-
1
-
-
84922947461
-
Methods for the quantification of lysosomal membrane permeabilization: A hallmark of lysosomal cell death
-
(ed Platt F, Platt N, Academic Press, Waltham
-
Aits S, Jäättelä M, Nylandsted J. 2015. Methods for the quantification of lysosomal membrane permeabilization: A hallmark of lysosomal cell death. In Lysosomes and Lysosomal Diseases (ed Platt F, Platt N), pp. 261–286. Academic Press, Waltham.
-
(2015)
Lysosomes and Lysosomal Diseases
, pp. 261-286
-
-
Aits, S.1
Jäättelä, M.2
Nylandsted, J.3
-
2
-
-
0010850232
-
Modifications to the Gomori acid phosphatase technique for controlled temperature frozen sections
-
Bitensky L. 1963. Modifications to the Gomori acid phosphatase technique for controlled temperature frozen sections. Q J Micr Sci 104: 193–196.
-
(1963)
Q J Micr Sci
, vol.104
, pp. 193-196
-
-
Bitensky, L.1
-
3
-
-
54949137644
-
Lysosomal membrane permeabilization in cell death
-
Boya P, Kroemer G. 2008. Lysosomal membrane permeabilization in cell death. Oncogene 27: 6434–6451.
-
(2008)
Oncogene
, vol.27
, pp. 6434-6451
-
-
Boya, P.1
Kroemer, G.2
-
4
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini JL, Metivier D, Ojcius DM, Jäättelä M, Kroemer G. 2003. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med 197: 1323–1334.
-
(2003)
J Exp Med
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Reau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
Ojcius, D.M.7
Jäättelä, M.8
Kroemer, G.9
-
5
-
-
0030757986
-
Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts
-
Brunk UT, Dalen H, Roberg K, Hellquist HB. 1997. Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts. Free Radic Biol Med 23: 616–626.
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 616-626
-
-
Brunk, U.T.1
Dalen, H.2
Roberg, K.3
Hellquist, H.B.4
-
7
-
-
0942265544
-
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins
-
Cirman T, Oresic K, Mazovec GD, Turk V, Reed JC, Myers RM, Salvesen GS, Turk B. 2004. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem 279: 3578–3587.
-
(2004)
J Biol Chem
, vol.279
, pp. 3578-3587
-
-
Cirman, T.1
Oresic, K.2
Mazovec, G.D.3
Turk, V.4
Reed, J.C.5
Myers, R.M.6
Salvesen, G.S.7
Turk, B.8
-
8
-
-
0021040946
-
Lysosomes revisited
-
de Duve C. 1983. Lysosomes revisited. Eur J Biochem 137: 391–397.
-
(1983)
Eur J Biochem
, vol.137
, pp. 391-397
-
-
de Duve, C.1
-
9
-
-
77049229661
-
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue
-
de Duve C, Pressman BC, Gianetto R, Wattiaux R, Appelmans F. 1955. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J 60: 604–617.
-
(1955)
Biochem J
, vol.60
, pp. 604-617
-
-
de Duve, C.1
Pressman, B.C.2
Gianetto, R.3
Wattiaux, R.4
Appelmans, F.5
-
10
-
-
84943241566
-
Visualizing lysosomal membrane permeabilization by fluorescent dextran release
-
Ellegaard A-M, Jäättelä M, Nylandsted J. 2015. Visualizing lysosomal membrane permeabilization by fluorescent dextran release. Cold Spring Harb Protoc doi: 10.1101/pdb.prot086173.
-
(2015)
Cold Spring Harb Protoc
-
-
Ellegaard, A.-M.1
Jäättelä, M.2
Nylandsted, J.3
-
11
-
-
3442880143
-
Sensitization to the lysosomal cell death pathway upon immortalization and transformation
-
Fehrenbacher N, Gyrd-Hansen M, Poulsen B, Felbor U, Kallunki T, Boes M, Weber E, Leist M, Jäättelä M. 2004. Sensitization to the lysosomal cell death pathway upon immortalization and transformation. Cancer Res 64: 5301–5310.
-
(2004)
Cancer Res
, vol.64
, pp. 5301-5310
-
-
Fehrenbacher, N.1
Gyrd-Hansen, M.2
Poulsen, B.3
Felbor, U.4
Kallunki, T.5
Boes, M.6
Weber, E.7
Leist, M.8
Jäättelä, M.9
-
12
-
-
0018656598
-
Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents
-
Firestone RA, Pisano JM, Bonney RJ. 1979. Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents. J Med Chem 22: 1130–1133.
