메뉴 건너뛰기




Volumn 8, Issue 6, 2013, Pages

Plasma Fibroblast Growth Factor 23 Concentration Is Increased and Predicts Mortality in Patients on the Liver-Transplant Waiting List

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; DIETHYLNITROSAMINE; FIBROBLAST GROWTH FACTOR 23; MESSENGER RNA; SODIUM; FIBROBLAST GROWTH FACTOR;

EID: 84879335593     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066182     Document Type: Article
Times cited : (57)

References (56)
  • 1
    • 0034697846 scopus 로고    scopus 로고
    • Identification of a novel FGF, FGF-21, preferentially expressed in the liver
    • Nishimura T, Nakatake Y, Konishi M, Itoh N, (2000) Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim Biophys Acta 1492: 203-206.
    • (2000) Biochim Biophys Acta , vol.1492 , pp. 203-206
    • Nishimura, T.1    Nakatake, Y.2    Konishi, M.3    Itoh, N.4
  • 2
    • 0026033573 scopus 로고
    • Liver contains heparin-binding growth factors as the major growth factor for cultured fibroblasts
    • Nagasaki T, Lieberman MA, (1991) Liver contains heparin-binding growth factors as the major growth factor for cultured fibroblasts. Hepatology 13: 6-14.
    • (1991) Hepatology , vol.13 , pp. 6-14
    • Nagasaki, T.1    Lieberman, M.A.2
  • 3
    • 8444223088 scopus 로고    scopus 로고
    • Bone as a source of FGF23: regulation by phosphate?
    • Mirams M, Robinson BG, Mason RS, Nelson AE, (2004) Bone as a source of FGF23: regulation by phosphate? Bone 35: 1192-1199.
    • (2004) Bone , vol.35 , pp. 1192-1199
    • Mirams, M.1    Robinson, B.G.2    Mason, R.S.3    Nelson, A.E.4
  • 5
    • 0141648346 scopus 로고    scopus 로고
    • Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis
    • Yu C, Wang F, Jin C, Huang X, Miller DL, et al. (2003) Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis. Am J Pathol 163: 1653-1662.
    • (2003) Am J Pathol , vol.163 , pp. 1653-1662
    • Yu, C.1    Wang, F.2    Jin, C.3    Huang, X.4    Miller, D.L.5
  • 6
    • 0031045831 scopus 로고    scopus 로고
    • Plasma level of basic fibroblast growth factor increases with progression of chronic liver disease
    • Jin-no K, Tanimizu M, Hyodo I, Kurimoto F, Yamashita T, (1997) Plasma level of basic fibroblast growth factor increases with progression of chronic liver disease. J Gastroenterol 32: 119-121.
    • (1997) J Gastroenterol , vol.32 , pp. 119-121
    • Jin-no, K.1    Tanimizu, M.2    Hyodo, I.3    Kurimoto, F.4    Yamashita, T.5
  • 7
    • 0036172292 scopus 로고    scopus 로고
    • Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression
    • Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW, (2002) Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression. Am J Pathol 160: 641-654.
    • (2002) Am J Pathol , vol.160 , pp. 641-654
    • Shackel, N.A.1    McGuinness, P.H.2    Abbott, C.A.3    Gorrell, M.D.4    McCaughan, G.W.5
  • 8
    • 19944415267 scopus 로고    scopus 로고
    • Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma
    • Uematsu S, Higashi T, Nouso K, Kariyama K, Nakamura S, et al. (2005) Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 20: 583-588.
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 583-588
    • Uematsu, S.1    Higashi, T.2    Nouso, K.3    Kariyama, K.4    Nakamura, S.5
  • 9
    • 79952212865 scopus 로고    scopus 로고
    • Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis
    • Gauglhofer C, Sagmeister S, Schrottmaier W, Fischer C, Rodgarkia-Dara C, et al. (2011) Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis. Hepatology 53: 854-864.
    • (2011) Hepatology , vol.53 , pp. 854-864
    • Gauglhofer, C.1    Sagmeister, S.2    Schrottmaier, W.3    Fischer, C.4    Rodgarkia-Dara, C.5
  • 10
  • 11
    • 19944433609 scopus 로고    scopus 로고
    • Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo
    • Saito H, Maeda A, Ohtomo S, Hirata M, Kusano K, et al. (2005) Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo. J Biol Chem 280: 2543-2549.
