 823-833
    • (1998) Hum. Gene Ther. , vol.9 , pp. 823-833
    • Kong, H.L.1    Hecht, D.2    Song, W.3    Kovesdi, I.4    Hackett, N.R.5    Yayon, A.6    Crystal, R.G.7
  • 14
    • 0034655246 scopus 로고    scopus 로고
    • Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
    • Takayama K., Ueno H., Nakanishi Y., Sakamoto T., Inoue K., Shimizu K., Oohashi H., and Hara N. Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res. 60 (2000) 2169-2177
    • (2000) Cancer Res. , vol.60 , pp. 2169-2177
    • Takayama, K.1    Ueno, H.2    Nakanishi, Y.3    Sakamoto, T.4    Inoue, K.5    Shimizu, K.6    Oohashi, H.7    Hara, N.8
  • 16
    • 0036853181 scopus 로고    scopus 로고
    • An angiogenic, endothelial-cell-targeted polymeric gene carrier
    • Suh W., Han S.-o., Yu L., and Kim S.W. An angiogenic, endothelial-cell-targeted polymeric gene carrier. Mol. Ther. 6 (2002) 664-672
    • (2002) Mol. Ther. , vol.6 , pp. 664-672
    • Suh, W.1    Han, S.-o.2    Yu, L.3    Kim, S.W.4
  • 17
    • 23744483537 scopus 로고    scopus 로고
    • Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis
    • Kim W.J., Yockman J.W., Lee M., Jeong J.H., Kim Y.-H., and Kim S.W. Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis. J. Control. Release 106 (2005) 224-234
    • (2005) J. Control. Release , vol.106 , pp. 224-234
    • Kim, W.J.1    Yockman, J.W.2    Lee, M.3    Jeong, J.H.4    Kim, Y.-H.5    Kim, S.W.6
  • 18
    • 0035028214 scopus 로고    scopus 로고
    • Long-circulating vectors for the systemic delivery of genes
    • Fenske D.B., MacLachlan I., and Cullis P.R. Long-circulating vectors for the systemic delivery of genes. Curr. Opin. Mol. Ther. 3 (2001) 153-158
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 153-158
    • Fenske, D.B.1    MacLachlan, I.2    Cullis, P.R.3
  • 19
    • 0032959729 scopus 로고    scopus 로고
    • Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
    • Dash P.R., Read M.L., Barrett L.B., Wolfert M.A., and Seymour L.W. Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther. 6 (1999) 643-650
    • (1999) Gene Ther. , vol.6 , pp. 643-650
    • Dash, P.R.1    Read, M.L.2    Barrett, L.B.3    Wolfert, M.A.4    Seymour, L.W.5
  • 21
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap W., Pasqualini R., and Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279 (1998) 377-380
    • (1998) Science , vol.279 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 22
    • 0037105767 scopus 로고    scopus 로고
    • Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo
    • Zitzmann S., Ehemann V., and Schwab M. Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo. Cancer Res. 62 (2002) 5139-5143
    • (2002) Cancer Res. , vol.62 , pp. 5139-5143
    • Zitzmann, S.1    Ehemann, V.2    Schwab, M.3
  • 23
    • 0026505773 scopus 로고
    • Molecular and biological properties of the vascular endothelial growth factor family of proteins
    • Ferrara N., Houck K., Jakeman L., and Leung D.W. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr. Rev. 13 (1992) 18-32
    • (1992) Endocr. Rev. , vol.13 , pp. 18-32
    • Ferrara, N.1    Houck, K.2    Jakeman, L.3    Leung, D.W.4
  • 24
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim K.J., Li B., Winer J., Armanini M., Gillett N., Phillips H.S., and Ferrara N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362 (1993) 841-844
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6    Ferrara, N.7
  • 25
    • 0028842903 scopus 로고
    • Role of VEGF-flt-1 receptor system in normal and tumor angiogenesis
    • Shibuya M. Role of VEGF-flt-1 receptor system in normal and tumor angiogenesis. Adv. Cancer Res. 67 (1995) 281-316
    • (1995) Adv. Cancer Res. , vol.67 , pp. 281-316
    • Shibuya, M.1
  • 26
    • 2442446450 scopus 로고    scopus 로고
    • Suppression of lung metastasis of renal cell carcinoma by the intramuscular gene transfer of a soluble form of vascular endothelial growth factor receptor I
    • Yoshimura I., Mizuguchi Y., Miyajima A., Asano T., Tadakuma T., and Hayakawa M. Suppression of lung metastasis of renal cell carcinoma by the intramuscular gene transfer of a soluble form of vascular endothelial growth factor receptor I. J. Urol. 171 (2004) 2467-2470
    • (2004) J. Urol. , vol.171 , pp. 2467-2470
    • Yoshimura, I.1    Mizuguchi, Y.2    Miyajima, A.3    Asano, T.4    Tadakuma, T.5    Hayakawa, M.6
  • 29
  • 30
    • 1542298941 scopus 로고    scopus 로고
