Ifit1 protects against lipopolysaccharide and D-galactosamine-induced fatal hepatitis by inhibiting activation of the JNK pathway

Journal of Infectious Diseases

Volumn 212, Issue 9, 2015, Pages 1509-1520

  Chang, Antao ^a,b   Chen, Yanan ^a   Shen, Wenzhi ^a   Gao, Ruifang ^a   Zhou, Wei ^a   Yang, Shuang ^a   Liu, Yanhua ^a   Luo, Yunping ^c   Chuang, Tsung Hsien ^d   Sun, Peiqing ^e   Liu, Chenghu ^a   Xiang, Rong ^a  

^a NANKAI UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

fatal hepatitis; Ifit1; JNK; LPS; TNF

Indexed keywords

ALANINE AMINOTRANSFERASE; AXIN; BIM PROTEIN; CASPASE 3; CELL PROTEIN; GALACTOSAMINE; IFIT1 PROTEIN; LIPOPOLYSACCHARIDE; MDFI PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BID; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; IFIT1 PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; HEPATITIS; IFIT1 GENE; IFIT2 GENE; IMMUNOBLOTTING; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CYTOLOGY; DEPENDOPARVOVIRUS; DISEASE MODEL; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; GENETICS; LIVER; LIVER CELL; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL LINE; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; HEPATITIS; HEPATOCYTES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84946136617     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv221     Document Type: Article

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