    • (2005) J Biol Chem , vol.280 , pp. 2543-2549
    • Saito, H.1    Maeda, A.2    Ohtomo, S.3    Hirata, M.4    Kusano, K.5
  • 12
    • 14344279878 scopus 로고    scopus 로고
    • Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
    • Shimada T, Mizutani S, Muto T, Yoneya T, Hino R, et al. (2001) Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci U S A 98: 6500-6505.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6500-6505
    • Shimada, T.1    Mizutani, S.2    Muto, T.3    Yoneya, T.4    Hino, R.5
  • 13
    • 0037462746 scopus 로고    scopus 로고
    • Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production
    • Saito H, Kusano K, Kinosaki M, Ito H, Hirata M, et al. (2003) Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production. J Biol Chem 278: 2206-2211.
    • (2003) J Biol Chem , vol.278 , pp. 2206-2211
    • Saito, H.1    Kusano, K.2    Kinosaki, M.3    Ito, H.4    Hirata, M.5
  • 14
    • 2142746439 scopus 로고    scopus 로고
    • FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis
    • Shimada T, Hasegawa H, Yamazaki Y, Muto T, Hino R, et al. (2004) FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 19: 429-435.
    • (2004) J Bone Miner Res , vol.19 , pp. 429-435
    • Shimada, T.1    Hasegawa, H.2    Yamazaki, Y.3    Muto, T.4    Hino, R.5
  • 15
    • 18744371012 scopus 로고    scopus 로고
    • Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia
    • Yamazaki Y, Okazaki R, Shibata M, Hasegawa Y, Satoh K, et al. (2002) Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia. J Clin Endocrinol Metab 87: 4957-4960.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4957-4960
    • Yamazaki, Y.1    Okazaki, R.2    Shibata, M.3    Hasegawa, Y.4    Satoh, K.5
  • 16
    • 50249114540 scopus 로고    scopus 로고
    • Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23
    • Yamazaki Y, Tamada T, Kasai N, Urakawa I, Aono Y, et al. (2008) Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23. J Bone Miner Res 23: 1509-1518.
    • (2008) J Bone Miner Res , vol.23 , pp. 1509-1518
    • Yamazaki, Y.1    Tamada, T.2    Kasai, N.3    Urakawa, I.4    Aono, Y.5
  • 17
    • 15944376583 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men
    • Ferrari SL, Bonjour JP, Rizzoli R, (2005) Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab 90: 1519-1524.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1519-1524
    • Ferrari, S.L.1    Bonjour, J.P.2    Rizzoli, R.3
  • 19
    • 28444486604 scopus 로고    scopus 로고
    • 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport
    • Kolek OI, Hines ER, Jones MD, LeSueur LK, Lipko MA, et al. (2005) 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. Am J Physiol Gastrointest Liver Physiol 289: G1036-1042.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Kolek, O.I.1    Hines, E.R.2    Jones, M.D.3    LeSueur, L.K.4    Lipko, M.A.5
  • 21
    • 33747719260 scopus 로고    scopus 로고
    • Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men
    • Antoniucci DM, Yamashita T, Portale AA, (2006) Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men. J Clin Endocrinol Metab 91: 3144-3149.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3144-3149
    • Antoniucci, D.M.1    Yamashita, T.2    Portale, A.A.3
  • 22
    • 27744545673 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
    • Gutierrez O, Isakova T, Rhee E, Shah A, Holmes J, et al. (2005) Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol 16: 2205-2215.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2205-2215
    • Gutierrez, O.1    Isakova, T.2    Rhee, E.3    Shah, A.4    Holmes, J.5
  • 23
    • 0344945402 scopus 로고    scopus 로고
    • Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers
    • Larsson T, Nisbeth U, Ljunggren O, Juppner H, Jonsson KB, (2003) Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int 64: 2272-2279.
    • (2003) Kidney Int , vol.64 , pp. 2272-2279
    • Larsson, T.1    Nisbeth, U.2    Ljunggren, O.3    Juppner, H.4    Jonsson, K.B.5
  • 25
    • 69249106380 scopus 로고    scopus 로고
    • High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients
    • Jean G, Terrat JC, Vanel T, Hurot JM, Lorriaux C, et al. (2009) High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients. Nephrol Dial Transplant 24: 2792-2796.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2792-2796
    • Jean, G.1    Terrat, J.C.2    Vanel, T.3    Hurot, J.M.4    Lorriaux, C.5
  • 26
    • 49249104701 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
    • Gutierrez OM, Mannstadt M, Isakova T, Rauh-Hain JA, Tamez H, et al. (2008) Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 359: 584-592.
    • (2008) N Engl J Med , vol.359 , pp. 584-592
    • Gutierrez, O.M.1    Mannstadt, M.2    Isakova, T.3    Rauh-Hain, J.A.4    Tamez, H.5
  • 27
    • 84875942739 scopus 로고    scopus 로고
    • Higher fibroblast growth factor-23 increases the risk of all-cause and cardiovascular mortality in the community
    • Ärnlöv J, Carlsson AC, Sundström J, Ingelsson E, Larsson A, et al. (2012) Higher fibroblast growth factor-23 increases the risk of all-cause and cardiovascular mortality in the community. Kidney International.
