메뉴 건너뛰기




Volumn 51, Issue , 2015, Pages 166-171

Puerarin attenuates learning and memory impairments and inhibits oxidative stress in STZ-induced SAD mice

Author keywords

Alzheimer's disease; Learning and memory; Oxidative stress; Puerarin; Streptozotocin

Indexed keywords

DONEPEZIL; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PUERARIN; STREPTOZOCIN; SUPEROXIDE DISMUTASE; ISOFLAVONE DERIVATIVE;

EID: 84946417075     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.10.010     Document Type: Article
Times cited : (56)

References (46)
  • 1
    • 60349128460 scopus 로고    scopus 로고
    • A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia
    • Agrawa R., Tyagi E., Shukla R., Nath C. A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia. Neuropharmacology 2009, 56(4):779-787.
    • (2009) Neuropharmacology , vol.56 , Issue.4 , pp. 779-787
    • Agrawa, R.1    Tyagi, E.2    Shukla, R.3    Nath, C.4
  • 2
    • 84899895001 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer's disease
    • Chen Z., Zhong C. Oxidative stress in Alzheimer's disease. Neurosci. Bull. 2014, 30(2):271-281.
    • (2014) Neurosci. Bull. , vol.30 , Issue.2 , pp. 271-281
    • Chen, Z.1    Zhong, C.2
  • 3
    • 0033899176 scopus 로고    scopus 로고
    • Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species
    • Dringen R., Gutterer J.M., Hirrlinger J. Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur. J. Biochem. 2000, 267(16):4912-4916.
    • (2000) Eur. J. Biochem. , vol.267 , Issue.16 , pp. 4912-4916
    • Dringen, R.1    Gutterer, J.M.2    Hirrlinger, J.3
  • 4
    • 38949103453 scopus 로고    scopus 로고
    • Aberrant insulin receptor signaling and amino acid homeostasis as a major cause of oxidative stress in aging
    • Droge W., Kinscherf R. Aberrant insulin receptor signaling and amino acid homeostasis as a major cause of oxidative stress in aging. Antioxid. Redox Signal. 2008, 10(4):661-668.
    • (2008) Antioxid. Redox Signal. , vol.10 , Issue.4 , pp. 661-668
    • Droge, W.1    Kinscherf, R.2
  • 5
    • 68849110235 scopus 로고    scopus 로고
    • Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
    • Dumont M., Wille E., Stack C., Calingasan N.Y., Beal M.F., Lin M.T. Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease. FASEB J. 2009, 23(8):2459-2466.
    • (2009) FASEB J. , vol.23 , Issue.8 , pp. 2459-2466
    • Dumont, M.1    Wille, E.2    Stack, C.3    Calingasan, N.Y.4    Beal, M.F.5    Lin, M.T.6
  • 6
    • 34247324303 scopus 로고    scopus 로고
    • Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
    • Grunblatt E., Salkovic-Petrisic M., Osmanovic J., Riederer P., Hoyer S. Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J. Neurochem. 2007, 101(3):757-770.
    • (2007) J. Neurochem. , vol.101 , Issue.3 , pp. 757-770
    • Grunblatt, E.1    Salkovic-Petrisic, M.2    Osmanovic, J.3    Riederer, P.4    Hoyer, S.5
  • 7
    • 84859429769 scopus 로고    scopus 로고
    • The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease
    • Hamilton A., Holscher C. The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease. Brain Res. 2012, 1449:83-93.
    • (2012) Brain Res. , vol.1449 , pp. 83-93
    • Hamilton, A.1    Holscher, C.2
  • 8
    • 0033380660 scopus 로고    scopus 로고
    • Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats
    • Hoyer S., Lannert H. Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats. Ann. N.Y. Acad. Sci. 1999, 893:301-303.
    • (1999) Ann. N.Y. Acad. Sci. , vol.893 , pp. 301-303
    • Hoyer, S.1    Lannert, H.2
  • 9
    • 84887995472 scopus 로고    scopus 로고
    • The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD
    • Hunter S., Arendt T., Brayne C. The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD. Mol. Neurobiol. 2013, 48(3):556-570.
    • (2013) Mol. Neurobiol. , vol.48 , Issue.3 , pp. 556-570
    • Hunter, S.1    Arendt, T.2    Brayne, C.3
  • 10
    • 77956359253 scopus 로고    scopus 로고
    • Alzheimer's disease, a multifactorial disorder seeking multitherapies
    • Iqbal K., Grundke-Iqbal I. Alzheimer's disease, a multifactorial disorder seeking multitherapies. Alzheimers Dement. 2010, 6(5):420-424.