-
(1979)
J Med Chem
, vol.22
, pp. 1130-1133
-
-
Firestone, R.A.1
Pisano, J.M.2
Bonney, R.J.3
-
13
-
-
0035947776
-
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
-
Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, Elling F, Leist M, Jäättelä M. 2001. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 153: 999–1010.
-
(2001)
J Cell Biol
, vol.153
, pp. 999-1010
-
-
Foghsgaard, L.1
Wissing, D.2
Mauch, D.3
Lademann, U.4
Bastholm, L.5
Boes, M.6
Elling, F.7
Leist, M.8
Jäättelä, M.9
-
15
-
-
84943241045
-
A method to monitor lysosomal membrane permeabilization by immunocytochemistry
-
Groth-Pedersen L, Jäättelä M, Nylandsted J. 2015. A method to monitor lysosomal membrane permeabilization by immunocytochemistry. Cold Spring Harb Protoc doi: 10.1101/pdb.prot086181.
-
(2015)
Cold Spring Harb Protoc
-
-
Groth-Pedersen, L.1
Jäättelä, M.2
Nylandsted, J.3
-
16
-
-
84946090399
-
Quantification of lysosomal membrane permeabilization by cytosolic cathepsin and β-N-acetyl-glucosaminidase activity measurements
-
Jäättelä M, Nylandsted J. 2015. Quantification of lysosomal membrane permeabilization by cytosolic cathepsin and β-N-acetyl-glucosaminidase activity measurements. Cold Spring Harb Protoc doi: 10.1101/pdb.prot086165.
-
(2015)
Cold Spring Harb Protoc
-
-
Jäättelä, M.1
Nylandsted, J.2
-
17
-
-
0035887215
-
Sphingosine-induced apoptosis is dependent on lysosomal proteases
-
Kagedal K, Zhao M, Svensson I, Brunk UT. 2001. Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem J 359: 335–343.
-
(2001)
Biochem J
, vol.359
, pp. 335-343
-
-
Kagedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
18
-
-
84876664386
-
Cancer-associated lysosomal changes: Friends or foes
-
Kallunki T, Olsen OD, Jäättelä M. 2013. Cancer-associated lysosomal changes: Friends or foes. Oncogene 32: 1995–2004.
-
(2013)
Oncogene
, vol.32
, pp. 1995-2004
-
-
Kallunki, T.1
Olsen, O.D.2
Jäättelä, M.3
-
19
-
-
62949128915
-
Lysosomal involvement in cell death and cancer
-
Kirkegaard T, Jäättelä M. 2009. Lysosomal involvement in cell death and cancer. Biochim Biophys Acta 1793: 746–754.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 746-754
-
-
Kirkegaard, T.1
Jäättelä, M.2
-
20
-
-
75749102680
-
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology
-
Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, et al. 2010. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature 463: 549–553.
-
(2010)
Nature
, vol.463
, pp. 549-553
-
-
Kirkegaard, T.1
Roth, A.G.2
Petersen, N.H.3
Mahalka, A.K.4
Olsen, O.D.5
Moilanen, I.6
Zylicz, A.7
Knudsen, J.8
Sandhoff, K.9
Arenz, C.10
-
21
-
-
77951924919
-
Lysosomal degradation of membrane lipids
-
Kolter T, Sandhoff K. 2010. Lysosomal degradation of membrane lipids. FEBS Lett 584: 1700–1712.
-
(2010)
FEBS Lett
, vol.584
, pp. 1700-1712
-
-
Kolter, T.1
Sandhoff, K.2
-
22
-
-
79952257741
-
Stat3 controls lysosomal-mediated cell death in vivo
-
Kreuzaler PA, Staniszewska AD, Li W, Omidvar N, Kedjouar B, Turkson J, Poli V, Flavell RA, Clarkson RW, Watson CJ. 2011. Stat3 controls lysosomal-mediated cell death in vivo. Nat Cell Biol 13: 303–309.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 303-309
-
-
Kreuzaler, P.A.1
Staniszewska, A.D.2
Li, W.3
Omidvar, N.4
Kedjouar, B.5
Turkson, J.6
Poli, V.7
Flavell, R.A.8
Clarkson, R.W.9
Watson, C.J.10
-
23
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jäättelä M. 2005. Lysosomes and autophagy in cell death control. Nat Rev Cancer 5: 886–897.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jäättelä, M.2
-
24
-
-
80255137555
-
The role of lysosomes in iron metabolism and recycling
-
Kurz T, Eaton JW, Brunk UT. 2011. The role of lysosomes in iron metabolism and recycling. Int J Biochem Cell Biol 43: 1686–1697.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 1686-1697
-
-
Kurz, T.1
Eaton, J.W.2
Brunk, U.T.3
-
25
-
-
0027469618
-
Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility
-
Link G, Pinson A, Hershko C. 1993. Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility. J Lab Clin Med 121: 127–134.