    • (2012) Kidney International
    • Ärnlöv, J.1    Carlsson, A.C.2    Sundström, J.3    Ingelsson, E.4    Larsson, A.5
  • 28
    • 84865434484 scopus 로고    scopus 로고
    • C-terminal FGF23 is a strong predictor of survival in systolic heart failure
    • Gruson D, Lepoutre T, Ketelslegers J-M, Cumps J, Ahn SA, et al. (2012) C-terminal FGF23 is a strong predictor of survival in systolic heart failure. Peptides 37: 258-262.
    • (2012) Peptides , vol.37 , pp. 258-262
    • Gruson, D.1    Lepoutre, T.2    Ketelslegers, J.-M.3    Cumps, J.4    Ahn, S.A.5
  • 29
    • 77952996999 scopus 로고    scopus 로고
    • The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study
    • Parker BD, Schurgers LJ, Brandenburg VM, Christenson RH, Vermeer C, et al. (2010) The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study. Ann Intern Med 152: 640-648.
    • (2010) Ann Intern Med , vol.152 , pp. 640-648
    • Parker, B.D.1    Schurgers, L.J.2    Brandenburg, V.M.3    Christenson, R.H.4    Vermeer, C.5
  • 30
    • 79958724181 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
    • Isakova T, Xie H, Yang W, Xie D, Anderson AH, et al. (2011) Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA 305: 2432-2439.
    • (2011) JAMA , vol.305 , pp. 2432-2439
    • Isakova, T.1    Xie, H.2    Yang, W.3    Xie, D.4    Anderson, A.H.5
  • 32
    • 34548497123 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study
    • Fliser D, Kollerits B, Neyer U, Ankerst DP, Lhotta K, et al. (2007) Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol 18: 2600-2608.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2600-2608
    • Fliser, D.1    Kollerits, B.2    Neyer, U.3    Ankerst, D.P.4    Lhotta, K.5
  • 33
    • 33947428441 scopus 로고    scopus 로고
    • The model for end-stage liver disease (MELD)
    • Kamath PS, Kim WR, (2007) The model for end-stage liver disease (MELD). Hepatology 45: 797-805.
    • (2007) Hepatology , vol.45 , pp. 797-805
    • Kamath, P.S.1    Kim, W.R.2
  • 34
    • 33646372427 scopus 로고    scopus 로고
    • Evidence-based incorporation of serum sodium concentration into MELD
    • Biggins SW, Kim WR, Terrault NA, Saab S, Balan V, et al. (2006) Evidence-based incorporation of serum sodium concentration into MELD. Gastroenterology 130: 1652-1660.
    • (2006) Gastroenterology , vol.130 , pp. 1652-1660
    • Biggins, S.W.1    Kim, W.R.2    Terrault, N.A.3    Saab, S.4    Balan, V.5
  • 35
  • 36
    • 4644301244 scopus 로고    scopus 로고
    • Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death
    • Heuman DM, Abou-Assi SG, Habib A, Williams LM, Stravitz RT, et al. (2004) Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death. Hepatology 40: 802-810.
    • (2004) Hepatology , vol.40 , pp. 802-810
    • Heuman, D.M.1    Abou-Assi, S.G.2    Habib, A.3    Williams, L.M.4    Stravitz, R.T.5
  • 37
    • 16244422677 scopus 로고    scopus 로고
    • Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone
    • Ruf AE, Kremers WK, Chavez LL, Descalzi VI, Podesta LG, et al. (2005) Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone. Liver Transpl 11: 336-343.
    • (2005) Liver Transpl , vol.11 , pp. 336-343
    • Ruf, A.E.1    Kremers, W.K.2    Chavez, L.L.3    Descalzi, V.I.4    Podesta, L.G.5
  • 39
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 42
    • 1542532754 scopus 로고    scopus 로고
    • A Proportional Hazards Model for the Subdistribution of a Competing Risk
    • FIne JP, Gray RJ, (1999) A Proportional Hazards Model for the Subdistribution of a Competing Risk. Journal of the American Statistical Association 94: 496-509.
    • (1999) Journal of the American Statistical Association , vol.94 , pp. 496-509
    • FIne, J.P.1    Gray, R.J.2
  • 43
    • 0030052899 scopus 로고    scopus 로고
    • Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club
    • Arroyo V, Gines P, Gerbes AL, Dudley FJ, Gentilini P, et al. (1996) Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. Hepatology 23: 164-176.