    • (2010) Alzheimers Dement. , vol.6 , Issue.5 , pp. 420-424
    • Iqbal, K.1    Grundke-Iqbal, I.2
  • 11
    • 67649435873 scopus 로고    scopus 로고
    • Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
    • Ishrat T., Parveen K., Khan M.M., Khuwaja G., Khan M.B., Yousuf S., et al. Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res. 2009, 1281:117-127.
    • (2009) Brain Res. , vol.1281 , pp. 117-127
    • Ishrat, T.1    Parveen, K.2    Khan, M.M.3    Khuwaja, G.4    Khan, M.B.5    Yousuf, S.6
  • 12
    • 79955464184 scopus 로고    scopus 로고
    • S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type
    • Javed H., Khan M.M., Khan A., Vaibhav K., Ahmad A., Khuwaja G., et al. S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res. 2011, 1389:133-142.
    • (2011) Brain Res. , vol.1389 , pp. 133-142
    • Javed, H.1    Khan, M.M.2    Khan, A.3    Vaibhav, K.4    Ahmad, A.5    Khuwaja, G.6
  • 13
    • 84904401226 scopus 로고    scopus 로고
    • Aβ-HBc virus-like particles immunization without additional adjuvant ameliorates the learning and memory and reduces Aβ deposit in PDAPP mice
    • Jin H., Wang W., Zhao S., Yang W., Qian Y., Jia N., Feng G. Aβ-HBc virus-like particles immunization without additional adjuvant ameliorates the learning and memory and reduces Aβ deposit in PDAPP mice. Vaccine 2014, 32(35):4450-4456.
    • (2014) Vaccine , vol.32 , Issue.35 , pp. 4450-4456
    • Jin, H.1    Wang, W.2    Zhao, S.3    Yang, W.4    Qian, Y.5    Jia, N.6    Feng, G.7
  • 14
    • 84870065076 scopus 로고    scopus 로고
    • Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model
    • Khan M.B., Khan M.M., Khan A., Ahmed M.E., Ishrat T., Tabassum R., et al. Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model. Neurochem. Int. 2012, 61(7):1081-1093.
    • (2012) Neurochem. Int. , vol.61 , Issue.7 , pp. 1081-1093
    • Khan, M.B.1    Khan, M.M.2    Khan, A.3    Ahmed, M.E.4    Ishrat, T.5    Tabassum, R.6
  • 15
    • 84866717339 scopus 로고    scopus 로고
    • In vivo cross-sectional characterization of cerebral alterations induced by intracerebroventricular administration of streptozotocin
    • Kraska A., Santin M.D., Dorieux O., Joseph-Mathurin N., Bourrin E., Petit F., et al. In vivo cross-sectional characterization of cerebral alterations induced by intracerebroventricular administration of streptozotocin. PLoS ONE 2012, 7(9):e46196.
    • (2012) PLoS ONE , vol.7 , Issue.9 , pp. e46196
    • Kraska, A.1    Santin, M.D.2    Dorieux, O.3    Joseph-Mathurin, N.4    Bourrin, E.5    Petit, F.6
  • 17
    • 84878493432 scopus 로고    scopus 로고
    • Puerarin attenuates neuronal degeneration and blocks oxidative stress to elicit a neuroprotective effect on substantia nigra injury in 6-OHDA-lesioned rats
    • Li R., Zheng N., Liang T., He Q., Xu L. Puerarin attenuates neuronal degeneration and blocks oxidative stress to elicit a neuroprotective effect on substantia nigra injury in 6-OHDA-lesioned rats. Brain Res. 2013, 1517:28-35.
    • (2013) Brain Res. , vol.1517 , pp. 28-35
    • Li, R.1    Zheng, N.2    Liang, T.3    He, Q.4    Xu, L.5
  • 18
    • 84861687097 scopus 로고    scopus 로고
    • Protective effect of puerarin on β-amyloid-induced neurotoxicity in rat hippocampal neurons
    • Lin F., Xie B., Cai F., Wu G. Protective effect of puerarin on β-amyloid-induced neurotoxicity in rat hippocampal neurons. Arzneimittelforschung 2012, 62(4):187-193.
    • (2012) Arzneimittelforschung , vol.62 , Issue.4 , pp. 187-193
    • Lin, F.1    Xie, B.2    Cai, F.3    Wu, G.4
  • 19
    • 17444377148 scopus 로고    scopus 로고
    • Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?