-
(1993)
J Lab Clin Med
, vol.121
, pp. 127-134
-
-
Link, G.1
Pinson, A.2
Hershko, C.3
-
26
-
-
0031716874
-
Tumor cell membrane cathepsin B
-
Moin K, Cao L, Day NA, Koblinski JE, Sloane BF. 1998. Tumor cell membrane cathepsin B. Biol Chem 379: 1093–1099.
-
(1998)
Biol Chem
, vol.379
, pp. 1093-1099
-
-
Moin, K.1
Cao, L.2
Day, N.A.3
Koblinski, J.E.4
Sloane, B.F.5
-
27
-
-
4344651318
-
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
-
Nylandsted J, Gyrd-Hansen M, Danielewicz A, Fehrenbacher N, Lademann U, Hoyer-Hansen M, Weber E, Multhoff G, Rohde M, Jäättelä M. 2004. Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med 200: 425–435.
-
(2004)
J Exp Med
, vol.200
, pp. 425-435
-
-
Nylandsted, J.1
Gyrd-Hansen, M.2
Danielewicz, A.3
Fehrenbacher, N.4
Lademann, U.5
Hoyer-Hansen, M.6
Weber, E.7
Multhoff, G.8
Rohde, M.9
Jäättelä, M.10
-
28
-
-
37549070672
-
Cysteine cathepsin proteases as pharmacological targets in cancer
-
Palermo C, Joyce JA. 2008. Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol Sci 29: 22–28.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 22-28
-
-
Palermo, C.1
Joyce, J.A.2
-
29
-
-
62949097187
-
Delivery of endocytosed membrane proteins to the lysosome
-
Pryor PR, Luzio JP. 2009. Delivery of endocytosed membrane proteins to the lysosome. Biochim Biophys Acta 1793: 615–624.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 615-624
-
-
Pryor, P.R.1
Luzio, J.P.2
-
30
-
-
69249227502
-
Lysosome biogenesis and lysosomalmembrane proteins: Trafficking meets function
-
Saftig P, Klumperman J. 2009. Lysosome biogenesis and lysosomalmembrane proteins: Trafficking meets function. Nat Rev Mol Cell Biol 10: 623–635.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 623-635
-
-
Saftig, P.1
Klumperman, J.2
-
31
-
-
0032898735
-
Nonspecific effects of methyl ketone peptide inhibitors of caspases
-
Schotte P, Declercq W, Van Huffel S, Vandenabeele P, Beyaert R. 1999. Nonspecific effects of methyl ketone peptide inhibitors of caspases. FEBS Lett 442: 117–121.
-
(1999)
FEBS Lett
, vol.442
, pp. 117-121
-
-
Schotte, P.1
Declercq, W.2
Van Huffel, S.3
Vandenabeele, P.4
Beyaert, R.5
-
32
-
-
0031766546
-
SCCA1 and SCCA2 are proteinase inhibitors that map to the serpin cluster at 18q21.3
-
Silverman GA, Bartuski AJ, Cataltepe S, Gornstein ER, Kamachi Y, Schick C, Uemura Y. 1998. SCCA1 and SCCA2 are proteinase inhibitors that map to the serpin cluster at 18q21.3. Tumour Biol 19: 480–487.
-
(1998)
Tumour Biol
, vol.19
, pp. 480-487
-
-
Silverman, G.A.1
Bartuski, A.J.2
Cataltepe, S.3
Gornstein, E.R.4
Kamachi, Y.5
Schick, C.6
Uemura, Y.7
-
33
-
-
34250020188
-
Lysosomal cysteine cathepsins: Signaling pathways in apoptosis
-
Stoka V, Turk V, Turk B. 2007. Lysosomal cysteine cathepsins: Signaling pathways in apoptosis. Biol Chem 388: 555–560.
-
(2007)
Biol Chem
, vol.388
, pp. 555-560
-
-
Stoka, V.1
Turk, V.2
Turk, B.3
-
35
-
-
38649084746
-
Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion
-
Vasiljeva O, Turk B. 2008. Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion. Biochimie 90: 380–386.
-
(2008)
Biochimie
, vol.90
, pp. 380-386
-
-
Vasiljeva, O.1
Turk, B.2
|