    • (1996) Hepatology , vol.23 , pp. 164-176
    • Arroyo, V.1    Gines, P.2    Gerbes, A.L.3    Dudley, F.J.4    Gentilini, P.5
  • 44
    • 50949127481 scopus 로고    scopus 로고
    • Hyponatremia and mortality among patients on the liver-transplant waiting list
    • Kim WR, Biggins SW, Kremers WK, Wiesner RH, Kamath PS, et al. (2008) Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med 359: 1018-1026.
    • (2008) N Engl J Med , vol.359 , pp. 1018-1026
    • Kim, W.R.1    Biggins, S.W.2    Kremers, W.K.3    Wiesner, R.H.4    Kamath, P.S.5
  • 45
    • 70449359551 scopus 로고    scopus 로고
    • Limitations of the MELD score in predicting mortality or need for removal from waiting list in patients awaiting liver transplantation
    • Gotthardt D, Weiss KH, Baumgartner M, Zahn A, Stremmel W, et al. (2009) Limitations of the MELD score in predicting mortality or need for removal from waiting list in patients awaiting liver transplantation. BMC Gastroenterol 9: 72.
    • (2009) BMC Gastroenterol , vol.9 , pp. 72
    • Gotthardt, D.1    Weiss, K.H.2    Baumgartner, M.3    Zahn, A.4    Stremmel, W.5
  • 46
    • 22744437717 scopus 로고    scopus 로고
    • Model for End-Stage Liver Disease (MELD) predicts nontransplant surgical mortality in patients with cirrhosis
    • Northup PG, Wanamaker RC, Lee VD, Adams RB, Berg CL, (2005) Model for End-Stage Liver Disease (MELD) predicts nontransplant surgical mortality in patients with cirrhosis. Ann Surg 242: 244-251.
    • (2005) Ann Surg , vol.242 , pp. 244-251
    • Northup, P.G.1    Wanamaker, R.C.2    Lee, V.D.3    Adams, R.B.4    Berg, C.L.5
  • 47
    • 34548118399 scopus 로고    scopus 로고
    • MELD score and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation
    • Londono MC, Cardenas A, Guevara M, Quinto L, de Las Heras D, et al. (2007) MELD score and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation. Gut 56: 1283-1290.
    • (2007) Gut , vol.56 , pp. 1283-1290
    • Londono, M.C.1    Cardenas, A.2    Guevara, M.3    Quinto, L.4    de Las Heras, D.5
  • 48
    • 34548187264 scopus 로고    scopus 로고
    • An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis
    • Luca A, Angermayr B, Bertolini G, Koenig F, Vizzini G, et al. (2007) An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis. Liver Transpl 13: 1174-1180.
    • (2007) Liver Transpl , vol.13 , pp. 1174-1180
    • Luca, A.1    Angermayr, B.2    Bertolini, G.3    Koenig, F.4    Vizzini, G.5
  • 51
    • 80755172594 scopus 로고    scopus 로고
    • The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation
    • Seiler S, Cremers B, Rebling NM, Hornof F, Jeken J, et al. (2011) The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation. European Heart Journal.
    • (2011) European Heart Journal
    • Seiler, S.1    Cremers, B.2    Rebling, N.M.3    Hornof, F.4    Jeken, J.5
  • 52
    • 83155175908 scopus 로고    scopus 로고
    • Fibroblast Growth Factor 23, Cardiovascular Disease Risk Factors, and Phosphorus Intake in the Health Professionals Follow-up Study
    • Gutierrez OM, Wolf M, Taylor EN (2011) Fibroblast Growth Factor 23, Cardiovascular Disease Risk Factors, and Phosphorus Intake in the Health Professionals Follow-up Study. Clin J Am Soc Nephrol.
    • (2011) Clin J Am Soc Nephrol
    • Gutierrez, O.M.1    Wolf, M.2    Taylor, E.N.3
  • 55
    • 0033763097 scopus 로고    scopus 로고
    • Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
    • Consortium A, (2000) Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. Nat Genet 26: 345-348.
    • (2000) Nat Genet , vol.26 , pp. 345-348
    • Consortium, A.1
  • 56
    • 18444375871 scopus 로고    scopus 로고
    • Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo
    • Shimada T, Muto T, Urakawa I, Yoneya T, Yamazaki Y, et al. (2002) Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo. Endocrinology 143: 3179-3182.
    • (2002) Endocrinology , vol.143 , pp. 3179-3182
    • Shimada, T.1    Muto, T.2    Urakawa, I.3    Yoneya, T.4    Yamazaki, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.