    • In vivo inhibition of tumor angiogenesis by a soluble VEGFR-1 fragment
    • Kou B., Li Y., Zhang L., Zhu G., Wang X., Li Y., Xia J., and Shi Y. In vivo inhibition of tumor angiogenesis by a soluble VEGFR-1 fragment. Exp. Mol. Pathol. 76 (2004) 129-137
    • (2004) Exp. Mol. Pathol. , vol.76 , pp. 129-137
    • Kou, B.1    Li, Y.2    Zhang, L.3    Zhu, G.4    Wang, X.5    Li, Y.6    Xia, J.7    Shi, Y.8
  • 31
    • 27744497800 scopus 로고    scopus 로고
    • Combinational antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma
    • Ohlfest J.R., Demorest Z.L., Motooka Y., Vengco I., Oh S., Chen E., Scappaticci F.A., Saplis R.J., Ekker S.C., Low W.C., Freese A.B., and Largaespada D.A. Combinational antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Mol. Ther. 12 (2005) 778-788
    • (2005) Mol. Ther. , vol.12 , pp. 778-788
    • Ohlfest, J.R.1    Demorest, Z.L.2    Motooka, Y.3    Vengco, I.4    Oh, S.5    Chen, E.6    Scappaticci, F.A.7    Saplis, R.J.8    Ekker, S.C.9    Low, W.C.10    Freese, A.B.11    Largaespada, D.A.12
  • 32
    • 2442473962 scopus 로고    scopus 로고
    • PEGylation enhances tumor targeting of plasmid DNA by an artificial cationized protein with repeated RGD sequences, Pronectin
    • Hosseinkhani H., and Tabata Y. PEGylation enhances tumor targeting of plasmid DNA by an artificial cationized protein with repeated RGD sequences, Pronectin. J. Control. Release 97 (2004) 157-171
    • (2004) J. Control. Release , vol.97 , pp. 157-171
    • Hosseinkhani, H.1    Tabata, Y.2
  • 35
    • 21244494846 scopus 로고    scopus 로고
    • Enhanced intracellular uptake of sterically stabilized liposomal doxorubicin in vitro resulting in improved antitumor activity in vivo
    • Xiong X.B., Huang Y., Lu W.L., Zhang H., Zhang X., and Zhang Q. Enhanced intracellular uptake of sterically stabilized liposomal doxorubicin in vitro resulting in improved antitumor activity in vivo. Pharm. Res. 22 (2005) 933-939
    • (2005) Pharm. Res. , vol.22 , pp. 933-939
    • Xiong, X.B.1    Huang, Y.2    Lu, W.L.3    Zhang, H.4    Zhang, X.5    Zhang, Q.6
  • 36
    • 25444471028 scopus 로고    scopus 로고
    • Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: in vitro and in vivo
    • Xiong X.B., Huang Y., Lu W.L., Zhang X., Zhang H., Nagai T., and Zhang Q. Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: in vitro and in vivo. J. Pharm. Sci. 94 (2005) 1782-1793
    • (2005) J. Pharm. Sci. , vol.94 , pp. 1782-1793
    • Xiong, X.B.1    Huang, Y.2    Lu, W.L.3    Zhang, X.4    Zhang, H.5    Nagai, T.6    Zhang, Q.7
  • 37
    • 0036568415 scopus 로고    scopus 로고
    • Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer
    • Iinuma H., Maruyama K., Okinaga K., Sasaki K., Sekine T., Ishida O., Ogiwara N., Johkura K., and Yonemura Y. Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer. Int. J. Cancer 99 (2002) 130-137
    • (2002) Int. J. Cancer , vol.99 , pp. 130-137
    • Iinuma, H.1    Maruyama, K.2    Okinaga, K.3    Sasaki, K.4    Sekine, T.5    Ishida, O.6    Ogiwara, N.7    Johkura, K.8    Yonemura, Y.9
  • 38
    • 4344586166 scopus 로고    scopus 로고
    • Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma
    • Turk M.J., Waters D.J., and Low P.S. Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma. Cancer Lett. 213 (2004) 165-172
    • (2004) Cancer Lett. , vol.213 , pp. 165-172
    • Turk, M.J.1    Waters, D.J.2    Low, P.S.3
  • 39
    • 13844262634 scopus 로고    scopus 로고
    • Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysopsonization
    • Bikram M., Lee M., Chang C.W., Janat-Amsbury M.M., Kern S.E., and Kim S.W. Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysopsonization. J. Control. Release 103 (2005) 221-233
    • (2005) J. Control. Release , vol.103 , pp. 221-233
    • Bikram, M.1    Lee, M.2    Chang, C.W.3    Janat-Amsbury, M.M.4    Kern, S.E.5    Kim, S.W.6
  • 40
    • 33344463203 scopus 로고    scopus 로고
    • Intestinal uptake and biodistribution of novel polymeric micelles after oral administration
    • Mathot F., van Beijsterveldt L., Preat V., Brewster M., and Arien A. Intestinal uptake and biodistribution of novel polymeric micelles after oral administration. J. Control. Release 111 (2006) 47-55
    • (2006) J. Control. Release , vol.111 , pp. 47-55
    • Mathot, F.1    van Beijsterveldt, L.2    Preat, V.3    Brewster, M.4    Arien, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.