    • Moreira P.I., Smith M.A., Zhu X., Honda K., Lee H.G., Aliev G., et al. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?. Drug News Perspect. 2005, 18(1):13-19.
    • (2005) Drug News Perspect. , vol.18 , Issue.1 , pp. 13-19
    • Moreira, P.I.1    Smith, M.A.2    Zhu, X.3    Honda, K.4    Lee, H.G.5    Aliev, G.6
  • 20
    • 84867672737 scopus 로고    scopus 로고
    • Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits
    • Ozkay U.D., Can O.D., Ozkay Y., Oztürk Y. Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits. Pharmacol. Rep. 2012, 64(4):834-847.
    • (2012) Pharmacol. Rep. , vol.64 , Issue.4 , pp. 834-847
    • Ozkay, U.D.1    Can, O.D.2    Ozkay, Y.3    Oztürk, Y.4
  • 22
    • 2942590320 scopus 로고    scopus 로고
    • Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry
    • Prasain J.K., Jones K., Brissie N., Moore R., Wyss J.M., Barnes S. Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 2004, 52(12):708-712.
    • (2004) J. Agric. Food Chem. , vol.52 , Issue.12 , pp. 708-712
    • Prasain, J.K.1    Jones, K.2    Brissie, N.3    Moore, R.4    Wyss, J.M.5    Barnes, S.6
  • 23
    • 0038240721 scopus 로고    scopus 로고
    • Causative and susceptibility genes for Alzheimer's disease: a review
    • Rocchi A., Pellegrini S., Siciliano G., Murri L. Causative and susceptibility genes for Alzheimer's disease: a review. Brain Res. Bull. 2003, 61(1):1-24.
    • (2003) Brain Res. Bull. , vol.61 , Issue.1 , pp. 1-24
    • Rocchi, A.1    Pellegrini, S.2    Siciliano, G.3    Murri, L.4
  • 24
    • 84872282685 scopus 로고    scopus 로고
    • What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer's disease, about the therapeutic strategies in Alzheimer's research
    • Salkovic-Petrisic M., Knezovic A., Hoyer S., Riederer P. What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer's disease, about the therapeutic strategies in Alzheimer's research. J. Neural Transm. 2013, 120(1):233-252.
    • (2013) J. Neural Transm. , vol.120 , Issue.1 , pp. 233-252
    • Salkovic-Petrisic, M.1    Knezovic, A.2    Hoyer, S.3    Riederer, P.4
  • 25
    • 38949164347 scopus 로고    scopus 로고
    • Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
    • Saxena G., Singh S.P., Agrawal R., Nath C. Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice. Eur. J. Pharmacol. 2008, 581(3):283-289.
    • (2008) Eur. J. Pharmacol. , vol.581 , Issue.3 , pp. 283-289
    • Saxena, G.1    Singh, S.P.2    Agrawal, R.3    Nath, C.4
  • 26
    • 84898767511 scopus 로고    scopus 로고
    • Agmatine improves cognitive dysfunction and prevents cell death in a streptozotocin-induced Alzheimer rat model
    • Song J., Hur B.E., Bokara K.K., Yang W., Cho H.J., Park K.A., et al. Agmatine improves cognitive dysfunction and prevents cell death in a streptozotocin-induced Alzheimer rat model. Yonsei Med. J. 2014, 55(3):689-699.
    • (2014) Yonsei Med. J. , vol.55 , Issue.3 , pp. 689-699
    • Song, J.1    Hur, B.E.2    Bokara, K.K.3    Yang, W.4    Cho, H.J.5    Park, K.A.6
  • 27
    • 17444398214 scopus 로고    scopus 로고
    • Effect of donepezil and lercanidipine on memory impairment induced by intracerebroventricular streptozotocin in rats
    • Sonkusare S., Srinivasan K., Kaul C., Ramarao P. Effect of donepezil and lercanidipine on memory impairment induced by intracerebroventricular streptozotocin in rats. Life Sci. 2005, 77(1):1-14.
    • (2005) Life Sci. , vol.77 , Issue.1 , pp. 1-14
    • Sonkusare, S.1    Srinivasan, K.2    Kaul, C.3    Ramarao, P.4
  • 29
    • 84872520228 scopus 로고    scopus 로고
    • Oxidative modification of brain proteins in Alzheimer's disease: perspective on future studies based on results of redox proteomics studies
    • Sultana R., Butterfield D.A. Oxidative modification of brain proteins in Alzheimer's disease: perspective on future studies based on results of redox proteomics studies. J. Alzheimers Dis. 2013, 33:S243-S251.
