Targeting the noradrenergic system in posttraumatic stress disorder: A systematic review and meta-analysis of prazosin trials

Current Drug Targets

Volumn 16, Issue 10, 2015, Pages 1094-1106

  de Berardis, Domenico ^a,b   Marini, Stefano ^a,b   Serroni, Nicola ^b   Iasevoli, Felice ^c   Tomasetti, Carmine ^c   de Bartolomeis, Andrea ^c   Mazza, Monica ^d   Tempesta, Daniela ^d   Valchera, Alessandro ^e   Fornaro, Michele ^f,g   Pompili, Maurizio ^h   Sepede, Gianna ^b,i   Vellante, Federica ^a,b   Orsolini, Laura ^j,k   Martinotti, Giovanni ^b   Di Giannantonio, Massimo ^b  

^a Hospital G Mazzini   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF L'AQUILA   (Italy)

^e Hermanas Hospitalarias   (Italy)

^f UNIVERSITY OF CATANIA   (Italy)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h SAPIENZA UNIVERSITY OF ROME   (Italy)

ⁱ UNIVERSITY OF BARI   (Italy)

^j UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^k UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

more..

Author keywords

Efficacy; Hyperarousal; Nightmares; Noradrenergic system; Post traumatic stress disorder; Prazosin; Tolerability

Indexed keywords

PLACEBO; PRAZOSIN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; NORADRENALIN;

CLINICAL GLOBAL IMPRESSION SCALE; DIZZINESS; DREAM; DROWSINESS; DRUG EFFICACY; DRUG TOLERABILITY; DSM-IV-TR; FATIGUE; HAMILTON DEPRESSION RATING SCALE; HEADACHE; HUMAN; MENTAL DISEASE ASSESSMENT; META ANALYSIS; NON NIGHTMARE DISTRESSED AWAKENING; NONHUMAN; NORADRENERGIC SYSTEM; NOSE OBSTRUCTION; ORTHOSTATIC HYPOTENSION; PITTSBURGH SLEEP QUALITY INDEX; POSTTRAUMATIC STRESS DISORDER; PUBLICATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; XEROSTOMIA; METABOLISM; NEUROIMAGING; PSYCHOLOGY; SLEEP WAKE DISORDERS; STRESS DISORDERS, POST-TRAUMATIC; TREATMENT OUTCOME;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; HUMANS; NEUROIMAGING; NOREPINEPHRINE; PRAZOSIN; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SLEEP WAKE DISORDERS; STRESS DISORDERS, POST-TRAUMATIC; TREATMENT OUTCOME;

EID: 84945910436     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/1389450116666150506114108     Document Type: Review

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