    • (2013) J. Alzheimers Dis. , vol.33 , pp. S243-S251
    • Sultana, R.1    Butterfield, D.A.2
  • 30
    • 79952837961 scopus 로고    scopus 로고
    • Impaired adaptive cellular responses to oxidative stress and the pathogenesis of Alzheimer's disease
    • Texel S.J., Mattson M.P. Impaired adaptive cellular responses to oxidative stress and the pathogenesis of Alzheimer's disease. Antioxid. Redox Signal. 2011, 14(8):1519-1534.
    • (2011) Antioxid. Redox Signal. , vol.14 , Issue.8 , pp. 1519-1534
    • Texel, S.J.1    Mattson, M.P.2
  • 31
    • 84875354777 scopus 로고    scopus 로고
    • 2013 Alzheimer's disease facts and figures
    • Alzheimer's Association
    • Thies W., Bleiler L. 2013 Alzheimer's disease facts and figures. Alzheimers Dement. 2013, 9(2):208-245. Alzheimer's Association.
    • (2013) Alzheimers Dement. , vol.9 , Issue.2 , pp. 208-245
    • Thies, W.1    Bleiler, L.2
  • 32
    • 83455186444 scopus 로고    scopus 로고
    • Antioxidant pathways in Alzheimer's disease: possibilities of intervention
    • Vina J., Lloret A., Giraldo E., Badia M.C., Alonso M.D. Antioxidant pathways in Alzheimer's disease: possibilities of intervention. Curr. Pharm. Des. 2011, 17(35):3861-3864.
    • (2011) Curr. Pharm. Des. , vol.17 , Issue.35 , pp. 3861-3864
    • Vina, J.1    Lloret, A.2    Giraldo, E.3    Badia, M.C.4    Alonso, M.D.5
  • 33
    • 40849093600 scopus 로고    scopus 로고
    • Genome-wide association studies in Alzheimer disease
    • Waring S.C., Rosenberg R.N. Genome-wide association studies in Alzheimer disease. Arch. Neurol. 2008, 65(3):329-334.
    • (2008) Arch. Neurol. , vol.65 , Issue.3 , pp. 329-334
    • Waring, S.C.1    Rosenberg, R.N.2
  • 34
    • 84903304059 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
    • Wang X., Wang W., Li L., Perry G., Lee H.G., Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim. Biophys. Acta 2014, 1842(8):1240-1247.
    • (2014) Biochim. Biophys. Acta , vol.1842 , Issue.8 , pp. 1240-1247
    • Wang, X.1    Wang, W.2    Li, L.3    Perry, G.4    Lee, H.G.5    Zhu, X.6
  • 35
    • 84904612269 scopus 로고    scopus 로고
    • Progress on the pharmacological research of puerarin: a review
    • Wei S.Y., Chen Y., Xu X.Y. Progress on the pharmacological research of puerarin: a review. Chin. J. Nat. Med. 2014, 12(6):407-414.
    • (2014) Chin. J. Nat. Med. , vol.12 , Issue.6 , pp. 407-414
    • Wei, S.Y.1    Chen, Y.2    Xu, X.Y.3
  • 36
    • 1542343843 scopus 로고    scopus 로고
    • Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity
    • Weinstock M., Shoham S. Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J. Neural.Transm. 2004, 111(3):347-366.
    • (2004) J. Neural.Transm. , vol.111 , Issue.3 , pp. 347-366
    • Weinstock, M.1    Shoham, S.2
  • 37
    • 79954422522 scopus 로고    scopus 로고
    • Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases
    • Wong K.H., Li G.Q., Li K.M., Razmovski-Naumovski V., Chan K. Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases. J. Ethnopharmacol. 2011, 134(3):584-607.
    • (2011) J. Ethnopharmacol. , vol.134 , Issue.3 , pp. 584-607
    • Wong, K.H.1    Li, G.Q.2    Li, K.M.3    Razmovski-Naumovski, V.4    Chan, K.5
  • 38
    • 60849084558 scopus 로고    scopus 로고
    • Protective effects and mechanism of puerarin on learning-memory disorder after global cerebral ischemia-reperfusion injury in rats
    • Wu H.Q., Guo H.N., Wang H.Q., Chang M.Z., Zhang G.L., Zhao Y.X. Protective effects and mechanism of puerarin on learning-memory disorder after global cerebral ischemia-reperfusion injury in rats. Chin. J. Integr. Med. 2009, 15(1):54-59.
    • (2009) Chin. J. Integr. Med. , vol.15 , Issue.1 , pp. 54-59
    • Wu, H.Q.1    Guo, H.N.2    Wang, H.Q.3    Chang, M.Z.4    Zhang, G.L.5    Zhao, Y.X.6
  • 39
    • 84883001365 scopus 로고    scopus 로고
    • Anti-diabetic effects of puerarin, isolated from Pueraria lobata (Willd.), on streptozotocin-diabetogenic mice through promoting insulin expression and ameliorating metabolic function
    • Wu K., Liang T., Duan X., Xu L., Zhang K., Li R. Anti-diabetic effects of puerarin, isolated from Pueraria lobata (Willd.), on streptozotocin-diabetogenic mice through promoting insulin expression and ameliorating metabolic function. Food Chem. Toxicol. 2013, 60:341-347.
    • (2013) Food Chem. Toxicol. , vol.60 , pp. 341-347
    • Wu, K.1    Liang, T.2    Duan, X.3    Xu, L.4    Zhang, K.5    Li, R.6
  • 40
    • 34548681835 scopus 로고    scopus 로고
    • Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats
    • Wu L., Qiao H., Li Y., Li L. Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats. Phytomedicine 2007, 14(10):652-658.
    • (2007) Phytomedicine , vol.14 , Issue.10 , pp. 652-658
    • Wu, L.1    Qiao, H.2    Li, Y.3    Li, L.4
  • 41
    • 3543015615 scopus 로고    scopus 로고
    • Effects of puerarin on learning-memory and amino acid transmitters of brain in ovariectomized mice
    • Xu X., Hu Y., Ruan Q. Effects of puerarin on learning-memory and amino acid transmitters of brain in ovariectomized mice. Planta Med. 2004, 70(7):627-631.
    • (2004) Planta Med. , vol.70 , Issue.7 , pp. 627-631
    • Xu, X.1    Hu, Y.2    Ruan, Q.3
  • 42
    • 34548646394 scopus 로고    scopus 로고
    • Effects of puerarin on synaptic structural modification in hippocampus of ovariectomized mice
    • Xu X., Zhang Z. Effects of puerarin on synaptic structural modification in hippocampus of ovariectomized mice. Planta Med. 2007, 73(10):1047-1053.
    • (2007) Planta Med. , vol.73 , Issue.10 , pp. 1047-1053
    • Xu, X.1    Zhang, Z.2
  • 43
    • 84887595537 scopus 로고    scopus 로고
    • The effects of perindopril on cognitive impairment induced by d-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress
    • Yang W.N., Han H., Hu X.D., Feng G.F., Qian Y.H. The effects of perindopril on cognitive impairment induced by d-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress. Pharmacol. Biochem. Behav. 2013, 114:31-36.
    • (2013) Pharmacol. Biochem. Behav. , vol.114 , pp. 31-36
    • Yang, W.N.1    Han, H.2    Hu, X.D.3    Feng, G.F.4    Qian, Y.H.5
  • 44
    • 52949146386 scopus 로고    scopus 로고
    • Puerarin protects PC12 cells against beta-amyloid-induced cell injury
    • Zhang H.Y., Liu Y.H., Wang H.Q., Xu J.H., Hu H.T. Puerarin protects PC12 cells against beta-amyloid-induced cell injury. Cell Biol. Int. 2008, 32(10):1230-1237.
    • (2008) Cell Biol. Int. , vol.32 , Issue.10 , pp. 1230-1237
    • Zhang, H.Y.1    Liu, Y.H.2    Wang, H.Q.3    Xu, J.H.4    Hu, H.T.5
  • 45
    • 84896404312 scopus 로고    scopus 로고
    • Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice
    • Zhou Y., Xie N., Li L., Zou Y., Zhang X., Dong M. Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. Int. J. Neuropsychopharmacol. 2014, 17(4):635-644.
    • (2014) Int. J. Neuropsychopharmacol. , vol.17 , Issue.4 , pp. 635-644
    • Zhou, Y.1    Xie, N.2    Li, L.3    Zou, Y.4    Zhang, X.5    Dong, M.6
  • 46
    • 84870798936 scopus 로고    scopus 로고
    • Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: involvement of the GSK-3β/Nrf2 signaling pathway
    • Zou Y., Hong B., Fan L., Zhou L., Liu Y., Wu Q., et al. Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: involvement of the GSK-3β/Nrf2 signaling pathway. Free Radical Res. 2013, 47(1):55-63.
    • (2013) Free Radical Res. , vol.47 , Issue.1 , pp. 55-63
    • Zou, Y.1    Hong, B.2    Fan, L.3    Zhou, L.4    Liu, Y.5    Wu, Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.